DK167218B1 - Aminoacyllabdaner, fremgangsmaade til deres fremstilling samt deres anvendelse til fremstilling af laegemidler - Google Patents
Aminoacyllabdaner, fremgangsmaade til deres fremstilling samt deres anvendelse til fremstilling af laegemidler Download PDFInfo
- Publication number
- DK167218B1 DK167218B1 DK578585A DK578585A DK167218B1 DK 167218 B1 DK167218 B1 DK 167218B1 DK 578585 A DK578585 A DK 578585A DK 578585 A DK578585 A DK 578585A DK 167218 B1 DK167218 B1 DK 167218B1
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- oil
- solution
- ethyl acetate
- lower alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68177984A | 1984-12-14 | 1984-12-14 | |
| US68177984 | 1984-12-14 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK578585D0 DK578585D0 (da) | 1985-12-13 |
| DK578585A DK578585A (da) | 1986-06-15 |
| DK167218B1 true DK167218B1 (da) | 1993-09-20 |
Family
ID=24736768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK578585A DK167218B1 (da) | 1984-12-14 | 1985-12-13 | Aminoacyllabdaner, fremgangsmaade til deres fremstilling samt deres anvendelse til fremstilling af laegemidler |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0191166B1 (pt) |
| JP (1) | JPS61145178A (pt) |
| KR (1) | KR900007625B1 (pt) |
| AR (1) | AR243877A1 (pt) |
| AT (1) | ATE60767T1 (pt) |
| AU (2) | AU577912B2 (pt) |
| CA (1) | CA1307529C (pt) |
| DE (1) | DE3581725D1 (pt) |
| DK (1) | DK167218B1 (pt) |
| ES (1) | ES8703460A1 (pt) |
| FI (1) | FI87208C (pt) |
| GR (1) | GR852981B (pt) |
| HU (1) | HU201043B (pt) |
| IE (1) | IE58698B1 (pt) |
| NO (1) | NO171064C (pt) |
| NZ (1) | NZ214532A (pt) |
| PH (1) | PH24599A (pt) |
| PT (1) | PT81659B (pt) |
| ZA (1) | ZA859556B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3678736D1 (de) * | 1985-03-01 | 1991-05-23 | Hoechst Roussel Pharma | Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel. |
| IN163242B (pt) * | 1985-05-03 | 1988-08-27 | Hoechst India | |
| JPS6310783A (ja) * | 1985-11-15 | 1988-01-18 | Nippon Kayaku Co Ltd | 新規フオルスコリン誘導体 |
| AU591196B2 (en) * | 1985-11-15 | 1989-11-30 | Nippon Kayaku Kabushiki Kaisha | Novel forskolin derivatives |
| US4734513A (en) * | 1986-03-31 | 1988-03-29 | Hoechst-Roussel Pharmaceuticals Inc. | Method of synthesizing forskolin from 9-deoxyforskolin |
| US4740522A (en) * | 1986-08-28 | 1988-04-26 | Hoechst-Roussel Pharmaceuticals Inc. | Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure |
| US5247097A (en) * | 1986-08-28 | 1993-09-21 | Hoechst-Roussel Pharmaceuticals Incorporated | Oxolabdanes |
| US5646175A (en) * | 1987-12-28 | 1997-07-08 | Hoechst Marion Roussel, Inc. | Carbamoyloxylabdane compounds |
| FI875699A (fi) * | 1986-12-29 | 1988-06-30 | Hoechst Roussel Pharma | Nya karbamoyloxilabdaner, mellanprodukter och foerfaranden foer deras framstaellning samt deras anvaendning saosom laekemedel. |
| US4920146A (en) * | 1986-12-29 | 1990-04-24 | Hoechst Roussel Pharmaceuticals Inc. | Carbamoyloxylabdane compounds useful in reducing intraocular pressure |
| US5302730A (en) * | 1987-06-29 | 1994-04-12 | Nippon Kayaku Kk | Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives |
| US4916204A (en) * | 1987-07-31 | 1990-04-10 | Massachusetts Institute Of Technology | Pure polyanhydride from dicarboxylic acid and coupling agent |
| US4902696A (en) * | 1987-10-08 | 1990-02-20 | Hoechst-Roussel Pharmaceuticals, Inc. | Synergistic intraocular pressure lowering combinations |
