DK0991705T3 - Åbenporede, bionedbrydelige matricer - Google Patents
Åbenporede, bionedbrydelige matricerInfo
- Publication number
- DK0991705T3 DK0991705T3 DK98913264T DK98913264T DK0991705T3 DK 0991705 T3 DK0991705 T3 DK 0991705T3 DK 98913264 T DK98913264 T DK 98913264T DK 98913264 T DK98913264 T DK 98913264T DK 0991705 T3 DK0991705 T3 DK 0991705T3
- Authority
- DK
- Denmark
- Prior art keywords
- traced
- open
- porous polymer
- biodegradable matrices
- directed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/26—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C44/00—Shaping by internal pressure generated in the material, e.g. swelling or foaming ; Producing porous or cellular expanded plastics articles
- B29C44/34—Auxiliary operations
- B29C44/3442—Mixing, kneading or conveying the foamable material
- B29C44/3446—Feeding the blowing agent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
- B29C67/20—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 for porous or cellular articles, e.g. of foam plastics, coarse-pored
- B29C67/202—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 for porous or cellular articles, e.g. of foam plastics, coarse-pored comprising elimination of a solid or a liquid ingredient
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
- C08J9/12—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
- C08J9/122—Hydrogen, oxygen, CO2, nitrogen or noble gases
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/16—Making expandable particles
- C08J9/18—Making expandable particles by impregnating polymer particles with the blowing agent
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2201/00—Foams characterised by the foaming process
- C08J2201/02—Foams characterised by the foaming process characterised by mechanical pre- or post-treatments
- C08J2201/032—Impregnation of a formed object with a gas
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2201/00—Foams characterised by the foaming process
- C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
- C08J2201/044—Elimination of an inorganic solid phase
- C08J2201/0444—Salts
- C08J2201/0446—Elimination of NaCl only
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2203/00—Foams characterized by the expanding agent
- C08J2203/06—CO2, N2 or noble gases
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2205/00—Foams characterised by their properties
- C08J2205/04—Foams characterised by their properties characterised by the foam pores
- C08J2205/05—Open cells, i.e. more than 50% of the pores are open
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mechanical Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Biological Depolymerization Polymers (AREA)
- Lubricants (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4219897P | 1997-03-31 | 1997-03-31 | |
PCT/US1998/006188 WO1998044027A1 (en) | 1997-03-31 | 1998-03-31 | Open pore biodegradable matrices |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0991705T3 true DK0991705T3 (da) | 2004-01-12 |
Family
ID=21920588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98913264T DK0991705T3 (da) | 1997-03-31 | 1998-03-31 | Åbenporede, bionedbrydelige matricer |
Country Status (10)
Country | Link |
---|---|
US (2) | US6281256B1 (da) |
EP (1) | EP0991705B1 (da) |
JP (1) | JP4085341B2 (da) |
AT (1) | ATE249491T1 (da) |
AU (1) | AU736102B2 (da) |
CA (1) | CA2285329A1 (da) |
DE (1) | DE69818052T2 (da) |
DK (1) | DK0991705T3 (da) |
ES (1) | ES2205467T3 (da) |
WO (1) | WO1998044027A1 (da) |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL118376A0 (en) * | 1996-05-22 | 1996-09-12 | Univ Ben Gurion | Polysaccharide sponges for cell culture and transplantation |
JP4085341B2 (ja) * | 1997-03-31 | 2008-05-14 | ザ、リージエンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン | 開いたポアの生分解性マトリックス |
WO1999058656A2 (en) * | 1998-05-13 | 1999-11-18 | The Regents Of The University Of Michigan | Sustained dna delivery from structural matrices |
US7427602B1 (en) * | 1998-05-13 | 2008-09-23 | The Regents Of The University Of Michigan | Sustained DNA delivery from structural matrices |
