DK0552192T3 - Forbedret tangentialstrømningsfiltreringsfremgangsmåde og -apparat - Google Patents

Forbedret tangentialstrømningsfiltreringsfremgangsmåde og -apparat

Info

Publication number
DK0552192T3
DK0552192T3 DK91917291.6T DK91917291T DK0552192T3 DK 0552192 T3 DK0552192 T3 DK 0552192T3 DK 91917291 T DK91917291 T DK 91917291T DK 0552192 T3 DK0552192 T3 DK 0552192T3
Authority
DK
Denmark
Prior art keywords
flow filtration
tangential flow
filtration method
improved tangential
flux
Prior art date
Application number
DK91917291.6T
Other languages
English (en)
Inventor
Robert D Van Reis
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0552192T3 publication Critical patent/DK0552192T3/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/145Ultrafiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/145Ultrafiltration
    • B01D61/146Ultrafiltration comprising multiple ultrafiltration steps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/147Microfiltration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/58Reaction vessels connected in series or in parallel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Cyclones (AREA)
  • Combined Means For Separation Of Solids (AREA)
DK91917291.6T 1990-09-17 1991-09-11 Forbedret tangentialstrømningsfiltreringsfremgangsmåde og -apparat DK0552192T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/583,886 US5256294A (en) 1990-09-17 1990-09-17 Tangential flow filtration process and apparatus

Publications (1)

Publication Number Publication Date
DK0552192T3 true DK0552192T3 (da) 1995-07-17

Family

ID=24334996

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91917291.6T DK0552192T3 (da) 1990-09-17 1991-09-11 Forbedret tangentialstrømningsfiltreringsfremgangsmåde og -apparat

Country Status (10)

Country Link
US (2) US5256294A (da)
EP (1) EP0552192B1 (da)
JP (2) JP3828143B2 (da)
AT (1) ATE119063T1 (da)
CA (1) CA2089663C (da)
DE (1) DE69107855T2 (da)
DK (1) DK0552192T3 (da)
ES (1) ES2072017T3 (da)
LV (1) LV11283B (da)
WO (1) WO1992004970A1 (da)

