DK128380A - 4-amino-3-quinolin-carboxylsyrer og syreestere deres fremstilling og anvendelse - Google Patents

4-amino-3-quinolin-carboxylsyrer og syreestere deres fremstilling og anvendelse

Info

Publication number
DK128380A
DK128380A DK128380A DK128380A DK128380A DK 128380 A DK128380 A DK 128380A DK 128380 A DK128380 A DK 128380A DK 128380 A DK128380 A DK 128380A DK 128380 A DK128380 A DK 128380A
Authority
DK
Denmark
Prior art keywords
amino
preparation
acid esters
carboxylic acids
quinoline carboxylic
Prior art date
Application number
DK128380A
Other languages
English (en)
Other versions
DK156056C (da
DK156056B (da
Inventor
H R Munson
R S Alphin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of DK128380A publication Critical patent/DK128380A/da
Publication of DK156056B publication Critical patent/DK156056B/da
Application granted granted Critical
Publication of DK156056C publication Critical patent/DK156056C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK128380A 1979-03-26 1980-03-25 Analogifremgangsmaade til fremstilling af 4-amino-3-quinolin-carboxylsyrederivater DK156056C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US2398179 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
US12715380 1980-03-04

Publications (3)

Publication Number Publication Date
DK128380A true DK128380A (da) 1980-09-27
DK156056B DK156056B (da) 1989-06-19
DK156056C DK156056C (da) 1989-11-06

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
DK128380A DK156056C (da) 1979-03-26 1980-03-25 Analogifremgangsmaade til fremstilling af 4-amino-3-quinolin-carboxylsyrederivater

Country Status (31)

Country Link
US (1) US4343804A (da)
JP (1) JPH02117663A (da)
AR (1) AR230268A1 (da)
AT (1) AT372373B (da)
AU (1) AU528388B2 (da)
BR (1) BR8001779A (da)
CA (1) CA1147338A (da)
CH (1) CH644105A5 (da)
DE (1) DE3011490A1 (da)
DK (1) DK156056C (da)
EG (1) EG15009A (da)
ES (1) ES8103048A1 (da)
FI (1) FI77452C (da)
FR (1) FR2452485B1 (da)
GB (1) GB2047244B (da)
GR (1) GR68006B (da)
HK (1) HK67983A (da)
IE (1) IE49577B1 (da)
IL (1) IL59628A (da)
IN (1) IN151446B (da)
IT (1) IT1133079B (da)
MX (1) MX6264E (da)
NL (1) NL8001752A (da)
NO (1) NO153927C (da)
NZ (1) NZ193252A (da)
PH (1) PH16416A (da)
PL (1) PL125030B1 (da)
PT (1) PT71008B (da)
SE (1) SE435837B (da)
SG (1) SG33683G (da)
YU (1) YU41702B (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
NZ269827A (en) * 1993-08-10 1996-10-28 Black James Foundation (hetero)aryl gastin and cck receptor ligands having a carboxy group(or derivative) or two carboxy groups(or derivatives)on adjacent carbon atoms
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
NZ510580A (en) 1998-09-29 2003-03-28 American Cyanamid Co Substituted 3-cyanoquinolines useful as protein tyrosine kinases inhibitors
ES2246922T3 (es) * 1999-12-28 2006-03-01 Eisai Co., Ltd. Compuestos heterociclicos que tienen grupos de sulfonamida.
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EP1599468B1 (en) 2003-01-14 2007-10-03 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
AU2004220357B2 (en) 2003-03-10 2010-09-30 Astrazeneca Ab Novel process for the preparation of roflumilast
CN102417508A (zh) * 2003-07-14 2012-04-18 艾尼纳制药公司 作为新陈代谢调节剂的稠合芳基和杂芳基衍生物以及预防和治疗与其相关的病症
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
SG182610A1 (en) 2010-01-27 2012-08-30 Arena Pharm Inc Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
KR101871011B1 (ko) 2010-09-22 2018-06-25 아레나 파마슈티칼스, 인크. Ｇｐｒ１１９ 수용체의 조절제 및 그와 관련된 장애의 치료
MX2017008925A (es) 2015-01-06 2017-10-11 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
PT3310760T (pt) 2015-06-22 2022-11-10 Arena Pharm Inc Sal cristalino de l-arginina de ácido (r)-2-(7-(4-ciclopentil-3-(trifluorometil)benziloxi)-1,2,3,4-tetrahidrociclo-penta[b]indol-3-il)acético para utilização em distúrbios associados a recetores de s1p1
KR102595730B1 (ko) * 2016-11-11 2023-10-27 바이엘 애니멀 헬스 게엠베하 새로운 구충 퀴놀린-3-카르복스아미드 유도체
JP2020507611A (ja) 2017-02-16 2020-03-12 アリーナ ファーマシューティカルズ， インコーポレイテッド 原発性胆汁性胆管炎の治療のための化合物および方法
WO2019084271A1 (en) * 2017-10-25 2019-05-02 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHODS OF USE
MX2020011873A (es) 2018-05-09 2021-01-20 Bayer Animal Health Gmbh Nuevos derivados de quinolina.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (da) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
IT1133079B (it) 1986-07-09
IE49577B1 (en) 1985-10-30
US4343804A (en) 1982-08-10
IL59628A0 (en) 1980-06-30
YU41702B (en) 1987-12-31
PT71008B (en) 1981-06-25
CH644105A5 (fr) 1984-07-13
NO153927C (no) 1986-06-18
DK156056C (da) 1989-11-06
SE8002292L (sv) 1980-09-27
IN151446B (da) 1983-04-23
SG33683G (en) 1985-03-29
NZ193252A (en) 1984-04-27
YU84480A (en) 1983-10-31
FR2452485A1 (fr) 1980-10-24
BR8001779A (pt) 1980-11-18
IE800605L (en) 1980-09-26
PL125030B1 (en) 1983-03-31
GB2047244A (en) 1980-11-26
DE3011490C2 (da) 1988-12-22
DE3011490A1 (de) 1981-03-12
EG15009A (en) 1985-03-31
ATA156480A (de) 1983-02-15
ES489887A0 (es) 1981-02-16
FR2452485B1 (fr) 1986-09-12
HK67983A (en) 1983-12-23
GB2047244B (en) 1983-02-23
FI77452C (fi) 1989-03-10
FI800910A (fi) 1980-09-27
IT8067465A0 (it) 1980-03-26
NO800858L (no) 1980-09-29
ES8103048A1 (es) 1981-02-16
AU5684880A (en) 1980-10-02
IL59628A (en) 1983-06-15
AT372373B (de) 1983-09-26
PT71008A (en) 1980-04-01
GR68006B (da) 1981-10-26
CA1147338A (en) 1983-05-31
SE435837B (sv) 1984-10-22
JPH02117663A (ja) 1990-05-02
PH16416A (en) 1983-09-29
PL222993A1 (da) 1981-01-30
FI77452B (fi) 1988-11-30
AR230268A1 (es) 1984-03-01
NO153927B (no) 1986-03-10
AU528388B2 (en) 1983-04-28
MX6264E (es) 1985-02-19
NL8001752A (nl) 1980-09-30
DK156056B (da) 1989-06-19

Similar Documents

Publication Publication Date Title
DK128380A (da) 4-amino-3-quinolin-carboxylsyrer og syreestere deres fremstilling og anvendelse
TR19917A (tr) Siklopropan karboksilik asitlerin substituee edilmis pridin metil esterleri ve bunlarin ensektisidler olarak kullanimi
DK79077A (da) Estere af androstadien-17-carboxylsyrer og fremgangsmade til fremstilling deraf
JPS5695134A (en) Simultaneous manufacture of carboxylic acid and carboxylic acid ester
JPS5538369A (en) Manufacture of carboxylic acids and their esters
NO801046L (no) Penem-3-karboksylsyrederivater og fremgangsmaate til fremstilling av samme
DK294180A (da) Hidtil ukendte carboxylsyrederivater deres fremstilling og anvendelse
NO883728D0 (no) Fremgangsmaate for asymmetrisk fremstilling av karboksylsyreestere og/eller karboksylsyrer.
DK197878A (da) Substituerede 2-aryloxy-2-(p-phenoxyalkoxy)-phenyleddikesyrer og estere samt deres fremstilling og anvendelse
DK102278A (da) Fremgangsmaade til fremstilling af dihalogenvinyl-cyclopropancarboxylsyrer og deres estere
NZ188650A (en) Preparation of esters of meta-phenoxybenzyl alcohol and derivatives with carboxylic acids
GB8300411D0 (en) Intermediates in preparation of carboxylic acid derivatives
DK296379A (da) 2-cyclopropyl-pyrimidin-(4)-yl-thionophosphonsyreestere deres fremstilling og anvendelse
NO883897D0 (no) 4-okso-quinolinkarboksylsyrer og deres fremstilling derav.
DE3064472D1 (en) Preparation of acids and esters
DK59279A (da) Modficerede azulminsyrer deres fremstilling og anvendelse
IT1100998B (it) Procedimento per produrre acidi carbossilici alifatici e esteri di acidi carbossilici alifatici di fenol
JPS5283373A (en) 44methylimidazolee55 carboxylic acid isopropyl ester and preparation thereof
EG12151A (en) Novel phenoxybenzyl esters of spirocarboxylic acids and their use as insecticides
NO802217L (no) Fremgangsmaate til fremstilling av fluorerte metylaminoalkansyrer og mellomprodukter for bruk i fremgangsmaaten
BR8008821A (pt) Interpolimeros hidrofilos fotopolimerizados de acidos e esteres carboxilicos insaturados
MX153577A (es) Procedimiento para preparar esteres de acidos carboxilicos
DK242378A (da) Derivater af thiazolidincarboxylsyrer og dermed beslaegtede syrer
DK78779A (da) Substituerede imidazolidinyl-3-klor-3-cephem-4-carboxylsyrer og fremgangsmaade til fremstilling deraf
AR227638A1 (es) Procedimiento de preparacion de esteres de acidos clorobencil-fenoxi-carboxilicos

Legal Events

Date Code Title Description
PBP Patent lapsed