DK0984961T3 - Azaindener - Google Patents

Azaindener

Info

Publication number: DK0984961T3
Authority: DK; Denmark
Prior art keywords: azaindener
Prior art date: 1997-04-01

Application number

DK98914202T

Other languages

Danish (da)

English (en)

Inventor

David Cheshire

David Cladingboel

Martin Cooper

David Hardern

Simon Hirst

Carol Manners

Michael Stocks

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-01

Filing date

1998-03-27

Publication date

2001-09-17

1997-04-01 Priority claimed from SE9701194A external-priority patent/SE9701194D0/xx

1997-06-09 Priority claimed from SE9702200A external-priority patent/SE9702200D0/xx

1997-11-28 Priority claimed from SE9704402A external-priority patent/SE9704402D0/xx

1998-03-27 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2001-09-17 Application granted granted Critical

2001-09-17 Publication of DK0984961T3 publication Critical patent/DK0984961T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

DK98914202T 1997-04-01 1998-03-27 Azaindener DK0984961T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE9701194A SE9701194D0 (sv)	1997-04-01	1997-04-01	Novel compounds
SE9702200A SE9702200D0 (sv)	1997-06-09	1997-06-09	Novel compounds
SE9704402A SE9704402D0 (sv)	1997-11-28	1997-11-28	Novel compounds
PCT/SE1998/000575 WO1998043971A1 (en)	1997-04-01	1998-03-27	Novel pyridine derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
DK0984961T3 true DK0984961T3 (da)	2001-09-17

Family

ID=27355867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98914202T DK0984961T3 (da)	1997-04-01	1998-03-27	Azaindener

Country Status (23)

Country	Link
US (1)	US6143751A (zh)
EP (1)	EP0984961B1 (zh)
JP (1)	JP2001517228A (zh)
KR (1)	KR20010005840A (zh)
CN (1)	CN1258296A (zh)
AR (1)	AR012216A1 (zh)
AT (1)	ATE202351T1 (zh)
AU (1)	AU6861198A (zh)
BR (1)	BR9808447A (zh)
CA (1)	CA2284597A1 (zh)
DE (1)	DE69800970T2 (zh)
DK (1)	DK0984961T3 (zh)
EE (1)	EE9900435A (zh)
ES (1)	ES2159943T3 (zh)
GR (1)	GR3036638T3 (zh)
ID (1)	ID23163A (zh)
IL (1)	IL131854A0 (zh)
NO (1)	NO994764L (zh)
PL (1)	PL335884A1 (zh)
PT (1)	PT984961E (zh)
SK (1)	SK133399A3 (zh)
TR (1)	TR199902433T2 (zh)
WO (1)	WO1998043971A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2407400A (en) *	1999-01-08	2000-07-24	Vertex Pharmaceuticals Incorporated	Process for the formation of intermediates useful for the preparation of pharmaceuticals
CA2314458A1 (en) *	1999-08-02	2001-02-02	Kazumi Okuro	Process for production of 3-(3-pyridyl)-1-propanol derivatives
US6376524B1 (en)	2000-06-21	2002-04-23	Sunesis Pharmaceuticals, Inc.	Triphenyl compounds as interleukin-4 antagonists
JO3598B1 (ar) *	2006-10-10	2020-07-05	Infinity Discovery Inc	الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
CN102834401B (zh) *	2010-02-03	2016-08-24	无限药品股份有限公司	脂肪酸酰胺水解酶抑制剂
WO2013097052A1 (en)	2011-12-30	2013-07-04	Abbott Laboratories	Bromodomain inhibitors
CN104718201A (zh)	2012-06-12	2015-06-17	艾伯维公司	吡啶酮和哒嗪酮衍生物
PL3442972T3 (pl)	2016-04-15	2020-07-27	Abbvie Inc.	Inhibitory bromodomeny

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA877650B (en) *	1986-10-14	1988-12-28	Searle & Co	Alpha-(phenylalkyl)pyridinealkanol derivatives
EP0264114A1 (en) *	1986-10-16	1988-04-20	G.D. Searle & Co.	Alpha-[(phenylmethoxy)methyl]pyridine-alkanol derivatives
TR199801000T2 (xx) *	1995-12-06	1998-08-21	Astra Pharmaceuticals Ltd.	Bile�ikler