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256294A (en) * 1990-09-17 1993-10-26 Genentech, Inc. Tangential flow filtration process and apparatus
DE4143639C2 (de) * 1991-12-02 2002-10-24 Qiagen Gmbh Verfahren zur Isolierung und Reinigung von Nukleinsäuren
FR2693474B1 (fr) * 1992-07-09 1994-08-26 Daniel Garin Procédé et dispositif de séparation et de concentration de microorganismes contaminants.
US5705634A (en) * 1995-03-02 1998-01-06 Perimmune Holdings, Inc. High yield preparation of dimeric to decameric chitin oligomers
US6359114B1 (en) * 1995-06-07 2002-03-19 Aphton Corp. System for method for the modification and purification of proteins
AU712213B2 (en) * 1995-09-22 1999-11-04 Connaught Laboratories Limited Parainfluenza virus glycoproteins and vaccines
US6054051A (en) 1996-01-17 2000-04-25 Genentech, Inc. Tangential-flow filtration system
US6268487B1 (en) * 1996-05-13 2001-07-31 Genzyme Transgenics Corporation Purification of biologically active peptides from milk
US7026468B2 (en) * 1996-07-19 2006-04-11 Valentis, Inc. Process and equipment for plasmid purification
US7807822B2 (en) * 1996-08-01 2010-10-05 Robert Bridenbaugh Methods for purifying nucleic acids
US6022333A (en) * 1997-05-01 2000-02-08 S.L.I.M. Tech, Ltd. Method and system for removing materials from lymphatic and other fluids
US5919376A (en) * 1997-06-10 1999-07-06 Cae Ransohoff Inc. Filtration apparatus and method
US6265542B1 (en) 1997-10-24 2001-07-24 Genentech, Inc. Purification of molecules
US6077940A (en) * 1997-12-24 2000-06-20 Genentech, Inc. Free solution ligand interaction molecular separation method
JP2001000842A (ja) * 1998-05-22 2001-01-09 Daicel Chem Ind Ltd 病原性原虫濃縮用モジュールおよび濃縮方法
DE69919701T2 (de) * 1998-06-01 2005-09-15 Genentech, Inc., South San Francisco Abtrennung von antikörper-monomeren von deren multimeren mittels ionaustausch-chromatographie
BR9905868A (pt) * 1998-11-06 2001-01-23 Bio Sidus S A Procedimento de cultivo massivo de células de mamìfero para a obtenção de eritropoetina humana, recombinante e a eritropoetina humana recombinante obtida com tal procedimento
US7316780B1 (en) * 1999-01-29 2008-01-08 Pall Corporation Range separation devices and processes
DK1189935T3 (da) * 1999-06-25 2009-02-09 Wyeth Corp Ekstraktion af integrale membranproteiner
CA2378944A1 (en) 1999-07-23 2001-02-01 Genentech, Inc. Method for rnase- and organic solvent-free plasmid dna purification using tangential flow filtration
US7108791B2 (en) * 1999-09-14 2006-09-19 Millipore Corporation High-resolution virus removal methodology and filtration capsule useful therefor
US6296770B1 (en) 1999-12-09 2001-10-02 Eastman Kodak Company Constant concentration at the UF membrane wall UF process control and apparatus
DE10000196B4 (de) 2000-01-05 2013-10-10 Sartorius Stedim Biotech Gmbh Verbesserte Crossflow-Filtrationseinheit
US6607669B2 (en) * 2000-06-23 2003-08-19 Scilog, Inc. Method and apparatus for enhancing filtration yields in tangential flow filtration
GB0107634D0 (en) * 2001-03-27 2001-05-16 Fermentas Ab Nucleic acid purification
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
US20030171260A1 (en) * 2002-03-11 2003-09-11 Nelson Deanna Jean Compositions and methods utilizing hydroxamates to scavenge oxidant toxins
AU2003265235A1 (en) * 2002-04-26 2003-12-19 Genetech, Inc. Non-affinity purification of proteins
USRE49221E1 (en) 2002-06-14 2022-09-27 Parker Intangibles, Llc Single-use manifolds for automated, aseptic handling of solutions in bioprocessing applications
US6712963B2 (en) 2002-06-14 2004-03-30 Scilog, Llc Single-use manifold for automated, aseptic transfer of solutions in bioprocessing applications
US9283521B2 (en) 2002-06-14 2016-03-15 Parker-Hannifin Corporation Single-use manifold and sensors for automated, aseptic transfer of solutions in bioprocessing applications
ES2523366T3 (es) * 2002-06-19 2014-11-25 Northwest Biotherapeutics, Inc. Uso de un dispositivo de filtración de flujo tangencial y métodos para el enriquecimiento de leucocitos
AU2003248780A1 (en) * 2002-07-10 2004-01-23 Pall Corporation Hollow fiber membrane systems
CA2498518A1 (en) * 2002-09-13 2004-03-25 Valentis, Inc. Apparatus and method for preparative scale purification of nucleic acids
CN1759189A (zh) * 2003-02-24 2006-04-12 Gtc生物治疗学公司 切向流过滤方法及其装置
US7276163B2 (en) * 2003-10-01 2007-10-02 Ceramem Corporation Membrane devices with controlled transmembrane pressure and method of use
KR20070001927A (ko) * 2004-01-21 2007-01-04 도레이 가부시끼가이샤 분획 장치 및 분획 방법
FR2866899B1 (fr) * 2004-02-27 2006-06-09 Gervais Danone Sa Procede de production d'un concentrat liquide de bacteries adaptees et viables a usage alimentaire
