DK165757C - Biologisk ren kultur af mikroorganismen streptomyces roseosporus nrrl 15998 samt en fremgangsmaade til fremstilling af det antibiotisk virksomme a-21978c kompleks eller en eller flere af dettes faktorer co' c1' c2' c3' c4' og c5' under anvendelse af mikroorganismen - Google Patents

Biologisk ren kultur af mikroorganismen streptomyces roseosporus nrrl 15998 samt en fremgangsmaade til fremstilling af det antibiotisk virksomme a-21978c kompleks eller en eller flere af dettes faktorer co' c1' c2' c3' c4' og c5' under anvendelse af mikroorganismen

Info

Publication number
DK165757C
DK165757C DK148791A DK148791A DK165757C DK 165757 C DK165757 C DK 165757C DK 148791 A DK148791 A DK 148791A DK 148791 A DK148791 A DK 148791A DK 165757 C DK165757 C DK 165757C
Authority
DK
Denmark
Prior art keywords
factors
cero
biologically
culture
complex
Prior art date
Application number
DK148791A
Other languages
English (en)
Other versions
DK148791A (da
DK165757B (da
DK148791D0 (da
Inventor
Floyd Milton Huber
Richard Louis Pieper
Anthony Joseph Tietz
Tom Edward Eaton
Lynda Maxine Ford
Jr Otis Webster Godfrey
Mary Louise Braun Huber
Jr Milton Joseph Zmijewski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK148791A publication Critical patent/DK148791A/da
Publication of DK148791D0 publication Critical patent/DK148791D0/da
Publication of DK165757B publication Critical patent/DK165757B/da
Application granted granted Critical
Publication of DK165757C publication Critical patent/DK165757C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treating Waste Gases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
DK148791A 1984-10-09 1991-08-21 Biologisk ren kultur af mikroorganismen streptomyces roseosporus nrrl 15998 samt en fremgangsmaade til fremstilling af det antibiotisk virksomme a-21978c kompleks eller en eller flere af dettes faktorer co' c1' c2' c3' c4' og c5' under anvendelse af mikroorganismen DK165757C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65897984A 1984-10-09 1984-10-09
US65897984 1984-10-09

Publications (4)

Publication Number Publication Date
DK148791A DK148791A (da) 1991-08-21
DK148791D0 DK148791D0 (da) 1991-08-21
DK165757B DK165757B (da) 1993-01-11
DK165757C true DK165757C (da) 1993-06-07

Family

ID=24643546

Family Applications (2)

Application Number Title Priority Date Filing Date
DK457585A DK165416C (da) 1984-10-09 1985-10-08 Fremgangsmaade til fremstilling af derivater af det antibiotisk virksomme cycliske peptid a-21978c
DK148791A DK165757C (da) 1984-10-09 1991-08-21 Biologisk ren kultur af mikroorganismen streptomyces roseosporus nrrl 15998 samt en fremgangsmaade til fremstilling af det antibiotisk virksomme a-21978c kompleks eller en eller flere af dettes faktorer co' c1' c2' c3' c4' og c5' under anvendelse af mikroorganismen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK457585A DK165416C (da) 1984-10-09 1985-10-08 Fremgangsmaade til fremstilling af derivater af det antibiotisk virksomme cycliske peptid a-21978c

Country Status (27)

Country Link
EP (1) EP0178152B1 (da)
JP (1) JPH0787796B2 (da)
KR (1) KR890000800B1 (da)
CN (2) CN1013120B (da)
AT (1) ATE67788T1 (da)
AU (2) AU4837785A (da)
BG (1) BG47040A3 (da)
CS (2) CS276983B6 (da)
CY (1) CY1633A (da)
DD (2) DD238068A5 (da)
DE (1) DE3584218D1 (da)
DK (2) DK165416C (da)
EG (1) EG17619A (da)
ES (2) ES8700862A1 (da)
FI (1) FI82075C (da)
GR (1) GR852432B (da)
HK (1) HK24292A (da)
HU (1) HU196845B (da)
IE (1) IE58655B1 (da)
IL (1) IL76608A (da)
NZ (1) NZ213731A (da)
PH (1) PH21217A (da)
PL (1) PL152359B1 (da)
PT (1) PT81265B (da)
SG (1) SG3292G (da)
SU (1) SU1452484A3 (da)
ZA (1) ZA857759B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294990A3 (en) * 1987-06-10 1990-05-09 Eli Lilly And Company Chromatographic purification process
US4930494A (en) * 1988-03-09 1990-06-05 Olympus Optical Co., Ltd. Apparatus for bending an insertion section of an endoscope using a shape memory alloy
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
DE3832362A1 (de) * 1988-09-23 1990-03-29 Sandoz Ag Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung
EP2295444A3 (en) 1999-12-15 2011-03-23 Cubist Pharmaceutical Inc. Lipopeptides as antibacterial agents
US7408025B2 (en) 1999-12-15 2008-08-05 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
US6696412B1 (en) * 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
CN102325787B (zh) 2008-12-22 2014-05-28 丘比斯特药物股份有限公司 治疗革兰氏阳性感染的新的抗菌剂
US8835382B2 (en) 2009-11-23 2014-09-16 Cubist Pharmaceuticals, Inc. Lipopeptide compositions and related methods
KR20140057414A (ko) * 2011-06-22 2014-05-12 바이옴 바이오사이언스 피브이티. 엘티디. 컨쥬게이트계 항진균 및 항세균 프로드러그
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
CN107964557B (zh) * 2018-01-17 2020-11-20 自然资源部第三海洋研究所 一种提高芽孢杆菌抗菌脂肽产量的发酵方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production

Also Published As

Publication number Publication date
DD238068A5 (de) 1986-08-06
DK165416C (da) 1993-04-05
EP0178152A3 (en) 1988-11-02
PL152359B1 (en) 1990-12-31
KR890000800B1 (ko) 1989-04-07
JPS6192588A (ja) 1986-05-10
FI853910L (fi) 1986-04-10
ES8800362A1 (es) 1987-11-01
FI82075C (fi) 1991-01-10
HU196845B (en) 1989-01-30
ES8700862A1 (es) 1986-11-16
CS276978B6 (en) 1992-11-18
EP0178152B1 (en) 1991-09-25
CN1013120B (zh) 1991-07-10
FI82075B (fi) 1990-09-28
PH21217A (en) 1987-08-21
DK148791A (da) 1991-08-21
AU4837785A (en) 1986-04-17
IE58655B1 (en) 1993-11-03
NZ213731A (en) 1988-04-29
DK165757B (da) 1993-01-11
KR860003335A (ko) 1986-05-23
IL76608A0 (en) 1986-02-28
DE3584218D1 (de) 1991-10-31
PT81265B (pt) 1988-02-17
SU1452484A3 (ru) 1989-01-15
DK457585A (da) 1986-04-10
CY1633A (en) 1992-11-06
GR852432B (da) 1986-02-10
CN85107552A (zh) 1987-05-20
DK457585D0 (da) 1985-10-08
DK165416B (da) 1992-11-23
ATE67788T1 (de) 1991-10-15
AU634766B2 (en) 1993-03-04
ES553603A0 (es) 1987-11-01
PL255683A1 (en) 1986-07-29
ZA857759B (en) 1987-05-27
CS276983B6 (en) 1992-11-18
DD247023A5 (de) 1987-06-24
ES547689A0 (es) 1986-11-16
BG47040A3 (en) 1990-04-16
CS719885A3 (en) 1992-03-18
EG17619A (en) 1991-03-30
CS819286A3 (en) 1992-03-18
IL76608A (en) 1991-03-10
CN1051200A (zh) 1991-05-08
EP0178152A2 (en) 1986-04-16
AU5375290A (en) 1990-11-01
IE852466L (en) 1986-04-09
HK24292A (en) 1992-04-10
SG3292G (en) 1992-03-20
JPH0787796B2 (ja) 1995-09-27
PT81265A (en) 1985-11-01
HUT39782A (en) 1986-10-29
FI853910A0 (fi) 1985-10-08
DK148791D0 (da) 1991-08-21

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