DK1654284T3 - Fremgangsmåde til fremstilling af en alfa-1-antitrypsinoplösning - Google Patents

Fremgangsmåde til fremstilling af en alfa-1-antitrypsinoplösning

Info

Publication number
DK1654284T3
DK1654284T3 DK04764046T DK04764046T DK1654284T3 DK 1654284 T3 DK1654284 T3 DK 1654284T3 DK 04764046 T DK04764046 T DK 04764046T DK 04764046 T DK04764046 T DK 04764046T DK 1654284 T3 DK1654284 T3 DK 1654284T3
Authority
DK
Denmark
Prior art keywords
a1at
preparing
alpha
detergents
antitrypsin solution
Prior art date
Application number
DK04764046T
Other languages
English (en)
Inventor
Petra Schulz
Juergen Roemisch
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Application granted granted Critical
Publication of DK1654284T3 publication Critical patent/DK1654284T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
DK04764046T 2003-08-12 2004-08-12 Fremgangsmåde til fremstilling af en alfa-1-antitrypsinoplösning DK1654284T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49409703P 2003-08-12 2003-08-12
PCT/EP2004/009043 WO2005014648A1 (en) 2003-08-12 2004-08-12 Process for preparing an alpha-1-antitrypsin solution

Publications (1)

Publication Number Publication Date
DK1654284T3 true DK1654284T3 (da) 2009-07-20

Family

ID=34135316

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04764046T DK1654284T3 (da) 2003-08-12 2004-08-12 Fremgangsmåde til fremstilling af en alfa-1-antitrypsinoplösning

Country Status (22)

Country Link
US (1) US20060194300A1 (da)
EP (1) EP1654284B1 (da)
JP (1) JP4668904B2 (da)
KR (1) KR20060070543A (da)
CN (1) CN1867582B (da)
AT (1) ATE428730T1 (da)
AU (1) AU2004262578B2 (da)
BR (1) BRPI0412835A (da)
CA (1) CA2534900A1 (da)
DE (1) DE602004020632D1 (da)
DK (1) DK1654284T3 (da)
ES (1) ES2324168T3 (da)
IL (1) IL172868A0 (da)
NO (1) NO20060109L (da)
PL (1) PL1654284T3 (da)
PT (1) PT1654284E (da)
RS (1) RS20060077A (da)
RU (1) RU2370500C2 (da)
SI (1) SI1654284T1 (da)
UA (1) UA86775C2 (da)
WO (1) WO2005014648A1 (da)
ZA (1) ZA200601206B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1664123T2 (sl) * 2003-09-22 2012-03-30 Kamada Ltd Priprava inhibitorja alfa proteinaze v velikem merilu in njegova uporaba
ES2246695B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
ES2246694B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Nanoparticulas pegiladas.
CN100354301C (zh) * 2005-10-13 2007-12-12 南京工业大学 化学合成多肽的新型大规模分离制备技术
WO2009059082A2 (en) 2007-11-02 2009-05-07 Talecris Biotherapeutics, Inc. Method, composition, and article of manufacture for providing alpha-1 antitrypsin
CN102127165B (zh) * 2010-01-15 2013-09-04 上海莱士血液制品股份有限公司 一种从血浆组分四沉淀中制备高纯ApoA-I的生产工艺
CN102731642B (zh) * 2011-04-14 2014-01-29 上海莱士血液制品股份有限公司 从人血浆组分四沉淀制备高纯Apoa-I的生产工艺
US9353165B2 (en) * 2012-07-25 2016-05-31 Grifols, S.A. Purification of cell culture derived alpha1 protease inhibitor
AU2013205138B2 (en) 2012-08-09 2015-06-25 Grifols, S.A. Caprylate Viral Deactivation
EP3628675A1 (en) 2015-06-26 2020-04-01 Ferring B.V. Methods of purification and/or viral inactivation
CN108779144B (zh) * 2016-02-03 2022-06-14 普莱泽玛科技有限公司 从血液原料中提取蛋白质的方法
CN111991571B (zh) * 2020-08-12 2022-04-05 湖州师范学院 一种柱上低pH病毒灭活的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS584728A (ja) * 1981-05-01 1983-01-11 メデイカル・リサ−チ・インステイチユ−ト・オブ・サンフランシスコ・コ−ポレ−シヨン α−１−抗トリプシンの精製
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
US4629567A (en) * 1986-03-07 1986-12-16 Smithkline-Rit Alpha-1-antiprotease purification
EP0288841B1 (en) * 1987-04-27 1992-12-30 Miles Inc. Method of preparing highly purified alpha-1-proteinase inhibitor
KR920005689B1 (ko) * 1989-12-21 1992-07-13 국제약품공업주식회사 혈청으로부터 알파-1-안티트립신의 분리 정제 및 혈중 알파-1-안티트립신 양의 검정키트
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
SE9301582D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Purification of plasma proteins
DE4407837C1 (de) * 1994-03-09 1995-08-17 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem alpha¶1¶-Antitrypsin mittels Anionenaustauscher-Chromatographie
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
JP4105249B2 (ja) * 1996-08-09 2008-06-25 財団法人化学及血清療法研究所 α２プラスミンインヒビターの製造方法
AT407114B (de) * 1997-06-10 2000-12-27 Immuno Ag Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
CN1867582A (zh) 2006-11-22
CA2534900A1 (en) 2005-02-17
KR20060070543A (ko) 2006-06-23
JP4668904B2 (ja) 2011-04-13
NO20060109L (no) 2006-02-15
ZA200601206B (en) 2007-05-30
BRPI0412835A (pt) 2006-09-26
EP1654284A1 (en) 2006-05-10
PT1654284E (pt) 2009-07-06
IL172868A0 (en) 2006-06-11
CN1867582B (zh) 2010-06-16
US20060194300A1 (en) 2006-08-31
SI1654284T1 (sl) 2009-10-31
ES2324168T3 (es) 2009-07-31
RU2006107533A (ru) 2006-07-27
UA86775C2 (ru) 2009-05-25
ATE428730T1 (de) 2009-05-15
AU2004262578B2 (en) 2010-05-06
JP2007523883A (ja) 2007-08-23
AU2004262578A1 (en) 2005-02-17
RS20060077A (en) 2008-08-07
RU2370500C2 (ru) 2009-10-20
PL1654284T3 (pl) 2009-09-30
DE602004020632D1 (de) 2009-05-28
WO2005014648A1 (en) 2005-02-17
EP1654284B1 (en) 2009-04-15

Similar Documents

Publication Publication Date Title
NO20060109L (no) Fremgangsmate for fremstilling av alfa- 1antitrypsinlosning
DK1475101T3 (da) Antistof-holdige farmaceutiske opløsninger
NZ593214A (en) Compounds and Processes for preparing serine protease inhibitors
WO2004037784A3 (en) Pyrrolidones with anti-hiv activity
BRPI0415883A (pt) compostos e composições de nucleosìdeo para o tratamento de infecções virais
HN1998000143A (es) Tetrahidronaftalenos substituidos y compuestos analogos.
ATE373005T1 (de) Thienopyrrole als antivirale mittel
DE60307268D1 (de) Pestizide pyridincarbonsäureamidderivate
ATE368645T1 (de) Aminosäurederivate als hiv-protease-inhibitoren
ATE315558T1 (de) Verbindungen mit cytochrom p450ra1 hemmenden aktivität
SE0300850D0 (sv) Chemical compounds
PE103799A1 (es) Procedimiento de purificacion de mesilato de alatrofloxacino
HK1053826A1 (en) Propenecarboxylic acid amidoxime derivatives, a process for the preparation thereof, and pharmaceutical compositions containing the same.
SE0200843D0 (sv) Chemical compounds
ATE272436T1 (de) Mikrofiltration unter verwendung von aktivkohle
EA200200502A1 (ru) Способ введения ингибитора фосфодиэстеразы 4
WO2004037853A3 (en) Quinolones with anti-hiv activity
ATE395057T1 (de) Gebrauchsfertige oxaliplatin-lösungen
ATE358621T1 (de) Sequenzgestell
NO20053592L (no) Vann opploslige fenylpyridazinderivater og medikamenter inneholdende disse.
SE9904289D0 (sv) Method and camposition for the treatment of adenovairal ocular infections
TWI265151B (en) Method of purifying niobium compound and/or tantalum compound
AU2003302275A1 (en) Bicyclic carbohydrate compounds useful in the treatment of infections caused by flaviviridae sp., such as hepatitis c and bovine viral diarrhea viruses
BR0313076A (pt) Sal de ácido orgânico de amlodipina
DK1214315T3 (da) 1,4-Dihydropyridin-5-carboxylsyreesterderivater og fremgangsmåde til fremstilling af samme