DK1041985T3 - Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme - Google Patents

Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme

Info

Publication number
DK1041985T3
DK1041985T3 DK98963829T DK98963829T DK1041985T3 DK 1041985 T3 DK1041985 T3 DK 1041985T3 DK 98963829 T DK98963829 T DK 98963829T DK 98963829 T DK98963829 T DK 98963829T DK 1041985 T3 DK1041985 T3 DK 1041985T3
Authority
DK
Denmark
Prior art keywords
prophylactic
disorders
treatment
combination
antineoplastic drugs
Prior art date
Application number
DK98963829T
Other languages
English (en)
Inventor
Ronald J Doll
Ashit Ganguly
David L Cutler
Walter R Bishop
Joseph J Catino
Viyyoor Girijavallabhan
Paul Kirschmeier
Ming Liu
Loretta L Nielsen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27385940&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1041985(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK1041985T3 publication Critical patent/DK1041985T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98963829T 1997-12-22 1998-12-21 Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme DK1041985T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99602797A 1997-12-22 1997-12-22
US14352998A 1998-08-28 1998-08-28
US18196998A 1998-10-29 1998-10-29

Publications (1)

Publication Number Publication Date
DK1041985T3 true DK1041985T3 (da) 2006-06-19

Family

ID=27385940

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98963829T DK1041985T3 (da) 1997-12-22 1998-12-21 Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme

Country Status (25)

Country Link
EP (1) EP1041985B1 (da)
JP (1) JP4502503B2 (da)
KR (1) KR100700907B1 (da)
CN (1) CN1129431C (da)
AR (1) AR017440A1 (da)
AT (1) ATE317697T1 (da)
AU (1) AU756762B2 (da)
BR (1) BR9814419A (da)
CA (1) CA2315693C (da)
CL (1) CL2007001889A1 (da)
CO (1) CO5080764A1 (da)
CZ (1) CZ298511B6 (da)
DE (1) DE69833509T2 (da)
DK (1) DK1041985T3 (da)
ES (1) ES2255196T3 (da)
HU (1) HUP0102473A3 (da)
IL (1) IL136462A0 (da)
MY (1) MY137303A (da)
NO (1) NO326832B1 (da)
NZ (1) NZ504928A (da)
PE (1) PE20000042A1 (da)
PT (1) PT1041985E (da)
SK (1) SK285584B6 (da)
TW (1) TW581763B (da)
WO (1) WO1999032114A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787327B1 (fr) * 1998-12-21 2003-01-17 Aventis Pharma Sa Compositions contenant des inhibiteurs de farnesyle transferase
EP1430934A1 (fr) * 1999-11-09 2004-06-23 Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) Produit comprenant un inhibiteur de la transduction des signaux des protéines G hétérotrimetriques en association avec un autre agent anti-cancéreux pour une utilisation thérapeutique dans le traitement du cancer
AU2292801A (en) * 1999-12-22 2001-07-03 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Compositions and methods for treatment of breast cancer
WO2001064217A2 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Combinations of a farnesyl protein transferase inhibitor with nitrogen mustard or nitrosourea alkylating agents
US20030186925A1 (en) * 2000-02-29 2003-10-02 Palmer Peter Albert Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives
CA2397256A1 (en) * 2000-02-29 2001-09-07 Mary Ellen Margaret Rybak Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives
US20030027808A1 (en) * 2000-02-29 2003-02-06 Palmer Peter Albert Farnesyl protein transferase inhibitor combinations with platinum compounds
EP1263437A2 (en) * 2000-02-29 2002-12-11 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with vinca alkaloids
AU2001244167A1 (en) * 2000-02-29 2001-09-12 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
TWI310684B (en) 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
AU2002236813A1 (en) * 2001-01-22 2002-07-30 Schering Corporation Treatment of malaria with farnesyl protein transferase inhibitors
ES2318000T3 (es) * 2001-02-15 2009-05-01 Janssen Pharmaceutica Nv Combinaciones de inhibidores de la farnesil-protein-transferasa con agentes antiestrogenos.
BR0214564A (pt) * 2001-11-30 2004-11-09 Schering Corp Processos de tratamento de câncer utilizando um inibidor da fpt e agentes antineoplásicos
EP1453513A1 (en) * 2001-12-03 2004-09-08 Schering Corporation Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
CN105198758A (zh) * 2015-09-22 2015-12-30 湖南大学 一种高纯度(z)-他莫昔酚的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
WO1992011034A1 (en) * 1990-12-18 1992-07-09 The Wellcome Foundation Limited Agents for potentiating the effects of antitumor agents and combating multiple drug resistance
JP2767176B2 (ja) * 1992-12-15 1998-06-18 大塚製薬株式会社 抗癌剤
US5637688A (en) * 1994-12-13 1997-06-10 Eli Lilly And Company Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride
EP0856315B1 (en) * 1995-08-09 2005-08-24 Banyu Pharmaceutical Co., Ltd. Protein-farnesyltransferase inhibitors in combination with hmgcoa-reductase-inhibitors for the treatment of aids
PL185597B1 (pl) * 1995-12-22 2003-06-30 Schering Corp Tricykliczne amidy, środek farmaceutyczny i ich zastosowania
ES2448467T3 (es) * 1996-03-12 2014-03-14 Pg-Txl Company, L.P. Profármacos solubles en agua
JP2000507584A (ja) * 1996-04-03 2000-06-20 メルク エンド カンパニー インコーポレーテッド ファルネシル―タンパク質転移酵素の阻害剤
US20020034725A1 (en) * 1996-04-15 2002-03-21 W. Gillies Mckenna Sensitization of cells to radiation and and chemotherapy
CA2251955A1 (en) * 1996-04-18 1997-10-23 Nancy E. Kohl A method of treating cancer
EP0934270A1 (en) * 1996-05-30 1999-08-11 Merck & Co., Inc. A method of treating cancer
EP0967917B1 (en) * 1997-01-29 2005-11-30 Picker Medical Systems, Ltd. Predictive bolus tracking
KR100688409B1 (ko) * 1997-02-18 2007-03-02 캔지, 인크. 신생물에 대한 종양 억제 유전자 요법 및 화학 요법의 조합치료 방법

Also Published As

Publication number Publication date
ES2255196T3 (es) 2006-06-16
AU756762B2 (en) 2003-01-23
KR20010033452A (ko) 2001-04-25
SK8982000A3 (en) 2001-04-09
NO20003229L (no) 2000-08-22
CA2315693C (en) 2010-11-30
WO1999032114A1 (en) 1999-07-01
SK285584B6 (sk) 2007-04-05
EP1041985A1 (en) 2000-10-11
BR9814419A (pt) 2000-10-10
CA2315693A1 (en) 1999-07-01
TW581763B (en) 2004-04-01
CZ20002236A3 (cs) 2001-04-11
IL136462A0 (en) 2001-06-14
NO20003229D0 (no) 2000-06-21
CN1129431C (zh) 2003-12-03
AR017440A1 (es) 2001-09-05
EP1041985B1 (en) 2006-02-15
JP4502503B2 (ja) 2010-07-14
AU1907299A (en) 1999-07-12
PT1041985E (pt) 2006-07-31
KR100700907B1 (ko) 2007-03-29
HUP0102473A2 (hu) 2002-01-28
MY137303A (en) 2009-01-30
CN1284875A (zh) 2001-02-21
HUP0102473A3 (en) 2003-07-28
CO5080764A1 (es) 2001-09-25
CL2007001889A1 (es) 2008-01-11
NZ504928A (en) 2004-12-24
NO326832B1 (no) 2009-02-23
PE20000042A1 (es) 2000-02-17
JP2001526224A (ja) 2001-12-18
DE69833509D1 (de) 2006-04-20
CZ298511B6 (cs) 2007-10-24
ATE317697T1 (de) 2006-03-15
DE69833509T2 (de) 2006-10-26

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