DK1392328T3 - Medikament til beskyttelse i radioterapi - Google Patents
Medikament til beskyttelse i radioterapiInfo
- Publication number
- DK1392328T3 DK1392328T3 DK02717355T DK02717355T DK1392328T3 DK 1392328 T3 DK1392328 T3 DK 1392328T3 DK 02717355 T DK02717355 T DK 02717355T DK 02717355 T DK02717355 T DK 02717355T DK 1392328 T3 DK1392328 T3 DK 1392328T3
- Authority
- DK
- Denmark
- Prior art keywords
- radiotherapy
- medication
- protection
- relates
- protectant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26239001P | 2001-01-19 | 2001-01-19 | |
PCT/US2002/001507 WO2002060383A2 (en) | 2001-01-19 | 2002-01-22 | Cancer therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1392328T3 true DK1392328T3 (da) | 2009-11-09 |
Family
ID=22997293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02717355T DK1392328T3 (da) | 2001-01-19 | 2002-01-22 | Medikament til beskyttelse i radioterapi |
Country Status (10)
Country | Link |
---|---|
US (2) | US20030050297A1 (ja) |
EP (1) | EP1392328B1 (ja) |
JP (3) | JP2004520380A (ja) |
AT (1) | ATE439134T1 (ja) |
AU (1) | AU2002248366B2 (ja) |
CA (1) | CA2436245C (ja) |
DE (1) | DE60233317D1 (ja) |
DK (1) | DK1392328T3 (ja) |
ES (1) | ES2330728T3 (ja) |
WO (1) | WO2002060383A2 (ja) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030032634A1 (en) | 2001-06-01 | 2003-02-13 | Piganelli Jon D. | Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance |
ATE312103T1 (de) * | 1999-01-25 | 2005-12-15 | Nat Jewish Med & Res Center | Substituierte porphyrine und deren therapeutische verwendungen |
GB2397067B (en) * | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
FR2863892B1 (fr) * | 2003-12-18 | 2007-05-11 | Univ Paris Descartes | Utilisation de mimetiques de la superoxyde dismutase et de la glutathion reductase comme anti-cancereux |
US7807825B2 (en) | 2004-02-09 | 2010-10-05 | Duke University | Substituted porphyrins |
WO2005084665A1 (ja) * | 2004-03-04 | 2005-09-15 | Makoto Yuasa | 金属ポルフィリン錯体包埋ニオソーム、その製造法およびこれを利用する医薬 |
GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
HUE044234T2 (hu) | 2006-10-12 | 2019-10-28 | Galera Labs Llc | Eljárások szájnyálkahártya-gyulladás kezelésére |
US8987245B2 (en) | 2008-04-02 | 2015-03-24 | Jonathan R. Brestoff Parker | Composition and method for affecting obesity and related conditions |
US8598150B1 (en) | 2008-04-02 | 2013-12-03 | Jonathan R. Brestoff | Composition and method for affecting obesity and related conditions |
RU2506083C2 (ru) * | 2008-05-23 | 2014-02-10 | Нэшнл Джуиш Хелт | Способ лечения поражений, ассоциированных с воздействием алкилирующих веществ |
WO2010045220A1 (en) * | 2008-10-14 | 2010-04-22 | Edison Pharmaceuticals, Inc. | Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells |
ES2355784B1 (es) * | 2009-09-21 | 2012-02-03 | Universitat De Valencia | Complejos metalicos mimeticos de sod |
CN111467351A (zh) | 2011-09-26 | 2020-07-31 | 加莱拉实验室有限责任公司 | 用于治疗疾病的方法 |
WO2013130150A2 (en) | 2011-12-02 | 2013-09-06 | The Regents Of The University Of Colorado, A Body Corporate | Metalloporphyrin neurological treatments |
CN102617581B (zh) * | 2012-03-15 | 2013-11-06 | 中国药科大学 | 58Fe氯高铁血红素、其制备及其在药动学研究中的应用 |
JP6154231B2 (ja) * | 2013-07-22 | 2017-06-28 | 学校法人同志社 | 抗癌剤 |
CN108350009B (zh) | 2015-08-11 | 2021-07-09 | 加莱拉实验室有限责任公司 | 具有口服生物利用率的五氮杂大环状环络合物 |
WO2018187411A1 (en) * | 2017-04-04 | 2018-10-11 | Biomimetix Jv, Llc | Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure |
IL295620B2 (en) | 2017-04-13 | 2024-01-01 | Galera Labs Llc | Cancer immunotherapy combined with a macrocyclic ring pentase complex |
CA3076008A1 (en) | 2017-09-29 | 2019-04-04 | Duke University | Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same |
TWI669120B (zh) * | 2018-05-17 | 2019-08-21 | 國立交通大學 | 鎳超氧歧化酶擬態化合物用於製備癌症治療藥物的用途 |
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DE3464252D1 (en) | 1983-06-03 | 1987-07-23 | Hoffmann La Roche | Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation |
US4829984A (en) * | 1983-12-15 | 1989-05-16 | Gordon Robert T | Method for the improvement of transplantation techniques and for the preservation of tissue |
US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
US5087438A (en) * | 1984-07-03 | 1992-02-11 | Gordon Robert T | Method for affecting intracellular and extracellular electric and magnetic dipoles |
GB8429845D0 (en) * | 1984-11-26 | 1985-01-03 | Efamol Ltd | Porphyrins & cancer treatment |
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US4657902A (en) * | 1985-03-25 | 1987-04-14 | The Rockefeller University | Therapeutic use of tin mesoporphyrin |
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US5223538A (en) * | 1987-03-31 | 1993-06-29 | Duke University | Superoxide dismutase mimic |
US4892941A (en) * | 1987-04-17 | 1990-01-09 | Dolphin David H | Porphyrins |
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US5051337A (en) * | 1987-06-10 | 1991-09-24 | Director-General Of Agency Of Industrial Science And Technology | Optical recording material |
US5162519A (en) * | 1988-03-11 | 1992-11-10 | Efamol Holdings Plc | Porphyrins and cancer treatment |
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DE3809671A1 (de) | 1988-03-18 | 1989-09-28 | Schering Ag | Porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
US5284647A (en) * | 1988-03-18 | 1994-02-08 | Schering Aktiengesellschaft | Mesotetraphenylporphyrin complex compounds, process for their production and pharmaceutical agents containing them |
US5192788A (en) * | 1988-05-23 | 1993-03-09 | Georgia State University Foundation, Inc. | Porphyrin antiviral compositions |
US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
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US5010073A (en) * | 1989-10-05 | 1991-04-23 | The Rockefeller University | Use of liposomes as carriers for metalloporphyrins |
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US5202317A (en) | 1990-09-13 | 1993-04-13 | The Regents Of The University Of California | Synthetic drug molecules that mimic metalloenzymes |
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FR2676738B1 (fr) | 1991-05-22 | 1995-05-05 | Ir2M | Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante. |
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US5212300A (en) | 1991-09-12 | 1993-05-18 | Sun Company, Inc. (R&M) | Cyano- and polycyanometallo-porphyrins as catalysts for alkane oxidation |
US6011146A (en) * | 1991-11-15 | 2000-01-04 | Institut Pasteur | Altered major histocompatibility complex (MHC) determinant and methods of using the determinant |
US5599924A (en) * | 1992-08-14 | 1997-02-04 | Trustees Of The University Of Pennsylvania | Electron-deficient porphyrins and processes and intermediates for preparing same |
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US5405369A (en) * | 1994-01-25 | 1995-04-11 | Medical College Of Ohio | Photochemical ablation of gastro-intestinal tissue for augmentation of an organ |
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US5948771A (en) * | 1996-01-31 | 1999-09-07 | The Trustees Of Columbia University In The City Of New York | Method for treating heart failure using tetrapyrroles and metallotetrapyrroles |
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EP0988037A1 (en) | 1997-02-05 | 2000-03-29 | Board Of Regents, The University Of Texas System | Porphyrin compounds as telomerase inhibitors |
US6214817B1 (en) * | 1997-06-20 | 2001-04-10 | Monsanto Company | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity |
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DE69813898T2 (de) * | 1997-11-03 | 2004-03-11 | Duke University | Substituierte porphyrinen |
JP3101875B2 (ja) | 1998-12-04 | 2000-10-23 | 末綱 陽子 | 新規なトリペプチドおよび活性化酸素阻害剤 |
ATE312103T1 (de) * | 1999-01-25 | 2005-12-15 | Nat Jewish Med & Res Center | Substituierte porphyrine und deren therapeutische verwendungen |
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WO2001026655A1 (en) * | 1999-10-13 | 2001-04-19 | Uab Research Foundation | Metalloporphyrin treatment of neurologic disease |
US6548045B2 (en) * | 1999-11-30 | 2003-04-15 | Photochemical Co., Ltd. | Nitroimidazole substituted porphyrin complex |
JP3383839B2 (ja) * | 2000-03-13 | 2003-03-10 | 奈良先端科学技術大学院大学長 | 新規なメルカプト置換イミダゾリルポルフィリン金属錯体単量体及びこれを繰り返し単位として有する重合体並びにこれらの製造方法 |
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US6403788B1 (en) * | 2000-07-11 | 2002-06-11 | Eukarion, Inc. | Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species |
US6566517B2 (en) * | 2001-06-06 | 2003-05-20 | Brookhaven Science Associates, Llc | Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy |
-
2002
- 2002-01-22 ES ES02717355T patent/ES2330728T3/es not_active Expired - Lifetime
- 2002-01-22 EP EP02717355A patent/EP1392328B1/en not_active Expired - Lifetime
- 2002-01-22 DE DE60233317T patent/DE60233317D1/de not_active Expired - Lifetime
- 2002-01-22 CA CA2436245A patent/CA2436245C/en not_active Expired - Fee Related
- 2002-01-22 AT AT02717355T patent/ATE439134T1/de not_active IP Right Cessation
- 2002-01-22 WO PCT/US2002/001507 patent/WO2002060383A2/en active Application Filing
- 2002-01-22 US US10/051,367 patent/US20030050297A1/en not_active Abandoned
- 2002-01-22 JP JP2002560579A patent/JP2004520380A/ja not_active Withdrawn
- 2002-01-22 DK DK02717355T patent/DK1392328T3/da active
- 2002-01-22 AU AU2002248366A patent/AU2002248366B2/en not_active Ceased
-
2006
- 2006-11-09 US US11/558,408 patent/US8765729B2/en not_active Expired - Fee Related
-
2009
- 2009-07-08 JP JP2009162200A patent/JP2009242421A/ja active Pending
-
2012
- 2012-01-27 JP JP2012015864A patent/JP2012087148A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2009242421A (ja) | 2009-10-22 |
ATE439134T1 (de) | 2009-08-15 |
EP1392328A4 (en) | 2004-11-17 |
EP1392328B1 (en) | 2009-08-12 |
CA2436245A1 (en) | 2002-08-08 |
DE60233317D1 (de) | 2009-09-24 |
JP2012087148A (ja) | 2012-05-10 |
AU2002248366B2 (en) | 2006-10-26 |
US20070149498A1 (en) | 2007-06-28 |
US8765729B2 (en) | 2014-07-01 |
WO2002060383A2 (en) | 2002-08-08 |
EP1392328A2 (en) | 2004-03-03 |
CA2436245C (en) | 2013-04-23 |
US20030050297A1 (en) | 2003-03-13 |
ES2330728T3 (es) | 2009-12-15 |
JP2004520380A (ja) | 2004-07-08 |
WO2002060383A3 (en) | 2003-12-11 |
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