DK1210123T3 - Enkeltstrengede oligodeoxynucleotidvektorer egnede til mutation - Google Patents
Enkeltstrengede oligodeoxynucleotidvektorer egnede til mutationInfo
- Publication number
- DK1210123T3 DK1210123T3 DK00959442.5T DK00959442T DK1210123T3 DK 1210123 T3 DK1210123 T3 DK 1210123T3 DK 00959442 T DK00959442 T DK 00959442T DK 1210123 T3 DK1210123 T3 DK 1210123T3
- Authority
- DK
- Denmark
- Prior art keywords
- effective
- oligodeoxynucleotides
- mutation
- vectors suitable
- stranded oligodeoxynucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/384,960 US6271360B1 (en) | 1999-08-27 | 1999-08-27 | Single-stranded oligodeoxynucleotide mutational vectors |
PCT/US2000/023457 WO2001015740A1 (en) | 1999-08-27 | 2000-08-25 | Single-stranded oligodeoxynucleotide mutational vectors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1210123T3 true DK1210123T3 (da) | 2010-12-20 |
Family
ID=23519459
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10008602.4T DK2266627T3 (da) | 1999-08-27 | 2000-08-25 | Enkeltstrengede oligodeoxynukleotide mutationsvektorer |
DK10183960.3T DK2324856T3 (da) | 1999-08-27 | 2000-08-25 | Enkeltstrengede oligodeoxynukleotide mutationsvektorer |
DK00959442.5T DK1210123T3 (da) | 1999-08-27 | 2000-08-25 | Enkeltstrengede oligodeoxynucleotidvektorer egnede til mutation |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10008602.4T DK2266627T3 (da) | 1999-08-27 | 2000-08-25 | Enkeltstrengede oligodeoxynukleotide mutationsvektorer |
DK10183960.3T DK2324856T3 (da) | 1999-08-27 | 2000-08-25 | Enkeltstrengede oligodeoxynukleotide mutationsvektorer |
Country Status (15)
Country | Link |
---|---|
US (3) | US6271360B1 (da) |
EP (3) | EP2324856B1 (da) |
JP (2) | JP5697187B2 (da) |
CN (1) | CN1384759B (da) |
AT (1) | ATE478687T1 (da) |
AU (2) | AU773242C (da) |
BR (1) | BR0013590A (da) |
CA (1) | CA2382120C (da) |
DE (1) | DE60044876D1 (da) |
DK (3) | DK2266627T3 (da) |
ES (3) | ES2544727T3 (da) |
NZ (1) | NZ517942A (da) |
PT (3) | PT2324856E (da) |
WO (1) | WO2001015740A1 (da) |
ZA (1) | ZA200201228B (da) |
Families Citing this family (42)
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US6652607B2 (en) | 1999-07-07 | 2003-11-25 | The Lubrizol Corporation | Concentrated emulsion for making an aqueous hydrocarbon fuel |
EP1212406A1 (en) * | 1999-08-20 | 2002-06-12 | University Of Delaware | Cell-free assay for plant gene targeting and conversion |
US6271360B1 (en) * | 1999-08-27 | 2001-08-07 | Valigen (Us), Inc. | Single-stranded oligodeoxynucleotide mutational vectors |
AR025996A1 (es) | 1999-10-07 | 2002-12-26 | Valigen Us Inc | Plantas no transgenicas resistentes a los herbicidas. |
WO2001073002A2 (en) * | 2000-03-27 | 2001-10-04 | University Of Delaware | Targeted chromosomal genomic alterations with modified single stranded oligonucleotides |
US6936467B2 (en) * | 2000-03-27 | 2005-08-30 | University Of Delaware | Targeted chromosomal genomic alterations with modified single stranded oligonucleotides |
WO2001087914A2 (en) * | 2000-05-17 | 2001-11-22 | University Of Delaware | Plant gene targeting using oligonucleotides |
AU2001279069A1 (en) * | 2000-07-27 | 2002-02-13 | University Of Delaware | Methods for enhancing targeted gene alteration using oligonucleotides |