| US5846992A (en) * | 1987-10-08 | 1998-12-08 | Hoechst Marion Roussel, Inc. | Synergistic intraocular pressure lowering combinations |
| US4883793A (en) * | 1988-05-09 | 1989-11-28 | Hoechst-Roussel Pharmaceuticals Inc. | Hydrazinocarbonyloxylabdanes for treating cardiac failure |
| US5051132A (en) * | 1989-06-15 | 1991-09-24 | Nippon Kayaku Kabushiki Kaisha | Lyophilized preparation of 6-(3-dimethylaminopropionyl)forskolin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2654796A1 (de) * | 1976-12-03 | 1978-06-08 | Hoechst Ag | Polyoxygenierte labdan-derivate |
| IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
| DE3678736D1 (de) * | 1985-03-01 | 1991-05-23 | Hoechst Roussel Pharma | Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel. |
-
1985
- 1985-12-04 EP EP85115383A patent/EP0191166B1/en not_active Expired - Lifetime
- 1985-12-04 AT AT85115383T patent/ATE60767T1/de not_active IP Right Cessation
- 1985-12-04 DE DE8585115383T patent/DE3581725D1/de not_active Expired - Fee Related
- 1985-12-11 HU HU854740A patent/HU201043B/hu not_active IP Right Cessation
- 1985-12-12 PT PT81659A patent/PT81659B/pt not_active IP Right Cessation
- 1985-12-12 ES ES549860A patent/ES8703460A1/es not_active Expired
- 1985-12-12 PH PH33164A patent/PH24599A/en unknown
- 1985-12-12 FI FI854919A patent/FI87208C/fi not_active IP Right Cessation
- 1985-12-12 AR AR85302563A patent/AR243877A1/es active
- 1985-12-12 GR GR852981A patent/GR852981B/el unknown
- 1985-12-12 NZ NZ214532A patent/NZ214532A/xx unknown
- 1985-12-13 DK DK578585A patent/DK167218B1/da not_active IP Right Cessation
- 1985-12-13 KR KR1019850009388A patent/KR900007625B1/ko not_active IP Right Cessation
- 1985-12-13 IE IE316085A patent/IE58698B1/en not_active IP Right Cessation
- 1985-12-13 NO NO855026A patent/NO171064C/no unknown
- 1985-12-13 AU AU51316/85A patent/AU577912B2/en not_active Ceased
- 1985-12-13 ZA ZA859556A patent/ZA859556B/xx unknown
- 1985-12-13 JP JP60279417A patent/JPS61145178A/ja active Pending
- 1985-12-13 CA CA000497652A patent/CA1307529C/en not_active Expired - Lifetime
-
1989
- 1989-07-14 AU AU38132/89A patent/AU620421B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0191166A2 (en) | 1986-08-20 |
| PT81659A (en) | 1986-01-01 |
| PT81659B (pt) | 1988-04-21 |
| PH24599A (en) | 1990-08-17 |
| DK578585D0 (da) | 1985-12-13 |
| KR860004915A (ko) | 1986-07-16 |
| EP0191166A3 (en) | 1988-03-02 |
| AU5131685A (en) | 1986-07-17 |
| NO171064B (no) | 1992-10-12 |
| FI854919A (fi) | 1986-06-15 |
| AU3813289A (en) | 1989-10-26 |
| HUT40636A (en) | 1987-01-28 |
| AU620421B2 (en) | 1992-02-20 |
| DE3581725D1 (de) | 1991-03-14 |
| EP0191166B1 (en) | 1991-02-06 |
| ES8703460A1 (es) | 1987-02-16 |
| AR243877A1 (es) | 1993-09-30 |
| ATE60767T1 (de) | 1991-02-15 |
| JPS61145178A (ja) | 1986-07-02 |
| KR900007625B1 (ko) | 1990-10-17 |
| ES549860A0 (es) | 1987-02-16 |
| FI87208B (fi) | 1992-08-31 |
| CA1307529C (en) | 1992-09-15 |
| DK578585A (da) | 1986-06-15 |
| GR852981B (pt) | 1986-04-08 |
| NO855026L (no) | 1986-06-16 |
| ZA859556B (en) | 1986-08-27 |
| NO171064C (no) | 1993-01-20 |
| NZ214532A (en) | 1989-05-29 |
| FI87208C (fi) | 1992-12-10 |
| FI854919A0 (fi) | 1985-12-12 |
| HU201043B (en) | 1990-09-28 |
| IE58698B1 (en) | 1993-11-03 |
| AU577912B2 (en) | 1988-10-06 |
| IE853160L (en) | 1986-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |