DE69701418D1 - Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben - Google Patents
Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von ProbenInfo
- Publication number
- DE69701418D1 DE69701418D1 DE69701418T DE69701418T DE69701418D1 DE 69701418 D1 DE69701418 D1 DE 69701418D1 DE 69701418 T DE69701418 T DE 69701418T DE 69701418 T DE69701418 T DE 69701418T DE 69701418 D1 DE69701418 D1 DE 69701418D1
- Authority
- DE
- Germany
- Prior art keywords
- resuspension
- localization
- samples
- washing
- collection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title 2
- 230000004807 localization Effects 0.000 title 1
- 238000007885 magnetic separation Methods 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 238000005406 washing Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/644,909 US5888835A (en) | 1996-05-10 | 1996-05-10 | Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69701418D1 true DE69701418D1 (de) | 2000-04-20 |
DE69701418T2 DE69701418T2 (de) | 2000-07-06 |
Family
ID=24586856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69701418T Expired - Lifetime DE69701418T2 (de) | 1996-05-10 | 1997-05-08 | Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben |
Country Status (5)
Country | Link |
---|---|
US (1) | US5888835A (de) |
EP (1) | EP0806665B1 (de) |
JP (1) | JP4208100B2 (de) |
CA (1) | CA2199211A1 (de) |
DE (1) | DE69701418T2 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143578A (en) * | 1996-05-10 | 2000-11-07 | Bayer Corporation | Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology |
DE10012007T1 (de) * | 1998-05-01 | 2012-01-26 | Gen-Probe Inc. | Automatisches Diagnoseanalysegerät und Verfahren |
JP2001091521A (ja) * | 1999-09-21 | 2001-04-06 | Olympus Optical Co Ltd | 自動分析装置 |
US6672458B2 (en) * | 2000-05-19 | 2004-01-06 | Becton, Dickinson And Company | System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample |
DE10136060A1 (de) * | 2001-07-25 | 2003-02-13 | Roche Diagnostics Gmbh | System zur Separation von magnetisch anziehbaren Partikeln |
WO2003086637A1 (en) * | 2002-04-12 | 2003-10-23 | Instrumentation Laboratory Company | Immunoassay probe |
US20040157219A1 (en) * | 2003-02-06 | 2004-08-12 | Jianrong Lou | Chemical treatment of biological samples for nucleic acid extraction and kits therefor |
CH697124A5 (de) * | 2004-01-08 | 2008-05-15 | Qiagen Instr Ag | Trennen und Reinigen einer Suspension mit magnetischen Mikropartikeln. |
US20050239091A1 (en) * | 2004-04-23 | 2005-10-27 | Collis Matthew P | Extraction of nucleic acids using small diameter magnetically-responsive particles |
WO2005116613A2 (en) * | 2004-05-24 | 2005-12-08 | Bayer Corporation | Vial presence indicator for vial-bearing rack |
US8211386B2 (en) | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
WO2006017428A2 (en) * | 2004-08-03 | 2006-02-16 | Becton, Dickinson And Company | Use of magnetic material to direct isolation of compounds and fractionation of multipart samples |
US7731899B2 (en) | 2007-02-08 | 2010-06-08 | Biokit, S.A. | Apparatus and methods for dispensing sample holders |
US8728413B2 (en) * | 2007-02-08 | 2014-05-20 | Biokit, S.A. | Reagent container pack |
US8795609B2 (en) * | 2007-02-08 | 2014-08-05 | Biokit, S.A. | Magnetic particle washing station |
US7731414B2 (en) * | 2007-02-08 | 2010-06-08 | Instrumentation Laboratory Company | Reagent cartridge mixing tube |
CA2692186C (en) * | 2007-06-29 | 2019-03-12 | Becton, Dickinson And Company | Methods for extraction and purification of components of biological samples |
US20110097240A1 (en) * | 2008-06-12 | 2011-04-28 | Hitachi High-Technologies Corporation | Analyzer using magnetic particles |
WO2012012779A2 (en) | 2010-07-23 | 2012-01-26 | Beckman Coulter Inc. | System and method including analytical units |
WO2016043291A1 (ja) * | 2014-09-19 | 2016-03-24 | 協和メデックス株式会社 | 磁性担体粒子の洗浄方法、磁性担体粒子の洗浄装置、及び磁性担体粒子を用いる免疫学的測定方法 |
JP6858008B2 (ja) * | 2016-11-30 | 2021-04-14 | シスメックス株式会社 | 粒子分散装置及び粒子分散方法 |
CN110082549B (zh) * | 2018-01-25 | 2023-10-10 | 深圳市新产业生物医学工程股份有限公司 | 清洗装置及化学发光检测仪 |
CN110883039B (zh) * | 2018-09-11 | 2021-06-04 | 深圳市新产业生物医学工程股份有限公司 | 吸附机构、清洗装置、化学发光检测仪及清洗方法 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4265855A (en) * | 1978-11-03 | 1981-05-05 | Electro-Nucleonics, Inc. | System for performing immunochemical and other analyses involving phase separation |
