DK0880502T3 - Aminoheterocykliske derivater som antithrombotiske eller antikoagulerende midler - Google Patents
Aminoheterocykliske derivater som antithrombotiske eller antikoagulerende midlerInfo
- Publication number
- DK0880502T3 DK0880502T3 DK97902438T DK97902438T DK0880502T3 DK 0880502 T3 DK0880502 T3 DK 0880502T3 DK 97902438 T DK97902438 T DK 97902438T DK 97902438 T DK97902438 T DK 97902438T DK 0880502 T3 DK0880502 T3 DK 0880502T3
- Authority
- DK
- Denmark
- Prior art keywords
- sup
- antithrombotic
- anticoagulants
- variety
- heterocyclic derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9602166.2A GB9602166D0 (en) | 1996-02-02 | 1996-02-02 | Aminoheterocyclic derivatives |
| EP97902438A EP0880502B1 (en) | 1996-02-02 | 1997-01-31 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0880502T3 true DK0880502T3 (da) | 2004-11-29 |
Family
ID=10788043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97902438T DK0880502T3 (da) | 1996-02-02 | 1997-01-31 | Aminoheterocykliske derivater som antithrombotiske eller antikoagulerende midler |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7173025B1 (da) |
| EP (1) | EP0880502B1 (da) |
| JP (1) | JP2000504337A (da) |
| AT (1) | ATE275131T1 (da) |
| AU (1) | AU1608597A (da) |
| DE (1) | DE69730490T2 (da) |
| DK (1) | DK0880502T3 (da) |
| ES (1) | ES2225948T3 (da) |
| GB (2) | GB9602166D0 (da) |
| PT (1) | PT880502E (da) |
| SI (1) | SI0880502T1 (da) |
| WO (1) | WO1997028129A1 (da) |
| ZA (1) | ZA97697B (da) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| US6313127B1 (en) | 1996-02-02 | 2001-11-06 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
| GB9602166D0 (en) | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
| PL331599A1 (en) * | 1996-08-14 | 1999-08-02 | Zeneca Ltd | Substituted derivatives of pyrimidine and their pharmaceutical application |
| UA56197C2 (uk) * | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
| ATE242774T1 (de) | 1997-02-13 | 2003-06-15 | Astrazeneca Ab | Heterozyklische verbindungen die als oxido- squalen-zyklase-inhibitoren anwendung finden |
| JP2001511798A (ja) | 1997-02-13 | 2001-08-14 | ゼネカ・リミテッド | オキシド−スクアレンシクラーゼ抑制剤として有用な複素環化合物 |
| GB9715894D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic derivatives |
| HUP0101810A3 (en) | 1998-01-27 | 2002-05-28 | Aventis Pharm Prod Inc | Substituted oxoazaheterocyclyl factor xa inhibitors and pharmaceutical compositions containing them |
| GB9809349D0 (en) | 1998-05-02 | 1998-07-01 | Zeneca Ltd | Heterocyclic derivatives |
| TR200003200T2 (tr) | 1998-05-02 | 2001-02-21 | Astrazeneca Ab | Faktör XA'yı önleyen heterosiklik türevler. |
| US6586475B1 (en) | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
| GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
| EP1302462A4 (en) * | 2000-07-17 | 2007-07-18 | Takeda Pharmaceutical | Sulphonic derivatives, process for their preparation and their use |
| KR20040015036A (ko) * | 2000-12-06 | 2004-02-18 | 아벤티스 파마 도이칠란트 게엠베하 | 인자 Ｘａ 억제제로서의 구아니딘 및 아미딘 유도체 |
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| US7227035B2 (en) | 2002-11-18 | 2007-06-05 | Chemocentryx | Bis-aryl sulfonamides |
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| DK1569912T3 (da) | 2002-12-03 | 2015-06-29 | Pharmacyclics Inc | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazol-5-carboxamidin derivater som factor VIIa inhibitorer. |
| PL1608374T3 (pl) | 2003-03-24 | 2009-08-31 | Axikin Pharmaceuticals Inc | 2-Fenoksy i 2-fenylosulfonoamidowe pochodne o aktywności antagonistycznej w stosunku do CCR3 do leczenia astmy i innych zaburzeń o podłożu zapalnym lub immunologicznym |
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| CN110437113B (zh) * | 2019-07-29 | 2021-02-09 | 苏州华道生物药业股份有限公司 | 一种4-苯磺酰苯甲酸的合成方法 |
| CN116410143A (zh) * | 2021-12-29 | 2023-07-11 | 杭州奥默医药股份有限公司 | 一种多取代脲嘧啶衍生物及其制备方法和应用 |
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-
1996
- 1996-02-02 GB GBGB9602166.2A patent/GB9602166D0/en active Pending
-
1997
- 1997-01-22 GB GBGB9701284.3A patent/GB9701284D0/en active Pending
- 1997-01-28 ZA ZA9700697A patent/ZA97697B/xx unknown
- 1997-01-31 ES ES97902438T patent/ES2225948T3/es not_active Expired - Lifetime
- 1997-01-31 JP JP9527428A patent/JP2000504337A/ja not_active Ceased
- 1997-01-31 PT PT97902438T patent/PT880502E/pt unknown
- 1997-01-31 DK DK97902438T patent/DK0880502T3/da active
- 1997-01-31 AU AU16085/97A patent/AU1608597A/en not_active Abandoned
- 1997-01-31 WO PCT/GB1997/000284 patent/WO1997028129A1/en active IP Right Grant
- 1997-01-31 DE DE69730490T patent/DE69730490T2/de not_active Expired - Fee Related
- 1997-01-31 AT AT97902438T patent/ATE275131T1/de not_active IP Right Cessation
- 1997-01-31 US US09/117,436 patent/US7173025B1/en not_active Expired - Fee Related
- 1997-01-31 SI SI9730674T patent/SI0880502T1/xx unknown
- 1997-01-31 EP EP97902438A patent/EP0880502B1/en not_active Expired - Lifetime
-
2003
- 2003-05-02 US US10/427,991 patent/US20030207882A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GB9701284D0 (en) | 1997-03-12 |
| GB9602166D0 (en) | 1996-04-03 |
| ATE275131T1 (de) | 2004-09-15 |
| SI0880502T1 (en) | 2005-02-28 |
| WO1997028129A1 (en) | 1997-08-07 |
| PT880502E (pt) | 2004-12-31 |
| EP0880502B1 (en) | 2004-09-01 |
| ES2225948T3 (es) | 2005-03-16 |
| DE69730490T2 (de) | 2005-09-29 |
| ZA97697B (en) | 1997-08-04 |
| JP2000504337A (ja) | 2000-04-11 |
| EP0880502A1 (en) | 1998-12-02 |
| US7173025B1 (en) | 2007-02-06 |
| AU1608597A (en) | 1997-08-22 |
| DE69730490D1 (de) | 2004-10-07 |
| US20030207882A1 (en) | 2003-11-06 |
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