US7053195B1 (en) * | 2001-06-12 | 2006-05-30 | Syngenta Participatious Ag | Locked nucleic acid containing heteropolymers and related methods |
US20040096880A1 (en) * | 2001-08-07 | 2004-05-20 | Kmiec Eric B. | Compositions and methods for the treatment of diseases exhibiting protein misassembly and aggregation |
US20030109476A1 (en) * | 2001-08-07 | 2003-06-12 | Kmiec Eric B. | Compositions and methods for the prevention and treatment of Huntington's disease |
EP1446503A2 (en) * | 2001-09-27 | 2004-08-18 | University Of Delaware | Composition and methods for enhancing oligonucleotide-directed nucleic acid sequence alteration |
US20030207327A1 (en) * | 2001-09-27 | 2003-11-06 | Kmiec Eric B. | Coisogenic eukaryotic cell collections |
JP2005518817A (ja) * | 2002-03-07 | 2005-06-30 | ユニバーシティー、オブ、デラウェア | ヒストン・デアセチラーゼ・インヒビタ、ラムダファージベータ蛋白、またはヒドロキシウレアを含む組成物を使用してオリゴヌクレオチド媒介性核酸配列改変を高める方法、組成物およびキット |
GB0218803D0 (en) * | 2002-08-13 | 2002-09-18 | Nl Kanker I | Targeted gene modification by single-standed DNA oligonucleotides |
AU2003282477A1 (en) * | 2002-10-07 | 2004-05-04 | Napro Bio Therapeutics, Inc. | Methods and compositions for reducing screening in oligonucleotide-directed nucleic acid sequence alteration |
US6929917B2 (en) * | 2002-11-18 | 2005-08-16 | Pregentis | Method for cloning of a rare, specifically mutated cell |
US20070072815A1 (en) * | 2004-05-04 | 2007-03-29 | Kmiec Eric B | Methods and kits to increase the efficiency of oligonucleotide-directed nucleic acid sequence alteration |
PL2465341T3 (pl) | 2006-01-12 | 2015-06-30 | Cibus Europe Bv | Mutanty EPSPS |
NZ574390A (en) * | 2006-06-28 | 2012-04-27 | Coh Inc | Fatty acid blends and uses therefor in fuel |
EP2177605B1 (de) | 2006-10-06 | 2014-12-10 | BASF Plant Science GmbH | Delta-5 Desaturasen und Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen nicht-humanen Organismen |
US9102948B2 (en) | 2006-11-17 | 2015-08-11 | 22Nd Century Limited, Llc | Regulating alkaloids |
BR122018070230B1 (pt) * | 2007-10-05 | 2023-01-10 | Cibus Europe B.V. | Método para produção de planta resistente à herbicida |
ES2653573T3 (es) * | 2007-12-27 | 2018-02-07 | Cibus Europe B.V. | Mezclas de éster butílico de ácido graso |
AU2009248852B9 (en) | 2008-05-23 | 2015-08-13 | Cibus Europe B.V. | Production of squalene using yeast |
WO2010036771A2 (en) | 2008-09-26 | 2010-04-01 | Basf Agrochemical Products B.V. | Herbicide-resistant ahas-mutants and methods of use |
AU2009326129B2 (en) | 2008-12-12 | 2016-05-12 | Basf Plant Science Gmbh | Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms |
HUE034245T2 (en) * | 2009-11-23 | 2018-02-28 | Nucelis Llc | Methods and preparations for the preparation of squalene using yeast |
UA112969C2 (uk) | 2010-08-03 | 2016-11-25 | Сібас Юс Ллс | Рослина, стійка до одного або більше ррх-інгібуючих гербіцидів, яка містить мутантний ген протопорфіриноген ix оксидази (ррх) |
US20120122223A1 (en) | 2010-08-03 | 2012-05-17 | Cibus Us Llc | Mutated protoporphyrinogen ix oxidase (ppx) genes |
WO2012028673A1 (en) | 2010-09-02 | 2012-03-08 | Ludwig-Maximilians-Universitaet Muenchen | Spontaneous organogenesis in plants |
EP2426204A1 (en) | 2010-09-02 | 2012-03-07 | Ludwig-Maximilians-Universität München | Spontaneous nodule organogenesis in plants |
