DE69701418D1 - Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben - Google Patents

Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben

Info

Publication number
DE69701418D1
DE69701418D1 DE69701418T DE69701418T DE69701418D1 DE 69701418 D1 DE69701418 D1 DE 69701418D1 DE 69701418 T DE69701418 T DE 69701418T DE 69701418 T DE69701418 T DE 69701418T DE 69701418 D1 DE69701418 D1 DE 69701418D1
Authority
DE
Germany
Prior art keywords
resuspension
localization
samples
washing
collection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69701418T
Other languages
English (en)
Other versions
DE69701418T2 (de
Inventor
Steven E Bushnell
Tina K Garyantes
Michael L Malek
Howard J Kirchick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Corp filed Critical Bayer Corp
Publication of DE69701418D1 publication Critical patent/DE69701418D1/de
Application granted granted Critical
Publication of DE69701418T2 publication Critical patent/DE69701418T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809Multifield plates or multicontainer arrays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/113332Automated chemical analysis with conveyance of sample along a test line in a container or rack

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69701418T 1996-05-10 1997-05-08 Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben Expired - Lifetime DE69701418T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/644,909 US5888835A (en) 1996-05-10 1996-05-10 Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology

Publications (2)

Publication Number Publication Date
DE69701418D1 true DE69701418D1 (de) 2000-04-20
DE69701418T2 DE69701418T2 (de) 2000-07-06

Family

ID=24586856

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69701418T Expired - Lifetime DE69701418T2 (de) 1996-05-10 1997-05-08 Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben

Country Status (5)

Country Link
US (1) US5888835A (de)
EP (1) EP0806665B1 (de)
JP (1) JP4208100B2 (de)
CA (1) CA2199211A1 (de)
DE (1) DE69701418T2 (de)

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JP2001091521A (ja) * 1999-09-21 2001-04-06 Olympus Optical Co Ltd 自動分析装置
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
DE10136060A1 (de) * 2001-07-25 2003-02-13 Roche Diagnostics Gmbh System zur Separation von magnetisch anziehbaren Partikeln
WO2003086637A1 (en) * 2002-04-12 2003-10-23 Instrumentation Laboratory Company Immunoassay probe
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
CH697124A5 (de) * 2004-01-08 2008-05-15 Qiagen Instr Ag Trennen und Reinigen einer Suspension mit magnetischen Mikropartikeln.
US20050239091A1 (en) * 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
WO2005116613A2 (en) * 2004-05-24 2005-12-08 Bayer Corporation Vial presence indicator for vial-bearing rack
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
WO2006017428A2 (en) * 2004-08-03 2006-02-16 Becton, Dickinson And Company Use of magnetic material to direct isolation of compounds and fractionation of multipart samples
US7731899B2 (en) 2007-02-08 2010-06-08 Biokit, S.A. Apparatus and methods for dispensing sample holders
US8728413B2 (en) * 2007-02-08 2014-05-20 Biokit, S.A. Reagent container pack
US8795609B2 (en) * 2007-02-08 2014-08-05 Biokit, S.A. Magnetic particle washing station
US7731414B2 (en) * 2007-02-08 2010-06-08 Instrumentation Laboratory Company Reagent cartridge mixing tube
CA2692186C (en) * 2007-06-29 2019-03-12 Becton, Dickinson And Company Methods for extraction and purification of components of biological samples
US20110097240A1 (en) * 2008-06-12 2011-04-28 Hitachi High-Technologies Corporation Analyzer using magnetic particles
WO2012012779A2 (en) 2010-07-23 2012-01-26 Beckman Coulter Inc. System and method including analytical units
WO2016043291A1 (ja) * 2014-09-19 2016-03-24 協和メデックス株式会社 磁性担体粒子の洗浄方法、磁性担体粒子の洗浄装置、及び磁性担体粒子を用いる免疫学的測定方法
JP6858008B2 (ja) * 2016-11-30 2021-04-14 シスメックス株式会社 粒子分散装置及び粒子分散方法
CN110082549B (zh) * 2018-01-25 2023-10-10 深圳市新产业生物医学工程股份有限公司 清洗装置及化学发光检测仪
CN110883039B (zh) * 2018-09-11 2021-06-04 深圳市新产业生物医学工程股份有限公司 吸附机构、清洗装置、化学发光检测仪及清洗方法

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Also Published As

Publication number Publication date
CA2199211A1 (en) 1997-11-10
EP0806665B1 (de) 2000-03-15
MX9701411A (es) 1997-11-29
JP4208100B2 (ja) 2009-01-14
EP0806665A1 (de) 1997-11-12
JPH1096732A (ja) 1998-04-14
US5888835A (en) 1999-03-30
DE69701418T2 (de) 2000-07-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US