US6727230B1
(en)
|
1994-03-25 |
2004-04-27 |
Coley Pharmaceutical Group, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
US20030026782A1
(en)
*
|
1995-02-07 |
2003-02-06 |
Arthur M. Krieg |
Immunomodulatory oligonucleotides
|
US7935675B1
(en)
*
|
1994-07-15 |
2011-05-03 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US6429199B1
(en)
*
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
US6207646B1
(en)
*
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
ES2283012T3
(es)
|
1996-01-04 |
2007-10-16 |
Novartis Vaccines And Diagnostics, Inc. |
Bacterioferritina de helicobacter pylori.
|
JP4111403B2
(ja)
*
|
1996-10-11 |
2008-07-02 |
ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア |
免疫刺激ポリヌクレオチド/免疫調節分子複合体
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
JP2001513776A
(ja)
|
1997-02-28 |
2001-09-04 |
ユニバーシティ オブ アイオワ リサーチ ファウンデーション |
LPS関連障害の処置における非メチル化CpGジヌクレオチドを含む核酸の使用
|
US6406705B1
(en)
*
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
JP4656675B2
(ja)
|
1997-05-14 |
2011-03-23 |
ユニバーシティー オブ ブリティッシュ コロンビア |
脂質小胞への荷電した治療剤の高率封入
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
DK1003850T3
(da)
*
|
1997-06-06 |
2009-09-07 |
Univ California |
Inhibitorer af DNA-immunstimulatorisk sekvensaktivitet
|
US6221882B1
(en)
*
|
1997-07-03 |
2001-04-24 |
University Of Iowa Research Foundation |
Methods for inhibiting immunostimulatory DNA associated responses
|
DE69837094T2
(de)
*
|
1997-09-05 |
2007-08-30 |
The Regents Of The University Of California, Oakland |
Verwendung von immunerregenden oligonukleotiden zur vorbeugung oder behandlung von asthma
|
BR9910643A
(pt)
*
|
1998-05-22 |
2001-10-30 |
Loeb Health Res Inst At The Ot |
Processos e produtos para a indução de imunidadede mucosa
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
JP4620251B2
(ja)
|
1998-08-10 |
2011-01-26 |
アンチジェニックス・インコーポレイテッド |
Cpgおよびサポニンアジュバントの組成物並びにその方法
|
AU6425999A
(en)
*
|
1998-10-09 |
2000-05-01 |
Dynavax Technologies Corporation |
Anti hiv compositions comprising immunostimulatory polynucleotides and hiv antigens
|
JP4812942B2
(ja)
*
|
1999-02-26 |
2011-11-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強
|
WO2000050006A2
(en)
|
1999-02-26 |
2000-08-31 |
Chiron Corporation |
Microemulsions with adsorbed macromoelecules and microparticles
|
GB2348132B
(en)
*
|
1999-03-02 |
2004-08-04 |
Nedaa Abdul-Ghani Nasif |
Asthma/allergy therapy that targets t-lymphocytes and/or eosinophils
|
WO2000054803A2
(en)
*
|
1999-03-16 |
2000-09-21 |
Panacea Pharmaceuticals, Llc |
Immunostimulatory nucleic acids and antigens
|
FR2790955B1
(fr)
*
|
1999-03-19 |
2003-01-17 |
Assist Publ Hopitaux De Paris |
Utilisation d'oligonucleotides stabilises comme principe actif antitumoral
|
US6977245B2
(en)
|
1999-04-12 |
2005-12-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
EP1176966B1
(en)
|
1999-04-12 |
2013-04-03 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Oligodeoxynucleotide and its use to induce an immune response
|
US6558670B1
(en)
|
1999-04-19 |
2003-05-06 |
Smithkline Beechman Biologicals S.A. |
Vaccine adjuvants
|
PL203951B1
(pl)
|
1999-04-19 |
2009-11-30 |
Smithkline Beecham Biolog |
Kompozycja adiuwantowa, kompozycja szczepionki oraz sposób jej wytwarzania, szczepionka oraz zastosowanie
|
US6737066B1
(en)
|
1999-05-06 |
