DE69842166D1 - Zusammensetzung und verfahren zur regulierung der adhäsion von zellen und biomolekülen an hydrophobe oberflächen - Google Patents
Zusammensetzung und verfahren zur regulierung der adhäsion von zellen und biomolekülen an hydrophobe oberflächenInfo
- Publication number
- DE69842166D1 DE69842166D1 DE69842166T DE69842166T DE69842166D1 DE 69842166 D1 DE69842166 D1 DE 69842166D1 DE 69842166 T DE69842166 T DE 69842166T DE 69842166 T DE69842166 T DE 69842166T DE 69842166 D1 DE69842166 D1 DE 69842166D1
- Authority
- DE
- Germany
- Prior art keywords
- composition
- adhesion
- biomolecules
- regulating
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/02—Compounds containing any of the groups, e.g. carbazates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/823—Immunogenic carrier or carrier per se
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/815—Carrier is a synthetic polymer
- Y10S530/816—Attached to the carrier via a bridging agent
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/784,203 US6284503B1 (en) | 1993-08-20 | 1997-01-15 | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
PCT/US1998/000337 WO1998031734A1 (en) | 1997-01-15 | 1998-01-15 | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69842166D1 true DE69842166D1 (de) | 2011-04-21 |
Family
ID=25131669
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69842166T Expired - Lifetime DE69842166D1 (de) | 1997-01-15 | 1998-01-15 | Zusammensetzung und verfahren zur regulierung der adhäsion von zellen und biomolekülen an hydrophobe oberflächen |
Country Status (10)
Country | Link |
---|---|
US (3) | US6284503B1 (de) |
EP (1) | EP1002066B1 (de) |
JP (1) | JP2001512565A (de) |
KR (1) | KR20000070229A (de) |
AT (1) | ATE501249T1 (de) |
AU (1) | AU740877B2 (de) |
CA (1) | CA2277995C (de) |
DE (1) | DE69842166D1 (de) |
IL (2) | IL130961A0 (de) |
WO (1) | WO1998031734A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
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US6284503B1 (en) * | 1993-08-20 | 2001-09-04 | University Of Utah Research Foundation | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
JP2002515932A (ja) * | 1997-04-18 | 2002-05-28 | カリフォルニア インスティチュート オブ テクノロジー | 多機能性ポリマー性組織コーティング |
DE19748489A1 (de) * | 1997-11-03 | 1999-05-06 | Roche Diagnostics Gmbh | Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren |
AR021240A1 (es) * | 1998-11-13 | 2002-07-03 | Commw Scient Ind Res Org | Peptidos acoplados |
DE60041255D1 (de) * | 1999-04-28 | 2009-02-12 | Eidgenoess Tech Hochschule | Polyionische beschichtungen für analytische und sensor-vorrichtungen |
JP2001083162A (ja) * | 1999-09-17 | 2001-03-30 | Fuji Photo Film Co Ltd | 膜状生体高分子吸着材及び吸着用キット |
US7220276B1 (en) * | 2000-03-06 | 2007-05-22 | Surmodics, Inc. | Endovascular graft coatings |
US6706479B2 (en) * | 2000-10-05 | 2004-03-16 | Virginia Tech Intellectual Properties, Inc. | Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips |
AU2002211736A1 (en) * | 2000-10-13 | 2002-04-22 | University Of Cincinnati | Methods for synthesizing precipitated silica and use thereof |
DE10100961B4 (de) | 2001-01-11 | 2005-08-04 | Polyzenix Gmbh | Körperverträglicher Werkstoff und mit diesem Werkstoff beschichtetes Substrat für die Züchtung von Zellen und künstlichen aus Zellen aufgebauten oder gewachsenen organischen Implantaten |
US9080146B2 (en) | 2001-01-11 | 2015-07-14 | Celonova Biosciences, Inc. | Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface |
US7645721B2 (en) * | 2001-02-02 | 2010-01-12 | Richard Nagler | End group activated polymers with oligonucleotide ligands |
US20050244843A1 (en) * | 2001-11-16 | 2005-11-03 | Wen-Tien Chen | Blood test prototypes and methods for the detection of circulating tumor and endothelial cells |
US20030148017A1 (en) * | 2001-12-07 | 2003-08-07 | Olli Tuominen | Copolymer coating for a hydrophobic membrane |
IL158569A0 (en) * | 2002-06-29 | 2004-05-12 | Aquanova Ger Solubilisate Tech | Isoflavone concentrates and methods for the production thereof |
US7598224B2 (en) * | 2002-08-20 | 2009-10-06 | Biosurface Engineering Technologies, Inc. | Dual chain synthetic heparin-binding growth factor analogs |
US8227411B2 (en) * | 2002-08-20 | 2012-07-24 | BioSurface Engineering Technologies, Incle | FGF growth factor analogs |
US7166574B2 (en) | 2002-08-20 | 2007-01-23 | Biosurface Engineering Technologies, Inc. | Synthetic heparin-binding growth factor analogs |
US20050059140A1 (en) * | 2003-09-12 | 2005-03-17 | Andrea Liebmann-Vinson | Methods of surface modification to enhance cell adhesion |
DE10358565B4 (de) * | 2003-12-15 | 2007-06-28 | P.A.L.M. Microlaser Technologies Ag | Aufnahmeelement zum Aufnehmen eines aus einer biologischen Masse mittels Laserstrahlung herausgelösten Objekts und Verfahren zur Gewinnung und Verarbeitung eines biologischen Objekts |
US7414028B1 (en) * | 2004-02-04 | 2008-08-19 | Biosurface Engineering Technologies, Inc. | Growth factor analogs |
US7528105B1 (en) | 2004-02-10 | 2009-05-05 | Biosurface Engineering Technologies | Heterodimeric chain synthetic heparin-binding growth factor analogs |
US7671012B2 (en) | 2004-02-10 | 2010-03-02 | Biosurface Engineering Technologies, Inc. | Formulations and methods for delivery of growth factor analogs |
US20080227696A1 (en) * | 2005-02-22 | 2008-09-18 | Biosurface Engineering Technologies, Inc. | Single branch heparin-binding growth factor analogs |
US20060024347A1 (en) * | 2004-02-10 | 2006-02-02 | Biosurface Engineering Technologies, Inc. | Bioactive peptide coatings |
WO2005082005A2 (en) | 2004-02-20 | 2005-09-09 | Biosurface Engineering Technologies, Inc., Et Al. | Positive modulator of bone morphogenic protein-2 |
EP1850858A2 (de) * | 2005-02-10 | 2007-11-07 | Emory University | Polyethylenoxid-polymere mit entzündungshemmenden glycodendronen |
EP1712284B1 (de) * | 2005-04-15 | 2012-10-10 | Samsung Electronics Co., Ltd. | Methode zur Zelltrennung mit Benutzung hydrophober fester Träger |
US7749701B2 (en) * | 2005-08-11 | 2010-07-06 | Agilent Technologies, Inc. | Controlling use of oligonucleotide sequences released from arrays |
DE102005040211B4 (de) | 2005-08-16 | 2010-02-11 | Maquet Cardiopulmonary Ag | Verwendung von nichtionischen Estern in einer Beschichtung für mit Blut in Kontakt kommende Oberflächen und medizinische Vorrichtung |
US20070225795A1 (en) * | 2006-03-24 | 2007-09-27 | Juan Granada | Composite vascular prosthesis |
US7820172B1 (en) | 2006-06-01 | 2010-10-26 | Biosurface Engineering Technologies, Inc. | Laminin-derived multi-domain peptides |
EP2046350A4 (de) | 2006-06-22 | 2011-09-14 | Biosurface Eng Tech Inc | Zusammensetzungen und verfahren zur freisetzung eines bmp-2-amplifikators/coaktivators für verstärkte osteogenese |
AU2007317996B9 (en) * | 2006-11-01 | 2012-10-18 | Beckman Coulter, Inc. | Binding surfaces for affinity assays |
US20080187188A1 (en) * | 2007-02-07 | 2008-08-07 | Oleg Beletski | Systems, apparatuses and methods for facilitating efficient recognition of delivered content |
TR201809112T4 (tr) * | 2007-04-16 | 2018-07-23 | Regentis Biomaterials Ltd | İskele oluşturmak i̇çi̇n bi̇leşi̇mler ve yöntemler. |
CA2734577A1 (en) * | 2007-08-16 | 2009-02-26 | Carnegie Mellon University | Inflammation-regulating compositions and methods |
EP2247718B1 (de) | 2008-01-30 | 2019-01-16 | Asterias Biotherapeutics, Inc. | Synthetische oberflächen zur kultivierung von herzmuskelzellen aus stammzellen |
WO2009099552A2 (en) | 2008-01-30 | 2009-08-13 | Corning Incorporated | Cell culture article and screening |
US8329469B2 (en) | 2008-01-30 | 2012-12-11 | Geron Corporation | Swellable (meth)acrylate surfaces for culturing cells in chemically defined media |
US8513009B2 (en) | 2008-01-30 | 2013-08-20 | Geron Corporation | Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells |
DE102008027133A1 (de) * | 2008-05-30 | 2009-12-03 | Ls Medcap Gmbh | Vollsynthetisches Albumin-Analogon |
WO2010036257A1 (en) * | 2008-09-25 | 2010-04-01 | Celonova Biosciences, Inc. | Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface |
EP2442839B1 (de) * | 2009-04-09 | 2017-10-04 | The University of Queensland | Blockcopolymermischungen |
DE102009040880B4 (de) * | 2009-09-09 | 2012-10-18 | Andreas Hettich Gmbh & Co. Kg | Vorrichtung zur Durchführung von Tests zur Hämostase |
US20110117165A1 (en) * | 2009-11-18 | 2011-05-19 | Affinergy, Inc. | Implantable bone graft materials |