US4698302A (en) * | 1983-05-12 | 1987-10-06 | Advanced Magnetics, Inc. | Enzymatic reactions using magnetic particles |
US4628037A (en) * | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
GB8401368D0 (en) * | 1984-01-19 | 1984-02-22 | Amersham Int Plc | Assay method |
JP2510152B2 (ja) * | 1985-11-19 | 1996-06-26 | オリンパス光学工業株式会社 | 自動分析装置 |
US4661408A (en) * | 1986-03-18 | 1987-04-28 | E.I. Du Pont De Nemours And Company | Coated chromium dioxide particles |
CH669266A5 (fr) * | 1986-10-14 | 1989-02-28 | Serono Diagnostics Ltd | Appareil d'analyse automatique pour le dosage d'anticorps ou d'antigenes dans un liquide biologique. |
US5395688A (en) * | 1987-10-26 | 1995-03-07 | Baxter Diagnostics Inc. | Magnetically responsive fluorescent polymer particles |
US5091206A (en) * | 1987-10-26 | 1992-02-25 | Baxter Diagnostics Inc. | Process for producing magnetically responsive polymer particles and application thereof |
GB8800419D0 (en) * | 1988-01-08 | 1988-02-10 | Amersham Int Plc | Method for measuring free fraction of ligands in biological fluids |
US5256532A (en) * | 1988-05-02 | 1993-10-26 | Zynaxis Technologies, Inc. | Methods, reagents and test kits for determination of subpopulations of biological entities |
US5147529A (en) * | 1988-08-10 | 1992-09-15 | E. I. Du Pont De Nemours And Company | Method for automatically processing magnetic solid phase reagents |
US5104808A (en) * | 1988-08-26 | 1992-04-14 | Laska Paul F | Method and apparatus for effecting a plurality of assays on a plurality of samples in an automatic analytical device |
US5108933A (en) * | 1988-09-16 | 1992-04-28 | Immunicon Corporation | Manipulation of colloids for facilitating magnetic separations |
DE3840462A1 (de) * | 1988-12-01 | 1990-06-07 | Berthold Lab Prof R | Verfahren und vorrichtung zur messung der chemilumineszenz |
IL94212A0 (en) * | 1989-07-24 | 1991-01-31 | Tri Tech Partners And Triton B | Automated analytical apparatus and method |
US5183638A (en) * | 1989-12-04 | 1993-02-02 | Kabushiki Kaisha Nittec | Automatic immunity analysis apparatus with magnetic particle separation |
US5200084A (en) * | 1990-09-26 | 1993-04-06 | Immunicon Corporation | Apparatus and methods for magnetic separation |
JP2548626B2 (ja) * | 1990-11-21 | 1996-10-30 | 三井製薬工業株式会社 | 免疫自動分析装置 |
US5128103A (en) * | 1990-12-14 | 1992-07-07 | E. I. Du Pont De Nemours And Company | Apparatus for automatically processing magnetic solid phase reagents |
US5491068A (en) * | 1991-02-14 | 1996-02-13 | Vicam, L.P. | Assay method for detecting the presence of bacteria |
CA2384535C (en) * | 1991-03-04 | 2006-08-15 | Bayer Corporation | Automated analyzer |
US5466574A (en) * | 1991-03-25 | 1995-11-14 | Immunivest Corporation | Apparatus and methods for magnetic separation featuring external magnetic means |
US5186827A (en) * | 1991-03-25 | 1993-02-16 | Immunicon Corporation | Apparatus for magnetic separation featuring external magnetic means |
US5232665A (en) * | 1991-07-26 | 1993-08-03 | E. I. Du Pont De Nemours And Company | Multi-linear automatic apparatus for processing immunoassays |
DE69329135T2 (de) * | 1992-09-24 | 2001-01-11 | Amersham Pharmacia Biotech Uk Ltd., Little Chalfont | Verfahren und Vorrichtung zur magnetischen Abscheidung |
EP0589636B1 (de) * | 1992-09-24 | 2000-08-02 | Amersham Pharmacia Biotech UK Limited | Verfahren und Vorrichtung zur magnetischen Abscheidung |
US5374531A (en) * | 1993-03-22 | 1994-12-20 | Zynaxis, Inc. | Immunoassay for determination of cells |
DE4429155A1 (de) * | 1994-08-17 | 1996-02-22 | Hans Schiesl | Meßanordnung und Verfahren zur Durchführung luminometrischer Reihenanalysen sowie Mehrfachküvette zur Aufnahme von Flüssigkeitsproben hierfür |
-
1996
- 1996-05-10 US US08/644,909 patent/US5888835A/en not_active Expired - Lifetime
-
1997
- 1997-03-05 CA CA002199211A patent/CA2199211A1/en not_active Abandoned
- 1997-05-08 DE DE69701418T patent/DE69701418T2/de not_active Expired - Lifetime
- 1997-05-08 EP EP97303120A patent/EP0806665B1/de not_active Expired - Lifetime
- 1997-05-12 JP JP12118597A patent/JP4208100B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2199211A1 (en) | 1997-11-10 |
EP0806665B1 (de) | 2000-03-15 |
MX9701411A (es) | 1997-11-29 |
JP4208100B2 (ja) | 2009-01-14 |
EP0806665A1 (de) | 1997-11-12 |
JPH1096732A (ja) | 1998-04-14 |
US5888835A (en) | 1999-03-30 |
DE69701418T2 (de) | 2000-07-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US |