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
JP2007525984A (ja) 2004-03-05 2007-09-13 ディーエスエム アイピー アセッツ ビー.ブイ. 連続的灌流および交互接線流による細胞培養の方法
EP1732660A4 (en) * 2004-03-29 2007-06-13 Pall Corp FOLDED CROSSFLOW FLUID TREATMENT ELEMENTS
WO2005113578A1 (en) * 2004-05-14 2005-12-01 New Jersey Institute Of Technology Highly selective membrane systems and methods for protein ultrafiltration
WO2005119126A1 (fr) * 2004-05-28 2005-12-15 Alstom Technology Ltd Dispositif a lit fluidise a agent comburant enrichi en oxygene
US20060043021A1 (en) 2004-09-02 2006-03-02 Millipore Corporation Port adapter for tangential flow filtration
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
CN101076347B (zh) * 2004-09-30 2012-09-26 拜耳医药保健有限公司 用于集成连续生产生物分子的装置和方法
AU2011203578B2 (en) * 2004-09-30 2012-10-11 Bayer Healthcare Llc Devices and methods for integrated continuous manufacturing of biological molecules
US20060130159A1 (en) * 2004-12-09 2006-06-15 Nick Masiello Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum
AU2006283726C1 (en) 2005-08-24 2015-05-07 Immunogen, Inc. Process for preparing maytansinoid antibody conjugates
WO2007038542A2 (en) * 2005-09-28 2007-04-05 Pall Corporation Fluid treatment assemblies and elements and methods for making them
CN101379182A (zh) * 2005-12-14 2009-03-04 器官发生有限公司 皮肤护理组合物以及处理
US7510654B2 (en) 2005-12-29 2009-03-31 Spf Innovations, Llc Method and apparatus for the filtration of biological samples
US7531632B2 (en) * 2006-02-16 2009-05-12 Gtc Biotherapeutics, Inc. Clarification of transgenic milk using depth filtration
BRPI0707027B1 (pt) 2006-02-24 2022-08-16 Toray Industries, Inc Método de fabricação de um produto químico e aparelho de fermentação contínua
BRPI0709693A2 (pt) 2006-03-31 2011-07-19 Genencor Int aparelhos de filtração de fluxo tangencial, sistemas, e processos para a separação de compostos
US20070240578A1 (en) * 2006-04-12 2007-10-18 Dileo Anthony Filter with memory, communication and temperature sensor
US20110094310A1 (en) * 2006-04-12 2011-04-28 Millipore Corporation Filter with memory, communication and pressure sensor
US20070243113A1 (en) 2006-04-12 2007-10-18 Dileo Anthony Filter with memory, communication and concentration sensor
US8007568B2 (en) * 2006-04-12 2011-08-30 Millipore Corporation Filter with memory, communication and pressure sensor
KR101685246B1 (ko) 2006-07-14 2016-12-09 디피엑스 홀딩스 비.브이. 개선된 세포 배양 방법
US7692041B2 (en) * 2006-08-07 2010-04-06 The University Of Montana Method of oxidation using nitric acid
US20090250653A1 (en) 2006-08-07 2009-10-08 Kiely Donald E Hydroxycarboxylic Acids and Salts
CN101269298B (zh) 2007-03-23 2011-06-01 中国科学院过程工程研究所 利用浓差极化浓缩生物大分子的膜过滤方法及其装置
WO2009010269A1 (en) * 2007-07-17 2009-01-22 F.Hoffmann-La Roche Ag Variable tangential flow filtration
PL2205343T3 (pl) * 2007-09-12 2013-12-31 Danisco Us Inc Filtracja z wewnętrzną kontrolą zanieczyszczeń
AU2008322438B2 (en) 2007-11-15 2014-06-19 The University Of Montana Hydroxypolyamide gel forming agents
CA2706403A1 (en) * 2007-11-29 2009-06-04 F. Hoffmann-La Roche Ag Immunoglobulin aggregates
US8043512B2 (en) * 2008-04-11 2011-10-25 Pall Corporation Fluid treatment arrangements and methods
SG157290A1 (en) * 2008-05-09 2009-12-29 Millipore Corp Method for reducing performance variability of multi-layer filters
US7895084B2 (en) * 2008-05-15 2011-02-22 Doapp, Inc. Method and system for providing purchasing on a wireless device
US8216473B2 (en) * 2008-06-13 2012-07-10 Solution Dynamics, Llc Apparatus and methods for solution processing using reverse osmosis
US8048315B2 (en) * 2008-07-28 2011-11-01 Pall Corporation Fluid treatment arrangements and methods
US9320761B2 (en) 2008-12-18 2016-04-26 Vivex Biomedical, Inc. Bone induction system and methods
JP6159528B2 (ja) * 2009-03-24 2017-07-05 ワイス・エルエルシー 高濃縮のタンパク質治療薬を生成するための膜蒸発
JP5697268B2 (ja) * 2009-09-29 2015-04-08 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft バッファー溶質のろ過前調整方法
US8119005B1 (en) * 2009-11-12 2012-02-21 Gabriel George Pinter Method and apparatus for partial desalination of a concentrated salt solution
WO2011091248A1 (en) * 2010-01-22 2011-07-28 Lonza Walkersville, Inc. High yield method and apparatus for volume reduction and washing of therapeutic cells using tangential flow filtration
CN101745316B (zh) * 2010-01-22 2011-12-28 中国科学院过程工程研究所 一种重力场辅助浓缩生物大分子的新型超滤方法及装置
PT2547222E (pt) * 2010-03-18 2014-07-25 Gea Mechanical Equipment Gmbh Instalação e processo para a filtração de bebidas
US8480978B2 (en) * 2010-08-12 2013-07-09 University Of Southern California Microfluidic fluid separator and related methods
WO2012065001A1 (en) 2010-11-11 2012-05-18 Rivertop Renewables Corrosion inhibiting composition
KR102027596B1 (ko) * 2010-12-06 2019-10-01 타폰 바이오시스템즈, 인코포레이티드 생물학적 산물을 위한 연속 처리 방법
RU2609417C2 (ru) 2011-04-21 2017-02-01 Ривертоп Реньюэблс, Инк. Связывающая кальций композиция
AU2012274016B2 (en) * 2011-12-13 2014-09-04 Cytiva Us Llc Membrane with localized asymmetries
US9266066B2 (en) * 2011-12-13 2016-02-23 Pall Corporation Membrane with localized asymmetries
WO2013126587A1 (en) * 2012-02-21 2013-08-29 Cytonics Corporation Systems, compositions, and methods for transplantation
EP2984467B1 (en) * 2012-10-18 2020-10-14 Innovaprep LLC Liquid to liquid biological particle fractionation and concentration
SI2914612T1 (sl) 2012-10-30 2019-03-29 F. Hoffmann-La Roche Ag Čiščenje polipeptidov z uporabo dvostopenjske tangencialne ultrafiltracije
EP2730330A1 (en) * 2012-11-09 2014-05-14 Tine SA Membrane filtration assembly and method of controlling trans-membrane pressure
EP2925826A1 (en) 2012-11-28 2015-10-07 Rivertop Renewables Corrosion inhibiting, freezing point lowering compositions
US9346736B2 (en) 2013-03-13 2016-05-24 Rivertop Renewables, Inc. Oxidation process
US9670124B2 (en) 2013-03-13 2017-06-06 Rivertop Renewables, Inc. Nitric acid oxidation process
WO2014159694A1 (en) 2013-03-13 2014-10-02 Rivertop Renewables, Inc. Improved nitric acid oxidation processes
EP2970955B1 (en) 2013-03-14 2018-11-14 Translate Bio, Inc. Methods for purification of messenger rna
CA2906281A1 (en) 2013-03-15 2014-09-18 Glaxosmithkline Biologicals Sa Rna purification methods
EP2971165A4 (en) * 2013-03-15 2016-11-23 Moderna Therapeutics Inc DISSOLUTION OF DNA FRAGMENTS IN MRNA MANUFACTURING METHODS
JP2016532100A (ja) 2013-07-05 2016-10-13 ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーLaboratoire Francais Du Fractionnement Et Des Biotechnologies アフィニティークロマトグラフィーマトリックス
KR20160133489A (ko) * 2014-03-07 2016-11-22 에이전시 포 사이언스, 테크놀로지 앤드 리서치 생물학적 생성물들의 제조를 위한 장치 및 방법들
EP4335539A3 (en) 2014-03-29 2024-05-01 Princeton Trade and Technology Inc. Blood processing cartridges and systems, and methods for extracorporeal blood therapies
WO2015164511A1 (en) * 2014-04-23 2015-10-29 Oleg Shinkazh High efficiency continuous countercurrent tangential chromatography
ES2750661T3 (es) * 2014-04-25 2020-03-26 Translate Bio Inc Métodos para la purificación de ARN mensajero
EA037972B1 (ru) * 2014-05-13 2021-06-17 Эмджен Инк. Системы и способы управления технологическим процессом для использования с фильтрами и в процессах фильтрации
DE102015108501A1 (de) * 2015-05-29 2016-12-01 Sartorius Stedim Biotech Gmbh Verfahren und Filtrationsvorrichtung zur Herstellung einer konzentrierten Produktlösung
US10426884B2 (en) 2015-06-26 2019-10-01 Novaflux Inc. Cartridges and systems for outside-in flow in membrane-based therapies
WO2017019944A1 (en) 2015-07-29 2017-02-02 Gradiant Corporation Osmotic desalination methods and associated systems
CN108260347A (zh) 2015-08-20 2018-07-06 通用电气健康护理生物科学股份公司 Cff/tff单次使用流路径中的再循环回路
EP3352888B8 (en) 2015-09-24 2022-01-12 Princeton Trade and Technology Inc. Cartridges for hollow fibre membrane-based therapies
CN108699253B (zh) * 2015-11-18 2022-01-25 阿瑞萨生物科技有限责任公司 用于制备细胞膜或病毒膜以及纳米颗粒的方法和***
US10463767B2 (en) 2016-04-22 2019-11-05 Vivex Biologics Group, Inc. Moldable bone composition
US11253629B2 (en) 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Bone gel sheet composition and method of manufacture
US9788950B1 (en) 2016-04-22 2017-10-17 Vivex Biomedical, Inc. Cohesive bone composition
US10596298B2 (en) 2016-04-22 2020-03-24 Vivex Biologics Group, Inc. Malleable demineralized bone composition and method of manufacture
US11253630B2 (en) 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Malleable demineralized bone composition and method of manufacture
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
CA3109230A1 (en) 2018-08-22 2020-02-27 Gradiant Corporation Liquid solution concentration system comprising isolated subsystem and related methods
CN112930396B (zh) 2018-08-24 2024-05-24 川斯勒佰尔公司 用于纯化信使rna的方法
US20220074831A1 (en) * 2019-01-25 2022-03-10 Becton Dickinson And Company Methods and apparatus to selectively extract constituents from biological samples
ES1256540Y (es) * 2020-07-30 2021-02-10 Euromed S A Composicion alimenticia en polvo que comprende eriocitrina
WO2022108891A1 (en) 2020-11-17 2022-05-27 Gradiant Corporaton Osmotic methods and systems involving energy recovery
KR20230108301A (ko) 2020-11-23 2023-07-18 아벡, 아이엔씨. 여과 시스템, 구성요소 및 방법
US20240043826A1 (en) 2022-07-29 2024-02-08 Sanofi Methods for ethanol-free mrna purification

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3744642A (en) * 1970-12-30 1973-07-10 Westinghouse Electric Corp Interface condensation desalination membranes
SE396017B (sv) * 1974-12-23 1977-09-05 Alfa Laval Ab Filtreringsforfarande, serskilt for ultrafiltrering
FR2380052A1 (fr) * 1977-02-11 1978-09-08 Akzo Nv Membrane de dialyse pour l'hemodialyse
US4191182A (en) * 1977-09-23 1980-03-04 Hemotherapy Inc. Method and apparatus for continuous plasmaphersis
JPS5681521A (en) * 1979-12-10 1981-07-03 Toyo Soda Mfg Co Ltd Separation of blood serum and protein
US4350156A (en) * 1980-05-29 1982-09-21 Japan Foundation For Artificial Organs Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid
US4746436A (en) * 1981-06-25 1988-05-24 Baxter Travenol Laboratories, Inc. Membrane plasmapheresis apparatus and process which utilize a flexible wall to variably restrict the flow of plasma filtrate and thereby stabilize transmembrane pressure
NO158658C (no) * 1981-07-01 1988-10-19 Pfizer Fremgangsmaate for konsentrering av vandige pseudoplastiske loesninger.
US4420398A (en) * 1981-08-13 1983-12-13 American National Red Cross Filteration method for cell produced antiviral substances
US4435289A (en) * 1981-12-23 1984-03-06 Romicon, Inc. Series ultrafiltration with pressurized permeate
EP0112510A1 (fr) * 1982-11-30 1984-07-04 "Continental Belro" Procédé et dispositif pour régler la concentration de matières déterminées dans un liquide
DE3485871T2 (de) * 1983-03-10 1993-01-21 Cpc Eng Corp Verfahren zur erhoehung der durchflussgeschwindigkeit von querstromfiltrationsanlagen.
JPS6135803A (ja) * 1984-07-26 1986-02-20 Shin Etsu Chem Co Ltd 複合中空糸
US4879040A (en) * 1984-11-15 1989-11-07 Baxter International Inc. Adaptive filter concentrate flow control system and method
US4874516A (en) * 1984-12-29 1989-10-17 Ngk Insulators, Ltd. A ceramic filter for semi-ultrafiltration
JPS61283305A (ja) * 1985-06-05 1986-12-13 Ube Ind Ltd 多孔質中空糸膜
JPS621404A (ja) * 1985-06-27 1987-01-07 Mitsubishi Rayon Co Ltd 多層複合中空繊維状膜及びその製造法
EP0227832B1 (en) * 1985-06-27 1990-09-19 Mitsubishi Rayon Co., Ltd. Composite hollow yarn and a process for producing the same
GB8600582D0 (en) * 1986-01-10 1986-02-19 Ca Minister Nat Defence Purifying biological materials
US4789482A (en) * 1986-02-10 1988-12-06 Millipore Corporation Method for separating liquid compositions on the basis of molecular weight
US4828705A (en) * 1986-10-31 1989-05-09 Kingston Technologies, Inc. Pressure-dependent anisotropic-transport membrane system
US4789489A (en) * 1988-02-26 1988-12-06 Buckman Laboratories International, Inc. Method for the control of mollusks
GB8812217D0 (en) * 1988-05-24 1988-06-29 Alcan Int Ltd Composite membranes
DE68928924T2 (de) * 1988-05-27 1999-07-01 Ngk Insulators Ltd Verfahren zur Herstellung einer porösen anorganischen Kompositmembran
US5256294A (en) * 1990-09-17 1993-10-26 Genentech, Inc. Tangential flow filtration process and apparatus

Also Published As

Publication number Publication date
DE69107855T2 (de) 1995-09-07
JP3828143B2 (ja) 2006-10-04
US5256294A (en) 1993-10-26
EP0552192B1 (en) 1995-03-01
US5490937A (en) 1996-02-13
CA2089663A1 (en) 1992-03-18
LV11283A (lv) 1996-06-20
ES2072017T3 (es) 1995-07-01
JPH06500730A (ja) 1994-01-27
WO1992004970A1 (en) 1992-04-02
ATE119063T1 (de) 1995-03-15
EP0552192A1 (en) 1993-07-28
LV11283B (en) 1996-12-20
DE69107855D1 (de) 1995-04-06
CA2089663C (en) 2002-05-28
JP2003334425A (ja) 2003-11-25

Similar Documents

Publication Publication Date Title
DK0552192T3 (da) Forbedret tangentialstrømningsfiltreringsfremgangsmåde og -apparat
DE3852037D1 (de) Verfahren zur trennung von teilchen nach grösse.
ATE171641T1 (de) Verfahren und apparat zur wassergewinnung aus einem vorfluter
JPS53108882A (en) Back washing method for hollow filament membrane
DE3884352D1 (de) Pervaporationsverfahren zur Trennung von Alkoholen von Äthern.
NZ332916A (en) Purification of biologically active peptides from milk
DK0553319T3 (da) Fremgangsmåde til adskillelse af en plastblanding bestående af mindst tre komponenter under anvendelse af elektrostatiske teknikker
DE69106815D1 (de) Verfahren zur Herstellung von veränderten Kohlenstoffmolekularsieben zur Gastrennung.
ATE18776T1 (de) Verfahren und vorrichtung zur zuechtung von mikroorganismen.
AU4685889A (en) Process for separating organometallic compounds and/or metal carbonyls from their solutions in organic media
DE59006656D1 (de) Verfahren zur Trennung und Rückgewinnung von Komponenten von Gemischen mittels Pervaporation.
DK0418517T3 (da) Skillemembran og skillefremgangsmåde
DE59107901D1 (de) Verfahren zur herstellung gereinigter glycolipide durch membrantrennverfahren
JPS56110625A (en) Separating method of blood plasma and apparatus for the same
DE68905403D1 (de) Verfahren zur erniedrigung des truebungspunktes von materialien unter anwendung eines ultrafiltrations-separationsprozesses.
ATE90662T1 (de) Verfahren zur trennung eines gemisches aus 1methoxypropanol-2 und wasser in seine bestandteile.
EP0489602A3 (en) Filtration arrangement
ATE32436T1 (de) Verfahren zur fraktionierten auftrennung von proteingemischen mittels membranen.
DE59004325D1 (de) Verfahren zur Abtrennung von Wasser aus einem Wasser, CO2 und Amine enthaltenden Gemisch.
ATE48014T1 (de) Vorrichtung zur abtrennung von produkten aus einem produkt-substrat-gemisch.
DE3882154D1 (de) Verfahren zur herstellung des pres 1/s2/s-hepatitis-b-antigens aus hefe.
JPS5411322A (en) Hollow cellulose fibers and their production
CA2064740A1 (en) Method for Enrichment of Oxygen 18 with a Laser
ATE25586T1 (de) Vorrichtung zur behandlung von blut und verfahren zur bluttrennung zur plasmagewinnung.
ATA54782A (de) Verfahren zur herstellung eines adsorbens aus verfahren zur herstellung eines adsorbens aus mordenit enthaltendem rhiolittuff zur trennung mordenit enthaltendem rhiolittuff zur trennung von sauerstoff und stickstoff enthaltenden von sauerstoff und stickstoff enthaltenden gasgemischen gasgemischen