DK164704C - 3,6-disubstituerede triazolo-oe3,4-aaa-ftalazinderivater, fremgangsmaade til fremstilling deraf, udgangsforbindelse til anvendelse i fremgangsmaaden samt anvendelse af og farmaceutisk praeparat indeholdende forbindelserne - Google Patents

3,6-disubstituerede triazolo-oe3,4-aaa-ftalazinderivater, fremgangsmaade til fremstilling deraf, udgangsforbindelse til anvendelse i fremgangsmaaden samt anvendelse af og farmaceutisk praeparat indeholdende forbindelserne

Info

Publication number
DK164704C
DK164704C DK331884A DK331884A DK164704C DK 164704 C DK164704 C DK 164704C DK 331884 A DK331884 A DK 331884A DK 331884 A DK331884 A DK 331884A DK 164704 C DK164704 C DK 164704C
Authority
DK
Denmark
Prior art keywords
preparation
pharmaceutical preparation
triazolo
disubstituted
derivatives
Prior art date
Application number
DK331884A
Other languages
English (en)
Other versions
DK331884D0 (da
DK331884A (da
DK164704B (da
Inventor
Emilio Occelli
Giorgio Tarzia
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of DK331884D0 publication Critical patent/DK331884D0/da
Publication of DK331884A publication Critical patent/DK331884A/da
Publication of DK164704B publication Critical patent/DK164704B/da
Application granted granted Critical
Publication of DK164704C publication Critical patent/DK164704C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK331884A 1983-07-12 1984-07-06 3,6-disubstituerede triazolo-oe3,4-aaa-ftalazinderivater, fremgangsmaade til fremstilling deraf, udgangsforbindelse til anvendelse i fremgangsmaaden samt anvendelse af og farmaceutisk praeparat indeholdende forbindelserne DK164704C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2201483 1983-07-12
IT22014/83A IT1194310B (it) 1983-07-12 1983-07-12 Derivati triazolo (3,4-a) ftalazinici 3,6-disostituiti

Publications (4)

Publication Number Publication Date
DK331884D0 DK331884D0 (da) 1984-07-06
DK331884A DK331884A (da) 1985-01-13
DK164704B DK164704B (da) 1992-08-03
DK164704C true DK164704C (da) 1992-12-21

Family

ID=11190206

Family Applications (1)

Application Number Title Priority Date Filing Date
DK331884A DK164704C (da) 1983-07-12 1984-07-06 3,6-disubstituerede triazolo-oe3,4-aaa-ftalazinderivater, fremgangsmaade til fremstilling deraf, udgangsforbindelse til anvendelse i fremgangsmaaden samt anvendelse af og farmaceutisk praeparat indeholdende forbindelserne

Country Status (9)

