DK0688206T3 - Vaccineleveringssystem og opbevaringsstabil forstadieopløsning til fjern indkapsling af aktive bestanddele - Google Patents

Vaccineleveringssystem og opbevaringsstabil forstadieopløsning til fjern indkapsling af aktive bestanddele

Info

Publication number
DK0688206T3
DK0688206T3 DK94909807T DK94909807T DK0688206T3 DK 0688206 T3 DK0688206 T3 DK 0688206T3 DK 94909807 T DK94909807 T DK 94909807T DK 94909807 T DK94909807 T DK 94909807T DK 0688206 T3 DK0688206 T3 DK 0688206T3
Authority
DK
Denmark
Prior art keywords
delivery system
vaccine delivery
pct
active ingredients
precursor solution
Prior art date
Application number
DK94909807T
Other languages
English (en)
Inventor
Michael W Fountain
Original Assignee
Fountain Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fountain Pharm Inc filed Critical Fountain Pharm Inc
Application granted granted Critical
Publication of DK0688206T3 publication Critical patent/DK0688206T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK94909807T 1993-02-26 1994-02-25 Vaccineleveringssystem og opbevaringsstabil forstadieopløsning til fjern indkapsling af aktive bestanddele DK0688206T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2397193A 1993-02-26 1993-02-26
PCT/US1994/002053 WO1994018950A1 (en) 1993-02-26 1994-02-25 Vaccine delivery system and shelf-stable precursor solution for remote encapsulation of active ingredients

Publications (1)

Publication Number Publication Date
DK0688206T3 true DK0688206T3 (da) 2000-09-25

Family

ID=21818176

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94909807T DK0688206T3 (da) 1993-02-26 1994-02-25 Vaccineleveringssystem og opbevaringsstabil forstadieopløsning til fjern indkapsling af aktive bestanddele

Country Status (13)

Country Link
US (1) US5879703A (da)
EP (1) EP0688206B1 (da)
JP (1) JPH08507077A (da)
AT (1) ATE192331T1 (da)
AU (1) AU677826B2 (da)
CA (1) CA2157125A1 (da)
DE (1) DE69424279T2 (da)
DK (1) DK0688206T3 (da)
ES (1) ES2145132T3 (da)
HK (1) HK1012991A1 (da)
PT (1) PT688206E (da)
SG (1) SG44911A1 (da)
WO (1) WO1994018950A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
EP1754488A1 (en) 1999-05-24 2007-02-21 Introgen Therapeutics, Inc. Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
US10293056B1 (en) 2000-05-24 2019-05-21 Board Of Regents, The University Of Texas System Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
ES2625111T3 (es) * 2005-12-30 2017-07-18 Nuvessl Inc. Partículas nanolipídicas
US20140271782A1 (en) 2013-03-15 2014-09-18 Dermazone Solutions, Inc. Method for preparing nanolipids with encapsulated alcohol
WO2007092944A2 (en) * 2006-02-08 2007-08-16 Introgen Therapeutics, Inc. Compositions and methods involving gene therapy and proteasome modulation
US20140335166A1 (en) * 2013-05-08 2014-11-13 Michael W. Fountain Methods of Making and Using Nano Scale Particles
CN102066937A (zh) 2008-01-25 2011-05-18 P53股份有限公司 P53生物标记物
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
CA2767392C (en) 2009-07-06 2017-03-14 Variation Biotechnologies, Inc. Methods for preparing vesicles and formulations produced therefrom
US9907746B2 (en) 2009-07-06 2018-03-06 Variation Biotechnologies, Inc. Methods for preparing vesicles and formulations produced therefrom
CA2840079C (en) 2010-07-06 2018-07-03 Variation Biotechnologies Inc. Compositions and methods for treating influenza
US20130323280A1 (en) * 2011-01-13 2013-12-05 Variation Biotechnologies, Inc. Methods for preparing vesicles and formulations produced therefrom
MX359103B (es) 2011-01-13 2018-09-14 Variation Biotechnologies Inc Composiciones y sus usos en el tratamiento de infecciones virales.
US9333675B2 (en) * 2012-01-10 2016-05-10 Hzo, Inc. Profiles for precursors to polymeric materials
WO2013104995A2 (en) 2012-01-12 2013-07-18 Variation Biotechnologies, Inc. Compositions and methods for treating viral infections
WO2013111012A2 (en) 2012-01-27 2013-08-01 Variation Biotechnologies, Inc. Methods and compositions for therapeutic agents
US11298318B2 (en) 2015-04-13 2022-04-12 Fountain Technologies International, Llc One-step method for production of ultra-small lipid structures
US20200078427A1 (en) 2018-09-06 2020-03-12 NuVessl, Inc. Cannabis Sativa Derived Formulation for Transmucosal and Transdermal Delivery
US20200188298A1 (en) 2018-12-14 2020-06-18 NuVessl, Inc. Method For Using Composition With Enhanced Passenger Molecule Loading

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1695599A (en) * 1927-05-24 1928-12-18 Edward L Merzoian Dispenser
US2261877A (en) * 1940-05-15 1941-11-04 John G Erickson Dispensing device
US2712400A (en) * 1952-04-28 1955-07-05 Wayne C Stauffer Dispensing means for paste tubes
US3780911A (en) * 1972-01-03 1973-12-25 D Paige Dispensing apparatus for collapsible tube container
AU549154B2 (en) * 1982-12-07 1986-01-16 Motion, J.A.C. Collapsible tube expressor
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4755375A (en) * 1984-01-27 1988-07-05 Associated Universities, Inc. Method and kit for the selective labeling of red blood cells in whole blood with TC-99M
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
ES2039229T3 (es) * 1986-01-14 1993-09-16 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Procedimiento para la preparacion de complejos inmunogenicos y composiciones farmaceuticas que contienen estos complejos.
US5049388A (en) * 1986-11-06 1991-09-17 Research Development Foundation Small particle aerosol liposome and liposome-drug combinations for medical use
US5133965A (en) * 1988-06-08 1992-07-28 Fountain Pharmaceuticals, Inc. Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution
CA1340241C (en) * 1988-06-08 1998-12-15 Fountain Pharmaceuticals, Inc. Method for marking solvent dilution microcarriers
US5269979A (en) * 1988-06-08 1993-12-14 Fountain Pharmaceuticals, Inc. Method for making solvent dilution microcarriers
NZ230424A (en) * 1988-08-25 1992-05-26 Liposome Co Inc Liposomal composition comprising an externally disposed antigen
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
DE4136553A1 (de) * 1991-11-06 1993-05-13 Biotechnolog Forschung Gmbh Impfstoff gegen schleimhauterreger und herstellungsverfahren

Also Published As

Publication number Publication date
EP0688206A1 (en) 1995-12-27
US5879703A (en) 1999-03-09
AU677826B2 (en) 1997-05-08
DE69424279T2 (de) 2000-12-21
AU6250694A (en) 1994-09-14
JPH08507077A (ja) 1996-07-30
PT688206E (pt) 2000-08-31
HK1012991A1 (en) 1999-08-13
CA2157125A1 (en) 1994-09-01
WO1994018950A1 (en) 1994-09-01
SG44911A1 (en) 1997-12-19
DE69424279D1 (de) 2000-06-08
ATE192331T1 (de) 2000-05-15
ES2145132T3 (es) 2000-07-01
EP0688206B1 (en) 2000-05-03

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