DK0804439T3 - Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelser - Google Patents
Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelserInfo
- Publication number
- DK0804439T3 DK0804439T3 DK95944791T DK95944791T DK0804439T3 DK 0804439 T3 DK0804439 T3 DK 0804439T3 DK 95944791 T DK95944791 T DK 95944791T DK 95944791 T DK95944791 T DK 95944791T DK 0804439 T3 DK0804439 T3 DK 0804439T3
- Authority
- DK
- Denmark
- Prior art keywords
- beta
- dihydroxy
- unsubstituted
- mesosubstituted
- isobacteriochlorines
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Radiology & Medical Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/329,577 US5648485A (en) | 1994-10-26 | 1994-10-26 | β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
PCT/CA1995/000602 WO1996013504A1 (en) | 1994-10-26 | 1995-10-25 | β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0804439T3 true DK0804439T3 (da) | 2004-02-02 |
Family
ID=23286058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95944791T DK0804439T3 (da) | 1994-10-26 | 1995-10-25 | Beta, beta'-dihydroxy-mesosubstituerede chloriner, -isobacteriochloriner, -bacteriochloriner og fremgangsmåder til fremstilling af samme ud fra beta, beta'-usubstituerede tetrapyrroliske, makrocykliske forbindelser |
Country Status (20)
Country | Link |
---|---|
US (2) | US5648485A (ja) |
EP (1) | EP0804439B1 (ja) |
JP (2) | JP3228296B2 (ja) |
KR (1) | KR970707129A (ja) |
CN (1) | CN1043143C (ja) |
AT (1) | ATE250064T1 (ja) |
AU (1) | AU704971B2 (ja) |
CA (1) | CA2199399C (ja) |
CZ (1) | CZ294496B6 (ja) |
DE (1) | DE69531795T2 (ja) |
DK (1) | DK0804439T3 (ja) |
ES (1) | ES2208701T3 (ja) |
FI (1) | FI971734A (ja) |
HU (1) | HU221102B1 (ja) |
NO (1) | NO308411B1 (ja) |
NZ (1) | NZ294203A (ja) |
PL (1) | PL182239B1 (ja) |
PT (1) | PT804439E (ja) |
TW (1) | TW301648B (ja) |
WO (1) | WO1996013504A1 (ja) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648485A (en) * | 1994-10-26 | 1997-07-15 | University Of British Columbia | β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
GB9610967D0 (en) | 1996-05-24 | 1996-07-31 | Cambridge Antibody Tech | Specific binding members,materials and methods |
WO1998031219A1 (en) * | 1997-01-21 | 1998-07-23 | The American National Red Cross | Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light |
WO2000000204A1 (en) | 1997-02-14 | 2000-01-06 | Miravant Pharmaceuticals, Inc. | Indium photosensitizers for pdt |
FR2760841B1 (fr) * | 1997-03-12 | 1999-04-16 | Commissariat Energie Atomique | Determination par resonance magnetique nucleaire de la configuration absolue d'amino-acides ou de leur derives et complexes metalliques de porphyrines chirales utilisables pour cette determination |
DE19814405C2 (de) * | 1998-03-31 | 2000-03-02 | Schastak Astrid | Porphyrine und ihre Verwendung als Photosensitizer |
US20030176663A1 (en) * | 1998-05-11 | 2003-09-18 | Eidgenossische Technische Hochscule | Specific binding molecules for scintigraphy |
ES2260941T3 (es) | 1998-10-20 | 2006-11-01 | THE PROCTER & GAMBLE COMPANY | Detergentes para la ropa que comprenden alquilbenceno sulfonatos modificados. |
US6514926B1 (en) | 1998-10-20 | 2003-02-04 | The Procter & Gamble Company | Laundry detergents comprising modified alkylbenzene sulfonates |
US7022843B1 (en) | 1999-04-14 | 2006-04-04 | The University Of British Columbia | β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
AU4278400A (en) | 1999-04-14 | 2000-11-14 | University Of British Columbia, The | Improved beta,beta,-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
US20020022032A1 (en) * | 1999-04-23 | 2002-02-21 | Curry Patrick Mark | Immuno-adjuvant PDT treatment of metastatic tumors |
US6376483B1 (en) | 1999-05-27 | 2002-04-23 | Miravant Pharmaceuticals, Inc. | Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production |
US7897140B2 (en) * | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
EP1259548A1 (en) | 2000-02-24 | 2002-11-27 | Eidgenössische Technische Hochschule Zürich | Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis |
WO2001085213A2 (en) | 2000-05-08 | 2001-11-15 | The University Of British Columbia | Supports for photosensitizer formulations |
US6693093B2 (en) * | 2000-05-08 | 2004-02-17 | The University Of British Columbia (Ubc) | Drug delivery systems for photodynamic therapy |
US6559374B2 (en) * | 2000-07-21 | 2003-05-06 | North Carolina State University | Trans beta substituted chlorins and methods of making and using the same |
CN1246333C (zh) * | 2000-09-07 | 2006-03-22 | 舍林股份公司 | EDb-纤粘连蛋白结构域(II)的受体 |
US6958389B2 (en) | 2000-09-08 | 2005-10-25 | San-Ei Gen F.F.I. Inc. | Tetraphenylbacteriochlorin derivatives and compositions containing the same |
WO2003039596A1 (en) * | 2001-11-09 | 2003-05-15 | Qlt Inc. | Photodynamic therapy for the treatment of hair loss |
WO2004002476A2 (en) | 2002-06-27 | 2004-01-08 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
WO2004005289A2 (en) * | 2002-07-02 | 2004-01-15 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
WO2004063200A1 (en) * | 2003-01-16 | 2004-07-29 | Techno Mart Co., Ltd | Porphyrin derivatives |
US7057100B2 (en) * | 2003-06-26 | 2006-06-06 | The J.C. Robinson Seed Co. | Inbred corn line W23129 |
GB0323358D0 (en) * | 2003-10-06 | 2003-11-05 | Green Grass Design Ltd | Novel compounds and processes |
JP4635493B2 (ja) * | 2003-10-09 | 2011-02-23 | 日本製紙株式会社 | ダル調塗工紙 |
GB2408265A (en) * | 2003-11-21 | 2005-05-25 | Univ Sheffield | Water-soluble hyperbranched polymer porphyrins |
US6995260B2 (en) * | 2004-05-20 | 2006-02-07 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
EP1848778B1 (en) | 2005-02-18 | 2013-04-10 | North Carolina State University | De novo synthesis of bacteriochlorins |
WO2007064841A2 (en) * | 2005-11-30 | 2007-06-07 | North Carolina State University | Porphyrinic compounds for use in flow cytometry |
WO2009038659A2 (en) * | 2007-09-14 | 2009-03-26 | Health Research, Inc. | Organically modified silica nanoparticles with covalently incorporated photosensitizers for drug delivery in photodynamic therapy |
US8253725B2 (en) * | 2007-12-28 | 2012-08-28 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method and system for generating surface models of geometric structures |
US20110070153A1 (en) * | 2008-08-13 | 2011-03-24 | Searete, Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
US9315510B2 (en) * | 2008-09-18 | 2016-04-19 | Biolitec Pharma Marketing Ltd | Method and application of unsymmetrically meso-substituted porphyrins and chlorins for PDT |
GB0819594D0 (en) | 2008-10-24 | 2008-12-03 | Univ Coimbrra | Process |
EP2379109B1 (en) | 2008-12-16 | 2020-10-07 | Bausch Health Companies Inc. | Combination of photodynamic therapy and anti-vegf agents in the treatment of unwanted choroidal neovasculature |
US9211283B2 (en) | 2009-12-11 | 2015-12-15 | Biolitec Pharma Marketing Ltd | Nanoparticle carrier systems based on human serum albumin for photodynamic therapy |
ES2638871T3 (es) | 2010-02-04 | 2017-10-24 | Morphotek, Inc. | Polipéptidos clorotoxina y conjugados y usos de los mismos |
JP2013532664A (ja) * | 2010-07-22 | 2013-08-19 | セラムオプテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | PDTのためのβ−官能化ジヒドロキシ−クロリンの用途 |
WO2013003507A1 (en) | 2011-06-27 | 2013-01-03 | Morphotek, Inc. | Multifunctional agents |
AU2012328679C1 (en) | 2011-10-25 | 2018-10-25 | Memorial Sloan-Kettering Cancer Center | Free PSA antibodies as diagnostics, prognostics and therapeutics for prostate cancer |
US9365542B2 (en) | 2012-10-26 | 2016-06-14 | Memorial Sloan-Kettering Cancer Center | Modulators of resistant androgen receptor |
US10766915B2 (en) | 2013-03-15 | 2020-09-08 | Sherri Ann McFARLAND | Metal-based coordination complexes as photodynamic compounds and their use |
CA2934524C (en) | 2013-12-23 | 2022-02-15 | Memorial Sloan-Kettering Cancer Center | Methods and compositions for treating cancer using peptide nucleic acid-based agents |
TWI474536B (zh) | 2014-07-01 | 2015-02-21 | Nat Univ Chung Hsing | 紫質光敏染料化合物以及染料敏化太陽能電池 |
EP3201201B1 (en) | 2014-09-30 | 2022-01-26 | biolitec unternehmensbeteiligungs II AG | Specifically meso-substituted porphyrins and chlorins for photodynamic therapy |
RU2615770C1 (ru) * | 2015-12-21 | 2017-04-11 | Общество с ограниченной ответственностью "Пермская химическая компания" | Борированные производные фторированных бактериохлоринов и их металлокомплексов, обладающие противоопухолевой активностью |
AU2017371379B2 (en) * | 2016-12-05 | 2021-08-26 | Salt And Light Pharmaceuticals Pty. Ltd. | Photodynamic therapeutic compounds and photodynamic methods of treatment |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648485A (en) * | 1994-10-26 | 1997-07-15 | University Of British Columbia | β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
US6376483B1 (en) * | 1999-05-27 | 2002-04-23 | Miravant Pharmaceuticals, Inc. | Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production |
-
1994
- 1994-10-26 US US08/329,577 patent/US5648485A/en not_active Expired - Fee Related
-
1995
- 1995-10-25 PT PT95944791T patent/PT804439E/pt unknown
- 1995-10-25 ES ES95944791T patent/ES2208701T3/es not_active Expired - Lifetime
- 1995-10-25 CZ CZ19971155A patent/CZ294496B6/cs not_active IP Right Cessation
- 1995-10-25 HU HU9701702A patent/HU221102B1/hu not_active IP Right Cessation
- 1995-10-25 AU AU36951/95A patent/AU704971B2/en not_active Ceased
- 1995-10-25 KR KR1019970702735A patent/KR970707129A/ko active IP Right Grant
- 1995-10-25 CA CA002199399A patent/CA2199399C/en not_active Expired - Fee Related
- 1995-10-25 DE DE69531795T patent/DE69531795T2/de not_active Expired - Fee Related
- 1995-10-25 EP EP95944791A patent/EP0804439B1/en not_active Expired - Lifetime
- 1995-10-25 JP JP51420596A patent/JP3228296B2/ja not_active Expired - Fee Related
- 1995-10-25 NZ NZ294203A patent/NZ294203A/xx not_active IP Right Cessation
- 1995-10-25 WO PCT/CA1995/000602 patent/WO1996013504A1/en active IP Right Grant
- 1995-10-25 DK DK95944791T patent/DK0804439T3/da active
- 1995-10-25 AT AT95944791T patent/ATE250064T1/de not_active IP Right Cessation
- 1995-10-25 PL PL95319907A patent/PL182239B1/pl not_active IP Right Cessation
- 1995-10-25 CN CN95195859A patent/CN1043143C/zh not_active Expired - Fee Related
- 1995-12-08 TW TW084113113A patent/TW301648B/zh active
-
1997
- 1997-04-23 FI FI971734A patent/FI971734A/fi not_active Application Discontinuation
- 1997-04-25 NO NO971952A patent/NO308411B1/no not_active IP Right Cessation
- 1997-05-08 US US08/853,115 patent/US5831088A/en not_active Expired - Fee Related
-
2001
- 2001-03-28 JP JP2001094418A patent/JP2001294589A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NO971952L (no) | 1997-04-25 |
US5831088A (en) | 1998-11-03 |
AU3695195A (en) | 1996-05-23 |
CZ294496B6 (cs) | 2005-01-12 |
PL182239B1 (pl) | 2001-11-30 |
NO308411B1 (no) | 2000-09-11 |
JP3228296B2 (ja) | 2001-11-12 |
JP2001294589A (ja) | 2001-10-23 |
CN1043143C (zh) | 1999-04-28 |
CA2199399A1 (en) | 1996-05-09 |
FI971734A0 (fi) | 1997-04-23 |
DE69531795T2 (de) | 2004-08-05 |
MX9703013A (es) | 1997-07-31 |
HUT77008A (hu) | 1998-03-02 |
WO1996013504A1 (en) | 1996-05-09 |
KR970707129A (ko) | 1997-12-01 |
NO971952D0 (no) | 1997-04-25 |
ES2208701T3 (es) | 2004-06-16 |
CA2199399C (en) | 2004-02-24 |
TW301648B (ja) | 1997-04-01 |
PL319907A1 (en) | 1997-09-01 |
JPH10507766A (ja) | 1998-07-28 |
EP0804439B1 (en) | 2003-09-17 |
FI971734A (fi) | 1997-04-23 |
CN1161697A (zh) | 1997-10-08 |
CZ115597A3 (en) | 1997-09-17 |
AU704971B2 (en) | 1999-05-13 |
PT804439E (pt) | 2004-02-27 |
US5648485A (en) | 1997-07-15 |
ATE250064T1 (de) | 2003-10-15 |
NZ294203A (en) | 1998-12-23 |
EP0804439A1 (en) | 1997-11-05 |
HU221102B1 (en) | 2002-08-28 |
DE69531795D1 (de) | 2003-10-23 |
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