DE69818495D1 - Trennung von aminen - Google Patents

Trennung von aminen

Info

Publication number
DE69818495D1
DE69818495D1 DE69818495T DE69818495T DE69818495D1 DE 69818495 D1 DE69818495 D1 DE 69818495D1 DE 69818495 T DE69818495 T DE 69818495T DE 69818495 T DE69818495 T DE 69818495T DE 69818495 D1 DE69818495 D1 DE 69818495D1
Authority
DE
Germany
Prior art keywords
enantiomer
acid
compound
dextrorotatory
racemic mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69818495T
Other languages
English (en)
Other versions
DE69818495T2 (de
Inventor
Antoni Torrens-Jover
Jordi Frigola-Constansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Application granted granted Critical
Publication of DE69818495D1 publication Critical patent/DE69818495D1/de
Publication of DE69818495T2 publication Critical patent/DE69818495T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Gyroscopes (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
DE69818495T 1997-07-10 1998-07-06 Trennung von aminen Expired - Fee Related DE69818495T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES9701538 1997-07-10
ES009701538A ES2130079B1 (es) 1997-07-10 1997-07-10 Resolucion de aminas
PCT/ES1998/000195 WO1999002500A1 (es) 1997-07-10 1998-07-06 Resolucion de aminas

Publications (2)

Publication Number Publication Date
DE69818495D1 true DE69818495D1 (de) 2003-10-30
DE69818495T2 DE69818495T2 (de) 2004-07-01

Family

ID=8300022

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69818495T Expired - Fee Related DE69818495T2 (de) 1997-07-10 1998-07-06 Trennung von aminen

Country Status (12)

Country Link
US (1) US6187930B1 (de)
EP (1) EP1024137B1 (de)
JP (1) JP2001509505A (de)
AT (1) ATE250585T1 (de)
AU (1) AU8111798A (de)
CA (1) CA2295800A1 (de)
DE (1) DE69818495T2 (de)
DK (1) DK1024137T3 (de)
ES (2) ES2130079B1 (de)
NO (1) NO314581B1 (de)
PT (1) PT1024137E (de)
WO (1) WO1999002500A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5986135A (en) * 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US6687187B2 (en) * 2000-08-11 2004-02-03 Phonak Ag Method for directional location and locating system
US20040142929A1 (en) * 2001-07-06 2004-07-22 Ramon Merce-Vidal Derivatives of aryl (or heteroaryl) azolylcarbinoles for the treatment of urinary incontinence
US7182210B2 (en) 2003-08-19 2007-02-27 Rock-Tenn Shared Services, Llc Adjustable shelving system
TW200533657A (en) * 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
ES2244326B1 (es) * 2004-04-05 2007-02-16 Laboratorios Del Dr. Esteve, S.A. Combinacion de substancias activas.
EP1584335A3 (de) * 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Zusammensetzung aus Aktiva mit einer Carbinolverbindung und einem Opioid
US20060040924A1 (en) * 2004-06-22 2006-02-23 Laboratorios Dr. Esteve S.A. Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of renal colic
EP1671953A1 (de) 2004-12-17 2006-06-21 Laboratorios Del Dr. Esteve, S.A. Verfahren zur Herstellung von Cizolirtine und dessen Enantiomeren
EP1671968A1 (de) 2004-12-17 2006-06-21 Laboratorios Del Dr. Esteve, S.A. Verfahren zur Herstellung von Enantiomeren von Thienylazolylalkoxyethanamines
EP1674465A1 (de) 2004-12-27 2006-06-28 Laboratorios Del Dr. Esteve, S.A. Verfahren zur Gewinnung der Enatiomeren der Thienylazolylalkoxyethanaminen
ATE486841T1 (de) * 2005-05-10 2010-11-15 Teva Pharma Verfahren zur herstellung von pregabalin und salzen daraus
EP1879854B1 (de) * 2005-05-10 2011-09-07 Teva Pharmaceutical Industries Ltd Optische lösung a us 3-carbamoylmethyl-5-methyl-hexansäure
US7897589B2 (en) * 2005-07-15 2011-03-01 Laboratorios Del Dr. Esteve, S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
EP1757587A1 (de) * 2005-07-15 2007-02-28 Laboratorios Del Dr. Esteve, S.A. Substituierte Pyrazolinderivate, ihre Herstellung und Verwendung als Arzneimittel
EP1743892A1 (de) * 2005-07-15 2007-01-17 Laboratorios del Dr. Esteve S.A. Substituierte Pyrazolin Verbindungen, deren Herstellung und Verwendung als Medikament
EP1743890A1 (de) * 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. 4,5-Dihydro-1H-Pyrazol-Derivative, Verfahren zur Herstellung und ihre Verwendung als Medikamente.
KR20080034205A (ko) * 2005-09-19 2008-04-18 테바 파마슈티컬 인더스트리즈 리미티드 (ｓ)-프레가발린의 신규한 합성을 위한 주요 중간체인 키랄3-카르바모일메틸-5-메틸 헥산산
EP1820502A1 (de) 2006-02-10 2007-08-22 Laboratorios Del Dr. Esteve, S.A. Wirkstoffzusammensetzungen enthaltend Azolycarbinolderivate
KR20100107500A (ko) * 2008-06-23 2010-10-05 테바 파마슈티컬 인더스트리즈 리미티드 (ｓ) 또는 (ｒ)-이소-부틸-글루타릭 에스테르의 입체선택적 효소 합성방법
EP2151234A1 (de) * 2008-07-28 2010-02-10 Laboratorios Del. Dr. Esteve, S.A. Pharmazeutische Formulierung mit einer CB1-Rezeptorverbindung in einer festen Lösung und/oder festen Dispersion
US20100291151A1 (en) * 2009-04-21 2010-11-18 Auspex Pharmaceuticals, Inc. 1-methylpyrazole modulators of substance p, calcitonin gene-related peptide, adrenergic receptor, and/or 5-ht receptor
JP2011057619A (ja) * 2009-09-10 2011-03-24 Tokai Univ 光学活性アミン化合物の製造方法、並びに、ジアステレオマー塩及びその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2742147B1 (fr) * 1995-12-06 1998-02-27 Esteve Labor Dr Procede de separation de carbinols
DE19601745C1 (de) * 1996-01-19 1997-10-09 Gruenenthal Gmbh Verfahren zur Racematspaltung von Tramadol

Also Published As

Publication number Publication date
NO20000089D0 (no) 2000-01-07
AU8111798A (en) 1999-02-08
CA2295800A1 (en) 1999-01-21
ES2130079A1 (es) 1999-06-16
DK1024137T3 (da) 2003-12-22
JP2001509505A (ja) 2001-07-24
PT1024137E (pt) 2004-01-30
NO314581B1 (no) 2003-04-14
EP1024137B1 (de) 2003-09-24
US6187930B1 (en) 2001-02-13
EP1024137A1 (de) 2000-08-02
ES2209158T3 (es) 2004-06-16
NO20000089L (no) 2000-02-22
ES2130079B1 (es) 2000-01-16
DE69818495T2 (de) 2004-07-01
ATE250585T1 (de) 2003-10-15
WO1999002500A1 (es) 1999-01-21

Similar Documents

Publication Publication Date Title
ATE250585T1 (de) Trennung von aminen
ES2112830T3 (es) 4-pirimidinaminas y -pirimidindiaminas sustituidas en n, un procedimiento para su preparacion y su uso como medicamentos.
DK0574313T3 (da) 1,4-disubstituerede piperaziner til behandling af sygdomme i centralnervesystemet og neuroendocrine sygdomme
MXPA03011062A (es) Resolucion optica de (1-bencil-4-metilpiperidin-3-il)-metilamina y el uso de la misma para la preparacion de derivados de pirrolo 2,3-pirimidina como inhibidores de proteina quinasas.
EA199700186A1 (ru) Новые дипептидные амидины, используемые в качестве ингибиторов тромбина
KR890002030A (ko) 메데토 미딘의 d 및 1 에난티오머, 그 분리 방법 및 이를 포함하는 제약학적 조성물
PT80117B (pt) Processo para a preparacao de 2-oxindole-1-carboxamidas 3-substituidas uteis como agentes analgesicos e anti-inflamatorios
ES2020981B3 (es) Fenilsulfonamidas sustituidas.
DE3689555T2 (de) Herstellung von aliphatischen Polyaminen.
ATE45728T1 (de) Verfahren zur herstellung bestimmter enantiomerenpaare von permethrinsaeure-alpha-cyano-3-phenoxy-4-fluor-b nzyl-ester.
DE3887957D1 (de) Mischung zur Absorption von sauren Gasen.
DE69231843D1 (de) Verfahren zur Herstellung von insektiziden, nematiziden und akariziden 2-Aryl-3-subst.-5- trifluormethylpyrrolen aus N-(subst. Benzyl)-2,2,2-trifluoracetimidoylchloriden
RO92320B (ro) Procedeu pentru prepararea clorurii de carnitinnitril optic activ
ES2182086T3 (es) Nuevos derivados de peptidil-arginina aldehido.
ATE315782T1 (de) Karl-fischer-reagenz
ATE60788T1 (de) Derivat von p-aminophenol mit mucrosekretolytischer fluessiger und antipyretischer wirksamkeit, dessen verfahren zur herstellung und dessen pharmazeutische zusammensetzungen.
DK162095C (da) Fremgangsmaade til fremstilling af thiotetronsyre
DE3578988D1 (de) Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln.
EA200000069A1 (ru) Способ получения 4-замещенных-1h-индол-3-глиоксамидов
DK159083D0 (da) Fremgangsmade til fremstilling af n-(1,3-dithiolan-2-yliden)-aniliner
AU1486683A (en) N-(p-sulfophenyl)-cinnamamide
NO990159D0 (no) FremgangsmÕte for fremstilling av enantiomerisk anrikede N-acylazetidin-2-karboksylsyrer
DE50210377D1 (de) Verfahren zur herstellung von bis (trifluormethyl)imido-salzen
ATE45575T1 (de) Prostacycline.
DK0426098T3 (da) Fremstilling af et lægemiddel til behandling af hyperphosphatæmisk status

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee