DK0727416T3 - Substituerede benzensulfonylurinstoffer og -thiourinstoffer, og fremgangsmåde til deres fremstilling, deres anvendelse som - Google Patents

Substituerede benzensulfonylurinstoffer og -thiourinstoffer, og fremgangsmåde til deres fremstilling, deres anvendelse som

Info

Publication number: DK0727416T3
Authority: DK; Denmark
Prior art keywords: thioureas; preparation; substituted benzenesulfonylureas; benzenesulfonylureas; substituted
Prior art date: 1995-02-17

Application number

DK96101976T

Other languages

English (en)

Inventor

Heinrich Christian Dr Englert

Uwe Dr Gerlach

Dr Mania Dieter

Heinz Dr Goegelein

Joachim Dr Kaiser

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-17

Filing date

1996-02-12

Publication date

2000-06-13

1996-02-12 Application filed by Hoechst Ag filed Critical Hoechst Ag

2000-06-13 Application granted granted Critical

2000-06-13 Publication of DK0727416T3 publication Critical patent/DK0727416T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK96101976T 1995-02-17 1996-02-12 Substituerede benzensulfonylurinstoffer og -thiourinstoffer, og fremgangsmåde til deres fremstilling, deres anvendelse som DK0727416T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19505397A DE19505397A1 (de)	1995-02-17	1995-02-17	Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number	Publication Date
DK0727416T3 true DK0727416T3 (da)	2000-06-13

Family

ID=7754249

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96101976T DK0727416T3 (da)	1995-02-17	1996-02-12	Substituerede benzensulfonylurinstoffer og -thiourinstoffer, og fremgangsmåde til deres fremstilling, deres anvendelse som

Country Status (32)

Country	Link
US (1)	US5652268A (da)
EP (1)	EP0727416B1 (da)
JP (1)	JP3905568B2 (da)
KR (1)	KR100450914B1 (da)
CN (1)	CN1058705C (da)
AR (1)	AR003924A1 (da)
AT (1)	ATE189213T1 (da)
AU (1)	AU700793B2 (da)
BR (1)	BR9600778A (da)
CA (1)	CA2169694C (da)
CY (1)	CY2220B1 (da)
CZ (1)	CZ291271B6 (da)
DE (2)	DE19505397A1 (da)
DK (1)	DK0727416T3 (da)
ES (1)	ES2143675T3 (da)
FI (1)	FI120393B (da)
GR (1)	GR3033049T3 (da)
HK (1)	HK1011965A1 (da)
HR (1)	HRP960077B1 (da)
HU (1)	HU226463B1 (da)
IL (1)	IL117150A (da)
MY (1)	MY113431A (da)
NO (1)	NO305751B1 (da)
NZ (1)	NZ280991A (da)
PL (1)	PL181950B1 (da)
PT (1)	PT727416E (da)
RU (1)	RU2198163C2 (da)
SI (1)	SI9600049B (da)
SK (1)	SK281605B6 (da)
TR (1)	TR199600118A2 (da)
TW (1)	TW355183B (da)
ZA (1)	ZA961231B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19546736A1 (de) *	1995-12-14	1997-06-19	Hoechst Ag	Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
DE19647000A1 (de) *	1996-11-14	1998-05-20	Hoechst Ag	3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19832009A1 (de)	1998-07-16	2000-01-20	Hoechst Marion Roussel De Gmbh	2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
KR100981592B1 (ko) *	1998-09-10	2010-09-13	사노피-아벤티스 도이칠란트 게엠베하	벤젠설포닐(티오)우레아 또는 베타-수용체 차단제와 배합된 벤젠설포닐(티오)우레아를 포함하는 자율신경계 기능부전의 치료 또는 예방을 위한 약제학적 조성물
DE19917233A1 (de) *	1999-04-16	2000-10-19	Aventis Pharma Gmbh	Kristalline Formen des Natriumsalzes des 5-Chlor-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonyl-phenyl)-ethyl)- benzamids
DE19923086A1 (de) *	1999-05-20	2000-11-23	Aventis Pharma Gmbh	Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054482A1 (de)	2000-11-03	2002-05-08	Aventis Pharma Gmbh	Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054481A1 (de)	2000-11-03	2002-05-08	Aventis Pharma Gmbh	Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10129704A1 (de) *	2001-06-22	2003-01-02	Aventis Pharma Gmbh	Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
DE102004061017A1 (de) *	2004-12-18	2006-06-22	Sanofi-Aventis Deutschland Gmbh	Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DK2164825T3 (da) *	2007-06-05	2014-07-14	Sanofi Sa	Di(hetero)arylcyclohexanderivater, deres fremstilling, deres anvendelse og terapeutiske præparater, der omfatter disse
WO2023020412A1 (zh) *	2021-08-16	2023-02-23	中国科学院上海药物研究所	磺酰脲化合物、制备方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1198354B (de) *	1963-09-25	1965-08-12	Hoechst Ag	Verfahren zur Herstellung von Benzol-sulfonylharnstoffen
DE1518874C3 (de) *	1964-10-07	1975-03-13	Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt	Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
BE754454A (fr) *	1969-08-06	1971-02-05	Bayer Ag	Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
DE2413514C3 (de) *	1974-03-21	1982-03-04	Hoechst Ag, 6000 Frankfurt	N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung
ATE146775T1 (de) *	1993-02-23	1997-01-15	Hoechst Ag	Substituierte benzolsulfonylharnstoffe und - thioharnstoffe- verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika

1995
- 1995-02-17 DE DE19505397A patent/DE19505397A1/de not_active Withdrawn
- 1995-12-28 HU HU9503879A patent/HU226463B1/hu not_active IP Right Cessation
1996
- 1996-01-29 PL PL96312528A patent/PL181950B1/pl not_active IP Right Cessation
- 1996-02-12 PT PT96101976T patent/PT727416E/pt unknown
- 1996-02-12 ES ES96101976T patent/ES2143675T3/es not_active Expired - Lifetime
- 1996-02-12 TW TW085101695A patent/TW355183B/zh not_active IP Right Cessation
- 1996-02-12 DK DK96101976T patent/DK0727416T3/da active
- 1996-02-12 AT AT96101976T patent/ATE189213T1/de active
- 1996-02-12 DE DE59604262T patent/DE59604262D1/de not_active Expired - Lifetime
- 1996-02-12 EP EP96101976A patent/EP0727416B1/de not_active Expired - Lifetime
- 1996-02-14 CN CN96102016A patent/CN1058705C/zh not_active Expired - Fee Related
- 1996-02-14 CZ CZ1996436A patent/CZ291271B6/cs not_active IP Right Cessation
- 1996-02-15 SK SK211-96A patent/SK281605B6/sk not_active IP Right Cessation
- 1996-02-15 AR ARP960101392A patent/AR003924A1/es unknown
- 1996-02-15 TR TR96/00118A patent/TR199600118A2/xx unknown
- 1996-02-15 NZ NZ280991A patent/NZ280991A/en not_active IP Right Cessation
- 1996-02-15 FI FI960689A patent/FI120393B/fi not_active IP Right Cessation
- 1996-02-15 AU AU45560/96A patent/AU700793B2/en not_active Ceased
- 1996-02-15 IL IL11715096A patent/IL117150A/xx not_active IP Right Cessation
- 1996-02-15 US US08/602,053 patent/US5652268A/en not_active Expired - Lifetime
- 1996-02-15 HR HR960077A patent/HRP960077B1/xx not_active IP Right Cessation
- 1996-02-16 KR KR1019960003824A patent/KR100450914B1/ko not_active IP Right Cessation
- 1996-02-16 MY MYPI96000623A patent/MY113431A/en unknown
- 1996-02-16 CA CA002169694A patent/CA2169694C/en not_active Expired - Fee Related
- 1996-02-16 BR BR9600778A patent/BR9600778A/pt not_active Application Discontinuation
- 1996-02-16 JP JP02905396A patent/JP3905568B2/ja not_active Expired - Fee Related
- 1996-02-16 RU RU96102869/04A patent/RU2198163C2/ru not_active IP Right Cessation
- 1996-02-16 SI SI9600049A patent/SI9600049B/sl not_active IP Right Cessation
- 1996-02-16 ZA ZA961231A patent/ZA961231B/xx unknown
- 1996-02-16 NO NO960627A patent/NO305751B1/no not_active IP Right Cessation
1998
- 1998-12-12 HK HK98113240A patent/HK1011965A1/xx not_active IP Right Cessation
2000
- 2000-03-24 GR GR20000400736T patent/GR3033049T3/el unknown
2001
- 2001-05-03 CY CY0100006A patent/CY2220B1/xx unknown

Also Published As

Publication number	Publication date
CA2169694C (en)	2008-05-20
HU226463B1 (en)	2008-12-29
ZA961231B (en)	1996-08-27
TW355183B (en)	1999-04-01
SI9600049B (en)	2001-12-31
GR3033049T3 (en)	2000-08-31
BR9600778A (pt)	1997-12-23
NO960627D0 (no)	1996-02-16
CN1134414A (zh)	1996-10-30
HRP960077B1 (en)	2001-06-30
MY113431A (en)	2002-02-28
US5652268A (en)	1997-07-29
FI960689A (fi)	1996-08-18
DE59604262D1 (de)	2000-03-02
EP0727416A1 (de)	1996-08-21
PL312528A1 (en)	1996-08-19
DE19505397A1 (de)	1996-08-22
CN1058705C (zh)	2000-11-22
HK1011965A1 (en)	1999-07-23
SK281605B6 (sk)	2001-05-10
RU2198163C2 (ru)	2003-02-10
EP0727416B1 (de)	2000-01-26
ES2143675T3 (es)	2000-05-16
TR199600118A2 (tr)	1996-10-21
KR100450914B1 (ko)	2004-12-03
FI960689A0 (fi)	1996-02-15
PL181950B1 (pl)	2001-10-31
JPH08245554A (ja)	1996-09-24
IL117150A (en)	2001-03-19
CA2169694A1 (en)	1996-08-18
JP3905568B2 (ja)	2007-04-18
AU4556096A (en)	1996-08-29
AU700793B2 (en)	1999-01-14
NO960627L (no)	1996-08-19
SK21196A3 (en)	1996-10-02
KR960031433A (ko)	1996-09-17
HU9503879D0 (en)	1996-02-28
NZ280991A (en)	1997-01-29
FI120393B (fi)	2009-10-15
ATE189213T1 (de)	2000-02-15
CZ43696A3 (en)	1996-09-11
IL117150A0 (en)	1996-06-18
PT727416E (pt)	2000-06-30
SI9600049A (en)	1996-10-31
NO305751B1 (no)	1999-07-19
HRP960077A2 (en)	1997-12-31
AR003924A1 (es)	1998-09-30
CZ291271B6 (cs)	2003-01-15
CY2220B1 (en)	2003-04-18
HUT73973A (en)	1996-10-28

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NO952618L (no)	1996-01-02	Xerogeler, fremgangsmåte for fremstilling derav samt deres anvendelse
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NO941517L (no)	1994-10-28	2-amino-4-kinolin-dihydropyridiner, fremgangsmåter for deres fremstilling og deres anvendelse
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