DE69433984D1 - Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d - Google Patents
Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1dInfo
- Publication number
- DE69433984D1 DE69433984D1 DE69433984T DE69433984T DE69433984D1 DE 69433984 D1 DE69433984 D1 DE 69433984D1 DE 69433984 T DE69433984 T DE 69433984T DE 69433984 T DE69433984 T DE 69433984T DE 69433984 D1 DE69433984 D1 DE 69433984D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- ht1d
- ht1b
- indol
- ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9313875 | 1993-11-19 | ||
FR9313875A FR2712591B1 (fr) | 1993-11-19 | 1993-11-19 | Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique. |
PCT/FR1994/001343 WO1995014004A1 (fr) | 1993-11-19 | 1994-11-17 | Arylpiperazines derivees d'indole comme ligands pour les recepteurs 5 ht1-like 5 ht1b et 5 ht1d |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69433984D1 true DE69433984D1 (de) | 2004-10-14 |
DE69433984T2 DE69433984T2 (de) | 2005-09-22 |
Family
ID=9453051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69433984T Expired - Fee Related DE69433984T2 (de) | 1993-11-19 | 1994-11-17 | Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d |
Country Status (12)
Country | Link |
---|---|
US (1) | US5726177A (de) |
EP (1) | EP0729455B1 (de) |
JP (1) | JP3553071B2 (de) |
AT (1) | ATE275545T1 (de) |
AU (1) | AU686278B2 (de) |
CA (1) | CA2176935C (de) |
DE (1) | DE69433984T2 (de) |
ES (1) | ES2227541T3 (de) |
FR (1) | FR2712591B1 (de) |
NZ (1) | NZ276444A (de) |
PT (1) | PT729455E (de) |
WO (1) | WO1995014004A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2434297A (en) * | 1996-05-23 | 1997-12-09 | Alcon Laboratories, Inc. | The use of 5-ht1b/1d agonists to treat ocular pain |
FR2749846B1 (fr) * | 1996-06-17 | 1998-09-11 | Pf Medicament | Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique |
DE19734665A1 (de) | 1997-08-11 | 1999-02-18 | Bayer Ag | Mittel gegen holzzerstörende Insekten |
FR2767527B1 (fr) * | 1997-08-25 | 1999-11-12 | Pf Medicament | Derives de piperazines indoliques, utiles comme medicaments et procede de preparation |
US6589954B1 (en) | 1998-05-22 | 2003-07-08 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6340685B1 (en) * | 1998-05-22 | 2002-01-22 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6448257B1 (en) | 1998-05-22 | 2002-09-10 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6867209B1 (en) | 1998-05-22 | 2005-03-15 | Scios, Inc. | Indole-type derivatives as inhibitors of p38 kinase |
US6362371B1 (en) * | 1998-06-08 | 2002-03-26 | Advanced Medicine, Inc. | β2- adrenergic receptor agonists |
EP1083918A1 (de) * | 1998-06-08 | 2001-03-21 | Advanced Medicine, Inc. | Neue therapeutische substanzen die die 5-ht-rezeptoren modulieren |
US6143569A (en) * | 1998-08-31 | 2000-11-07 | The United States Of America As Represented By The Secretary Of The Navy | Chelators exhibiting triple fluorescence |
IL146309A (en) | 1999-05-21 | 2008-03-20 | Scios Inc | Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38 |
TR200201683T2 (tr) * | 1999-12-30 | 2002-12-23 | H. Lundbeck A/S | İkameli fenil-piperazin türevleri, bunların hazırlanması ve kullanımları |
GB0013378D0 (en) * | 2000-06-01 | 2000-07-26 | Glaxo Group Ltd | Use of therapeutic benzamide derivatives |
ITRM20010356A1 (it) * | 2001-06-21 | 2002-12-23 | Sigma Tau Ind Farmaceuti | "5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina. |
FR2827287B1 (fr) * | 2001-07-13 | 2003-10-31 | Servier Lab | Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
DE10217006A1 (de) * | 2002-04-16 | 2003-11-06 | Merck Patent Gmbh | Substituierte Indole |
CA2495383A1 (en) | 2002-08-12 | 2004-02-26 | Takeda Pharmaceutical Company Limited | Fused benzene derivative and use |
GB0305575D0 (en) * | 2003-03-11 | 2003-04-16 | Glaxo Group Ltd | Novel compounds |
US20050065202A1 (en) * | 2003-05-09 | 2005-03-24 | Vidal Ramon Merce | Use of sulphonamide derivatives for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion |
EP1676842A1 (de) * | 2004-12-30 | 2006-07-05 | Laboratorios Del Dr. Esteve, S.A. | Nitrosubstituierte Phenylpiperazinverbindungen, ihre Herstellung und Verwendung in Arzneimitteln |
CN101679261A (zh) * | 2007-03-09 | 2010-03-24 | 阿斯利康(瑞典)有限公司 | 哌嗪和哌啶mGluR5增效剂 |
US7776138B2 (en) * | 2008-06-12 | 2010-08-17 | Conocophillips Company | Removal of contaminants from gas streams |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8614287D0 (en) * | 1986-06-12 | 1986-07-16 | Glaxo Group Ltd | Chemical compounds |
US4883795A (en) * | 1988-01-22 | 1989-11-28 | Pfizer Inc. | Piperazinyl-heterocyclic compounds |
DE4101686A1 (de) * | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
DE4127849A1 (de) * | 1991-08-22 | 1993-02-25 | Merck Patent Gmbh | Benzodioxanderivate |
GB9216009D0 (en) * | 1992-07-28 | 1992-09-09 | Almirall Lab | New indol derivatives |
FR2699918B1 (fr) * | 1992-12-30 | 1995-03-17 | Pf Medicament | Ligands sélectifs des récepteurs 5HY1D-5HT1B dérivés d'indole-pipérazine utiles comme médicaments. |
DE4333254A1 (de) * | 1993-09-30 | 1995-04-06 | Merck Patent Gmbh | Piperidine und Piperazine |
-
1993
- 1993-11-19 FR FR9313875A patent/FR2712591B1/fr not_active Expired - Fee Related
-
1994
- 1994-11-17 JP JP51426795A patent/JP3553071B2/ja not_active Expired - Fee Related
- 1994-11-17 CA CA002176935A patent/CA2176935C/fr not_active Expired - Fee Related
- 1994-11-17 ES ES95901501T patent/ES2227541T3/es not_active Expired - Lifetime
- 1994-11-17 EP EP95901501A patent/EP0729455B1/de not_active Expired - Lifetime
- 1994-11-17 DE DE69433984T patent/DE69433984T2/de not_active Expired - Fee Related
- 1994-11-17 US US08/648,091 patent/US5726177A/en not_active Expired - Fee Related
- 1994-11-17 NZ NZ276444A patent/NZ276444A/en not_active IP Right Cessation
- 1994-11-17 AU AU10708/95A patent/AU686278B2/en not_active Ceased
- 1994-11-17 WO PCT/FR1994/001343 patent/WO1995014004A1/fr active IP Right Grant
- 1994-11-17 PT PT95901501T patent/PT729455E/pt unknown
- 1994-11-17 AT AT95901501T patent/ATE275545T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0729455A1 (de) | 1996-09-04 |
PT729455E (pt) | 2005-01-31 |
ATE275545T1 (de) | 2004-09-15 |
FR2712591A1 (fr) | 1995-05-24 |
AU686278B2 (en) | 1998-02-05 |
JPH09505072A (ja) | 1997-05-20 |
FR2712591B1 (fr) | 1996-02-09 |
JP3553071B2 (ja) | 2004-08-11 |
ES2227541T3 (es) | 2005-04-01 |
WO1995014004A1 (fr) | 1995-05-26 |
AU1070895A (en) | 1995-06-06 |
NZ276444A (en) | 1998-02-26 |
CA2176935A1 (fr) | 1995-05-26 |
EP0729455B1 (de) | 2004-09-08 |
DE69433984T2 (de) | 2005-09-22 |
US5726177A (en) | 1998-03-10 |
CA2176935C (fr) | 2007-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |