DE3852037D1 - Verfahren zur trennung von teilchen nach grösse. - Google Patents

Verfahren zur trennung von teilchen nach grösse.

Info

Publication number
DE3852037D1
DE3852037D1 DE3852037T DE3852037T DE3852037D1 DE 3852037 D1 DE3852037 D1 DE 3852037D1 DE 3852037 T DE3852037 T DE 3852037T DE 3852037 T DE3852037 T DE 3852037T DE 3852037 D1 DE3852037 D1 DE 3852037D1
Authority
DE
Germany
Prior art keywords
particles
size
tangential flow
separating particles
liposomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3852037T
Other languages
English (en)
Other versions
DE3852037T2 (de
Inventor
Robert Lenk
Anthony Durning
Robert Klimchak
Joel Portnoff
Michelle Tomsho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26761847&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3852037(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of DE3852037D1 publication Critical patent/DE3852037D1/de
Publication of DE3852037T2 publication Critical patent/DE3852037T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B2227/00—Photographic printing apparatus
    • G03B2227/32—Projection printing apparatus, e.g. enlarging apparatus, copying camera
    • G03B2227/325—Microcapsule copiers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE3852037T 1987-07-29 1988-07-28 Verfahren zur trennung von teilchen nach grösse. Expired - Lifetime DE3852037T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7930987A 1987-07-29 1987-07-29
US16458088A 1988-03-07 1988-03-07
PCT/US1988/002598 WO1989000846A1 (en) 1987-07-29 1988-07-28 Method for size separation of particles

Publications (2)

Publication Number Publication Date
DE3852037D1 true DE3852037D1 (de) 1994-12-08
DE3852037T2 DE3852037T2 (de) 1995-03-23

Family

ID=26761847

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3852037T Expired - Lifetime DE3852037T2 (de) 1987-07-29 1988-07-28 Verfahren zur trennung von teilchen nach grösse.

Country Status (5)

Country Link
EP (1) EP0394265B1 (de)
JP (1) JP2877160B2 (de)
AT (1) ATE113468T1 (de)
DE (1) DE3852037T2 (de)
WO (1) WO1989000846A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
US5958449A (en) * 1992-12-02 1999-09-28 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for bacterial infections
AU3244393A (en) * 1992-12-02 1994-06-22 Vestar, Inc. Antibiotic formulation and process
US5759571A (en) * 1993-05-11 1998-06-02 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for drug resistant infections
ES2154680T3 (es) 1993-07-08 2001-04-16 Liposome Co Inc Metodo para controlar el tamaño de los liposomas.
IL115849A0 (en) * 1994-11-03 1996-01-31 Merz & Co Gmbh & Co Tangential filtration preparation of liposomal drugs and liposome product thereof
NZ503513A (en) 1997-09-18 2004-12-24 Skyepharma Inc Sustained-release liposomal anesthetic compositions
WO1999025319A1 (en) * 1997-11-14 1999-05-27 Depotech Corporation Production of multivesicular liposomes
US6165997A (en) * 1997-11-20 2000-12-26 Statens Serum Institut Phospholipids having antimicrobial activity with or without the presence of antimicrobials
FR2788780B1 (fr) * 1999-01-27 2001-03-30 Ap Cells Inc Procede de preparation de vesicules membranaires
CN101229098B (zh) * 2002-09-11 2012-02-29 田边三菱制药株式会社 微球的制备方法及相关的装置
US8182590B2 (en) * 2005-04-29 2012-05-22 University Of Rochester Ultrathin porous nanoscale membranes, methods of making, and uses thereof
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
WO2010005721A2 (en) 2008-06-16 2010-01-14 Bind Biosciences, Inc. Drug loaded polymeric nanoparticles and methods of making and using same
ES2721850T3 (es) 2008-06-16 2019-08-05 Pfizer Nanopartículas poliméricas terapéuticas que comprenden alcaloides vinca y procedimientos de fabricación y uso de las mismas
US8613951B2 (en) 2008-06-16 2013-12-24 Bind Therapeutics, Inc. Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
ES2776126T3 (es) 2008-12-15 2020-07-29 Pfizer Nanopartículas de circulación prolongada para la liberación sostenida de agentes terapéuticos
GB0917003D0 (en) * 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
JP5891175B2 (ja) 2009-12-11 2016-03-22 バインド セラピューティックス インコーポレイテッド 治療用粒子の凍結乾燥に対する安定製剤
ES2780156T3 (es) 2009-12-15 2020-08-24 Pfizer Composiciones terapéuticas de nanopartículas poliméricas con alta temperatura de transición vítrea o copolímeros de alto peso molecular
EP2402075A1 (de) 2010-06-28 2012-01-04 Bühler AG Verfahren und Vorrichtung zur Herstellung von Vesikeln
JP2015530387A (ja) 2012-09-04 2015-10-15 エライゾン ファーマシューティカルズ， エルエルシー 脂質複合体化シスプラチンによる肺癌の再発防止
CN104812381B (zh) 2012-09-17 2018-01-26 辉瑞大药厂 用于制备治疗性纳米颗粒的方法
ME03435B (de) 2014-03-14 2020-01-20 Pfizer Therapeutische nanopartikel mit einem behandlungsmittel sowie verfahren zur herstellung und verwendung davon
PL3142643T3 (pl) 2014-05-15 2019-12-31 Insmed Incorporated Sposoby leczenia zakażeń płuc prątkami niegruźliczymi
CN114146063A (zh) * 2014-07-02 2022-03-08 川斯勒佰尔公司 信使rna的包封
EP3773505A4 (de) * 2018-03-30 2021-12-22 Insmed Incorporated Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032578B1 (de) * 1980-01-16 1984-07-25 Hans Georg Prof. Dr. Weder Verfahren und Dialysiereinrichtung zur Herstellung von Bilayer-Vesikeln und Verwendung der Bilayer-Vesikel
US4420398A (en) * 1981-08-13 1983-12-13 American National Red Cross Filteration method for cell produced antiviral substances
US4888115A (en) * 1983-12-29 1989-12-19 Cuno, Incorporated Cross-flow filtration
DE3432718C1 (de) * 1984-09-06 1986-05-22 Biotest Pharma GmbH, 6000 Frankfurt Verfahren zur Herstellung einer Loesung von Milch- und/oder Kolostralimmunglobulinen
FR2576805B1 (fr) * 1985-02-01 1989-08-25 Lyonnaise Eaux Appareil de filtration tangentielle
GB2176715A (en) * 1985-06-27 1987-01-07 Apv Int Ltd Beer filtration
IL79985A0 (en) * 1985-09-13 1986-12-31 Ausimont Spa Purification of oils containing solid matter in suspension