KR101137285B1 (ko) | 2010-10-28 | 2012-04-20 | 위월드 주식회사 | 초소형 광대역 송수신 안테나 피더 |
KR20150041788A (ko) | 2012-08-17 | 2015-04-17 | 다우 아그로사이언시즈 엘엘씨 | 식물에서의 트랜스진 발현을 위한 옥수수 비번역 영역의 용도 |
CN114703210A (zh) | 2013-03-14 | 2022-07-05 | 希博斯美国有限公司 | 突变的丙二烯氧合酶2(aos2)基因 |
ES2921207T3 (es) | 2013-03-15 | 2022-08-19 | Cibus Us Llc | Procedimientos y composiciones para aumentar la eficiencia de la modificación genética direccionada utilizando la reparación genética mediada por oligonucleótidos |
US9957515B2 (en) | 2013-03-15 | 2018-05-01 | Cibus Us Llc | Methods and compositions for targeted gene modification |
SI2966984T1 (sl) | 2013-03-15 | 2022-06-30 | Cibus Us Llc | Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka |
KR20230127356A (ko) | 2014-03-14 | 2023-08-31 | 시버스 유에스 엘엘씨 | 올리고뉴클레오타이드 매개 유전자 보수를 사용한 표적화된유전자 변형의 효율을 증가시키기 위한 방법 및 조성물 |
KR20180116769A (ko) | 2016-02-09 | 2018-10-25 | 시버스 유에스 엘엘씨 | 올리고뉴클레오타이드 매개 유전자 보수를 사용한 표적화된 유전자 변형의 효율을 증가시키기 위한 방법 및 조성물 |
US10584363B2 (en) | 2016-06-03 | 2020-03-10 | Takara Bio Usa, Inc. | Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same |
AU2019207703A1 (en) | 2018-01-09 | 2020-07-16 | Cibus Europe B.V. | Shatterproof genes and mutations |
Family Cites Families (23)
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JP2731844B2 (ja) * | 1987-04-22 | 1998-03-25 | ザ・ユニヴァーシティー・オブ・コネチカット | 哺乳動物の細胞にポリヌクレオチドを導入するキャリア及び水溶性高分子複合体並びにその導入方法 |
ES2099718T3 (es) * | 1990-07-02 | 1997-06-01 | Hoechst Ag | Analogos de oligonucleotidos con uniones internucleotidicas de 3'-3' o 5'-5' terminales. |
AU681997B2 (en) | 1991-09-05 | 1997-09-18 | University Of Connecticut, The | Targeted delivery of poly- or oligonucleotides to cells |
US5808044A (en) * | 1993-01-22 | 1998-09-15 | Pharmacia Biotech Inc. | Indocarbocyanine and benzindocarbocyanine phosphoramidites |
US5556959A (en) | 1993-01-22 | 1996-09-17 | Pharmacia P-L Biochemicals Inc. | Indocarbocyanine-linked phosphoramidites |
WO1995015972A1 (en) | 1993-12-09 | 1995-06-15 | Thomas Jefferson University | Compounds and methods for site-directed mutations in eukaryotic cells |
US5780296A (en) | 1995-01-17 | 1998-07-14 | Thomas Jefferson University | Compositions and methods to promote homologous recombination in eukaryotic cells and organisms |
WO1996040271A1 (en) * | 1995-06-07 | 1996-12-19 | Yale University | Treatment of hemoglobinopathies |
US5908777A (en) * | 1995-06-23 | 1999-06-01 | University Of Pittsburgh | Lipidic vector for nucleic acid delivery |
FR2736926B1 (fr) | 1995-07-19 | 1997-08-22 | Rhone Poulenc Agrochimie | 5-enol pyruvylshikimate-3-phosphate synthase mutee, gene codant pour cette proteine et plantes transformees contenant ce gene |
US5760012A (en) | 1996-05-01 | 1998-06-02 | Thomas Jefferson University | Methods and compounds for curing diseases caused by mutations |
US5888983A (en) | 1996-05-01 | 1999-03-30 | Thomas Jefferson University | Method and oligonucleobase compounds for curing diseases caused by mutations |
US5731181A (en) | 1996-06-17 | 1998-03-24 | Thomas Jefferson University | Chimeric mutational vectors having non-natural nucleotides |
CA2282729A1 (en) * | 1997-02-26 | 1998-09-03 | The General Hospital Corporation | Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of alzheimer's disease |
US6524613B1 (en) | 1997-04-30 | 2003-02-25 | Regents Of The University Of Minnesota | Hepatocellular chimeraplasty |
WO1998049350A1 (en) | 1997-04-30 | 1998-11-05 | Regents Of The University Of Minnesota | In vivo use of recombinagenic oligonucleobases to correct genetic lesions in hepatocytes |
GB9711015D0 (en) | 1997-05-28 | 1997-07-23 | Zeneca Ltd | Improvements in or relating to organic compounds |
US5986086A (en) * | 1997-06-20 | 1999-11-16 | Amersham Pharmacia Biotech Inc. | Non-sulfonated cyanine dyes for labeling nucleosides and nucleotides |
KR20010022652A (ko) | 1997-08-05 | 2001-03-26 | 키메라젠, 인크. | 식물에서 국소적인 유전자변형을 유발하기 위한 혼성 이중나선올리고뉴클레오티드의 용도 |
AU1526199A (en) | 1997-11-18 | 1999-06-07 | Pioneer Hi-Bred International, Inc. | Targeted manipulation of herbicide-resistance genes in plants |
US6004804A (en) | 1998-05-12 | 1999-12-21 | Kimeragen, Inc. | Non-chimeric mutational vectors |
US6271360B1 (en) * | 1999-08-27 | 2001-08-07 | Valigen (Us), Inc. | Single-stranded oligodeoxynucleotide mutational vectors |
WO2016028625A1 (en) | 2014-08-21 | 2016-02-25 | Corning Incorporated | Methods for preventing blisters in laminated glass articles and laminated glass articles formed therefrom |
-
1999
- 1999-08-27 US US09/384,960 patent/US6271360B1/en not_active Expired - Lifetime
-
2000
- 2000-08-25 CN CN008149968A patent/CN1384759B/zh not_active Expired - Lifetime
- 2000-08-25 EP EP20100183960 patent/EP2324856B1/en not_active Expired - Lifetime
- 2000-08-25 EP EP00959442A patent/EP1210123B1/en not_active Expired - Lifetime
- 2000-08-25 PT PT101839603T patent/PT2324856E/pt unknown
- 2000-08-25 DK DK10008602.4T patent/DK2266627T3/da active
- 2000-08-25 DK DK10183960.3T patent/DK2324856T3/da active
- 2000-08-25 PT PT100086024T patent/PT2266627E/pt unknown
- 2000-08-25 DE DE60044876T patent/DE60044876D1/de not_active Expired - Lifetime
- 2000-08-25 ES ES10183960.3T patent/ES2544727T3/es not_active Expired - Lifetime
- 2000-08-25 WO PCT/US2000/023457 patent/WO2001015740A1/en active IP Right Grant
- 2000-08-25 BR BR0013590-9A patent/BR0013590A/pt not_active Application Discontinuation
- 2000-08-25 CA CA2382120A patent/CA2382120C/en not_active Expired - Lifetime
- 2000-08-25 JP JP2001520151A patent/JP5697187B2/ja not_active Expired - Lifetime
- 2000-08-25 EP EP20100008602 patent/EP2266627B1/en not_active Expired - Lifetime
- 2000-08-25 AT AT00959442T patent/ATE478687T1/de active
- 2000-08-25 NZ NZ517942A patent/NZ517942A/en not_active IP Right Cessation
- 2000-08-25 ES ES00959442T patent/ES2358292T3/es not_active Expired - Lifetime
- 2000-08-25 ES ES10008602.4T patent/ES2542530T3/es not_active Expired - Lifetime
- 2000-08-25 DK DK00959442.5T patent/DK1210123T3/da active
- 2000-08-25 US US09/645,889 patent/US6479292B1/en not_active Expired - Lifetime
- 2000-08-25 PT PT00959442T patent/PT1210123E/pt unknown
- 2000-08-25 AU AU70767/00A patent/AU773242C/en not_active Expired
-
2002
- 2002-02-13 ZA ZA200201228A patent/ZA200201228B/en unknown
- 2002-11-12 US US10/292,856 patent/US7060500B2/en not_active Expired - Lifetime
-
2004
- 2004-08-19 AU AU2004205139A patent/AU2004205139B2/en not_active Expired
-
2012
- 2012-05-10 JP JP2012108528A patent/JP5813571B2/ja not_active Expired - Lifetime
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