2004-05-18 |
The Immune Response Corporation |
HIV immunogenic compositions and methods
|
AU4992900A
(en)
*
|
1999-05-06 |
2000-11-21 |
Immune Response Corporation, The |
Hiv immunogenic compositions and methods
|
CA2380947C
(en)
*
|
1999-08-19 |
2011-11-01 |
Dynavax Technologies Corporation |
Methods of modulating an immune response using immunostimulatory sequences and compositions for use therein
|
IL148359A0
(en)
*
|
1999-08-27 |
2002-09-12 |
Inex Pharmaceuticals Corp |
Pharmaceutical compositions containing an oligodeoxynucleotide
|
US6949520B1
(en)
|
1999-09-27 |
2005-09-27 |
Coley Pharmaceutical Group, Inc. |
Methods related to immunostimulatory nucleic acid-induced interferon
|
EP2275551B1
(en)
|
1999-10-29 |
2015-04-08 |
Novartis Vaccines and Diagnostics S.r.l. |
Neisserial antigenic peptides
|
US7223398B1
(en)
|
1999-11-15 |
2007-05-29 |
Dynavax Technologies Corporation |
Immunomodulatory compositions containing an immunostimulatory sequence linked to antigen and methods of use thereof
|
ATE378348T1
(de)
|
2000-01-14 |
2007-11-15 |
Us Health |
Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion
|
WO2001095935A1
(en)
*
|
2000-01-20 |
2001-12-20 |
Ottawa Health Research Institute |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
US20040131628A1
(en)
*
|
2000-03-08 |
2004-07-08 |
Bratzler Robert L. |
Nucleic acids for the treatment of disorders associated with microorganisms
|
US20010046967A1
(en)
|
2000-03-10 |
2001-11-29 |
Gary Van Nest |
Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide
|
US20020028784A1
(en)
*
|
2000-03-10 |
2002-03-07 |
Nest Gary Van |
Methods of preventing and treating viral infections using immunomodulatory polynucleotide sequences
|
US20020098199A1
(en)
*
|
2000-03-10 |
2002-07-25 |
Gary Van Nest |
Methods of suppressing hepatitis virus infection using immunomodulatory polynucleotide sequences
|
US20020107212A1
(en)
*
|
2000-03-10 |
2002-08-08 |
Nest Gary Van |
Methods of reducing papillomavirus infection using immunomodulatory polynucleotide sequences
|
US7129222B2
(en)
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
US7157437B2
(en)
|
2000-03-10 |
2007-01-02 |
Dynavax Technologies Corporation |
Methods of ameliorating symptoms of herpes infection using immunomodulatory polynucleotide sequences
|
SI1296713T1
(en)
|
2000-06-08 |
2004-02-29 |
Intercell Biomedizinische Forschungs- |
Immunostimulatory oligodeoxynucleotides
|
AU2001282475A1
(en)
*
|
2000-08-25 |
2002-03-04 |
Yeda Research And Development Co. Ltd. |
Methods of treatment or prevention of autoimmune diseases with CpG-containing polynucleotide
|
EP2277894A1
(en)
|
2000-10-27 |
2011-01-26 |
Novartis Vaccines and Diagnostics S.r.l. |
Nucleic acids and proteins from streptococcus groups A & B
|
DE60134421D1
(de)
*
|
2000-12-08 |
2008-07-24 |
Coley Pharmaceuticals Gmbh |
Cpg-artige nukleinsäuren und verfahren zu ihrer verwendung
|
DE60142410D1
(de)
*
|
2000-12-27 |
2010-07-29 |
Dynavax Tech Corp |
Immunomodulatorische polynukleotide und verfahren zur deren verwendung
|
JP2005501004A
(ja)
|
2001-05-21 |
2005-01-13 |
インターツェル・アクチェンゲゼルシャフト |
核酸の安定化法
|
DE50214200D1
(de)
|
2001-06-05 |
2010-03-25 |
Curevac Gmbh |
Stabilisierte Tumorantigen-mRNA mit erhöhtem G/C-Gehalt
|
GB0115176D0
(en)
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
US20030199466A1
(en)
|
2001-06-21 |
2003-10-23 |
Fearon Karen L. |
Chimeric immunomodulatory compounds and methods of using the same - ll
|
GB0118249D0
(en)
|
2001-07-26 |
2001-09-19 |
Chiron Spa |
Histidine vaccines
|
GB0121591D0
(en)
|
2001-09-06 |
2001-10-24 |
Chiron Spa |
Hybrid and tandem expression of neisserial proteins
|
US7666674B2
(en)
|
2001-07-27 |
2010-02-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
|
US20030148316A1
(en)
*
|
2001-08-01 |
2003-08-07 |
Lipford Grayson B. |
Methods and compositions relating to plasmacytoid dendritic cells
|
JP4607452B2
(ja)
|
2001-08-07 |
2011-01-05 |
ダイナバックス テクノロジーズ コーポレイション |
免疫調節性組成物、製剤およびその使用方法
|
WO2003020884A2
(en)
*
|
2001-08-14 |
2003-03-13 |
The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services |
Method for rapid generation of mature dendritic cells
|
DK1450856T3
(da)
|
2001-09-14 |
2010-05-31 |
Cytos Biotechnology Ag |
Pakning af immunstimulatorisk CpG i virus-lignende partilker, fremgangsmåde og anvendelse
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
EP2301553A1
(en)
|
2001-11-21 |
2011-03-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
Polynucleotide therapy
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
WO2003054161A2
(en)
*
|
2001-12-20 |
2003-07-03 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS
|
US8466116B2
(en)
|
2001-12-20 |
2013-06-18 |
The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of CpG oligodeoxynucleotides to induce epithelial cell growth
|
JP4646516B2
(ja)
|
2002-02-20 |
2011-03-09 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
吸着したポリペプチド含有分子を有する微粒子
|
CA2388049A1
(en)
*
|
2002-05-30 |
2003-11-30 |
Immunotech S.A. |
Immunostimulatory oligonucleotides and uses thereof
|
US20040009949A1
(en)
*
|
2002-06-05 |
2004-01-15 |
Coley Pharmaceutical Group, Inc. |
Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory CpG nucleic acids
|
US7807803B2
(en)
|
2002-07-03 |
2010-10-05 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
US20040053880A1
(en)
|
2002-07-03 |
2004-03-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
AU2003247880B2
(en)
*
|
2002-07-03 |
2010-09-02 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
JP4806187B2
(ja)
*
|
2002-07-15 |
2011-11-02 |
ギリード・サイエンシズ・インコーポレーテッド |
B型肝炎ウイルスの治療のためのl−fmauとの併用療法
|
CA2494911A1
(en)
|
2002-08-12 |
2004-02-19 |
Dynavax Technologies Corporation |
Immunomodulatory compositions, methods of making, and methods of use thereof
|
GB0220194D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Improved vesicles
|
US8263091B2
(en)
*
|
2002-09-18 |
2012-09-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides
|
EP2241325B1
(en)
|
2002-10-29 |
2012-02-08 |
Coley Pharmaceutical Group, Inc. |
Use of CPG oligonucleotides in the treatment of hepatitis C virus infection
|
AU2003304107B2
(en)
*
|
2002-11-01 |
2008-05-15 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of preventing infections from bioterrorism agents with immunostimulatory CpG oligonucleotides
|
US20070059329A1
(en)
|
2002-11-15 |
2007-03-15 |
Nathalie Norais |
Unexpected surface proteins in meningococcus
|
EP2298360A3
(en)
|
2002-11-21 |
2011-07-13 |
Bayhill Therapeutics, Inc. |
Methods and immune modulatory nucleic acid compositions for preventing and treating disease
|
GB0227346D0
(en)
|
2002-11-22 |
2002-12-31 |
Chiron Spa |
741
|
WO2004053104A2
(en)
|
2002-12-11 |
2004-06-24 |
Coley Pharmaceutical Group, Inc. |
5’ cpg nucleic acids and methods of use
|
KR101309501B1
(ko)
|
2002-12-23 |
2013-09-24 |
다이나박스 테크놀로지 코퍼레이션 |
면역자극성 서열 올리고뉴클레오타이드 및 이의 이용방법
|
US7625872B2
(en)
|
2002-12-23 |
2009-12-01 |
Dynavax Technologies Corporation |
Branched immunomodulatory compounds and methods of using the same
|
US8158768B2
(en)
|
2002-12-23 |
2012-04-17 |
Dynavax Technologies Corporation |
Immunostimulatory sequence oligonucleotides and methods of using the same
|
EP2263687B1
(en)
|
2002-12-27 |
2015-03-25 |
Novartis Vaccines and Diagnostics, Inc. |
Immunogenic compositions containing phospholipid
|
ES2391770T3
(es)
|
2003-01-21 |
2012-11-29 |
Novartis Vaccines And Diagnostics, Inc. |
Uso de compuestos de triptantrina para la potenciación inmune
|
US8877204B2
(en)
|
2003-02-20 |
2014-11-04 |
University Of Connecticut Health Center |
Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes
|
US7537767B2
(en)
|
2003-03-26 |
2009-05-26 |
Cytis Biotechnology Ag |
Melan-A- carrier conjugates
|
ZA200507063B
(en)
|
2003-03-26 |
2007-03-28 |
Cytos Biotechnology Ag |
Packaging of immunostimulatory oligonucleotides into virus-like particles: Method of preparation and use
|
US7893096B2
(en)
|
2003-03-28 |
2011-02-22 |
Novartis Vaccines And Diagnostics, Inc. |
Use of small molecule compounds for immunopotentiation
|
WO2004087203A2
(en)
*
|
2003-04-02 |
2004-10-14 |
Coley Pharmaceutical Group, Ltd. |
Immunostimulatory nucleic acid oil-in-water formulations for topical application
|
CN1798563A
(zh)
*
|
2003-05-15 |
2006-07-05 |
独立行政法人科学技术振兴机构 |
免疫刺激剂
|
JP2007537985A
(ja)
*
|
2003-05-15 |
2007-12-27 |
ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニバーシティー |
免疫調節ペプチド
|
CN1798548B
(zh)
|
2003-06-02 |
2010-05-05 |
诺华疫苗和诊断公司 |
基于含吸附类毒素和含多糖抗原微粒体的免疫原性组合物
|
US20060035242A1
(en)
|
2004-08-13 |
2006-02-16 |
Michelitsch Melissa D |
Prion-specific peptide reagents
|
US20050239733A1
(en)
*
|
2003-10-31 |
2005-10-27 |
Coley Pharmaceutical Gmbh |
Sequence requirements for inhibitory oligonucleotides
|
JP4817599B2
(ja)
*
|
2003-12-25 |
2011-11-16 |
独立行政法人科学技術振興機構 |
免疫活性増強剤とこれを用いた免疫活性の増強方法
|
JP3976742B2
(ja)
|
2004-02-27 |
2007-09-19 |
江守商事株式会社 |
インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド
|
TWI235440B
(en)
*
|
2004-03-31 |
2005-07-01 |
Advanced Semiconductor Eng |
Method for making leadless semiconductor package
|
US20110104186A1
(en)
|
2004-06-24 |
2011-05-05 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
CA2571421A1
(en)
|
2004-06-24 |
2006-01-05 |
Nicholas Valiante |
Compounds for immunopotentiation
|
KR101268877B1
(ko)
|
2004-09-01 |
2013-05-31 |
다이나박스 테크놀로지 코퍼레이션 |
선천성 면역반응 및 자가면역의 억제를 위한 방법 및조성물
|
JP2008000001A
(ja)
*
|
2004-09-30 |
2008-01-10 |
Osaka Univ |
免疫刺激オリゴヌクレオチドおよびその医薬用途
|
US20060135906A1
(en)
*
|
2004-11-16 |
2006-06-22 |
Akihiko Matsumura |
Iontophoretic device and method for administering immune response-enhancing agents and compositions
|
WO2006066003A2
(en)
*
|
2004-12-17 |
2006-06-22 |
Dynavax Technologies Corporation |
Methods and compositions for induction or promotion of immune tolerance
|
EP2433647A3
(en)
|
2005-01-27 |
2012-06-06 |
Children's Hospital & Research Center at Oakland |
GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
|
AU2006216493A1
(en)
*
|
2005-02-24 |
2006-08-31 |
Coley Pharmaceutical Gmbh |
Immunostimulatory oligonucleotides
|
KR20070110901A
(ko)
|
2005-03-04 |
2007-11-20 |
다이나박스 테크놀로지 코퍼레이션 |
항원에 콘쥬게이트되고 버퍼 조건 및 추가의 부형제들에의해 안정화된 면역자극성 서열(iss)을 갖는올리고뉴클레오티드를 포함하는 백신
|
EP1868628B1
(en)
|
2005-04-08 |
2014-06-11 |
Chimerix, Inc. |
Compounds, compositions and methods for the treatment of poxvirus infections
|
EP1865967A4
(en)
*
|
2005-04-08 |
2011-02-09 |
Chimerix Inc |
COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES
|
EP1928539A1
(en)
*
|
2005-09-30 |
2008-06-11 |
Tti Ellebeau, Inc. |
Functionalized microneedles transdermal drug delivery systems, devices, and methods
|
KR20080066712A
(ko)
*
|
2005-09-30 |
2008-07-16 |
티티아이 엘뷰 가부시키가이샤 |
관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
|
KR20080080087A
(ko)
*
|
2005-09-30 |
2008-09-02 |
티티아이 엘뷰 가부시키가이샤 |
신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법
|
AU2006325225B2
(en)
|
2005-12-14 |
2013-07-04 |
Cytos Biotechnology Ag |
Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
|
WO2007089871A2
(en)
*
|
2006-02-01 |
2007-08-09 |
The Johns Hopkins University |
Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders
|
CA2642152C
(en)
*
|
2006-02-15 |
2016-11-01 |
Coley Pharmaceutical Gmbh |
Compositions and methods for oligonucleotide formulations
|
ES2534332T3
(es)
|
2006-03-07 |
2015-04-21 |
Vaxinnate Corporation |
Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
|
PL2034015T3
(pl)
|
2006-05-31 |
2012-11-30 |
Toray Industries |
Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne
|
WO2007144150A1
(en)
|
2006-06-12 |
2007-12-21 |
Cytos Biotechnology Ag |
Processes for packaging oligonucleotides into virus-like particles of rna bacteriophages
|
JP2009540016A
(ja)
*
|
2006-06-13 |
2009-11-19 |
ベイヒル セラピューティクス インコーポレーティッド |
疾患を予防および処置するための方法および免疫調節核酸組成物
|
DE102006035618A1
(de)
*
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
|
AU2007280690C1
(en)
|
2006-07-31 |
2012-08-23 |
Curevac Gmbh |
Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
|
CN101636495A
(zh)
|
2006-11-09 |
2010-01-27 |
戴纳瓦克斯技术公司 |
使用免疫刺激性寡核苷酸进行长期的疾病修饰
|
US20090123467A1
(en)
*
|
2007-07-31 |
2009-05-14 |
The Johns Hopkins University |
Polypeptide-Nucleic Acid Conjugate for Immunoprophylaxis or Immunotherapy for Neoplastic or Infectious Disorders
|
EP2173912A4
(en)
*
|
2007-08-01 |
2013-03-20 |
Idera Pharmaceuticals Inc |
NEW SYNTHETIC AGONISTS OF TLR9
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
JP5749492B2
(ja)
*
|
2007-10-26 |
2015-07-15 |
ダイナバックス テクノロジーズ コーポレイション |
免疫応答と自己免疫を阻害する方法及び組成物
|
CN103172750B
(zh)
|
2007-11-01 |
2014-12-10 |
安斯泰来制药有限公司 |
免疫抑制性多肽与核酸
|
JP2011506334A
(ja)
|
2007-12-07 |
2011-03-03 |
ノバルティス アーゲー |
免疫応答を誘導するための組成物
|
CA2713105C
(en)
*
|
2008-01-25 |
2016-06-07 |
Chimerix, Inc. |
Methods of treating viral infections
|
EP2265640B1
(en)
|
2008-03-10 |
2015-11-04 |
Children's Hospital & Research Center at Oakland |
Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use
|
AU2009236585B2
(en)
|
2008-04-18 |
2013-03-07 |
Vaxinnate Corporation |
Deletion mutants of flagellin and methods of use
|
EP2300102B1
(en)
|
2008-05-15 |
2014-01-08 |
Dynavax Technologies Corporation |
