DK0473671T3 - Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel - Google Patents

Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel

Info

Publication number
DK0473671T3
DK0473671T3 DK90908385.9T DK90908385T DK0473671T3 DK 0473671 T3 DK0473671 T3 DK 0473671T3 DK 90908385 T DK90908385 T DK 90908385T DK 0473671 T3 DK0473671 T3 DK 0473671T3
Authority
DK
Denmark
Prior art keywords
prepare
sigma receptor
receptor ligands
anxiolytic agent
anxiolytic
Prior art date
Application number
DK90908385.9T
Other languages
Danish (da)
English (en)
Inventor
Eckard Weber
John F W Keana
Original Assignee
Oregon State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon State filed Critical Oregon State
Application granted granted Critical
Publication of DK0473671T3 publication Critical patent/DK0473671T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK90908385.9T 1989-05-02 1990-05-02 Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel DK0473671T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34649489A 1989-05-02 1989-05-02

Publications (1)

Publication Number Publication Date
DK0473671T3 true DK0473671T3 (da) 1994-09-19

Family

ID=23359655

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90908385.9T DK0473671T3 (da) 1989-05-02 1990-05-02 Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel

Country Status (9)

Country Link
EP (1) EP0473671B1 (fr)
JP (1) JPH05500798A (fr)
AT (1) ATE110265T1 (fr)
AU (1) AU642881B2 (fr)
CA (1) CA2054211A1 (fr)
DE (1) DE69011859T2 (fr)
DK (1) DK0473671T3 (fr)
ES (1) ES2057568T3 (fr)
WO (1) WO1990014067A2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5502255A (en) * 1986-07-10 1996-03-26 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Substituted guanidines having high binding to the sigma receptor and the use thereof
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
ZA911553B (en) 1990-03-02 1991-12-24 Oregon State Tri-and tetra-substituted guanidines and their use as excitatory amino acid and antagonists
WO1991018868A1 (fr) * 1990-05-25 1991-12-12 STATE OF OREGON, acting by and through the OREGON STATE BOARD OF HIGHER EDUCATION, acting for and onbehalf of the OREGON HEALTH SCIENCES UNIVERSITY Guanidines substituees ayant un coefficient de liaison eleve avec le recepteur sigma et utilisation de ces substances
EP0940139B1 (fr) * 1991-02-08 2005-02-02 Scion Pharmaceuticals, Inc. Guanidines substituées et leurs dérivés utilisés comme modulateurs de libération de neurotransmetteurs et nouveau procédé d'identification d'inhibiteurs de libération de neurotransmetteurs
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
CN1188121C (zh) * 1993-05-27 2005-02-09 剑桥神经科学公司 治疗性取代的胍类
WO1995014467A1 (fr) * 1993-11-22 1995-06-01 Cambridge Neuroscience, Inc. Guanidines therapeutiques
EP0739200A4 (fr) * 1993-11-23 1997-12-17 Cambridge Neuroscience Inc Guanidines substituees a usage therapeutique
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
EP0751767A4 (fr) 1994-02-03 1997-12-10 Cambridge Neuroscience Inc Guanidines therapeutiques
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
WO1995023132A1 (fr) * 1994-02-23 1995-08-31 Cambridge Neuroscience, Inc. Agents bloquants des canaux ioniques et leur procedes d'utilisation
US6875759B1 (en) 1999-07-21 2005-04-05 Kadmus Pharmaceuticals Substituted guanidines and the use thereof
EP1749824A1 (fr) 2005-08-03 2007-02-07 Neuro3D Derivés de la benzodiazepine, préparation et utlisations thérapeutiques
WO2007022964A2 (fr) 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Composes guanidine a substitution hetaryl et utilisation en tant que partenaires de liaison pour des recepteurs de 5-ht5
EP2377530A3 (fr) 2005-10-21 2012-06-20 Braincells, Inc. Modulation de neurogénèse par inhibition PDE
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2377531A2 (fr) 2006-05-09 2011-10-19 Braincells, Inc. Neurogénèse par modulation de l'angiotensine
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (fr) 2009-02-25 2010-09-02 Braincells, Inc. Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine
AU2013292519B2 (en) * 2012-07-19 2017-12-07 Drexel University Sigma receptor ligands for modulating cellular protein homeostasis
US11117870B2 (en) 2017-11-01 2021-09-14 Drexel University Compounds, compositions, and methods for treating diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709094A (en) * 1986-07-10 1987-11-24 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Sigma brain receptor ligands and their use

Also Published As

Publication number Publication date
EP0473671A4 (en) 1992-04-01
DE69011859T2 (de) 1994-12-15
ES2057568T3 (es) 1994-10-16
DE69011859D1 (de) 1994-09-29
WO1990014067A2 (fr) 1990-11-29
CA2054211A1 (fr) 1990-11-03
AU642881B2 (en) 1993-11-04
ATE110265T1 (de) 1994-09-15
AU5728790A (en) 1990-12-18
EP0473671A1 (fr) 1992-03-11
WO1990014067A3 (fr) 1991-04-04
EP0473671B1 (fr) 1994-08-24
JPH05500798A (ja) 1993-02-18

Similar Documents

Publication Publication Date Title
DK0473671T3 (da) Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel
ATE174330T1 (de) Herbizide, substituierte aryl-haloalkylpyrazole
BR0012243A (pt) Triflúor butenos nematocidas
DK0428038T3 (da) Transdermal administration af 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol
NO952494L (no) Nytt protein fra urin med betegnelse komponent B
ES521422A0 (es) Procedimiento para la obtencion de derivados de carboxilamida n-glicosilados.
DK0415613T3 (da) Anvendelse af sertralin til behandling af præmatur ejakulation
ES2059121T5 (es) Uso de agentes sensibilizantes de la insulina para tratar la hipertension.
LV11894A (lv) Jauni hromana un tiohromana atvasinajumi
FI904851A0 (fi) Radiomaerkta antikoagulantpeptider.
DK261490D0 (da) New pharmaceutical compound
FI972703A (fi) Rekombinantti IL-5-antagonisteja, jotka ovat käyttökelpoisia hoidettaessa IL-5:een liittyviä sairauksia
DE69831409D1 (de) Chalcon-derivate mit antiproliferativer aktivität
DK455088D0 (da) Syntetiske receptoranaloger
DK0471718T3 (da) Paracetamolholdigt farmaceutisk præparat
ES2078289T3 (es) Agente para mejorar la recuperacion de anexinas.
DK0571457T3 (da) Iloprost med virkning overfor cerebral malaria.
SE8700156L (sv) Kosmetiska kompositioner med hudlugnande och hudgenerande effekt och forfarande for framstellning derav
ATE130304T1 (de) Neue alpha-glukosidaseinhibitoren.
EP0116628A4 (fr) 1-acyl-3-pyridylmethylguanidines et leur utilisation comme agents anti-hypertensifs.
DE68913995D1 (de) Zusammensetzung zur behandlung progressiver myopie.
ES2096559T3 (es) Interferon gamma humano, procedimiento para la preparacion de dicho interferon gamma humano, y su uso.
ES2051953T3 (es) Derivados isomeros de trimetilbiciclo(4,3,0)nonano.
DK134982A (da) Fremgangsmaade til fremstilling af guanidinopyrimidiner
SE9501773D0 (sv) New use