DE69915458D1 - Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen - Google Patents

Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen

Info

Publication number
DE69915458D1
DE69915458D1 DE69915458T DE69915458T DE69915458D1 DE 69915458 D1 DE69915458 D1 DE 69915458D1 DE 69915458 T DE69915458 T DE 69915458T DE 69915458 T DE69915458 T DE 69915458T DE 69915458 D1 DE69915458 D1 DE 69915458D1
Authority
DE
Germany
Prior art keywords
dextran
molecular weight
joint diseases
daltons
joint
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69915458T
Other languages
English (en)
Other versions
DE69915458T2 (de
Inventor
Ha Green
B Buckley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GLENPHARMA UPPSALA
Original Assignee
GLENPHARMA UPPSALA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GLENPHARMA UPPSALA filed Critical GLENPHARMA UPPSALA
Application granted granted Critical
Publication of DE69915458D1 publication Critical patent/DE69915458D1/de
Publication of DE69915458T2 publication Critical patent/DE69915458T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69915458T 1998-03-27 1999-03-25 Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen Expired - Lifetime DE69915458T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49055 1998-03-27
US09/049,055 US5902800A (en) 1998-03-27 1998-03-27 Dextran formulations and method for treatment of inflammatory joint disorders
PCT/IB1999/000525 WO1999049874A1 (en) 1998-03-27 1999-03-25 Dextran formulations and method for treatment of inflammatory joint disorders

Publications (2)

Publication Number Publication Date
DE69915458D1 true DE69915458D1 (de) 2004-04-15
DE69915458T2 DE69915458T2 (de) 2005-02-24

Family

ID=21957832

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915458T Expired - Lifetime DE69915458T2 (de) 1998-03-27 1999-03-25 Dextran formulierungen zur behandlung entzündlicher gelenkerkrankungen

Country Status (12)

Country Link
US (1) US5902800A (de)
EP (1) EP1066044B1 (de)
JP (1) JP4511031B2 (de)
AT (1) ATE261308T1 (de)
AU (1) AU753124B2 (de)
BR (1) BR9909199A (de)
CA (1) CA2326510C (de)
DE (1) DE69915458T2 (de)
DK (1) DK1066044T3 (de)
ES (1) ES2217741T3 (de)
MX (1) MXPA00009159A (de)
WO (1) WO1999049874A1 (de)

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DE19908441C1 (de) * 1999-02-26 2000-08-31 Chakravarty Adusumalli Injektionslösung zur Behandlung von Arthrosen
US6800298B1 (en) * 2000-05-11 2004-10-05 Clemson University Biological lubricant composition and method of applying lubricant composition
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
CA2525994C (en) 2002-06-24 2012-10-16 Tufts University Silk biomaterials and methods of use thereof
EP1613796B1 (de) 2003-04-10 2017-03-22 Tufts University Konzentrierte wässrige seidenfibroinlösung und deren verwendung
JP2008502739A (ja) 2004-06-11 2008-01-31 トラスティーズ オブ タフツ カレッジ 絹に基づく薬物送達システム
US20100028451A1 (en) 2006-09-26 2010-02-04 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
WO2008106485A2 (en) 2007-02-27 2008-09-04 Trustees Of Tufts College Tissue-engineered silk organs
CA2686093C (en) 2007-04-16 2018-05-08 Corium International, Inc. Solvent-cast microneedle arrays containing active
WO2009023615A1 (en) 2007-08-10 2009-02-19 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
EP2480075B1 (de) * 2009-09-23 2020-07-01 Glenpharma AB Zusammensetzungen und verfahren zur herbeiführung oder erweiterung einer bindegewebereparatur
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
WO2011160146A1 (en) 2010-06-23 2011-12-29 Croma-Pharma Gesellschaft M.B.H. Pharmaceutical preparation containing dextran and sodium hyaluronate for the treatment of joint disorders
GB201020300D0 (en) 2010-11-30 2011-01-12 Vitrolife Sweden Ab Product
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
CA2867464A1 (en) 2012-03-20 2013-09-26 Trustees Of Tufts College Silk reservoirs for drug delivery
EP2836236B1 (de) 2012-04-13 2019-01-02 Trustees Of Tufts College Verfahren und zusammensetzungen zur herstellung einer seidenmikrokugel
WO2014012101A1 (en) 2012-07-13 2014-01-16 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
RU2674083C2 (ru) 2013-03-12 2018-12-04 Кориум Интернэшнл, Инк. Аппликаторы с микровыступами
EP2970411B1 (de) 2013-03-15 2018-05-09 Trustees Of Tufts College Niedermolekulare seidenzusammensetzungen und stabilisierende seidenzusammensetzungen
WO2014150293A1 (en) * 2013-03-15 2014-09-25 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
WO2014176458A2 (en) 2013-04-24 2014-10-30 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
US10513720B2 (en) 2014-02-10 2019-12-24 Bio-E.R.G. S.R.L. Method for the production of dextran
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
US10758645B2 (en) 2014-12-17 2020-09-01 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CA2995233C (en) 2015-07-20 2024-01-02 Tufts University Biodegradable silk ear tubes
WO2017189832A1 (en) 2016-04-29 2017-11-02 Trustees Of Tufts College An artificial silk based innervated cornea
US11298443B2 (en) 2016-07-01 2022-04-12 Trustees Of Tufts College Innervated artificial skin
US11248313B2 (en) 2016-08-01 2022-02-15 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
US20200000713A1 (en) 2017-01-20 2020-01-02 Massachusetts Institute Of Technology Injectable polymer micro-depots for controlled local drug delivery
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2019094702A1 (en) 2017-11-10 2019-05-16 Cocoon Biotech Inc. Ocular applications of silk-based products
KR102075596B1 (ko) 2017-12-04 2020-02-10 이일훈 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
AU2020288624A1 (en) 2019-06-04 2022-02-03 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
KR102172290B1 (ko) * 2020-02-04 2020-10-30 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
KR102316719B1 (ko) * 2020-02-04 2021-10-25 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
KR102468374B1 (ko) * 2020-10-26 2022-11-17 메디슨파크 주식회사 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
DK110188D0 (da) * 1988-03-02 1988-03-02 Claus Selch Larsen High molecular weight prodrug derivatives of antiinflammatory drugs
JP2788340B2 (ja) * 1989-12-21 1998-08-20 株式会社ニッショー 炎症治療剤
WO1992013541A1 (de) * 1991-01-30 1992-08-20 Hoechst Aktiengesellschaft Die verwendung substituierter polysaccharide zur behandlung von degenerativen gelenkerkrankungen
CA2060223C (en) * 1991-02-12 1999-07-20 Clarence C. Lee Injectable medical lubricating fluid composition and method of use

Also Published As

Publication number Publication date
JP4511031B2 (ja) 2010-07-28
AU2848299A (en) 1999-10-18
EP1066044B1 (de) 2004-03-10
CA2326510A1 (en) 1999-10-07
MXPA00009159A (es) 2004-11-22
EP1066044A1 (de) 2001-01-10
DE69915458T2 (de) 2005-02-24
WO1999049874A1 (en) 1999-10-07
BR9909199A (pt) 2000-12-05
US5902800A (en) 1999-05-11
ATE261308T1 (de) 2004-03-15
DK1066044T3 (da) 2004-07-12
JP2002509890A (ja) 2002-04-02
ES2217741T3 (es) 2004-11-01
CA2326510C (en) 2007-06-12
AU753124B2 (en) 2002-10-10

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