DK0711280T3 - Perhydroisoindolderivater, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser - Google Patents

Perhydroisoindolderivater, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser

Info

Publication number
DK0711280T3
DK0711280T3 DK94923755T DK94923755T DK0711280T3 DK 0711280 T3 DK0711280 T3 DK 0711280T3 DK 94923755 T DK94923755 T DK 94923755T DK 94923755 T DK94923755 T DK 94923755T DK 0711280 T3 DK0711280 T3 DK 0711280T3
Authority
DK
Denmark
Prior art keywords
compounds
preparation
pharmaceutical compositions
compositions containing
pct
Prior art date
Application number
DK94923755T
Other languages
English (en)
Inventor
Daniel Achard
Serge Grisoni
Evelyne James-Surcouf
Jean-Luc Malleron
Anne Morgat
Michel Tabart
Jean-Francois Peyronel
Jean-Francois Sabuco
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9309400A external-priority patent/FR2709752B1/fr
Priority claimed from FR9311946A external-priority patent/FR2710913B1/fr
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0711280T3 publication Critical patent/DK0711280T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK94923755T 1993-07-30 1994-07-28 Perhydroisoindolderivater, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser DK0711280T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9309400A FR2709752B1 (fr) 1993-07-30 1993-07-30 Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR9311946A FR2710913B1 (fr) 1993-10-07 1993-10-07 Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1994/000952 WO1995004040A1 (fr) 1993-07-30 1994-07-28 Derives de perhydroisoindole comme antagonistes de la substance p

Publications (1)

Publication Number Publication Date
DK0711280T3 true DK0711280T3 (da) 1999-06-14

Family

ID=26230522

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94923755T DK0711280T3 (da) 1993-07-30 1994-07-28 Perhydroisoindolderivater, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser

Country Status (19)

Country Link
US (1) US5624950A (da)
EP (1) EP0711280B1 (da)
JP (1) JPH09500893A (da)
KR (1) KR960703858A (da)
AT (1) ATE171445T1 (da)
AU (1) AU7386594A (da)
CA (1) CA2168233A1 (da)
CZ (1) CZ26396A3 (da)
DE (1) DE69413542T2 (da)
DK (1) DK0711280T3 (da)
ES (1) ES2123149T3 (da)
FI (1) FI960399A0 (da)
HU (1) HUT75304A (da)
IL (1) IL110494A0 (da)
NO (1) NO960365D0 (da)
PL (1) PL312739A1 (da)
SK (1) SK13096A3 (da)
TW (1) TW365603B (da)
WO (1) WO1995004040A1 (da)

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ATE550019T1 (de) 2005-05-17 2012-04-15 Merck Sharp & Dohme Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
US7956050B2 (en) 2005-07-15 2011-06-07 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
EP1940842B1 (en) 2005-09-29 2012-05-30 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
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US7265247B1 (en) 2006-07-28 2007-09-04 Im&T Research, Inc. Substituted phenylsulfur trifluoride and other like fluorinating agents
EP2698157B1 (en) 2006-09-22 2015-05-20 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
EP2109608B1 (en) 2007-01-10 2011-03-23 Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
KR20140061493A (ko) 2007-03-23 2014-05-21 우베 인더스트리즈 리미티드 아릴설퍼 펜타플루오라이드의 제조공정
US8399720B2 (en) 2007-03-23 2013-03-19 Ube Industries, Ltd. Methods for producing fluorinated phenylsulfur pentafluorides
AU2008233662B2 (en) 2007-04-02 2012-08-23 Msd K.K. Indoledione derivative
US8389553B2 (en) 2007-06-27 2013-03-05 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
US8030516B2 (en) 2007-10-19 2011-10-04 Ube Industries, Ltd. Methods for producing perfluoroalkanedi(sulfonyl chloride)
CN102014631A (zh) 2008-03-03 2011-04-13 泰格尔医药科技公司 酪氨酸激酶抑制剂
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
EP2334661B1 (en) 2008-09-22 2017-08-30 Ube Industries, Ltd. Processes for preparing poly(pentafluorosulfanyl)aromatic compounds
US8203003B2 (en) 2009-01-09 2012-06-19 Ube Industries, Ltd. 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods
EP2413932A4 (en) 2009-04-01 2012-09-19 Merck Sharp & Dohme INHIBITORS OF AKT ACTIVITY
WO2010132437A1 (en) 2009-05-12 2010-11-18 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
JP5739415B2 (ja) 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用
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CN103068980B (zh) 2010-08-02 2017-04-05 瑟纳治疗公司 使用短干扰核酸（siNA）的RNA干扰介导的联蛋白（钙粘蛋白关联蛋白质），β1（CTNNB1）基因表达的抑制
KR102072631B1 (ko) 2010-08-17 2020-02-03 시르나 쎄러퓨틱스 인코퍼레이티드 짧은 간섭 핵산 （ｓｉＮＡ）을 사용한 Ｂ형 간염 바이러스 （ＨＢＶ） 유전자 발현의 ＲＮＡ 간섭 매개 억제
US8883801B2 (en) 2010-08-23 2014-11-11 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
WO2012030685A2 (en) 2010-09-01 2012-03-08 Schering Corporation Indazole derivatives useful as erk inhibitors
US9242981B2 (en) 2010-09-16 2016-01-26 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel ERK inhibitors
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ES2651347T3 (es) 2012-11-28 2018-01-25 Merck Sharp & Dohme Corp. Composiciones y métodos para el tratamiento del cáncer
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Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2654726B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone et leur preparation.
FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2676443B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole et leur preparation.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.
FR2689888B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
EP0711280A1 (fr) 1996-05-15
NO960365L (no) 1996-01-29
HU9503986D0 (en) 1996-03-28
ATE171445T1 (de) 1998-10-15
DE69413542T2 (de) 1999-03-25
HUT75304A (en) 1997-05-28
KR960703858A (ko) 1996-08-31
AU7386594A (en) 1995-02-28
DE69413542D1 (de) 1998-10-29
PL312739A1 (en) 1996-05-13
IL110494A0 (en) 1994-10-21
FI960399A (fi) 1996-01-29
WO1995004040A1 (fr) 1995-02-09
JPH09500893A (ja) 1997-01-28
FI960399A0 (fi) 1996-01-29
CZ26396A3 (en) 1996-05-15
ES2123149T3 (es) 1999-01-01
CA2168233A1 (fr) 1995-02-09
SK13096A3 (en) 1996-09-04
US5624950A (en) 1997-04-29
TW365603B (en) 1999-08-01
NO960365D0 (no) 1996-01-29
EP0711280B1 (fr) 1998-09-23

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