DK1223930T3 - Behandling af dyskinesi - Google Patents
Behandling af dyskinesiInfo
- Publication number
- DK1223930T3 DK1223930T3 DK00972966T DK00972966T DK1223930T3 DK 1223930 T3 DK1223930 T3 DK 1223930T3 DK 00972966 T DK00972966 T DK 00972966T DK 00972966 T DK00972966 T DK 00972966T DK 1223930 T3 DK1223930 T3 DK 1223930T3
- Authority
- DK
- Denmark
- Prior art keywords
- dyskinesia
- treatment
- compounds
- histamine receptor
- activation
- Prior art date
Links
- 208000012661 Dyskinesia Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229960001340 histamine Drugs 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Resistance Heating (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9924941.9A GB9924941D0 (en) | 1999-10-22 | 1999-10-22 | Treatment of dyskinesia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1223930T3 true DK1223930T3 (da) | 2006-11-20 |
Family
ID=10863143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00972966T DK1223930T3 (da) | 1999-10-22 | 2000-10-20 | Behandling af dyskinesi |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7935718B2 (de) |
| EP (1) | EP1223930B1 (de) |
| JP (1) | JP5175015B2 (de) |
| AT (1) | ATE333277T1 (de) |
| AU (1) | AU782357B2 (de) |
| CA (1) | CA2389476C (de) |
| CY (1) | CY1106194T1 (de) |
| DE (1) | DE60029463T2 (de) |
| DK (1) | DK1223930T3 (de) |
| ES (1) | ES2267581T3 (de) |
| GB (1) | GB9924941D0 (de) |
| PT (1) | PT1223930E (de) |
| WO (1) | WO2001030346A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5392770A (en) * | 1993-06-29 | 1995-02-28 | Clawson; Burrell E. | Tubing circuit systems for humidified respiratory gas |
| GB0007193D0 (en) * | 2000-03-25 | 2000-05-17 | Univ Manchester | Treatment of movrmrnt disorders |
| GB0027020D0 (en) * | 2000-11-03 | 2000-12-20 | Univ Manchester | Treatment of movement disorders |
| WO2005097111A2 (en) * | 2004-03-26 | 2005-10-20 | Merck & Co., Inc. | Treatment of tremor with histamine h3 inverse agonists or histamine h3 antagonists |
| EP1707203A1 (de) * | 2005-04-01 | 2006-10-04 | Bioprojet | Verwendung von Alkylaminen, die kein Imidazole enthalten, als Histamin H3 Rezeptor Liganden, zur Behandlung von Morbus Parkinson, obstruktiver Schlafapnoe, vaskularer Demenz, Demenz mit Lewy Korpen |
| DE102005029468A1 (de) * | 2005-06-24 | 2006-12-28 | Plt Patent & Licence Trading Ltd. | Verwendung von Inhibitoren der N-Methyltransferasen in der Therapie des Parkinson-Syndroms |
| MX2009011449A (es) * | 2007-04-24 | 2010-01-25 | Toray Industries | Agente terapeutico o profilactico para disquinesia. |
| US11426366B2 (en) | 2015-05-15 | 2022-08-30 | Arizona Board Of Regents On Behalf Of The Universsity Of Arizona | Compositions and methods for treating motor disorders |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586562B1 (fr) * | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| US4816456A (en) * | 1986-10-01 | 1989-03-28 | Summers William K | Administration of monoamine acridines in cholinergic neuronal deficit states |
| US5091428A (en) * | 1987-04-24 | 1992-02-25 | Syntex Pharmaceuticals, Ltd. | Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives |
| US5821259A (en) * | 1991-11-12 | 1998-10-13 | Theoharides; Theoharis C. | H3 -receptor agonists as therapeutic agents |
| WO1993012108A1 (en) * | 1991-12-18 | 1993-06-24 | Schering Corporation | Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring |
| AU4078997A (en) * | 1996-08-22 | 1998-03-06 | New York University | Cholinesterase inhibitors for treatment of parkinson's disease |
| US6028169A (en) | 1997-03-31 | 2000-02-22 | Human Genome Sciences, Inc. | Chemokine β-6 antagonists |
| GB9815618D0 (en) * | 1998-07-18 | 1998-09-16 | Univ Manchester | Treatment of dyskinesia |
| AU757749B2 (en) * | 1998-10-07 | 2003-03-06 | Ortho-Mcneil Pharmaceutical, Inc. | Isolated DNA encoding human H3 histamine receptor |
| US6136559A (en) * | 1998-10-07 | 2000-10-24 | Ortho Pharmaceutical Corporation | DNA encoding as human histamine receptor of the H3 subtype |
| GB0027020D0 (en) * | 2000-11-03 | 2000-12-20 | Univ Manchester | Treatment of movement disorders |
| US6316475B1 (en) * | 2000-11-17 | 2001-11-13 | Abbott Laboratories | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications |
| US7754210B2 (en) * | 2002-06-25 | 2010-07-13 | Xu Kai Y | Inotropic antibodies and therapeutic uses thereof |
| ES2285245T3 (es) * | 2002-09-13 | 2007-11-16 | Motac Neuroscience Limited | Tratamiento de la disquinesia con 2,3-benzodiazapinas. |
| AU2003267557B2 (en) * | 2002-09-17 | 2009-02-26 | Motac Neuroscience Limited | Treatment of dyskinesia |
-
1999
- 1999-10-22 GB GBGB9924941.9A patent/GB9924941D0/en not_active Ceased
-
2000
- 2000-10-20 DK DK00972966T patent/DK1223930T3/da active
- 2000-10-20 AU AU11523/01A patent/AU782357B2/en not_active Ceased
- 2000-10-20 ES ES00972966T patent/ES2267581T3/es not_active Expired - Lifetime
- 2000-10-20 CA CA002389476A patent/CA2389476C/en not_active Expired - Fee Related
- 2000-10-20 WO PCT/GB2000/004046 patent/WO2001030346A1/en active IP Right Grant
- 2000-10-20 JP JP2001532766A patent/JP5175015B2/ja not_active Expired - Fee Related
- 2000-10-20 DE DE60029463T patent/DE60029463T2/de not_active Expired - Lifetime
- 2000-10-20 EP EP00972966A patent/EP1223930B1/de not_active Expired - Lifetime
- 2000-10-20 PT PT00972966T patent/PT1223930E/pt unknown
- 2000-10-20 AT AT00972966T patent/ATE333277T1/de active
-
2004
- 2004-10-28 US US10/974,980 patent/US7935718B2/en not_active Expired - Fee Related
-
2006
- 2006-10-12 CY CY20061101463T patent/CY1106194T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE333277T1 (de) | 2006-08-15 |
| AU782357B2 (en) | 2005-07-21 |
| JP5175015B2 (ja) | 2013-04-03 |
| AU1152301A (en) | 2001-05-08 |
| JP2003512428A (ja) | 2003-04-02 |
| PT1223930E (pt) | 2006-12-29 |
| US20050245587A1 (en) | 2005-11-03 |
| GB9924941D0 (en) | 1999-12-22 |
| EP1223930B1 (de) | 2006-07-19 |
| ES2267581T3 (es) | 2007-03-16 |
| DE60029463T2 (de) | 2007-02-15 |
| CA2389476C (en) | 2010-03-09 |
| EP1223930A1 (de) | 2002-07-24 |
| WO2001030346A1 (en) | 2001-05-03 |
| DE60029463D1 (de) | 2006-08-31 |
| CY1106194T1 (el) | 2011-06-08 |
| CA2389476A1 (en) | 2001-05-03 |
| US7935718B2 (en) | 2011-05-03 |
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