DK1163257T3 - Fremgangsmåde til fremstilling af 4,4-dimethyl-3beta-hydroxypregna-8,14-dien-21-carboxylsyreestere og mellemprodukter i fremgangsmåden - Google Patents

Fremgangsmåde til fremstilling af 4,4-dimethyl-3beta-hydroxypregna-8,14-dien-21-carboxylsyreestere og mellemprodukter i fremgangsmåden

Info

Publication number: DK1163257T3
Authority: DK; Denmark
Prior art keywords: 3beta; dimethyl; hydroxypregna; diene; carboxylic acid
Prior art date: 1999-03-19

Application number

DK00914141T

Other languages

English (en)

Inventor

Jens Geisler

Eric Winter

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-19

Filing date

2000-03-16

Publication date

2003-03-03

2000-03-16 Application filed by Schering Ag filed Critical Schering Ag

2003-03-03 Application granted granted Critical

2003-03-03 Publication of DK1163257T3 publication Critical patent/DK1163257T3/da

Links

RSQQRYIOUVDIMD-DFGIHTTNSA-N 3-[(3S,10S,13R,17S)-3-hydroxy-4,4,10,13-tetramethyl-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-17-yl]propanoic acid Chemical class CC1(C)[C@@H](O)CC[C@]2(C)C(CC[C@]3(C4=CC[C@@H]3CCC(O)=O)C)=C4CCC21 RSQQRYIOUVDIMD-DFGIHTTNSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
LFQXEZVYNCBVDO-PBJLWWPKSA-N 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol Chemical compound C([C@@]12C)C[C@H](O)C(C)(C)[C@@H]1CCC1=C2CC[C@]2(C)[C@@H]([C@@H](CCC=C(C)C)C)CC=C21 LFQXEZVYNCBVDO-PBJLWWPKSA-N 0.000 abstract 1
239000013067 intermediate product Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK00914141T 1999-03-19 2000-03-16 Fremgangsmåde til fremstilling af 4,4-dimethyl-3beta-hydroxypregna-8,14-dien-21-carboxylsyreestere og mellemprodukter i fremgangsmåden DK1163257T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19914019A DE19914019C1 (de)	1999-03-19	1999-03-19	Verfahren zur Herstellung von 4,4-Dimethyl-3beta-hydroxypregna-8,14-dien-21-carbonsäureestern, deren Verwendung und Zwischenprodukte im Verfahren
PCT/EP2000/002323 WO2000056758A1 (de)	1999-03-19	2000-03-16	VERFAHREN ZUR HERSTELLUNG VON 4,4- DIMETHYL -3β- HYDROXYPREGNA -8,14-DIEN-21- CARBONSÄUREESTERN UND ZWISCHENPRODUKTE IM VERFAHREN

Publications (1)

Publication Number	Publication Date
DK1163257T3 true DK1163257T3 (da)	2003-03-03

Family

ID=7902688

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00914141T DK1163257T3 (da)	1999-03-19	2000-03-16	Fremgangsmåde til fremstilling af 4,4-dimethyl-3beta-hydroxypregna-8,14-dien-21-carboxylsyreestere og mellemprodukter i fremgangsmåden

Country Status (22)

Country	Link
US (1)	US6653491B1 (da)
EP (1)	EP1163257B1 (da)
JP (1)	JP2002540120A (da)
KR (1)	KR100594916B1 (da)
CN (1)	CN1152045C (da)
AT (1)	ATE227735T1 (da)
AU (1)	AU764034B2 (da)
BR (1)	BR0009116A (da)
CA (1)	CA2365083C (da)
CZ (1)	CZ20013277A3 (da)
DE (2)	DE19914019C1 (da)
DK (1)	DK1163257T3 (da)
ES (1)	ES2186638T3 (da)
HU (1)	HUP0200411A3 (da)
IL (1)	IL145017A (da)
MX (1)	MXPA01008816A (da)
NO (1)	NO320033B1 (da)
PL (1)	PL199151B1 (da)
PT (1)	PT1163257E (da)
SK (1)	SK283613B6 (da)
WO (1)	WO2000056758A1 (da)
ZA (1)	ZA200108570B (da)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5384313A (en) *	1993-11-24	1995-01-24	Wisconsin Alumni Research Foundation	21-norvitamin D compounds
DE19813962A1 (de) *	1998-03-28	1999-09-30	Bosch Gmbh Robert	Verfahren zur Datenübertragung in einem über eine Busleitung vernetzten Rückhaltesystem
DE19823677A1 (de) *	1998-04-09	1999-11-25	Schering Ag	Verfahren zur Herstellung von 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol und Zwischenprodukte im Verfahren (I)

