DE69911975D1 - In-vitro stimulation von beta zellen vermehrung - Google Patents

In-vitro stimulation von beta zellen vermehrung

Info

Publication number
DE69911975D1
DE69911975D1 DE69911975T DE69911975T DE69911975D1 DE 69911975 D1 DE69911975 D1 DE 69911975D1 DE 69911975 T DE69911975 T DE 69911975T DE 69911975 T DE69911975 T DE 69911975T DE 69911975 D1 DE69911975 D1 DE 69911975D1
Authority
DE
Germany
Prior art keywords
diabetes
type
beta cell
relates
vitro stimulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69911975T
Other languages
English (en)
Other versions
DE69911975T2 (de
Inventor
H Iriis Nielsen
Nissen Friedrichsen
Susanne Rugh
Niels Tromholt
Soren Bjorn
Bjerre Knudsen
Jeppe Sturis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26065042&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69911975(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE69911975D1 publication Critical patent/DE69911975D1/de
Application granted granted Critical
Publication of DE69911975T2 publication Critical patent/DE69911975T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/335—Glucagon; Glucagon-like peptide [GLP]; Exendin
DE69911975T 1998-07-31 1999-07-29 In-vitro stimulation von beta zellen vermehrung Expired - Lifetime DE69911975T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA199800998 1998-07-31
DK99898 1998-07-31
DKPA199801025 1998-08-12
DK102598 1998-08-12
PCT/DK1999/000424 WO2000007617A1 (en) 1998-07-31 1999-07-29 Use of glp-1 and analogues for preventing type ii diabetes

Publications (2)

Publication Number Publication Date
DE69911975D1 true DE69911975D1 (de) 2003-11-13
DE69911975T2 DE69911975T2 (de) 2004-09-09

Family

ID=26065042

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69911975T Expired - Lifetime DE69911975T2 (de) 1998-07-31 1999-07-29 In-vitro stimulation von beta zellen vermehrung

Country Status (7)

Country Link
US (2) US20030224983A1 (de)
EP (3) EP1100530B1 (de)
JP (1) JP2002523333A (de)
AT (1) ATE251465T1 (de)
AU (1) AU5027299A (de)
DE (1) DE69911975T2 (de)
WO (1) WO2000007617A1 (de)

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AU5027299A (en) 2000-02-28
JP2002523333A (ja) 2002-07-30
EP1932535A3 (de) 2008-10-29
WO2000007617A1 (en) 2000-02-17
US20030224983A1 (en) 2003-12-04
DE69911975T2 (de) 2004-09-09
US20070203068A1 (en) 2007-08-30
EP1100530B1 (de) 2003-10-08
EP1100530A1 (de) 2001-05-23
EP1932535A2 (de) 2008-06-18
ATE251465T1 (de) 2003-10-15
EP1306091A3 (de) 2003-05-21

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