1998
- 1998-03-27 WO PCT/SE1998/000575 patent/WO1998043971A1/en not_active Application Discontinuation
- 1998-03-27 JP JP54155998A patent/JP2001517228A/ja active Pending
- 1998-03-27 IL IL13185498A patent/IL131854A0/xx unknown
- 1998-03-27 SK SK1333-99A patent/SK133399A3/sk unknown
- 1998-03-27 PT PT98914202T patent/PT984961E/pt unknown
- 1998-03-27 DE DE69800970T patent/DE69800970T2/de not_active Expired - Fee Related
- 1998-03-27 ID IDW991125D patent/ID23163A/id unknown
- 1998-03-27 PL PL98335884A patent/PL335884A1/xx unknown
- 1998-03-27 AU AU68611/98A patent/AU6861198A/en not_active Abandoned
- 1998-03-27 TR TR1999/02433T patent/TR199902433T2/xx unknown
- 1998-03-27 CA CA002284597A patent/CA2284597A1/en not_active Abandoned
- 1998-03-27 AT AT98914202T patent/ATE202351T1/de not_active IP Right Cessation
- 1998-03-27 ES ES98914202T patent/ES2159943T3/es not_active Expired - Lifetime
- 1998-03-27 DK DK98914202T patent/DK0984961T3/da active
- 1998-03-27 EP EP98914202A patent/EP0984961B1/en not_active Expired - Lifetime
- 1998-03-27 BR BR9808447-0A patent/BR9808447A/pt not_active IP Right Cessation
- 1998-03-27 KR KR1019997008914A patent/KR20010005840A/ko not_active Application Discontinuation
- 1998-03-27 CN CN98805505A patent/CN1258296A/zh active Pending
- 1998-03-27 US US09/068,521 patent/US6143751A/en not_active Expired - Fee Related
- 1998-03-27 EE EEP199900435A patent/EE9900435A/xx unknown
- 1998-03-31 AR ARP980101459A patent/AR012216A1/es unknown
1999
- 1999-09-30 NO NO994764A patent/NO994764L/no not_active Application Discontinuation
2001
- 2001-09-18 GR GR20010401496T patent/GR3036638T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL131854A0 (en)	2001-03-19
SK133399A3 (en)	2000-05-16
PT984961E (pt)	2001-11-30
JP2001517228A (ja)	2001-10-02
PL335884A1 (en)	2000-05-22
CA2284597A1 (en)	1998-10-08
NO994764D0 (no)	1999-09-30
DE69800970D1 (de)	2001-07-26
ID23163A (id)	2000-03-23
EP0984961A1 (en)	2000-03-15
KR20010005840A (ko)	2001-01-15
BR9808447A (pt)	2000-05-23
TR199902433T2 (xx)	2000-04-21
AU6861198A (en)	1998-10-22
CN1258296A (zh)	2000-06-28
ATE202351T1 (de)	2001-07-15
AR012216A1 (es)	2000-09-27
DE69800970T2 (de)	2002-04-04
GR3036638T3 (en)	2001-12-31
WO1998043971A1 (en)	1998-10-08
EP0984961B1 (en)	2001-06-20
EE9900435A (et)	2000-04-17
US6143751A (en)	2000-11-07
NO994764L (no)	1999-09-30
ES2159943T3 (es)	2001-10-16

Publication	Publication Date	Title
DE19810476B4 (de)	2005-10-20	Laryngomaske
DE29719526U1 (de)	1998-02-12	Neurotrokar
ATA93198A (de)	2001-01-15	Fluoxetinpellets
DE29709558U1 (de)	1997-09-18	Barhocker
DE59710388D1 (de)	2003-08-07	Mikropolarimeter
DE59801498D1 (de)	2001-10-25	Dioxacycloalkan-8-one
DK0984961T3 (da)	2001-09-17	Azaindener
ATA111897A (de)	1999-06-15	Kimme
ATE236897T1 (de)	2003-04-15	3-benzylpiperidine
ATA112597A (de)	1999-03-15	Snowboard - bindung
DE29707066U1 (de)	1997-08-14	Mikroretroflektor
DE29706358U1 (de)	1997-06-05	Körperschützer
DE29701531U1 (de)	1997-05-07	Säschar
DE29714623U1 (de)	1997-10-30	Kantenband
ATA86797A (de)	2002-02-15	Verschleissschuh
DE59800820D1 (de)	2001-07-12	Stiellose kniegelenkendoprothese
BR9701194A (pt)	1998-12-15	Hidrociclo
DE29713914U1 (de)	1998-03-26	Rechaud
DE29722383U1 (de)	1998-04-09	Sauenkirre
DE29722566U1 (de)	1998-04-02	Isolierplanstein
ATA46498A (de)	2002-02-15	Kunststoffgleitbahn
ATE421585T1 (de)	2009-02-15	Motlinhomologe
BR7700737U (pt)	1998-12-15	Tarraxa
BR7702133U (pt)	1999-06-29	Telecaju
BR9704162A (pt)	1999-04-27	Anti-queimaduras