1999
- 1999-03-19 DE DE19914019A patent/DE19914019C1/de not_active Expired - Fee Related
2000
- 2000-03-16 CN CNB008051631A patent/CN1152045C/zh not_active Expired - Fee Related
- 2000-03-16 DK DK00914141T patent/DK1163257T3/da active
- 2000-03-16 MX MXPA01008816A patent/MXPA01008816A/es unknown
- 2000-03-16 US US09/936,910 patent/US6653491B1/en not_active Expired - Fee Related
- 2000-03-16 WO PCT/EP2000/002323 patent/WO2000056758A1/de active IP Right Grant
- 2000-03-16 SK SK1325-2001A patent/SK283613B6/sk unknown
- 2000-03-16 EP EP00914141A patent/EP1163257B1/de not_active Expired - Lifetime
- 2000-03-16 DE DE50000755T patent/DE50000755D1/de not_active Expired - Fee Related
- 2000-03-16 ES ES00914141T patent/ES2186638T3/es not_active Expired - Lifetime
- 2000-03-16 JP JP2000606619A patent/JP2002540120A/ja active Pending
- 2000-03-16 BR BR0009116-2A patent/BR0009116A/pt not_active Application Discontinuation
- 2000-03-16 CA CA002365083A patent/CA2365083C/en not_active Expired - Fee Related
- 2000-03-16 PT PT00914141T patent/PT1163257E/pt unknown
- 2000-03-16 HU HU0200411A patent/HUP0200411A3/hu unknown
- 2000-03-16 AT AT00914141T patent/ATE227735T1/de not_active IP Right Cessation
- 2000-03-16 IL IL14501700A patent/IL145017A/xx unknown
- 2000-03-16 PL PL349712A patent/PL199151B1/pl unknown
- 2000-03-16 AU AU35566/00A patent/AU764034B2/en not_active Ceased
- 2000-03-16 KR KR1020017011874A patent/KR100594916B1/ko not_active IP Right Cessation
- 2000-03-16 CZ CZ20013277A patent/CZ20013277A3/cs unknown
2001
- 2001-09-18 NO NO20014530A patent/NO320033B1/no unknown
- 2001-10-18 ZA ZA200108570A patent/ZA200108570B/en unknown

Also Published As

Publication number	Publication date
PL199151B1 (pl)	2008-08-29
DE19914019C1 (de)	2000-09-28
JP2002540120A (ja)	2002-11-26
ATE227735T1 (de)	2002-11-15
CZ20013277A3 (cs)	2002-01-16
EP1163257B1 (de)	2002-11-13
US6653491B1 (en)	2003-11-25
WO2000056758A1 (de)	2000-09-28
SK283613B6 (sk)	2003-10-07
CN1344272A (zh)	2002-04-10
KR100594916B1 (ko)	2006-07-03
EP1163257A1 (de)	2001-12-19
KR20020002483A (ko)	2002-01-09
IL145017A (en)	2005-09-25
CN1152045C (zh)	2004-06-02
CA2365083C (en)	2006-12-19
HUP0200411A3 (en)	2003-05-28
BR0009116A (pt)	2001-12-18
PT1163257E (pt)	2003-03-31
NO20014530L (no)	2001-09-18
IL145017A0 (en)	2002-06-30
AU764034B2 (en)	2003-08-07
CA2365083A1 (en)	2000-09-28
SK13252001A3 (sk)	2002-02-05
NO320033B1 (no)	2005-10-10
ZA200108570B (en)	2003-01-20
AU3556600A (en)	2000-10-09
MXPA01008816A (es)	2002-05-14
DE50000755D1 (de)	2002-12-19
ES2186638T3 (es)	2003-05-16
NO20014530D0 (no)	2001-09-18
HUP0200411A2 (hu)	2002-07-29

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