DE69942317D1 - Schmerzlinderung mit anandamide - Google Patents

Schmerzlinderung mit anandamide

Info

Publication number
DE69942317D1
DE69942317D1 DE69942317T DE69942317T DE69942317D1 DE 69942317 D1 DE69942317 D1 DE 69942317D1 DE 69942317 T DE69942317 T DE 69942317T DE 69942317 T DE69942317 T DE 69942317T DE 69942317 D1 DE69942317 D1 DE 69942317D1
Authority
DE
Germany
Prior art keywords
anandamide
pain relief
pain
relief
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942317T
Other languages
English (en)
Inventor
Antonio Calignano
Rana Giovanna La
Andrea Giuffrida
Daniele Piomelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurosciences Research Foundation Inc
Original Assignee
Neurosciences Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosciences Research Foundation Inc filed Critical Neurosciences Research Foundation Inc
Application granted granted Critical
Publication of DE69942317D1 publication Critical patent/DE69942317D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69942317T 1998-05-29 1999-05-28 Schmerzlinderung mit anandamide Expired - Lifetime DE69942317D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8728998P 1998-05-29 1998-05-29

Publications (1)

Publication Number Publication Date
DE69942317D1 true DE69942317D1 (de) 2010-06-10

Family

ID=22204284

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69942317T Expired - Lifetime DE69942317D1 (de) 1998-05-29 1999-05-28 Schmerzlinderung mit anandamide
DE69927496T Expired - Lifetime DE69927496T2 (de) 1998-05-29 1999-05-28 Schmerzlinderung mit endogenen cannabinoiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69927496T Expired - Lifetime DE69927496T2 (de) 1998-05-29 1999-05-28 Schmerzlinderung mit endogenen cannabinoiden

Country Status (7)

Country Link
US (2) US6348498B1 (de)
EP (1) EP1082292B1 (de)
JP (1) JP4817495B2 (de)
AU (1) AU776414B2 (de)
CA (1) CA2330681C (de)
DE (2) DE69942317D1 (de)
WO (1) WO1999060987A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI242015B (en) 1999-11-29 2005-10-21 Akzo Nobel Nv 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
CA2410401A1 (en) 2000-05-23 2001-11-29 Daniele Piomelli A novel treatment for cough
US20050054730A1 (en) * 2001-03-27 2005-03-10 The Regents Of The University Of California Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha
US6911474B2 (en) 2001-03-27 2005-06-28 The Regents Of The University Of California Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism
TW200407110A (en) * 2001-11-23 2004-05-16 Astrazeneca Ab New use for the treatment of gastroesophageal reflux disease
US7351729B2 (en) 2002-03-08 2008-04-01 Signal Pharmaceuticals, Llc JNK inhibitors for use in combination therapy for treating or managing proliferative disorders and cancers
US6825209B2 (en) 2002-04-15 2004-11-30 Research Triangle Institute Compounds having unique CB1 receptor binding selectivity and methods for their production and use
US7765162B2 (en) * 2002-10-07 2010-07-27 Mastercard International Incorporated Method and system for conducting off-line and on-line pre-authorized payment transactions
US20070129441A1 (en) * 2003-05-06 2007-06-07 University Of North Texas Health Science Center At Fort Worth Protection of cells from adverse external or intrinsic effects, cellular degeneration and death by n-acylethanolamines
US20060142395A1 (en) * 2003-05-06 2006-06-29 University Of North Texas Health Science Center Modulation of intracellular calcium signaling by N-acylethanolamines
WO2005046580A2 (en) * 2003-10-16 2005-05-26 The Regents Of The University Of California Dietary and other compositions, compounds, and methods for reducing body fat, controlling appetite, and modulating fatty acid metabolism
GB0403629D0 (en) * 2004-02-19 2004-03-24 Imp College Innovations Ltd Methods
WO2006116773A2 (en) * 2005-04-28 2006-11-02 The Regents Of The University Of California Methods, compositions, and compounds for modulation of monoacylglycerol lipase, pain, and stress-related disorders
US20090029984A1 (en) * 2005-07-11 2009-01-29 N.V. Organon Synergistic combination for the treatment of pain (cannabinoid receptor agonist and opioid receptor agonist)
US20070060638A1 (en) * 2005-08-26 2007-03-15 Olmstead Mary C Methods and therapies for potentiating therapeutic activities of a cannabinoid receptor agonist via administration of a cannabinoid receptor antagonist
JP4994295B2 (ja) * 2007-04-20 2012-08-08 田辺三菱製薬株式会社 医薬組成物
WO2009133574A1 (en) * 2008-04-28 2009-11-05 Vermont Italia Srl Pharmaceutical formulation containing palmitoyl ethanolamide and stearoyl ethanolamide
WO2010013240A1 (en) 2008-07-31 2010-02-04 Dekel Pharmaceuticals Ltd. Compositions and methods for treating inflammatory disorders
ITPD20090360A1 (it) * 2009-12-01 2011-06-02 Vermont Italia Srl Composizione per uso topico
WO2012015704A2 (en) 2010-07-28 2012-02-02 The Regents Of The University Of California Peripherally restricted faah inhibitors
ES2708723T3 (es) 2011-08-19 2019-04-10 Univ California Inhibidores de FAAH restringidos de forma periférica sustituidos en posición meta por bifenilo
CN104379735A (zh) 2012-04-13 2015-02-25 Reg生命科学有限责任公司 烷醇酰胺及酰胺胺的微生物生产及其用途
ES2498521B1 (es) * 2013-02-20 2015-08-18 Fundación Pública Andaluza Para La Investigación De Málaga En Biomedicina Y Salud (Fimabis) Formulaciones basadas en nanoemulsiones y su uso para el tratamiento de la obesidad
WO2015157313A1 (en) 2014-04-07 2015-10-15 The Regents Of The University Of California Inhibitors of fatty acid amide hydrolase (faah) enzyme with improved oral bioavailability and their use as medicaments
ES2935605T3 (es) * 2015-04-29 2023-03-08 Scisparc Ltd Combinaciones de cannabinoides y N-aciletanolaminas
WO2018011813A1 (en) 2016-07-14 2018-01-18 Therapix Biosciences Ltd. Compositions and methods of potentiating antimicrobials
US10278951B1 (en) 2016-09-29 2019-05-07 Jon Newland Method of treating opiate dependency using tetrahydrocannabinol extracts
SG10201807034XA (en) 2017-09-05 2019-04-29 Frimline Private Ltd A pharmaceutical composition for improving or preventing progression of Chronic Kidney Disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618955A (en) * 1992-11-30 1997-04-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Fatty acid derivatives and pharmaceutical compositions containing same
IT1271266B (it) * 1994-12-14 1997-05-27 Valle Francesco Della Impiego terapeutico di ammidi di acidi mono e bicarbossilici con amminoalcoli,selettivamente attive sul recettore periferico dei cannabinoidi
US5925972A (en) 1996-09-27 1999-07-20 Ngk Insulators, Ltd. Multiple element particle sensor and signal processing electronics

Also Published As

Publication number Publication date
EP1082292B1 (de) 2005-09-28
CA2330681A1 (en) 1999-12-02
WO1999060987A2 (en) 1999-12-02
US6656972B2 (en) 2003-12-02
WO1999060987A9 (en) 2000-09-08
US20020173550A1 (en) 2002-11-21
CA2330681C (en) 2008-08-26
JP2002516262A (ja) 2002-06-04
EP1082292A2 (de) 2001-03-14
WO1999060987A8 (en) 2000-07-27
WO1999060987A3 (en) 2000-01-27
AU776414B2 (en) 2004-09-09
JP4817495B2 (ja) 2011-11-16
AU4672999A (en) 1999-12-13
DE69927496D1 (de) 2006-02-09
EP1082292A4 (de) 2003-04-02
DE69927496T2 (de) 2006-07-06
US6348498B1 (en) 2002-02-19

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Legal Events

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