Country Link
US (1) US4783461A (da)
EP (1) EP0134946B1 (da)
JP (1) JPS6056982A (da)
AT (1) ATE28874T1 (da)
AU (1) AU560726B2 (da)
CA (1) CA1234114A (da)
DE (1) DE3465309D1 (da)
DK (1) DK164704C (da)
IT (1) IT1194310B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0600527A2 (en) 1996-07-25 2006-11-28 Merck Sharp & Dohme Substituted triazolo-pyridazine derivatives as ligands for gaba receptors, process for their preparation and pharmaceutical compositions containing them
EP0915877A1 (en) * 1996-07-25 1999-05-19 MERCK SHARP & DOHME LTD. SUBSTITUTED TRIAZOLO PYRIDAZINE DERIVATIVES AS INVERSE AGONISTS OF THE GABA A?$g(a)5 RECEPTOR SUBTYPE
CA2288789C (en) 1997-05-08 2009-07-21 Merck Sharp & Dohme Limited Substituted 1,2,4-triazolo[3,4-a]phthalazine derivatives as gaba alpha 5 ligands
GB9715977D0 (en) 1997-07-29 1997-10-01 Merck Sharp & Dohme Therapeutic agents
GB9726702D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9726701D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9726699D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9723999D0 (en) 1997-11-13 1998-01-14 Merck Sharp & Dohme Therapeutic use
US6110915A (en) * 1997-12-18 2000-08-29 Merck & Co., Inc. Antiemetic use of triazolo-pyridazine derivatives
EP1047697A1 (en) 1998-01-14 2000-11-02 MERCK SHARP & DOHME LTD. Triazolo-pyridazine derivatives as ligands for gaba receptors
GB9801202D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
IL136442A0 (en) 1998-01-21 2001-06-14 Merck Sharp & Dohme Triazolo-pyridazine derivatives as ligands for gaba receptors
GB9801234D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801210D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801208D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801397D0 (en) 1998-01-22 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801538D0 (en) 1998-01-23 1998-03-25 Merck Sharp & Dohme Pharmaceutical product
CZ291302B6 (cs) 1998-02-25 2003-01-15 Merck Sharp & Dohme Limited Substituovaný 1,2,4-triazolo[3,4-a]ftalazinový derivát
IT1303272B1 (it) * 1998-10-29 2000-11-06 Zambon Spa Derivati triciclici inibitori della fosfodiesterasi 4
JP2002529468A (ja) 1998-11-12 2002-09-10 メルク エンド カムパニー インコーポレーテッド ＧＡＢＡ−Ａα−５逆活性薬の治療性多形およびそのパモエート組成物
GB9824897D0 (en) 1998-11-12 1999-01-06 Merck Sharp & Dohme Therapeutic compounds
MXPA02004735A (es) * 1999-11-12 2003-01-28 Orive Javier Uhthoff Compuestos heteroaromaticos, biciclicos y triciclicos.
GB0028583D0 (en) 2000-11-23 2001-01-10 Merck Sharp & Dohme Therapeutic compounds
KR20070095986A (ko) * 2005-01-05 2007-10-01 니코메드 게엠베하 Ｐｄｅ2 억제제로서의 트리아졸로프탈라진
CA2591991C (en) * 2005-01-05 2013-11-19 Altana Pharma Ag Triazolophthalazines
CA2750458C (en) 2009-01-29 2017-10-24 Basf Se Absorbent comprising amino acids and acidic promoter for removing acidic gases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2484029A (en) * 1945-12-21 1949-10-11 Ciba Pharm Prod Inc Hydrazine derivatives of pyridazine compounds
GB629177A (en) * 1945-12-21 1949-09-14 Ciba Ltd Manufacture of new hydrazine compounds and derivatives thereof
US3711481A (en) * 1970-04-24 1973-01-16 G Hardtmann 6-aryl-imidazo(2,1-a)phthalazines
US3694442A (en) * 1970-07-28 1972-09-26 William J Houlihan SUBSTITUTED TETRAHYDRO-1H-PYRAZOLO{8 1,2-b{9 PHTHALAZINES
US3704300A (en) * 1971-04-09 1972-11-28 Sandoz Ag Imidazo(2,1-a)phthalazines
JPS603080B2 (ja) * 1976-08-10 1985-01-25 三菱化学株式会社 Ｓ―トリアゾロ〔３，４ ―α〕〔５，６，７，８〕テトラヒドロ フタラジン類
GR70309B (da) * 1979-10-29 1982-09-08 Dow Chemical Co
FI81350C (fi) * 1982-01-18 1990-10-10 Lepetit Spa Analogfoerfarande foer framstaellning av nya, farmakologiskt aktiva 6-substituerade s-triatsolo/3,4-a/ ftalazinderivat.
US4485106A (en) * 1982-07-12 1984-11-27 The Dow Chemical Company Substituted tetrahydrotetrazolo[5,1-a]phthalazines
US4391807A (en) * 1982-07-12 1983-07-05 The Dow Chemical Company 6-Substituted tetrahydroimidazo[2,1-a]phthalazines and use as bronchodilators
US4487930A (en) * 1982-09-07 1984-12-11 The Dow Chemical Company 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines

Also Published As

Publication number Publication date
JPS6056982A (ja) 1985-04-02
DK331884D0 (da) 1984-07-06
EP0134946B1 (en) 1987-08-12
ATE28874T1 (de) 1987-08-15
AU560726B2 (en) 1987-04-16
AU3022484A (en) 1985-01-17
DK331884A (da) 1985-01-13
DE3465309D1 (de) 1987-09-17
CA1234114A (en) 1988-03-15
DK164704B (da) 1992-08-03
EP0134946A1 (en) 1985-03-27
IT8322014A0 (it) 1983-07-12
JPH051267B2 (da) 1993-01-07
IT1194310B (it) 1988-09-14
US4783461A (en) 1988-11-08

Similar Documents

Publication Publication Date Title
DK164704C (da) 3,6-disubstituerede triazolo-oe3,4-aaa-ftalazinderivater, fremgangsmaade til fremstilling deraf, udgangsforbindelse til anvendelse i fremgangsmaaden samt anvendelse af og farmaceutisk praeparat indeholdende forbindelserne
DK422583D0 (da) Fremgangsmade til fremstilling af diazobicyclo-(3,3,1)-nonaner
ES8703736A1 (es) Procedimiento de preparacion de un a composicion cosmetica antisolar
DE3066296D1 (en) 3,4-diarylisoxazol-5-acetic acid compounds, process for preparing the same, and pharmaceuticals containing the same
DK509382A (da) Fremgangsmaade til fremstilling af antifibrinolytisk virksomme forbindelser
DK148183A (da) Fremgangsmaade til fremstilling af imidazolylphenyl-tetrahydropyridaziner
CS621987A2 (en) Coating composition
ES528452A0 (es) Procedimiento de preparacion de nuevos derivados dietilaminoalcoxibenzoles y de sus sales de adicion acidas y amonicas cuaternarias
DK532679A (da) Fremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo (4,1,0)hepten-(2)-on-(5).
ES8703832A1 (es) Procedimiento para preparar derivados de difluorociclopropano
ES8103081A1 (es) Procedimiento para la obtencion de diazatriciclos
EP0481370A3 (en) Use of phosphonic acid diglycidylesters as cross-linking agent in hydrogels
DK159769C (da) Resorcinderivater og analogifremgangsmaade til fremstilling heraf, farmaceutiske praeparater indeholdende disse, samt fremgangsmaade til fremstilling af disse farmaceutiske praeparater
DE3269505D1 (en) Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them
DK159649C (da) 4-hydroxy-alfa-benzhydrolderivater, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende disse, samt fremgangsmaade til fremstilling af disse farmaceutiske praeparater
NO842825L (no) Pyridazino(4,3-c) isokinolinderivater og fremgangsmaate for deres fremstilling
ATE19472T1 (de) Verwendung von 5-phenyl-1,4-benzodoazepinen zur herstellung von analgetisch wirksamen pharmazeutischen zubereitungen.
ES8306100A1 (es) "procedimiento para la preparacion de derivados de formamidina".
ES515201A0 (es) "procedimiento para la fabricacion de derivados n- susbtituidos de la tetrahidroisftalimida".
DK87483D0 (da) Fremgangsmade til fremstilling af vinyloge carboxamider
DK80286A (da) Hidtil ukendte benzoylurinstofforbindelser, fremgangsmaade til fremstilling heraf samt antitumorkompositioner indeholdende samme
EP0093049A3 (en) Dithiino (1,4) (2,3-c) pyrrole derivatives, their preparation and pharmaceutical compositions containing them
GB2111997A (en) Composition and method for inhibiting terminal deoxyribonucleotidyl transferase activity

Legal Events

Date Code Title Description
PBP Patent lapsed