DK1012293T3 - Forbindelser til immunterapi og diagnose af tuberkulose og fremgangsmåder til deres anvendelse - Google Patents

Forbindelser til immunterapi og diagnose af tuberkulose og fremgangsmåder til deres anvendelse

Info

Publication number
DK1012293T3
DK1012293T3 DK98924827T DK98924827T DK1012293T3 DK 1012293 T3 DK1012293 T3 DK 1012293T3 DK 98924827 T DK98924827 T DK 98924827T DK 98924827 T DK98924827 T DK 98924827T DK 1012293 T3 DK1012293 T3 DK 1012293T3
Authority
DK
Denmark
Prior art keywords
sequences
polypeptide
antigen
dna
given
Prior art date
Application number
DK98924827T
Other languages
English (en)
Inventor
Yasir A W Skeiky
Antonio Campos-Neto
Mark R Alderson
Davin C Dillon
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of DK1012293T3 publication Critical patent/DK1012293T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK98924827T 1997-05-20 1998-05-20 Forbindelser til immunterapi og diagnose af tuberkulose og fremgangsmåder til deres anvendelse DK1012293T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85938197A 1997-05-20 1997-05-20
US09/073,010 US6613881B1 (en) 1997-05-20 1998-05-05 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
PCT/US1998/010407 WO1998053075A2 (en) 1997-05-20 1998-05-20 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use

Publications (1)

Publication Number Publication Date
DK1012293T3 true DK1012293T3 (da) 2009-05-04

Family

ID=26754016

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98924827T DK1012293T3 (da) 1997-05-20 1998-05-20 Forbindelser til immunterapi og diagnose af tuberkulose og fremgangsmåder til deres anvendelse

Country Status (20)

Country Link
US (1) US6613881B1 (da)
EP (4) EP2270170B1 (da)
JP (4) JP4162155B2 (da)
KR (4) KR100909640B1 (da)
AT (1) ATE420180T1 (da)
AU (1) AU742751B2 (da)
BR (1) BR9809445A (da)
CA (2) CA2783134A1 (da)
CZ (2) CZ303194B6 (da)
DE (1) DE69840449D1 (da)
DK (1) DK1012293T3 (da)
ES (1) ES2321039T3 (da)
HU (1) HU226520B1 (da)
IL (2) IL133056A0 (da)
NO (4) NO324880B1 (da)
NZ (1) NZ501310A (da)
PL (1) PL191121B1 (da)
PT (1) PT1012293E (da)
TR (1) TR200000115T2 (da)
WO (1) WO1998053075A2 (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
EP0986572B2 (en) * 1997-06-06 2007-06-13 Dynavax Technologies Corporation Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
WO1999024577A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS)
CA2348475A1 (en) * 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
US20030027774A1 (en) * 1999-03-18 2003-02-06 Ronald C. Hendrickson Tuberculosis antigens and methods of use therefor
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
EP1200466A2 (en) * 1999-07-13 2002-05-02 Statens Serum Institut Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosisesat-6 gene family
WO2001024820A1 (en) * 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
WO2001062893A2 (en) 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
EP1278769A2 (en) * 2000-04-19 2003-01-29 Statens Serum Institut Tuberculosis antigens and methods of use thereof
ATE526994T1 (de) * 2000-06-20 2011-10-15 Corixa Corp Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten
AU2003213118A1 (en) * 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2005118884A1 (en) * 2004-05-28 2005-12-15 The United States Of America As Represented By The Secretary Of The Navy A method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
MX2007005256A (es) 2004-11-16 2008-03-11 Crucell Holland Bv Vacunas multivalentes que comprenden vectores virales recombinantes.
US8475803B2 (en) 2005-04-29 2013-07-02 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
EP1910410B1 (en) 2005-07-01 2011-10-26 Forsyth Dental Infirmary for Children Tuberculosis antigen detection assays and vaccines
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
EP2441469A1 (en) 2006-03-14 2012-04-18 Oregon Health and Science University Methods for producing an immune response to tuberculosis
ES2602430T3 (es) * 2008-07-25 2017-02-21 Glaxosmithkline Biologicals S.A. Polipéptidos, polinucleótidos y composiciones para uso en el tratamiento de tuberculosis latente
AU2009273133B2 (en) 2008-07-25 2014-06-05 Glaxo Group Limited Novel compositions and methods
EA201100070A1 (ru) 2008-07-25 2011-10-31 Глаксо Груп Лимитед Туберкулезный белок rv2386c, композиции и их применения
SI2528621T1 (sl) 2010-01-27 2017-01-31 Glaxosmithkline Biologicals S.A., Modificirani tuberkolozni antigeni
GB201012072D0 (en) * 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
RU2014101490A (ru) 2011-06-19 2015-07-27 Эйбоджен, Инк. Устройства, растворы и способы для сбора образцов
WO2016130543A1 (en) * 2015-02-09 2016-08-18 Abogen, Inc. Devices, solutions and methods for sample collection related applications, analysis and diagnosis

