DK0888316T3 - 2-(3H)-oxazolonderivater og deres anvendelse som cox-2 inhibitorer - Google Patents

2-(3H)-oxazolonderivater og deres anvendelse som cox-2 inhibitorer

Info

Publication number
DK0888316T3
DK0888316T3 DK97915396T DK97915396T DK0888316T3 DK 0888316 T3 DK0888316 T3 DK 0888316T3 DK 97915396 T DK97915396 T DK 97915396T DK 97915396 T DK97915396 T DK 97915396T DK 0888316 T3 DK0888316 T3 DK 0888316T3
Authority
DK
Denmark
Prior art keywords
cox
inhibitors
oxazolone derivatives
oxazolone
derivatives
Prior art date
Application number
DK97915396T
Other languages
Danish (da)
English (en)
Inventor
Duran Carles Puig
Noguera Ferran Pujol
Forner Dolors Fernandez
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8294266&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0888316(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of DK0888316T3 publication Critical patent/DK0888316T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK97915396T 1996-03-21 1997-03-19 2-(3H)-oxazolonderivater og deres anvendelse som cox-2 inhibitorer DK0888316T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009600685A ES2125161B1 (es) 1996-03-21 1996-03-21 Nuevos derivados de 2-(3h)-oxazolona.
PCT/EP1997/001386 WO1997034882A1 (en) 1996-03-21 1997-03-19 2-(3h)-oxazolone derivatives and their use as cox-2 inhibitors

Publications (1)

Publication Number Publication Date
DK0888316T3 true DK0888316T3 (da) 2000-11-27

Family

ID=8294266

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97915396T DK0888316T3 (da) 1996-03-21 1997-03-19 2-(3H)-oxazolonderivater og deres anvendelse som cox-2 inhibitorer

Country Status (30)

Country Link
US (1) US6869968B1 (es)
EP (1) EP0888316B1 (es)
JP (1) JP3810091B2 (es)
KR (1) KR100496395B1 (es)
CN (1) CN1110488C (es)
AR (1) AR006340A1 (es)
AT (1) ATE197294T1 (es)
AU (1) AU713811B2 (es)
BR (1) BR9708141A (es)
CA (1) CA2249420A1 (es)
CO (1) CO4780046A1 (es)
CZ (1) CZ294963B6 (es)
DE (1) DE69703437T2 (es)
DK (1) DK0888316T3 (es)
ES (2) ES2125161B1 (es)
GR (1) GR3035096T3 (es)
HK (1) HK1015371A1 (es)
ID (1) ID16778A (es)
IL (1) IL126206A (es)
NO (1) NO311761B1 (es)
NZ (1) NZ331901A (es)
PE (1) PE42898A1 (es)
PL (1) PL188722B1 (es)
PT (1) PT888316E (es)
RU (1) RU2194043C2 (es)
TW (1) TW426674B (es)
UA (1) UA52645C2 (es)
UY (1) UY24499A1 (es)
WO (1) WO1997034882A1 (es)
ZA (1) ZA972203B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125161B1 (es) 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
FR2753449B1 (fr) * 1996-09-13 1998-12-04 Union Pharma Scient Appl Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
ES2131015B1 (es) * 1997-09-12 2000-03-01 Almirall Prodesfarma Sa Nuevos derivados de 2-(3h)-oxazolona, procedimientos para su preparacion y su empleo en composiciones farmaceuticas.
ES2154561B1 (es) * 1998-09-25 2001-12-01 Almirall Prodesfarma Sa Derivados de 2-fenilpiran-4-ona.
ES2168895A1 (es) * 1999-03-26 2002-06-16 Almirall Prodesfarma Sa Derivados de 2-fenilpiran-4-ona.
EP1246621A4 (en) 1999-12-23 2004-11-24 Nitromed Inc NITROSED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS FOR THEIR USE
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
JP2005535642A (ja) 2002-06-28 2005-11-24 ニトロメッド インコーポレーティッド オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
ES2215474B1 (es) 2002-12-24 2005-12-16 J. URIACH & CIA S.A. Nuevos derivados de fosforamida.
ES2213485B1 (es) 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
ATE342722T1 (de) 2003-05-07 2006-11-15 Osteologix As Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
CN1309717C (zh) * 2003-06-03 2007-04-11 李小虎 4－芳基－5h－噻吩－2－酮衍生物、其制法和用途
CA2676413A1 (en) * 2007-01-19 2008-07-31 Mallinckrodt Inc. Diagnostic and therapeutic cyclooxygenase-2 binding ligands
WO2022195579A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866182A (en) 1988-02-18 1989-09-12 Merrell Dow Pharmaceuticals Inc. Cardiotonic alkanoyl and aroyl oxazolones
US5380738A (en) 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
DE4435547A1 (de) 1994-10-05 1996-04-11 Bayer Ag Sulfonylaminocarbonyltriazolinone mit über Sauerstoff und Schwefel gebundenen Substituenten
JP2636819B2 (ja) 1994-12-20 1997-07-30 日本たばこ産業株式会社 オキサゾール系複素環式芳香族化合物
ES2125161B1 (es) 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
FR2753449B1 (fr) * 1996-09-13 1998-12-04 Union Pharma Scient Appl Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique

Also Published As

Publication number Publication date
TW426674B (en) 2001-03-21
RU2194043C2 (ru) 2002-12-10
NO984325L (no) 1998-11-23
HK1015371A1 (en) 1999-10-15
CO4780046A1 (es) 1999-05-26
EP0888316B1 (en) 2000-11-02
DE69703437D1 (de) 2000-12-07
CZ294963B6 (cs) 2005-04-13
MX9701944A (es) 1998-06-30
PL328915A1 (en) 1999-03-01
US6869968B1 (en) 2005-03-22
DE69703437T2 (de) 2001-03-08
NZ331901A (en) 1999-10-28
UA52645C2 (uk) 2003-01-15
GR3035096T3 (en) 2001-03-30
JP3810091B2 (ja) 2006-08-16
PL188722B1 (pl) 2005-04-29
AR006340A1 (es) 1999-08-25
EP0888316A1 (en) 1999-01-07
ES2125161A1 (es) 1999-02-16
CZ297998A3 (cs) 1999-02-17
IL126206A (en) 2001-06-14
ZA972203B (en) 1997-09-25
UY24499A1 (es) 1997-04-02
NO984325D0 (no) 1998-09-17
CN1218459A (zh) 1999-06-02
ES2125161B1 (es) 1999-11-16
BR9708141A (pt) 1999-07-27
AU2289397A (en) 1997-10-10
ES2151254T3 (es) 2000-12-16
NO311761B1 (no) 2002-01-21
ATE197294T1 (de) 2000-11-15
KR100496395B1 (ko) 2005-09-27
IL126206A0 (en) 1999-05-09
ID16778A (id) 1997-11-13
PT888316E (pt) 2001-02-28
JP2000506876A (ja) 2000-06-06
CA2249420A1 (en) 1997-09-25
CN1110488C (zh) 2003-06-04
WO1997034882A1 (en) 1997-09-25
AU713811B2 (en) 1999-12-09
KR20000064727A (ko) 2000-11-06
PE42898A1 (es) 1998-08-12

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