ATE282629T1 - Thrombininhibitoren - Google Patents

Thrombininhibitoren

Info

Publication number
ATE282629T1
ATE282629T1 AT97944781T AT97944781T ATE282629T1 AT E282629 T1 ATE282629 T1 AT E282629T1 AT 97944781 T AT97944781 T AT 97944781T AT 97944781 T AT97944781 T AT 97944781T AT E282629 T1 ATE282629 T1 AT E282629T1
Authority
AT
Austria
Prior art keywords
thrombin inhibitors
thrombin
inhibitors
Prior art date
Application number
AT97944781T
Other languages
English (en)
Inventor
Boeckel Constant Adriaan A Van
Anton Egbert Peter Adang
Jacobus Albertus Maria Peters
Johannes Bernardus Ma Rewinkel
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE282629T1 publication Critical patent/ATE282629T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97944781T 1996-08-23 1997-08-19 Thrombininhibitoren ATE282629T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96202336 1996-08-23
PCT/EP1997/004579 WO1998007308A2 (en) 1996-08-23 1997-08-19 Thrombin inhibitors

Publications (1)

Publication Number Publication Date
ATE282629T1 true ATE282629T1 (de) 2004-12-15

Family

ID=8224306

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97944781T ATE282629T1 (de) 1996-08-23 1997-08-19 Thrombininhibitoren

Country Status (10)

Country Link
EP (1) EP0956293B1 (de)
AR (1) AR009302A1 (de)
AT (1) ATE282629T1 (de)
AU (1) AU4618197A (de)
DE (1) DE69731664D1 (de)
ID (1) ID18075A (de)
IL (1) IL121474A0 (de)
TW (1) TW515803B (de)
WO (1) WO1998007308A2 (de)
ZA (1) ZA977209B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0884325A1 (de) * 1997-04-24 1998-12-16 Akzo Nobel N.V. Inhibitoren des Thrombins, die einen peptid-Heterocyclus aufweisen
US5877156A (en) * 1997-04-24 1999-03-02 Akzo Nobel, N.V. Thrombin inhibitors
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
US7951823B2 (en) 2006-05-23 2011-05-31 Irm Llc Compounds and compositions as channel activating protease inhibitors
EP2019837B1 (de) 2006-05-23 2011-03-23 Irm Llc Verbindungen und zusammensetzungen als kanalaktivierende protease-hemmer
EP2117537A1 (de) 2007-02-09 2009-11-18 Irm Llc Verbindungen und zusammensetzungen als kanalaktivierende protease-hemmer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672582A (en) * 1993-04-30 1997-09-30 Merck & Co., Inc. Thrombin inhibitors
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
ZA951617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
AU4250896A (en) * 1994-12-22 1996-07-10 Biochem Pharma Inc. Heterocyclic keto arginine peptides as thrombin inhibitors
US5827860A (en) * 1995-06-07 1998-10-27 Ortho Pharmaceutical Corporation Peptidyl heterocycles useful in the treatment of thrombin related disorders
IL119466A (en) * 1995-11-03 2001-08-26 Akzo Nobel Nv Thrombin inhibitors, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ID18075A (id) 1998-02-26
EP0956293B1 (de) 2004-11-17
WO1998007308A3 (en) 2000-08-24
WO1998007308A2 (en) 1998-02-26
ZA977209B (en) 1998-02-20
TW515803B (en) 2003-01-01
AU4618197A (en) 1998-03-06
AR009302A1 (es) 2000-04-12
DE69731664D1 (de) 2004-12-23
IL121474A0 (en) 1998-02-08
EP0956293A1 (de) 1999-11-17

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties