DK139974B - Process for the preparation of 8,14-dihydrothebain or dihydrocodeinone from thebain by reduction using diimine formed as an unstable intermediate as a reducing agent. - Google Patents

Process for the preparation of 8,14-dihydrothebain or dihydrocodeinone from thebain by reduction using diimine formed as an unstable intermediate as a reducing agent.

Info

Publication number: DK139974B
Authority: DK; Denmark
Prior art keywords: dihydrothebain; thebain; dihydrocodeinone; reduction; preparation
Prior art date: 1970-12-11

Application number

DK603371AA

Other languages

Danish (da)

Other versions

DK139974C (en

Inventor

Edward Leon Grew

Alastair Agnew Robertson

Original Assignee

Macfarlan Smith Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-12-11

Filing date

1971-12-09

Publication date

1979-05-28

1971-12-09 Application filed by Macfarlan Smith Ltd filed Critical Macfarlan Smith Ltd

1979-05-28 Publication of DK139974B publication Critical patent/DK139974B/en

1979-12-10 Application granted granted Critical

1979-12-10 Publication of DK139974C publication Critical patent/DK139974C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK603371AA 1970-12-11 1971-12-09 Process for the preparation of 8,14-dihydrothebain or dihydrocodeinone from thebain by reduction using diimine formed as an unstable intermediate as a reducing agent. DK139974B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB5892670		1970-12-11

Publications (2)

Publication Number	Publication Date
DK139974B true DK139974B (en)	1979-05-28
DK139974C DK139974C (en)	1979-12-10

Family

ID=10482707

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK603371AA DK139974B (en)	1970-12-11	1971-12-09	Process for the preparation of 8,14-dihydrothebain or dihydrocodeinone from thebain by reduction using diimine formed as an unstable intermediate as a reducing agent.

Country Status (17)

Country	Link
US (1)	US3812132A (en)
JP (1)	JPS5511678B1 (en)
AU (1)	AU459401B2 (en)
BE (1)	BE776304A (en)
CA (1)	CA958412A (en)
CH (1)	CH556340A (en)
CS (1)	CS176251B2 (en)
DE (1)	DE2159348A1 (en)
DK (1)	DK139974B (en)
FR (1)	FR2117924B1 (en)
GB (1)	GB1317210A (en)
HU (1)	HU164465B (en)
IL (1)	IL38268A (en)
NL (1)	NL175622C (en)
PL (1)	PL81441B1 (en)
SE (1)	SE388422B (en)
YU (1)	YU39064B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS59142770A (en) *	1983-02-02	1984-08-16	Trio Kenwood Corp	Driving mechanism of cassette tape recorder
GB2429206A (en) *	2004-07-09	2007-02-21	Tasmanian Alkaloids Pty Ltd	Process for the synthesis of hydromorphone
EP2073636B1 (en)	2006-10-17	2012-09-05	Penick Corporation	Process for preparing oxymorphone
US20080125592A1 (en) *	2006-10-17	2008-05-29	Penick Corporation	Process for preparing oxymorphone, naltrexone, and buprenorphine
CA2674915C (en)	2006-10-17	2015-06-30	Penick Corporation	Process for preparing oxymorphone
GB0624880D0 (en) *	2006-12-14	2007-01-24	Johnson Matthey Plc	Improved method for making analgesics
US9131649B2 (en) *	2008-03-07	2015-09-15	Tasmanian Alkaloids Pty. Ltd	Papaver somniferum strain with high concentration of thebaine
US8541647B2 (en) *	2008-05-29	2013-09-24	Tasmania Alkaloids Pty, Ltd.	Papaver somniferum with high concentration of codeine
ES2560787T3 (en) *	2009-09-22	2016-02-22	Mallinckrodt Llc	Methods for producing hydrocodone, hydromorphone or a derivative thereof
CA2936749C (en)	2010-06-11	2019-07-09	Joshua R. Giguere	Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
EP2580218B1 (en)	2010-06-11	2015-02-25	Rhodes Technologies	Process for n-dealkylation of tertiary amines
CN105452253A (en)	2013-08-02	2016-03-30	庄信万丰股份有限公司	Process for preparation of oxymorphone
US9273060B2 (en)	2014-03-05	2016-03-01	Johnson Matthey Public Limited Company	Processes for making hydrocodone, hydromorphone and their derivatives
WO2015134003A1 (en)	2014-03-05	2015-09-11	Johnson Matthey Public Limited Company	Processes for making hydrocodone, hydromorphone and their derivatives
US10155771B2 (en)	2015-11-04	2018-12-18	Noramco, Inc.	Selective reduction of morphinan alkaloids

1970
- 1970-12-11 GB GB5892670A patent/GB1317210A/en not_active Expired
1971
- 1971-11-24 PL PL1971151754A patent/PL81441B1/pl unknown
- 1971-11-30 CA CA128,915A patent/CA958412A/en not_active Expired
- 1971-11-30 DE DE19712159348 patent/DE2159348A1/en not_active Withdrawn
- 1971-11-30 IL IL38268A patent/IL38268A/en unknown
- 1971-12-02 US US00204298A patent/US3812132A/en not_active Expired - Lifetime
- 1971-12-03 AU AU36469/71A patent/AU459401B2/en not_active Expired
- 1971-12-06 BE BE776304A patent/BE776304A/en not_active IP Right Cessation
- 1971-12-07 JP JP9899371A patent/JPS5511678B1/ja active Pending
- 1971-12-07 FR FR7143867A patent/FR2117924B1/fr not_active Expired
- 1971-12-09 CS CS8571A patent/CS176251B2/cs unknown
- 1971-12-09 DK DK603371AA patent/DK139974B/en unknown
- 1971-12-09 YU YU03086/71A patent/YU39064B/en unknown
- 1971-12-10 HU HUMA2294A patent/HU164465B/hu unknown
- 1971-12-10 CH CH1811571A patent/CH556340A/en not_active IP Right Cessation
- 1971-12-10 SE SE7115886A patent/SE388422B/en unknown
- 1971-12-13 NL NLAANVRAGE7117082,A patent/NL175622C/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU164465B (en)	1974-02-28
BE776304A (en)	1972-06-06
AU459401B2 (en)	1975-03-27
IL38268A0 (en)	1972-01-27
IL38268A (en)	1974-11-29
FR2117924A1 (en)	1972-07-28
FR2117924B1 (en)	1975-02-07
NL7117082A (en)	1972-06-13
YU308671A (en)	1982-06-30
YU39064B (en)	1984-04-30
DK139974C (en)	1979-12-10
SE388422B (en)	1976-10-04
CH556340A (en)	1974-11-29
PL81441B1 (en)	1975-08-30
JPS5511678B1 (en)	1980-03-26
CS176251B2 (en)	1977-06-30
US3812132A (en)	1974-05-21
GB1317210A (en)	1973-05-16
NL175622B (en)	1984-07-02
DE2159348A1 (en)	1972-06-15
NL175622C (en)	1984-12-03
AU3646971A (en)	1973-06-07
CA958412A (en)	1974-11-26

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