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4879213A (en) 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
US5330754A (en) 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
NZ278270A (en) * 1993-12-23 1997-12-19 Pastoral Agric Res Inst Nz Ltd Mycobacteria virulence factor proteins and coding sequences and their use
IE960132A1 (en) * 1995-03-13 1996-09-18 Astra Ab New DNA molecules
ATE324445T1 (de) 1995-09-01 2006-05-15 Corixa Corp Verbindungen und verfahren zur diagnose von tuberkulose
CA2684425A1 (en) 1995-09-01 1997-03-13 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
JP2001500383A (ja) * 1996-10-11 2001-01-16 コリックサ コーポレーション 結核診断用の化合物および方法

Also Published As

Publication number Publication date
KR20010012812A (ko) 2001-02-26
KR20060066139A (ko) 2006-06-15
EP2270170B1 (en) 2013-11-06
US6613881B1 (en) 2003-09-02
KR20070026886A (ko) 2007-03-08
NO20075902L (no) 2000-01-18
PL337330A1 (en) 2000-08-14
JP4759010B2 (ja) 2011-08-31
NO20075901L (no) 2000-01-18
IL133056A (en) 2010-11-30
NO20075900L (no) 2000-01-18
NO324880B1 (no) 2007-12-27
DE69840449D1 (de) 2009-02-26
AU7690798A (en) 1998-12-11
HUP0003402A3 (en) 2001-03-28
EP2248900B1 (en) 2012-07-18
KR100909640B1 (ko) 2009-07-27
JP2008253260A (ja) 2008-10-23
HUP0003402A2 (hu) 2000-12-28
NZ501310A (en) 2001-09-28
JP2002514084A (ja) 2002-05-14
PT1012293E (pt) 2009-04-08
JP2008283961A (ja) 2008-11-27
JP4759011B2 (ja) 2011-08-31
WO1998053075A3 (en) 1999-04-01
ATE420180T1 (de) 2009-01-15
CZ303194B6 (cs) 2012-05-23
KR100893118B1 (ko) 2009-04-14
JP4162155B2 (ja) 2008-10-08
ES2321039T3 (es) 2009-06-01
CZ300866B6 (cs) 2009-08-26
KR100924475B1 (ko) 2009-11-03
PL191121B1 (pl) 2006-03-31
AU742751B2 (en) 2002-01-10
EP2248900A1 (en) 2010-11-10
WO1998053075A2 (en) 1998-11-26
JP4764445B2 (ja) 2011-09-07
IL133056A0 (en) 2001-03-19
EP2172551A3 (en) 2010-11-10
EP2172551A2 (en) 2010-04-07
EP2270170A1 (en) 2011-01-05
BR9809445A (pt) 2000-06-13
CA2783134A1 (en) 1998-11-26
KR20080036663A (ko) 2008-04-28
CZ410099A3 (cs) 2000-05-17
HU226520B1 (en) 2009-03-30
JP2008245644A (ja) 2008-10-16
KR100652513B1 (ko) 2006-12-01
NO995689D0 (no) 1999-11-19
EP1012293A2 (en) 2000-06-28
EP1012293B1 (en) 2009-01-07
TR200000115T2 (tr) 2000-11-21
CA2290774A1 (en) 1998-11-26
NO995689L (no) 2000-01-18

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