DE69731664D1 - Thrombininhibitoren - Google Patents
ThrombininhibitorenInfo
- Publication number
- DE69731664D1 DE69731664D1 DE69731664T DE69731664T DE69731664D1 DE 69731664 D1 DE69731664 D1 DE 69731664D1 DE 69731664 T DE69731664 T DE 69731664T DE 69731664 T DE69731664 T DE 69731664T DE 69731664 D1 DE69731664 D1 DE 69731664D1
- Authority
- DE
- Germany
- Prior art keywords
- thrombin inhibitors
- thrombin
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96202336 | 1996-08-23 | ||
PCT/EP1997/004579 WO1998007308A2 (en) | 1996-08-23 | 1997-08-19 | Thrombin inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69731664D1 true DE69731664D1 (de) | 2004-12-23 |
Family
ID=8224306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69731664T Expired - Lifetime DE69731664D1 (de) | 1996-08-23 | 1997-08-19 | Thrombininhibitoren |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0956293B1 (de) |
AR (1) | AR009302A1 (de) |
AT (1) | ATE282629T1 (de) |
AU (1) | AU4618197A (de) |
DE (1) | DE69731664D1 (de) |
ID (1) | ID18075A (de) |
IL (1) | IL121474A0 (de) |
TW (1) | TW515803B (de) |
WO (1) | WO1998007308A2 (de) |
ZA (1) | ZA977209B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0884325A1 (de) * | 1997-04-24 | 1998-12-16 | Akzo Nobel N.V. | Inhibitoren des Thrombins, die einen peptid-Heterocyclus aufweisen |
US5877156A (en) * | 1997-04-24 | 1999-03-02 | Akzo Nobel, N.V. | Thrombin inhibitors |
GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
CA2651043A1 (en) * | 2006-05-23 | 2007-12-06 | David C. Tully | Compounds and compositions as channel activating protease inhibitors |
JP2009538327A (ja) | 2006-05-23 | 2009-11-05 | アイアールエム・リミテッド・ライアビリティ・カンパニー | チャネル活性化プロテアーゼ阻害剤である化合物および組成物 |
EA016327B1 (ru) | 2007-02-09 | 2012-04-30 | Айрм Ллк | Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5672582A (en) * | 1993-04-30 | 1997-09-30 | Merck & Co., Inc. | Thrombin inhibitors |
SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
ZA951617B (en) * | 1994-03-04 | 1997-02-27 | Lilly Co Eli | Antithrombotic agents. |
EP0799240A1 (de) * | 1994-12-22 | 1997-10-08 | Biochem Pharma Inc | Heterozyklische keto arginin peptide als thrombin-inhibitoren |
US5827860A (en) * | 1995-06-07 | 1998-10-27 | Ortho Pharmaceutical Corporation | Peptidyl heterocycles useful in the treatment of thrombin related disorders |
IL119466A (en) * | 1995-11-03 | 2001-08-26 | Akzo Nobel Nv | Thrombin inhibitors, their preparation and pharmaceutical compositions containing them |
-
1997
- 1997-08-05 IL IL12147497A patent/IL121474A0/xx unknown
- 1997-08-12 ZA ZA9707209A patent/ZA977209B/xx unknown
- 1997-08-19 EP EP97944781A patent/EP0956293B1/de not_active Expired - Lifetime
- 1997-08-19 AT AT97944781T patent/ATE282629T1/de not_active IP Right Cessation
- 1997-08-19 WO PCT/EP1997/004579 patent/WO1998007308A2/en active IP Right Grant
- 1997-08-19 DE DE69731664T patent/DE69731664D1/de not_active Expired - Lifetime
- 1997-08-19 AU AU46181/97A patent/AU4618197A/en not_active Abandoned
- 1997-08-22 AR ARP970103820A patent/AR009302A1/es unknown
- 1997-08-22 ID IDP972947A patent/ID18075A/id unknown
- 1997-08-30 TW TW086112645A patent/TW515803B/zh active
Also Published As
Publication number | Publication date |
---|---|
IL121474A0 (en) | 1998-02-08 |
WO1998007308A2 (en) | 1998-02-26 |
ZA977209B (en) | 1998-02-20 |
ID18075A (id) | 1998-02-26 |
WO1998007308A3 (en) | 2000-08-24 |
AR009302A1 (es) | 2000-04-12 |
AU4618197A (en) | 1998-03-06 |
TW515803B (en) | 2003-01-01 |
EP0956293A1 (de) | 1999-11-17 |
ATE282629T1 (de) | 2004-12-15 |
EP0956293B1 (de) | 2004-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |