DK131639B - Process for the preparation of 7beta- (D-5-amino-5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or pharmaceutically acceptable salts thereof. - Google Patents

Process for the preparation of 7beta- (D-5-amino-5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or pharmaceutically acceptable salts thereof.

Info

Publication number: DK131639B
Authority: DK; Denmark
Prior art keywords: carboxyvaleramido; 7beta; carbamoyloxymethyl; cephem; methoxy
Prior art date: 1970-03-13

Application number

DK118171AA

Other languages

Danish (da)

Other versions

DK131639C (en

Inventor

Edward O Stapley

Justo M Mata

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-03-13

Filing date

1971-03-12

Publication date

1975-08-11

1971-02-16 Priority claimed from US05/115,779 external-priority patent/US4302578A/en

1971-03-12 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1973-09-21 Priority to DK517973A priority Critical patent/DK134324B/en

1975-08-11 Publication of DK131639B publication Critical patent/DK131639B/en

1976-01-12 Application granted granted Critical

1976-01-12 Publication of DK131639C publication Critical patent/DK131639C/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK118171A 1970-03-13 1971-03-12 PROCEDURE FOR THE PREPARATION OF 7BETA- (D-5-AMINO-5-CARBOXYVALERAMIDO) -3- (CARBAMOYLOXYMETHYL) -7-METHOXY-3-CEPHEM-4-CARBOXYLIC ACID OR SALPER ACALPH DK131639C (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK517973A DK134324B (en)	1970-03-13	1973-09-21	Process for the preparation of 7beta- (D-5-amino-5-carboxyvaleramido) -3- (alpha-methoxy-p-sulfooxycinnamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or 7beta- (D-5-amino -5-carboxyvaleramido) -3- (alpha-methoxy-p-hydroxycinnamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or a mixture thereof.

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US1949670A	1970-03-13	1970-03-13
US5131970A	1970-06-30	1970-06-30
US9659470A	1970-12-09	1970-12-09
US05/115,779 US4302578A (en)	1970-12-09	1971-02-16	Cephalosporin antibiotics

Publications (2)

Publication Number	Publication Date
DK131639B true DK131639B (en)	1975-08-11
DK131639C DK131639C (en)	1976-01-12

Family

ID=27486855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK118171A DK131639C (en)	1970-03-13	1971-03-12	PROCEDURE FOR THE PREPARATION OF 7BETA- (D-5-AMINO-5-CARBOXYVALERAMIDO) -3- (CARBAMOYLOXYMETHYL) -7-METHOXY-3-CEPHEM-4-CARBOXYLIC ACID OR SALPER ACALPH

Country Status (19)

Country	Link
JP (1)	JPS581919B1 (en)
AR (3)	AR200370A1 (en)
BE (1)	BE764160A (en)
CA (1)	CA960169A (en)
CH (5)	CH579576A5 (en)
DD (3)	DD100002A5 (en)
DE (3)	DE2109854C3 (en)
DK (1)	DK131639C (en)
FI (1)	FI51484C (en)
FR (1)	FR2085702B1 (en)
GB (1)	GB1321412A (en)
IE (1)	IE35110B1 (en)
IL (1)	IL36281A (en)
IT (1)	IT1045524B (en)
NL (1)	NL171285C (en)
NO (1)	NO134219C (en)
PH (1)	PH12292A (en)
SE (1)	SE385713B (en)
YU (1)	YU35164B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1040620A (en) *	1972-11-14	1978-10-17	Frank J. Urban	6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process
US4065356A (en)	1976-02-12	1977-12-27	Merck & Co., Inc.	Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans
US4327093A (en)	1978-10-24	1982-04-27	Fujisawa Pharmaceutical Co., Ltd.	3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
JPS5931517B2 (en) *	1978-12-12	1984-08-02	山之内製薬株式会社	New 7↓-methoxycephalosporin derivative
US4379920A (en) *	1979-10-31	1983-04-12	Glaxo Group Limited	Cephalosporins
EP0137365A3 (en) *	1983-09-06	1986-01-15	Takeda Chemical Industries, Ltd.	Cephalosporins and their production
EP0160745A3 (en) *	1984-05-07	1986-11-05	Takeda Chemical Industries, Ltd.	Cephem compounds and their production
CN1795197B (en)	2003-05-28	2010-06-02	帝斯曼知识产权资产管理有限公司	Cephem compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS4945594A (en) *	1972-09-08	1974-05-01

1971
- 1971-02-24 IL IL36281A patent/IL36281A/en unknown
- 1971-03-02 DE DE2109854A patent/DE2109854C3/en not_active Expired
- 1971-03-02 DE DE19712166463 patent/DE2166463A1/en active Pending
- 1971-03-02 DE DE19712166462 patent/DE2166462B2/en active Granted
- 1971-03-08 CH CH333371A patent/CH579576A5/xx not_active IP Right Cessation
- 1971-03-08 CH CH1273075A patent/CH587911A5/xx not_active IP Right Cessation
- 1971-03-08 CH CH1273175A patent/CH586226A5/xx not_active IP Right Cessation
- 1971-03-08 CH CH1294175A patent/CH587856A5/de not_active IP Right Cessation
- 1971-03-08 AR AR234333A patent/AR200370A1/en active
- 1971-03-08 PH PH12269A patent/PH12292A/en unknown
- 1971-03-08 CH CH1294275A patent/CH589655A5/xx not_active IP Right Cessation
- 1971-03-10 IE IE303/71A patent/IE35110B1/en unknown
- 1971-03-11 FI FI710711A patent/FI51484C/en active
- 1971-03-11 SE SE7103119A patent/SE385713B/en unknown
- 1971-03-12 CA CA107,642A patent/CA960169A/en not_active Expired
- 1971-03-12 YU YU626/71A patent/YU35164B/en unknown
- 1971-03-12 DD DD164638A patent/DD100002A5/xx unknown
- 1971-03-12 DD DD153734A patent/DD96254A5/xx unknown
- 1971-03-12 DD DD164639A patent/DD99166A5/xx unknown
- 1971-03-12 DK DK118171A patent/DK131639C/en not_active IP Right Cessation
- 1971-03-12 FR FR7108668A patent/FR2085702B1/fr not_active Expired
- 1971-03-12 BE BE764160A patent/BE764160A/en not_active IP Right Cessation
- 1971-03-12 IT IT49017/71A patent/IT1045524B/en active
- 1971-03-12 NL NLAANVRAGE7103360,A patent/NL171285C/en not_active IP Right Cessation
- 1971-03-12 NO NO932/71A patent/NO134219C/no unknown
- 1971-03-13 JP JP46013630A patent/JPS581919B1/ja active Pending
- 1971-04-19 GB GB2340771*A patent/GB1321412A/en not_active Expired
1972
- 1972-05-31 AR AR242279A patent/AR212149A1/en active
1974
- 1974-04-29 AR AR253505A patent/AR201142A1/en active

Also Published As

Publication number	Publication date
AR212149A1 (en)	1978-05-31
BE764160A (en)	1971-09-13
FI51484C (en)	1977-01-10
CA960169A (en)	1974-12-31
CH587911A5 (en)	1977-05-13
DE2109854C3 (en)	1975-06-05
AR200370A1 (en)	1974-11-08
DE2166462A1 (en)	1974-05-09
JPS581919B1 (en)	1983-01-13
CH579576A5 (en)	1976-09-15
SE385713B (en)	1976-07-19
DD99166A5 (en)	1973-07-20
DE2109854A1 (en)	1971-09-23
IL36281A0 (en)	1971-04-28
CH589655A5 (en)	1977-07-15
NO134219C (en)	1976-09-01
DK131639C (en)	1976-01-12
IT1045524B (en)	1980-05-10
FI51484B (en)	1976-09-30
CH587856A5 (en)	1977-05-13
CH586226A5 (en)	1977-03-31
NL171285C (en)	1983-03-01
PH12292A (en)	1978-12-29
GB1321412A (en)	1973-06-27
AR201142A1 (en)	1975-02-14
YU62671A (en)	1979-12-31
IE35110B1 (en)	1975-11-12
DE2166462B2 (en)	1977-01-20
YU35164B (en)	1980-09-25
FR2085702A1 (en)	1971-12-31
NL7103360A (en)	1971-09-15
DE2166463A1 (en)	1974-05-02
DD96254A5 (en)	1973-03-12
IL36281A (en)	1977-04-29
NL171285B (en)	1982-10-01
FR2085702B1 (en)	1974-08-23
DE2109854B2 (en)	1974-09-26
IE35110L (en)	1971-09-13
NO134219B (en)	1976-05-24
DD100002A5 (en)	1973-09-05

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Legal Events

Date	Code	Title	Description
1988-03-07	PBP	Patent lapsed