ATE171445T1 - Perhydroisoindolderivate als substanz p antagonisten - Google Patents

Perhydroisoindolderivate als substanz p antagonisten

Info

Publication number
ATE171445T1
ATE171445T1 AT94923755T AT94923755T ATE171445T1 AT E171445 T1 ATE171445 T1 AT E171445T1 AT 94923755 T AT94923755 T AT 94923755T AT 94923755 T AT94923755 T AT 94923755T AT E171445 T1 ATE171445 T1 AT E171445T1
Authority
AT
Austria
Prior art keywords
antagonists
substance
pct
derivatives
perhydroisoindole derivatives
Prior art date
Application number
AT94923755T
Other languages
English (en)
Inventor
Daniel Achard
Serge Grisoni
Evelyne James-Surcouf
Jean-Luc Malleron
Anne Morgat
Jean-Francois Peyronel
Jean-Francois Sabuco
Michel Tabart
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9309400A external-priority patent/FR2709752B1/fr
Priority claimed from FR9311946A external-priority patent/FR2710913B1/fr
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of ATE171445T1 publication Critical patent/ATE171445T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT94923755T 1993-07-30 1994-07-28 Perhydroisoindolderivate als substanz p antagonisten ATE171445T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9309400A FR2709752B1 (fr) 1993-07-30 1993-07-30 Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR9311946A FR2710913B1 (fr) 1993-10-07 1993-10-07 Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE171445T1 true ATE171445T1 (de) 1998-10-15

Family

ID=26230522

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94923755T ATE171445T1 (de) 1993-07-30 1994-07-28 Perhydroisoindolderivate als substanz p antagonisten

Country Status (19)

Country Link
US (1) US5624950A (de)
EP (1) EP0711280B1 (de)
JP (1) JPH09500893A (de)
KR (1) KR960703858A (de)
AT (1) ATE171445T1 (de)
AU (1) AU7386594A (de)
CA (1) CA2168233A1 (de)
CZ (1) CZ26396A3 (de)
DE (1) DE69413542T2 (de)
DK (1) DK0711280T3 (de)
ES (1) ES2123149T3 (de)
FI (1) FI960399A (de)
HU (1) HUT75304A (de)
IL (1) IL110494A0 (de)
NO (1) NO960365D0 (de)
PL (1) PL312739A1 (de)
SK (1) SK13096A3 (de)
TW (1) TW365603B (de)
WO (1) WO1995004040A1 (de)

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US8362075B2 (en) 2005-05-17 2013-01-29 Merck Sharp & Dohme Corp. Cyclohexyl sulphones for treatment of cancer
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WO2007041052A2 (en) 2005-09-29 2007-04-12 Merck & Co., Inc. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
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US7265247B1 (en) 2006-07-28 2007-09-04 Im&T Research, Inc. Substituted phenylsulfur trifluoride and other like fluorinating agents
WO2008039327A2 (en) 2006-09-22 2008-04-03 Merck & Co., Inc. Method of treatment using fatty acid synthesis inhibitors
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
WO2008084261A1 (en) 2007-01-10 2008-07-17 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
US8399720B2 (en) 2007-03-23 2013-03-19 Ube Industries, Ltd. Methods for producing fluorinated phenylsulfur pentafluorides
CA2857831C (en) 2007-03-23 2017-01-03 Ube Industries, Ltd. Process for producing arylsulfur pentafluorides
US8106086B2 (en) 2007-04-02 2012-01-31 Msd K.K. Indoledione derivative
EP2170076B1 (de) 2007-06-27 2016-05-18 Merck Sharp & Dohme Corp. 4-carboxybenzylamino-derivate als histondeacetylase-hemmer
US8030516B2 (en) 2007-10-19 2011-10-04 Ube Industries, Ltd. Methods for producing perfluoroalkanedi(sulfonyl chloride)
CA2717509A1 (en) 2008-03-03 2009-09-11 Tiger Pharmatech Tyrosine kinase inhibitors
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
US8653302B2 (en) 2008-09-22 2014-02-18 Ube Industries, Ltd. Processes for preparing poly(pentafluorosulfanyl)aromatic compounds
WO2010081014A1 (en) 2009-01-09 2010-07-15 Im&T Research, Inc. Novel 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
ES2446971T3 (es) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
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EP2608669B1 (de) 2010-08-23 2016-06-22 Merck Sharp & Dohme Corp. Neue pyrazolo-[1,5-a-]pyrimidinderivate als mtor-hemmer
WO2012030685A2 (en) 2010-09-01 2012-03-08 Schering Corporation Indazole derivatives useful as erk inhibitors
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Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2654726B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone et leur preparation.
FR2676443B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole et leur preparation.
FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689888B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.

Also Published As

Publication number Publication date
AU7386594A (en) 1995-02-28
EP0711280A1 (de) 1996-05-15
US5624950A (en) 1997-04-29
FI960399A0 (fi) 1996-01-29
JPH09500893A (ja) 1997-01-28
ES2123149T3 (es) 1999-01-01
FI960399A (fi) 1996-01-29
DK0711280T3 (da) 1999-06-14
CZ26396A3 (en) 1996-05-15
DE69413542T2 (de) 1999-03-25
NO960365L (no) 1996-01-29
HUT75304A (en) 1997-05-28
EP0711280B1 (de) 1998-09-23
HU9503986D0 (en) 1996-03-28
IL110494A0 (en) 1994-10-21
SK13096A3 (en) 1996-09-04
KR960703858A (ko) 1996-08-31
DE69413542D1 (de) 1998-10-29
NO960365D0 (no) 1996-01-29
TW365603B (en) 1999-08-01
WO1995004040A1 (fr) 1995-02-09
PL312739A1 (en) 1996-05-13
CA2168233A1 (fr) 1995-02-09

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee