DE69622677T2 - Hemmer der Prolaktinsynthese - Google Patents

Hemmer der Prolaktinsynthese

Info

Publication number
DE69622677T2
DE69622677T2 DE69622677T DE69622677T DE69622677T2 DE 69622677 T2 DE69622677 T2 DE 69622677T2 DE 69622677 T DE69622677 T DE 69622677T DE 69622677 T DE69622677 T DE 69622677T DE 69622677 T2 DE69622677 T2 DE 69622677T2
Authority
DE
Germany
Prior art keywords
prolactin
hetero
optionally substituted
useful
membered ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69622677T
Other languages
English (en)
Other versions
DE69622677D1 (de
Inventor
Nobuhiro Suzuki
Hirokazu Matsumoto
Shuichi Furuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69622677D1 publication Critical patent/DE69622677D1/de
Application granted granted Critical
Publication of DE69622677T2 publication Critical patent/DE69622677T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE69622677T 1995-12-08 1996-12-06 Hemmer der Prolaktinsynthese Expired - Fee Related DE69622677T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34504695 1995-12-08

Publications (2)

Publication Number Publication Date
DE69622677D1 DE69622677D1 (de) 2002-09-05
DE69622677T2 true DE69622677T2 (de) 2003-03-20

Family

ID=18373927

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622677T Expired - Fee Related DE69622677T2 (de) 1995-12-08 1996-12-06 Hemmer der Prolaktinsynthese

Country Status (5)

Country Link
US (1) US5977132A (de)
EP (1) EP0781774B1 (de)
AT (1) ATE221534T1 (de)
CA (1) CA2192283A1 (de)
DE (1) DE69622677T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313301B1 (en) 1997-08-13 2001-11-06 Takeda Chemical Industries, Ltd. Thienopyridine derivatives, their intermediates and production thereof
US6297255B1 (en) 1998-06-26 2001-10-02 Takeda Chemical Industries, Ltd. Thienopyridine compounds, their production and use
AR018935A1 (es) * 1998-06-26 2001-12-12 Takeda Chemical Industries Ltd Compuesto derivado de la tienopiridina, proceso para producirlo, composicion farmaceutica que lo contiene, y su uso para elaborar dicha composicion
BR9911564A (pt) * 1998-06-26 2001-10-09 Takeda Chemical Industries Ltd Composto, processo para produzir um composto, composição farmacêutica, processo para antagonizar o hormÈnio de liberação de gonadotropina em um mamìfero, e, uso de um composto
AU2635599A (en) * 1999-03-17 2000-10-04 Eugen Eigenmann Use of prolactin inhibitors for the treatment of fertility problems in animal species
US6534535B1 (en) 1999-08-12 2003-03-18 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
CA2423329A1 (en) * 2000-09-22 2003-03-20 Takeda Chemical Industries, Ltd. Solid preparations
WO2004014375A2 (en) * 2002-08-13 2004-02-19 Warner-Lambert Company Llc Fused bicyclic metalloproteinase inhibitors
PL1939204T6 (pl) 2005-10-19 2024-03-25 Kissei Pharmaceutical Co., Ltd. Skondensowana pochodna heterocykliczna, zawierająca ją kompozycja oraz jej zastosowanie medyczne
MX2009011923A (es) * 2007-05-10 2009-11-18 Amr Technology Inc Tetrahidrobenzo-1,4-diazepinas aril- y heteroaril-sustituidas y uso de las mismas para bloquear reabsorcion de norepinefrina, dopamina y serotonina.
US20220267347A1 (en) * 2019-07-29 2022-08-25 Sunshine Lake Pharma Co., Ltd. Substituted pyrimidinedione compounds and uses thereof
CN111574534B (zh) * 2020-05-25 2021-06-04 东莞市东阳光新药研发有限公司 苯基取代的噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮类化合物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE293824C (de) *
DE2006505A1 (de) * 1970-02-13 1971-08-26 Merck Patent Gmbh, 6100 Darmstadt Isoflavanoid ather und Verfahren zu ihrer Herstellung
WO1989002432A1 (en) * 1987-09-16 1989-03-23 Taiho Pharmaceutical Company, Limited Thienopyrimidine derivatives
JPH01213284A (ja) * 1988-02-22 1989-08-28 Sankyo Co Ltd チエノピリミジン−２，４−ジオン誘導体
JPH02225485A (ja) * 1989-02-27 1990-09-07 Taiho Yakuhin Kogyo Kk チエノピリミジン―３―酢酸誘導体
CA2036618C (en) * 1990-02-22 2002-10-29 Akira Morimoto Fused thiophene derivatives, their production and use
IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them
EP0687267B1 (de) * 1993-03-01 1999-09-01 MERCK SHARP & DOHME LTD. Pyrrolopyridinderivate als dopaminrezeptor liganden
WO1994020460A1 (en) * 1993-03-11 1994-09-15 Smithkline Beecham Corporation Chemical compounds
TW276256B (de) * 1993-08-26 1996-05-21 Takeda Pharm Industry Co Ltd
TW449600B (en) * 1994-04-19 2001-08-11 Takeda Chemical Industries Ltd Condensed-ring thiophene derivatives, their production and use
DE69623655T2 (de) * 1995-10-19 2003-04-24 Takeda Chemical Industries Ltd Chinolinderivate als gnrh antagonisten
CA2229205A1 (en) * 1995-10-19 1997-04-24 Shuichi Furuya Thienopyridine derivatives, their productions and use

Also Published As

Publication number Publication date
DE69622677D1 (de) 2002-09-05
EP0781774A3 (de) 1997-11-12
US5977132A (en) 1999-11-02
EP0781774B1 (de) 2002-07-31
ATE221534T1 (de) 2002-08-15
EP0781774A2 (de) 1997-07-02
CA2192283A1 (en) 1997-06-09

Similar Documents

Publication Publication Date Title
DE69622677T2 (de) Hemmer der Prolaktinsynthese
HU9600957D0 (en) Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
IL111258A0 (en) Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
ZA847731B (en) 2-amino-5-hydroxy-4-methylpyrimidine derivates
EA200400550A1 (ru) Бициклические производные оксопиридина и оксопиримидина
HU908257D0 (en) Process for the production of substituted 2-hydroxi-methyl-4-pyridone derivatives
IE801371L (en) Cyclic octapeptides
EP0455510A3 (en) Use of 5-ht1a receptor agonist compounds for inhibiting gastric acid secretion
ZA912913B (en) Novel 2,9-disubstituted-4h-pyrido(1,2-a)pyrimidin-4-ones
TW206970B (de)
NO163818C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte n-((4-piperidinyl)alkyl) bicykliske kondenserte oksazol- og tiazolaminer.
ES8705411A1 (es) Procedimiento para preparar derivados de 1-piperazinacarboxamida
NO881835D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive bicykliske forbindelser.
HUT38648A (en) Process for producing beta-lactam antibiotica and pharmaceutical, growth-controlling and antioxidative compositions
NO167803C (no) Analogifremgangsmaate til fremstilling av terapeutiskordskilleaktive n-(4-piperidinyl)bicyklisk kondenserte 2-imidazolaminderivater.
SE8300711L (sv) Mjoldrygealkaloider, forfarande for framstellning derav liksom farmaceutiska beredningar innehallande dessa foreningar
WO2000008027A1 (en) Kappa (op2) opioid receptor antagonists
NZ215439A (en) Benzo(c) 1,5 naphthyridines and pharmaceutical compositions
ES367158A1 (es) Procedimiento para la preparacion de 3-fenil-imidazo-tia- zol.
NO924701L (no) Amid-bundete pyridyl-benzosyrederivater for behandling avleukotrien-relaterte sykdommer
GB1422831A (en) Acylaminobenzimidazole derivatives
ES440479A1 (es) Procedimiento de obtencion de un derivado penicilinico.
JPS5242849A (en) Process for preparation of 2-alkylcyclopentadienylethanol
JPS5239656A (en) Process for preparing novel cyclopropylmethylamine derivatives

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP

8339 Ceased/non-payment of the annual fee