Also Published As

Publication number Publication date
JP2877160B2 (ja) 1999-03-31
EP0394265A4 (en) 1991-07-31
DE3852037T2 (de) 1995-03-23
WO1989000846A1 (en) 1989-02-09
JPH02504362A (ja) 1990-12-13
EP0394265A1 (de) 1990-10-31
ATE113468T1 (de) 1994-11-15
EP0394265B1 (de) 1994-11-02

Similar Documents

Publication Publication Date Title
DE3852037D1 (de) Verfahren zur trennung von teilchen nach grösse.
DE69107855D1 (de) Verbessertes verfahren und vorrichtung zur tangentiellen filtrierung.
DE69132172D1 (de) Verfahren zur Abtrennung von Blutkomponenten aus Vollblut
ATE48086T1 (de) Verfahren und vorrichtung zur selektiven extrakorporalen abtrennung pathologischer und/oder toxischer blutbestandteile.
DE68911412D1 (de) Verfahren zur Gas-Flüssig-Trennung und Filtration.
DE69107115D1 (de) Verfahren und Apparat zur Adsorptionsreinigung von zu destillierender Luft.
DE69129419D1 (de) Gerät und Verfahren zur Trennung von Blutbestandteilen aus Vollblut
DE69019690D1 (de) Verfahren zur Filtrierung und Reinigung von Wasser.
ATE160294T1 (de) Verfahren und vorrichtung zum entfernen von dna und viren
DE69106100D1 (de) Verfahren zur Trennung durch Adsorption und Adsorber.
DE69311060D1 (de) Vorrichtung und Verfahren zur Durchführung der Phasentrennung durch Filtration und Zentrifugation
ATE70366T1 (de) Magnetische teilchen zur verwendung in trennungen.
DE69110392D1 (de) Verfahren zur abtrennung von verunreinigungen aus wässrigen lösungen von rohethanol.
DE69213309D1 (de) Vorrichtung zur Trennung und Zurückgewinnung von Gasen
DE59006656D1 (de) Verfahren zur Trennung und Rückgewinnung von Komponenten von Gemischen mittels Pervaporation.
AT383963B (de) Filter zur abtrennung von gasfoermigen oder fluessigen komponenten aus fluiden und verfahren zu dessen herstellung
DE69031481D1 (de) Verfahren zur Gewinnung von Ginkgoliden aus Ginkgoblättern und ihre Reinigung
ATE154033T1 (de) Verfahren zur reinigung von proteinen
GB2110112A (en) Method and apparatus for high-efficiency ultrafiltration of complex fluids
AT377709B (de) Filterapparat zur abtrennung von feststoffen aus fluessigkeiten
DE68911158D1 (de) Verfahren zur Abtrennung und Gewinnung von Erythrit aus einem dieses enthaltenden Kulturmedium.
DE69010083D1 (de) Kontinuierliches Verfahren zur Trennung von teils in wasserlöslichen Bestandteilen aus einem Schlamm.
DE3465022D1 (en) Apparatus for gas-liquid separation and its use in the elimination of oil from bearing-casing air in turbo machinery
NO914955D0 (no) Fremgangsmaate for fremstilling av hvitt fosfor
ATE78177T1 (de) Verfahren zur extrakorporalen behandlung von ascites-fluessigkeit.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: ELAN PHARMACEUTICALS,INC.(N.D.GES.D.STAATES DE, US