DE69812343D1 - Feste pharmazeutische formulierungen enthaltend eine physische mischung aus sulphoalkylethercyclodextrin und einem therapeutischen wirkstoff - Google Patents

Feste pharmazeutische formulierungen enthaltend eine physische mischung aus sulphoalkylethercyclodextrin und einem therapeutischen wirkstoff

Info

Publication number
DE69812343D1
DE69812343D1 DE69812343T DE69812343T DE69812343D1 DE 69812343 D1 DE69812343 D1 DE 69812343D1 DE 69812343 T DE69812343 T DE 69812343T DE 69812343 T DE69812343 T DE 69812343T DE 69812343 D1 DE69812343 D1 DE 69812343D1
Authority
DE
Germany
Prior art keywords
sae
pharmaceutical formulations
sulphoalkylethercyclodextrin
active substance
formulations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69812343T
Other languages
English (en)
Other versions
DE69812343T2 (de
Inventor
K Stella
James Macginity
A Rajewski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cydex Pharmaceuticals Inc
Original Assignee
Cydex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cydex Inc filed Critical Cydex Inc
Application granted granted Critical
Publication of DE69812343D1 publication Critical patent/DE69812343D1/de
Publication of DE69812343T2 publication Critical patent/DE69812343T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
DE69812343T 1997-05-05 1998-04-20 Feste pharmazeutische formulierungen enthaltend eine physische mischung aus sulphoalkylethercyclodextrin und einem therapeutischen wirkstoff Expired - Lifetime DE69812343T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US851006 1997-05-05
US08/851,006 US5874418A (en) 1997-05-05 1997-05-05 Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
PCT/US1998/008221 WO1998050077A1 (en) 1997-05-05 1998-04-20 Solid pharmaceutical formulations containing a physical mixture of sulfoalkyl ether cyclodextrin and a therapeutic agent

Publications (2)

Publication Number Publication Date
DE69812343D1 true DE69812343D1 (de) 2003-04-24
DE69812343T2 DE69812343T2 (de) 2004-04-01

Family

ID=25309709

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69812343T Expired - Lifetime DE69812343T2 (de) 1997-05-05 1998-04-20 Feste pharmazeutische formulierungen enthaltend eine physische mischung aus sulphoalkylethercyclodextrin und einem therapeutischen wirkstoff

Country Status (10)

Country Link
US (1) US5874418A (de)
EP (1) EP0980262B1 (de)
JP (1) JP3745382B2 (de)
KR (1) KR100378031B1 (de)
AT (1) ATE234634T1 (de)
AU (1) AU729671B2 (de)
CA (1) CA2289202C (de)
DE (1) DE69812343T2 (de)
ES (1) ES2190075T3 (de)
WO (1) WO1998050077A1 (de)

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* Cited by examiner, † Cited by third party
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ATE234634T1 (de) 2003-04-15
JP3745382B2 (ja) 2006-02-15
KR100378031B1 (ko) 2003-04-16
CA2289202A1 (en) 1998-11-12
EP0980262A1 (de) 2000-02-23
JP2002503267A (ja) 2002-01-29
AU7153598A (en) 1998-11-27
AU729671B2 (en) 2001-02-08
DE69812343T2 (de) 2004-04-01
KR20010012233A (ko) 2001-02-15
EP0980262B1 (de) 2003-03-19
ES2190075T3 (es) 2003-07-16
CA2289202C (en) 2005-03-15
WO1998050077A1 (en) 1998-11-12
US5874418A (en) 1999-02-23

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