EP1277482A3 (en) * | 1999-03-19 | 2005-05-11 | The Regents of The University of Michigan | Mineralization and cellular patterning on biomaterial surfaces |
AU4173000A (en) | 1999-03-19 | 2000-10-09 | Regents Of The University Of Michigan, The | Mineralization and cellular patterning on biomaterial surfaces |
US6767928B1 (en) | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
US6103255A (en) | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
ATE266435T1 (de) * | 1999-04-16 | 2004-05-15 | Univ Rutgers | Poröse polymere stützgewebe für gewebetechnologie |
WO2001035932A2 (en) * | 1999-11-18 | 2001-05-25 | The Regents Of The University Of Michigan | Sustained drug delivery from structural matrices |
US6702849B1 (en) * | 1999-12-13 | 2004-03-09 | Advanced Cardiovascular Systems, Inc. | Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers |
IT1307829B1 (it) * | 1999-12-21 | 2001-11-19 | Consiglio Nazionale Ricerche | Protesi dentale con mezzi per il rilascio di farmaci o fattorispecifici atti ad impedire l'insorgenza di infezioni e/o promuovere |
KR100355563B1 (ko) * | 2000-06-23 | 2002-10-11 | 주식회사 바이오메드랩 | 비등성 혼합물을 이용한 조직공학용 생분해성의 다공성고분자 지지체 및 그의 제조방법 |
US7198641B2 (en) * | 2000-08-08 | 2007-04-03 | Aderans Research Institute, Inc. | Scaffolds for tissue engineered hair |
US7709029B2 (en) * | 2001-01-24 | 2010-05-04 | Ada Foundation | Calcium-containing restoration materials |
US6793725B2 (en) | 2001-01-24 | 2004-09-21 | Ada Foundation | Premixed calcium phosphate cement pastes |
US7294187B2 (en) * | 2001-01-24 | 2007-11-13 | Ada Foundation | Rapid-hardening calcium phosphate cement compositions |
JP4731044B2 (ja) * | 2001-05-22 | 2011-07-20 | 独立行政法人理化学研究所 | 延伸フィルムおよびそれを用いた細胞培養基材 |
EP1446445A4 (en) * | 2001-09-21 | 2007-04-04 | Stryker Corp | PORENCIL FOR ORTHOPEDIC CEMENT |
US7105580B2 (en) * | 2001-12-06 | 2006-09-12 | University Of Washington | Porous structures useful for growing living tissue, and methods of manufacture |
US6955716B2 (en) | 2002-03-01 | 2005-10-18 | American Dental Association Foundation | Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates |
US9445901B2 (en) * | 2003-03-12 | 2016-09-20 | Deger C. Tunc | Prosthesis with sustained release analgesic |
US20060076295A1 (en) | 2004-03-15 | 2006-04-13 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
WO2004082796A2 (en) | 2003-03-14 | 2004-09-30 | The Trustees Of Columbia University In The City Ofnew York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
US8007823B2 (en) * | 2003-04-03 | 2011-08-30 | Corporation De L'ecole Polytechnique De Montreal | Microporous articles comprising biodegradable medical polymers, method of preparation thereof and method of use thereof |
US7618646B2 (en) * | 2003-06-06 | 2009-11-17 | Humanautocell Gmbh | Matrix, cell implant and method for their production and use |
EP1664168B1 (en) * | 2003-08-29 | 2008-12-03 | Mayo Foundation for Medical Education and Research | Hydrogel porogens for fabricating biodegradable scaffolds |
US7309232B2 (en) * | 2003-10-10 | 2007-12-18 | Dentigenix Inc. | Methods for treating dental conditions using tissue scaffolds |
US7846466B2 (en) * | 2004-06-10 | 2010-12-07 | Northwestern University | Biodegradable scaffolds and uses thereof |
US8512730B2 (en) * | 2004-07-12 | 2013-08-20 | Isto Technologies, Inc. | Methods of tissue repair and compositions therefor |
AU2005287402B2 (en) * | 2004-07-12 | 2011-03-03 | Isto Technologies Ii, Llc | Tissue matrix system |
JP2008513159A (ja) * | 2004-09-21 | 2008-05-01 | マサチューセッツ・インスティチュート・オブ・テクノロジー | 勾配骨組及びその作成方法 |
JP4738800B2 (ja) * | 2004-10-15 | 2011-08-03 | 株式会社ジーシー | ブロック状細胞工学用支持体の製造方法 |
AU2005304567B2 (en) * | 2004-11-12 | 2011-10-27 | Mayo Foundation For Medical Education And Research | Photocrosslinkable poly(caprolactone fumarate) |
DE102004059169A1 (de) | 2004-12-08 | 2006-06-22 | Humanautocell Gmbh | Verfahren zum Testen von Substanzen an Biomatrices |
US7700355B2 (en) * | 2005-01-07 | 2010-04-20 | Industrial Technology Research Institute | Methods of producing a porous matrix for culturing and recovering cells |
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AR057629A1 (es) | 2005-11-22 | 2007-12-05 | Aderans Res Inst Inc | Injerto de foliculos pilosos de piel obtenida por ingenieria de tejidos |
ES2528272T3 (es) * | 2005-12-07 | 2015-02-06 | Isto Technologies Inc. | Métodos de reparación de cartílago |
SI2347775T1 (sl) | 2005-12-13 | 2020-10-30 | President And Fellows Of Harvard College | Ogrodja za celično transplantacijo |
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US7727399B2 (en) | 2006-05-22 | 2010-06-01 | The Trustees Of Columbia University In The City Of New York | Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams |
EP2044192B1 (en) * | 2006-07-07 | 2017-04-12 | University of Miami | Enhanced oxygen cell culture platforms |
US9175254B2 (en) * | 2006-07-07 | 2015-11-03 | University Of Miami | Enhanced oxygen cell culture platforms |
JP4995587B2 (ja) * | 2007-01-29 | 2012-08-08 | 日東電工株式会社 | ポリε−カプロラクトン発泡体とその製造方法 |
US9770535B2 (en) * | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
US8277832B2 (en) * | 2007-10-10 | 2012-10-02 | The University Of Kansas | Microsphere-based materials with predefined 3D spatial and temporal control of biomaterials, porosity and/or bioactive signals |
MX2010008591A (es) | 2008-02-04 | 2010-08-30 | Univ Columbia | Dispositivos, sistemas y metodos de separacion de fluidos. |
CA2715460C (en) | 2008-02-13 | 2020-02-18 | President And Fellows Of Harvard College | Continuous cell programming devices |
US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
US9012399B2 (en) * | 2008-05-30 | 2015-04-21 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
CA2731374C (en) | 2008-07-30 | 2019-04-02 | Mesynthes Limited | Tissue scaffolds derived from forestomach extracellular matrix |
US20100203102A1 (en) * | 2009-02-10 | 2010-08-12 | Warsaw Orthopedic, Inc. | Compositions and methods for treating post-operative pain using bupivacaine and an anti-onflammatory agent |
WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
US20110015672A1 (en) * | 2009-07-17 | 2011-01-20 | Tyco Healthcare Group Lp | Method for Coating a Medical Device |
EP2461828B1 (en) | 2009-07-31 | 2017-06-21 | President and Fellows of Harvard College | Programming of cells for tolerogenic therapies |
US20120288537A1 (en) * | 2010-01-13 | 2012-11-15 | The Regents Of The University Of Michigan | Active self-healing biomaterial system |
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ES2773858T3 (es) | 2010-10-06 | 2020-07-15 | Harvard College | Hidrogeles formadores de poros inyectables para terapias celulares basadas en materiales |
US9603894B2 (en) | 2010-11-08 | 2017-03-28 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
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US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
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US9486512B2 (en) | 2011-06-03 | 2016-11-08 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
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CN102258807B (zh) * | 2011-07-15 | 2013-07-24 | 山东大学 | 一种组织工程用猪脱细胞真皮基质的调孔方法 |
ES2773895T3 (es) | 2012-04-16 | 2020-07-15 | Harvard College | Composiciones de sílice mesoporosa para modular las respuestas inmunitarias |
CA2876495C (en) | 2012-06-21 | 2023-10-17 | Northwestern University | Peptide conjugated particles |
US9388312B2 (en) | 2012-07-26 | 2016-07-12 | Invista North America S.A.R.L. | Thermoplastic composition for use in high impact applications |
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US20140120152A1 (en) * | 2012-10-31 | 2014-05-01 | Northwestern University | Scaffold Delivery of Immune Suppressors and Transplant Material for Control of Transplant Rejection |
US9707323B2 (en) * | 2012-11-12 | 2017-07-18 | Warsaw Orthopedic, Inc. | Devices and methods for inhibiting adhesion formation |
US10245306B2 (en) | 2012-11-16 | 2019-04-02 | Isto Technologies Ii, Llc | Flexible tissue matrix and methods for joint repair |
ITTO20130284A1 (it) * | 2013-04-09 | 2014-10-10 | Fond Istituto Italiano Di Tecnologia | Procedimento per la produzione di microparticelle polimeriche sagomate |
FI3033102T4 (fi) | 2013-08-13 | 2024-03-01 | Univ Northwestern | Peptidikonjugoituja hiukkasia |
US10682400B2 (en) | 2014-04-30 | 2020-06-16 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
US10179191B2 (en) | 2014-10-09 | 2019-01-15 | Isto Technologies Ii, Llc | Flexible tissue matrix and methods for joint repair |
US11786457B2 (en) | 2015-01-30 | 2023-10-17 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
JP7094533B2 (ja) * | 2015-04-10 | 2022-07-04 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫細胞捕捉デバイスおよびその製造および使用方法 |
EP3393514A4 (en) | 2015-12-23 | 2019-08-14 | Cour Pharmaceuticals Development Company Inc. | PARTICLES CONJUGATED BY COVALENCE OF THE POLYMER-ANTIGEN TYPE |
CN115487351A (zh) | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
JP2019522486A (ja) | 2016-07-13 | 2019-08-15 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 抗原提示細胞模倣足場およびそれを作製および使用するための方法 |
EP3717552A4 (en) * | 2017-11-28 | 2022-03-23 | Northwestern University | COMPOSITIONS CONTAINING WATER-SOLUBLE SALT PARTICLES AND POROUS MATERIALS MADE THEREOF |
RS64603B1 (sr) * | 2018-02-27 | 2023-10-31 | Univ Minnesota | Polilaktidne pene |
US20210017348A1 (en) * | 2018-04-02 | 2021-01-21 | Optipharm Co., Ltd | Alginate microcapsules for cell encapsulation and, manufacturing method therefor |
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US4461876A (en) * | 1982-09-09 | 1984-07-24 | Columbia University | Polymeric reagents for the isolation and protection of carbonyl compounds |
US4636526A (en) * | 1985-02-19 | 1987-01-13 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
US5567612A (en) | 1986-11-20 | 1996-10-22 | Massachusetts Institute Of Technology | Genitourinary cell-matrix structure for implantation into a human and a method of making |
US5041138A (en) | 1986-11-20 | 1991-08-20 | Massachusetts Institute Of Technology | Neomorphogenesis of cartilage in vivo from cell culture |
US5512600A (en) | 1993-01-15 | 1996-04-30 | Massachusetts Institute Of Technology | Preparation of bonded fiber structures for cell implantation |
US5709854A (en) | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
DE4325879C3 (de) * | 1993-08-02 | 1999-05-20 | Depron Bv | Folie aus einem thermoplastischen Kunststoffschaum, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
WO1995005083A1 (en) * | 1993-08-13 | 1995-02-23 | Smith & Nephew Richards Inc | Microporous polymeric foams and microtextured surfaces |
JP4085341B2 (ja) * | 1997-03-31 | 2008-05-14 | ザ、リージエンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン | 開いたポアの生分解性マトリックス |
-
1998
- 1998-03-31 JP JP54188498A patent/JP4085341B2/ja not_active Expired - Fee Related
- 1998-03-31 US US09/402,119 patent/US6281256B1/en not_active Expired - Lifetime
- 1998-03-31 AT AT98913264T patent/ATE249491T1/de not_active IP Right Cessation
- 1998-03-31 WO PCT/US1998/006188 patent/WO1998044027A1/en active IP Right Grant
- 1998-03-31 CA CA002285329A patent/CA2285329A1/en not_active Abandoned
- 1998-03-31 DK DK98913264T patent/DK0991705T3/da active
- 1998-03-31 EP EP98913264A patent/EP0991705B1/en not_active Expired - Lifetime
- 1998-03-31 DE DE69818052T patent/DE69818052T2/de not_active Expired - Lifetime
- 1998-03-31 AU AU67860/98A patent/AU736102B2/en not_active Ceased
- 1998-03-31 ES ES98913264T patent/ES2205467T3/es not_active Expired - Lifetime
-
2001
- 2001-08-28 US US09/939,714 patent/US6797738B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69818052D1 (de) | 2003-10-16 |
ATE249491T1 (de) | 2003-09-15 |
AU6786098A (en) | 1998-10-22 |
EP0991705B1 (en) | 2003-09-10 |
JP2002514253A (ja) | 2002-05-14 |
US6281256B1 (en) | 2001-08-28 |
US6797738B2 (en) | 2004-09-28 |
DE69818052T2 (de) | 2004-07-08 |
WO1998044027A1 (en) | 1998-10-08 |
CA2285329A1 (en) | 1998-10-08 |
ES2205467T3 (es) | 2004-05-01 |
AU736102B2 (en) | 2001-07-26 |
US20020045672A1 (en) | 2002-04-18 |
JP4085341B2 (ja) | 2008-05-14 |
EP0991705A1 (en) | 2000-04-12 |
EP0991705A4 (en) | 2001-12-12 |
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