Immunostimulatory sequences containing CpG for use in the treatment of allergic rhinitis
|
GB0809476D0
(en)
*
|
2008-05-23 |
2008-07-02 |
Cambridge Entpr Ltd |
Treatment of neurodegenerative disorders
|
DK3056214T3
(da)
|
2008-06-27 |
2019-05-13 |
Zoetis Services Llc |
Hidtil ukendte adjuvanssammensætninger
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
CN102245198B
(zh)
|
2008-12-09 |
2016-08-17 |
辉瑞疫苗有限责任公司 |
IgE CH3肽疫苗
|
CA2748788C
(en)
|
2009-01-05 |
2021-02-09 |
Epitogenesis Inc. |
The use of a composition comprising mustard oil, catechin, and vitamin a for modulating an immune response
|
JP5759445B2
(ja)
|
2009-03-25 |
2015-08-05 |
ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム |
病原体に対する哺乳類先天性免疫抵抗性の刺激のための組成物
|
WO2011011519A1
(en)
|
2009-07-21 |
2011-01-27 |
Chimerix, Inc. |
Compounds, compositions and methods for treating ocular conditions
|
KR20130127547A
(ko)
|
2009-07-30 |
2013-11-22 |
화이자 백신스 엘엘씨 |
항원성 타우 펩타이드 및 이의 용도
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
SG178447A1
(en)
|
2009-09-03 |
2012-03-29 |
Pfizer Vaccines Llc |
Pcsk9 vaccine
|
EP2496944A2
(en)
|
2009-11-05 |
2012-09-12 |
Novartis AG |
Biomarkers predictive of progression of fibrosis
|
WO2011077309A2
(en)
|
2009-12-22 |
2011-06-30 |
Pfizer Vaccines Llc |
Vaccine compositions
|
AU2011216243B2
(en)
|
2010-02-12 |
2015-07-09 |
Chimerix, Inc. |
Nucleoside phosphonate salts
|
JP2013521002A
(ja)
|
2010-03-05 |
2013-06-10 |
プレジデント アンド フェロウズ オブ ハーバード カレッジ |
誘導樹状細胞組成物及びその使用
|
CN105315351A
(zh)
|
2010-03-30 |
2016-02-10 |
奥克兰儿童医院及研究中心 |
改性的h因子结合蛋白(fhbp)及其使用方法
|
EP2563367A4
(en)
|
2010-04-26 |
2013-12-04 |
Chimerix Inc |
METHODS OF TREATING RETROVIRAL INFECTIONS AND ASSOCIATED DOSAGE REGIMES
|
EP2575868A1
(en)
|
2010-06-07 |
2013-04-10 |
Pfizer Vaccines LLC |
Ige ch3 peptide vaccine
|
US8895017B2
(en)
|
2010-06-07 |
2014-11-25 |
Pfizer Inc. |
HER-2 peptides and vaccines
|
AU2011268211B2
(en)
|
2010-06-16 |
2015-07-16 |
Dynavax Technologies Corporation |
Methods of treatment using TLR7 and/or TLR9 inhibitors
|
US8968746B2
(en)
|
2010-07-30 |
2015-03-03 |
Curevac Gmbh |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
PL3590949T3
(pl)
|
2010-10-01 |
2022-08-29 |
Modernatx, Inc. |
Kwasy rybonukleinowe zawierające n1-metylo-pseudouracyle i ich zastosowania
|
WO2012131504A1
(en)
|
2011-03-02 |
2012-10-04 |
Pfizer Inc. |
Pcsk9 vaccine
|
AU2012236099A1
(en)
|
2011-03-31 |
2013-10-03 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
AU2012318752B2
(en)
|
2011-10-03 |
2017-08-31 |
Modernatx, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
LT2791160T
(lt)
|
2011-12-16 |
2022-06-10 |
Modernatx, Inc. |
Modifikuotos mrnr sudėtys
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
AU2013243951A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of secreted proteins
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
EP2844282B1
(en)
|
2012-05-04 |
2019-06-12 |
Pfizer Inc |
Prostate-associated antigens and vaccine-based immunotherapy regimens
|
US9868955B2
(en)
|
2012-09-29 |
2018-01-16 |
Dynavax Technologies Corporation |
Human toll-like receptor inhibitors and methods of use thereof
|
US9228184B2
(en)
|
2012-09-29 |
2016-01-05 |
Dynavax Technologies Corporation |
Human toll-like receptor inhibitors and methods of use thereof
|
JP6144355B2
(ja)
|
2012-11-26 |
2017-06-07 |
モデルナティエックス インコーポレイテッドModernaTX,Inc. |
化学修飾mRNA
|
JP2016507520A
(ja)
|
2013-01-23 |
2016-03-10 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
安定化されたb型肝炎コアポリペプチド
|
WO2014153209A1
(en)
|
2013-03-14 |
2014-09-25 |
Andes Biotechnologies S.A. |
Antisense oligonucletotides for treatment of cancer stem cells
|
CN105283466A
(zh)
|
2013-03-14 |
2016-01-27 |
安第斯生物技术股份有限公司 |
用于检测和治疗多发性骨髓瘤的方法
|
WO2014153087A1
(en)
|
2013-03-14 |
2014-09-25 |
President And Fellows Of Harvard College |
Nanoparticle-based compositions
|
WO2014151994A1
(en)
|
2013-03-15 |
2014-09-25 |
Kambiz Shekdar |
Genome editing using effector oligonucleotides for therapeutic treatment
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
EP2996718B1
(en)
|
2013-05-15 |
2020-01-15 |
The Governors of the University of Alberta |
E1e2 hcv vaccines and methods of use
|
AU2014310934B2
(en)
|
2013-08-21 |
2019-09-12 |
CureVac SE |
Respiratory syncytial virus (RSV) vaccine
|
KR20190009840A
(ko)
|
2013-09-19 |
2019-01-29 |
조에티스 서비시즈 엘엘씨 |
유성 아쥬반트
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
EA201690675A1
(ru)
|
2013-10-03 |
2016-08-31 |
Модерна Терапьютикс, Инк. |
Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности
|
WO2015062738A1
(en)
|
2013-11-01 |
2015-05-07 |
Curevac Gmbh |
Modified rna with decreased immunostimulatory properties
|
KR102006527B1
(ko)
|
2013-11-01 |
2019-08-02 |
화이자 인코포레이티드 |
전립선-연관 항원의 발현을 위한 벡터
|
WO2015123291A1
(en)
|
2014-02-11 |
2015-08-20 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Pcsk9 vaccine and methods of using the same
|
CA2936286A1
(en)
|
2014-04-01 |
2015-10-08 |
Curevac Ag |
Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant
|
WO2016044839A2
(en)
|
2014-09-19 |
2016-03-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
HRP20230752T1
(hr)
|
2015-01-16 |
2023-10-27 |
Zoetis Services Llc |
Cjepivo protiv slinavke i šapa
|
EP3892284B1
(en)
|
2015-05-29 |
2024-05-22 |
Merck Sharp & Dohme LLC |
Combination of a pd-1 antagonist and a cpg-c type oligonucleotide for treating cancer
|
DK3405212T3
(da)
|
2016-01-19 |
2020-08-24 |
Pfizer |
Cancervacciner
|
CN114807152A
(zh)
*
|
2016-06-08 |
2022-07-29 |
哈佛学院院长及董事 |
工程化病毒载体减少了炎症和免疫反应的诱导
|
CA3043480A1
(en)
|
2016-11-09 |
2018-05-17 |
The Board Of Regents Of The University Of Texas System |
Methods and compositions for adaptive immune modulation
|
CN111511918A
(zh)
*
|
2017-11-08 |
2020-08-07 |
哈佛学院院长及董事 |
抑制病毒载体诱导的炎症反应的组合物和方法
|
WO2019173438A1
(en)
|
2018-03-06 |
2019-09-12 |
Stc. Unm |
Compositions and methods for reducing serum triglycerides
|
US11987795B2
(en)
|
2020-11-24 |
2024-05-21 |
The Broad Institute, Inc. |
Methods of modulating SLC7A11 pre-mRNA transcripts for diseases and conditions associated with expression of SLC7A11
|
WO2022147373A1
(en)
|
2020-12-31 |
2022-07-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-guided pcsk9-mimicking immunogens lacking 9-residue sequence overlap with human proteins
|
US20240159738A1
(en)
|
2021-03-16 |
2024-05-16 |
Osaka University |
Novel medical technique using follicular t-cells
|
JPWO2022196699A1
(da)
|
2021-03-16 |
2022-09-22 |
|
|
WO2023081486A1
(en)
|
2021-11-08 |
2023-05-11 |
Nurix Therapeutics, Inc. |
Toll-like receptor therapy combinations with cbl-b inhibitor compounds
|