EP2761293B1 (de) * | 2011-09-30 | 2022-04-06 | Wake Forest University Health Sciences | Biogerüste zur bildung von motorendplatten und anderen spezialisierten gewebestrukturen |
SG11201811329UA (en) * | 2016-06-27 | 2019-01-30 | University Of Louisville Research Foundation Inc | Spheroids including biologically-relevant materials and related methods |
US10269569B2 (en) * | 2016-11-29 | 2019-04-23 | Taiwan Semiconductor Manufacturing Company, Ltd. | Semiconductor device and methods of manufacture |
JP7192314B2 (ja) * | 2017-08-31 | 2022-12-20 | 東洋インキScホールディングス株式会社 | 蛋白質、細胞又は微生物の接着抑制剤、並びにその用途 |
US10941274B1 (en) | 2020-09-01 | 2021-03-09 | King Abdulaziz University | Nanoparticle-infused ABS filament for 3D-printed materials and uses for neutron detection and discrimination |
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US4264766A (en) | 1877-09-19 | 1981-04-28 | Hoffmann-La Roche Inc. | Immunological diagnostic reagents |
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
SE420733B (sv) | 1974-05-30 | 1981-10-26 | Exploaterings Ab Tbf | Gelprodukt, innehallande tiosulfatgrupper samt sett for framstellning derav |
US3966580A (en) | 1974-09-16 | 1976-06-29 | The University Of Utah | Novel protein-immobilizing hydrophobic polymeric membrane, process for producing same and apparatus employing same |
SE430062B (sv) | 1977-03-04 | 1983-10-17 | Pharmacia Fine Chemicals Ab | Kopplings- eller tioleringsreagens |
DE2850058A1 (de) | 1978-11-18 | 1980-05-29 | Bayer Ag | Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4259474A (en) | 1979-09-25 | 1981-03-31 | Gaf Corporation | Sulfur-containing polyoxyalkylenes |
SE8102194L (sv) | 1981-04-06 | 1982-10-07 | Pharmacia Ab | Terapeutiskt aktiv organisk forening och farmaceutisk beredning innehallande denna |
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US5516703A (en) | 1993-08-20 | 1996-05-14 | The University Of Utah | Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands |
US6284503B1 (en) | 1993-08-20 | 2001-09-04 | University Of Utah Research Foundation | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
BE1008955A3 (fr) | 1994-11-14 | 1996-10-01 | Univ Catholique Louvain | Procede d'obtention de biomateriaux et produits obtenus. |
US5783178A (en) | 1994-11-18 | 1998-07-21 | Supratek Pharma. Inc. | Polymer linked biological agents |
US5565188A (en) | 1995-02-24 | 1996-10-15 | Nanosystems L.L.C. | Polyalkylene block copolymers as surface modifiers for nanoparticles |
-
1997
- 1997-01-15 US US08/784,203 patent/US6284503B1/en not_active Expired - Lifetime
-
1998
- 1998-01-15 AT AT98903402T patent/ATE501249T1/de not_active IP Right Cessation
- 1998-01-15 IL IL13096198A patent/IL130961A0/xx active IP Right Grant
- 1998-01-15 CA CA002277995A patent/CA2277995C/en not_active Expired - Fee Related
- 1998-01-15 AU AU60182/98A patent/AU740877B2/en not_active Expired
- 1998-01-15 JP JP53443898A patent/JP2001512565A/ja active Pending
- 1998-01-15 EP EP98903402A patent/EP1002066B1/de not_active Expired - Lifetime
- 1998-01-15 KR KR1019997006456A patent/KR20000070229A/ko not_active Application Discontinuation
- 1998-01-15 WO PCT/US1998/000337 patent/WO1998031734A1/en not_active Application Discontinuation
- 1998-01-15 DE DE69842166T patent/DE69842166D1/de not_active Expired - Lifetime
-
1999
- 1999-07-14 IL IL130961A patent/IL130961A/en not_active IP Right Cessation
-
2001
- 2001-09-04 US US09/946,079 patent/US6670199B2/en not_active Expired - Fee Related
-
2003
- 2003-12-30 US US10/748,061 patent/US7208299B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6284503B1 (en) | 2001-09-04 |
US20020019037A1 (en) | 2002-02-14 |
CA2277995C (en) | 2003-03-18 |
ATE501249T1 (de) | 2011-03-15 |
KR20000070229A (ko) | 2000-11-25 |
US6670199B2 (en) | 2003-12-30 |
US20040170964A1 (en) | 2004-09-02 |
US7208299B2 (en) | 2007-04-24 |
IL130961A (en) | 2009-02-11 |
WO1998031734A1 (en) | 1998-07-23 |
IL130961A0 (en) | 2001-01-28 |
CA2277995A1 (en) | 1998-07-23 |
EP1002066A1 (de) | 2000-05-24 |
JP2001512565A (ja) | 2001-08-21 |
AU6018298A (en) | 1998-08-07 |
EP1002066A4 (de) | 2004-12-01 |
AU740877B2 (en) | 2001-11-15 |
EP1002066B1 (de) | 2011-03-09 |
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