DE69413470D1 - Verfahren und Vorrichtung zum Trennen von Teilchen - Google Patents

Verfahren und Vorrichtung zum Trennen von Teilchen

Info

Publication number
DE69413470D1
DE69413470D1 DE69413470T DE69413470T DE69413470D1 DE 69413470 D1 DE69413470 D1 DE 69413470D1 DE 69413470 T DE69413470 T DE 69413470T DE 69413470 T DE69413470 T DE 69413470T DE 69413470 D1 DE69413470 D1 DE 69413470D1
Authority
DE
Germany
Prior art keywords
separation method
particle separation
particle
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69413470T
Other languages
English (en)
Other versions
DE69413470T2 (de
Inventor
Totaro Imasaka
Kazuo Isaka
Toshikazu Ohnishi
Takeshi Miyazaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canon Inc
Original Assignee
Canon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP16919593A external-priority patent/JPH0724309A/ja
Priority claimed from JP16919693A external-priority patent/JPH0724310A/ja
Priority claimed from JP5169199A external-priority patent/JPH0724311A/ja
Application filed by Canon Inc filed Critical Canon Inc
Publication of DE69413470D1 publication Critical patent/DE69413470D1/de
Application granted granted Critical
Publication of DE69413470T2 publication Critical patent/DE69413470T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6073—Construction of the column body in open tubular form
    • G01N30/6078—Capillaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/04—Acceleration by electromagnetic wave pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N2030/285—Control of physical parameters of the fluid carrier electrically driven carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6026—Fluid seals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6082—Construction of the column body transparent to radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

Landscapes

  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE69413470T 1993-07-08 1994-07-07 Verfahren und Vorrichtung zum Trennen von Teilchen Expired - Lifetime DE69413470T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP16919593A JPH0724309A (ja) 1993-07-08 1993-07-08 粒子の分離方法及び装置
JP16919693A JPH0724310A (ja) 1993-07-08 1993-07-08 粒子の分離方法及び装置
JP5169199A JPH0724311A (ja) 1993-07-08 1993-07-08 粒子の分離方法及び装置

Publications (2)

Publication Number Publication Date
DE69413470D1 true DE69413470D1 (de) 1998-10-29
DE69413470T2 DE69413470T2 (de) 1999-03-04

Family

ID=27323137

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69413470T Expired - Lifetime DE69413470T2 (de) 1993-07-08 1994-07-07 Verfahren und Vorrichtung zum Trennen von Teilchen

Country Status (3)

Country Link
US (1) US6224732B1 (de)
EP (1) EP0635994B1 (de)
DE (1) DE69413470T2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19708658B4 (de) * 1997-03-04 2004-08-05 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren zum Sortieren und/oder Selektieren von bezüglich ihrer Masse, Größe und/oder Oberflächenbeschaffenheiten unterschiedlichen Partikeln
WO2002009483A1 (en) * 2000-07-26 2002-01-31 The Regents Of The University Of California Manipulation of live cells and inorganic objects with optical micro beam arrays
US20030007894A1 (en) * 2001-04-27 2003-01-09 Genoptix Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
US6833542B2 (en) 2000-11-13 2004-12-21 Genoptix, Inc. Method for sorting particles
US20020160470A1 (en) * 2000-11-13 2002-10-31 Genoptix Methods and apparatus for generating and utilizing linear moving optical gradients
US6744038B2 (en) 2000-11-13 2004-06-01 Genoptix, Inc. Methods of separating particles using an optical gradient
US6936811B2 (en) * 2000-11-13 2005-08-30 Genoptix, Inc. Method for separating micro-particles
US20020121443A1 (en) * 2000-11-13 2002-09-05 Genoptix Methods for the combined electrical and optical identification, characterization and/or sorting of particles
US6784420B2 (en) 2000-11-13 2004-08-31 Genoptix, Inc. Method of separating particles using an optical gradient
US20020123112A1 (en) * 2000-11-13 2002-09-05 Genoptix Methods for increasing detection sensitivity in optical dielectric sorting systems
US6778724B2 (en) 2000-11-28 2004-08-17 The Regents Of The University Of California Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
US20030194755A1 (en) * 2001-04-27 2003-10-16 Genoptix, Inc. Early detection of apoptotic events and apoptosis using optophoretic analysis
US20040009540A1 (en) * 2001-04-27 2004-01-15 Genoptix, Inc Detection and evaluation of cancer cells using optophoretic analysis
US20040023310A1 (en) * 2001-04-27 2004-02-05 Genoptix, Inc Quantitative determination of protein kinase C activation using optophoretic analysis
DE10157032A1 (de) * 2001-11-21 2003-06-12 Evotec Ag Verfahren und Vorrichtung zum Sortieren von Partikeln
US20030211461A1 (en) * 2002-05-01 2003-11-13 Genoptix, Inc Optophoretic detection of durgs exhibiting inhibitory effect on Bcr-Abl positive tumor cells
US20040033539A1 (en) * 2002-05-01 2004-02-19 Genoptix, Inc Method of using optical interrogation to determine a biological property of a cell or population of cells
US20040053209A1 (en) * 2002-09-12 2004-03-18 Genoptix, Inc Detection and evaluation of topoisomerase inhibitors using optophoretic analysis
US20040067167A1 (en) * 2002-10-08 2004-04-08 Genoptix, Inc. Methods and apparatus for optophoretic diagnosis of cells and particles
US20040121307A1 (en) * 2002-12-19 2004-06-24 Genoptix, Inc Early detection of cellular differentiation using optophoresis
US20040121474A1 (en) * 2002-12-19 2004-06-24 Genoptix, Inc Detection and evaluation of chemically-mediated and ligand-mediated t-cell activation using optophoretic analysis
CN1860363B (zh) * 2003-08-28 2011-12-28 赛路拉公司 用于在微流通道网络中使用光学开关将细胞分类的方法和设备
US20050067337A1 (en) * 2003-09-30 2005-03-31 Hart Sean J. Laser optical separator and method for separating colloidal suspensions
JP4850711B2 (ja) * 2003-10-02 2012-01-11 ベックマン コールター， インコーポレイテッド 血液サンプルの有核赤血球の光学測定のリファレンスコントロール
AU2008236739B2 (en) * 2007-04-04 2014-05-29 Ande Corporation Plastic microfluidic separation and detection platforms
JP4525725B2 (ja) * 2007-10-18 2010-08-18 ソニー株式会社 光学測定部、光学測定用部材、及びこれらを配設した微小粒子測定装置、並びに微小粒子の光学測定方法
JP4539707B2 (ja) * 2007-10-25 2010-09-08 ソニー株式会社 微小粒子分取装置及び微小粒子分取用基板、並びに微小粒子分取方法
US20090117664A1 (en) * 2007-11-05 2009-05-07 Masataka Shinoda Liquid sending method of liquid in substrate channel and liquid sending apparatus
US10281385B2 (en) * 2007-12-21 2019-05-07 The United States Of America, As Represented By The Secretary Of The Navy Device for laser analysis and separation (LAS) of particles
JP4572973B2 (ja) * 2008-06-16 2010-11-04 ソニー株式会社 マイクロチップ及びマイクロチップにおける送流方法
US9550985B2 (en) * 2009-06-15 2017-01-24 Netbio, Inc. Methods for forensic DNA quantitation
CA3106132C (en) 2011-05-12 2023-08-29 Ande Corporation Methods and compositions for rapid multiplex amplification of str loci

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576916A (en) * 1982-04-26 1986-03-18 Akzo N.V. Electro-optical apparatus for microbial identification and enumeration
US4877721A (en) * 1986-05-15 1989-10-31 Eastman Kodak Company Photographic silver halide elements containing filter dyes
DE3736772A1 (de) * 1987-08-05 1989-05-11 Bundesrep Deutschland Laser-doppler-anemometer
US4887721A (en) 1987-11-30 1989-12-19 The United States Of America As Represented By The United States Department Of Energy Laser particle sorter
US5100627A (en) * 1989-11-30 1992-03-31 The Regents Of The University Of California Chamber for the optical manipulation of microscopic particles
US5133844A (en) * 1990-03-15 1992-07-28 United States Department Of Energy Method of electric field flow fractionation wherein the polarity of the electric field is periodically reversed
SE470347B (sv) * 1990-05-10 1994-01-31 Pharmacia Lkb Biotech Mikrostruktur för vätskeflödessystem och förfarande för tillverkning av ett sådant system
ATE172791T1 (de) * 1992-02-20 1998-11-15 Canon Kk Verfahren und messapparatur zur handhabung von teilchen
US5416576A (en) * 1994-01-03 1995-05-16 The Dow Chemical Company Serpentine coil spectrophotometer cell

Also Published As

Publication number Publication date
EP0635994A1 (de) 1995-01-25
EP0635994B1 (de) 1998-09-23
DE69413470T2 (de) 1999-03-04
US6224732B1 (en) 2001-05-01

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Legal Events

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