DE69530196D1 - Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen - Google Patents
Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauenInfo
- Publication number
- DE69530196D1 DE69530196D1 DE69530196T DE69530196T DE69530196D1 DE 69530196 D1 DE69530196 D1 DE 69530196D1 DE 69530196 T DE69530196 T DE 69530196T DE 69530196 T DE69530196 T DE 69530196T DE 69530196 D1 DE69530196 D1 DE 69530196D1
- Authority
- DE
- Germany
- Prior art keywords
- thawing
- aggregation
- rehydration
- peptides
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
- 238000004220 aggregation Methods 0.000 title abstract 2
- 230000002776 aggregation Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000010257 thawing Methods 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 3
- 230000008014 freezing Effects 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25296794A | 1994-06-02 | 1994-06-02 | |
PCT/GB1995/001277 WO1995033488A1 (en) | 1994-06-02 | 1995-06-02 | Method of preventing aggregation of various substances upon rehydration or thawing and compositions obtained thereby |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69530196D1 true DE69530196D1 (de) | 2003-05-08 |
DE69530196T2 DE69530196T2 (de) | 2003-11-20 |
Family
ID=22958303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530196T Revoked DE69530196T2 (de) | 1994-06-02 | 1995-06-02 | Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen |
Country Status (10)
Country | Link |
---|---|
US (2) | US6890512B2 (de) |
EP (1) | EP0762897B1 (de) |
JP (2) | JP4142095B2 (de) |
CN (1) | CN1188171C (de) |
AT (1) | ATE235919T1 (de) |
DE (1) | DE69530196T2 (de) |
DK (1) | DK0762897T3 (de) |
ES (1) | ES2194911T3 (de) |
PT (1) | PT762897E (de) |
WO (1) | WO1995033488A1 (de) |
Families Citing this family (66)
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WO1995033488A1 (en) * | 1994-06-02 | 1995-12-14 | Quadrant Holdings Cambridge Limited | Method of preventing aggregation of various substances upon rehydration or thawing and compositions obtained thereby |
US6586006B2 (en) | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
AU3570495A (en) | 1994-09-22 | 1996-04-09 | Quadrant Holdings Cambridge Limited | Compositions for use in rehydration and nutrition during athletic exercise and methods of making same |
US6964771B1 (en) * | 1995-06-07 | 2005-11-15 | Elan Drug Delivery Limited | Method for stably incorporating substances within dry, foamed glass matrices |
CN102416176A (zh) | 1995-07-27 | 2012-04-18 | 基因技术股份有限公司 | 稳定等渗的冻干蛋白质制剂 |
US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
US5762961A (en) * | 1996-02-09 | 1998-06-09 | Quadrant Holdings Cambridge Ltd. | Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof |
US5958455A (en) * | 1996-02-09 | 1999-09-28 | Quadrant Holdings Cambridge Ltd | Oral solid dosage forms, methods of making same and compositions thereof |
US6632648B1 (en) | 1996-05-14 | 2003-10-14 | Elan Drug Delivery Limited | Methods of terminal sterilization of fibrinogen |
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US6558901B1 (en) | 1997-05-02 | 2003-05-06 | Biomerieux Vitek | Nucleic acid assays |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
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US20050163725A1 (en) * | 2002-03-20 | 2005-07-28 | Blizzard Charles D. | Method for administration of growth hormone via pulmonary delivery |
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US20100080852A1 (en) * | 2007-05-03 | 2010-04-01 | Ronald Arthur Beyerinck | Phamaceutical composition comprising nanoparticles and casein |
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US20090081785A1 (en) * | 2007-09-24 | 2009-03-26 | Hememics Biotechnologies, Inc. | Desiccated Biologics And Methods Of Preparing The Same |
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US9233078B2 (en) * | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
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WO2010036226A1 (en) * | 2008-09-26 | 2010-04-01 | George Nelson | Process for treatment of rheumatoid arthritis, tremors/parkinson's disease and multiple sclerosis |
BRPI0921429B1 (pt) | 2008-11-07 | 2022-07-12 | Takeda Pharmaceutical Company Limited | Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável |
US9827205B2 (en) * | 2008-12-12 | 2017-11-28 | Mallinckrodt Pharma Ip Trading D.A.C. | Dry powder fibrin sealant |
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US9943075B2 (en) | 2010-02-17 | 2018-04-17 | Hememics Biotechnologies, Inc. | Preservation solutions for biologics and methods related thereto |
JP5341059B2 (ja) * | 2010-11-09 | 2013-11-13 | 株式会社大塚製薬工場 | 幹細胞懸濁液 |
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EP4088736A1 (de) | 2011-10-25 | 2022-11-16 | Prothena Biosciences Limited | Humanisierte anti-amyloid-antikörper-formulierungen und verfahren |
US20150044251A1 (en) * | 2011-12-23 | 2015-02-12 | Novartis Ag | Stable compositions for immunising against staphylococcus aureus |
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US20170332623A1 (en) * | 2016-03-28 | 2017-11-23 | Cook General Biotechnology Llc | Viable cell compositions, and methods related to same |
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US3557717A (en) | 1968-05-17 | 1971-01-26 | Gen Mills Inc | Process for making candy floss |
US3619294A (en) | 1968-07-15 | 1971-11-09 | Penick & Ford Ltd | Method of combining crystalline sugar with impregnating agents and products produced thereby |
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-
1995
- 1995-06-02 WO PCT/GB1995/001277 patent/WO1995033488A1/en active IP Right Grant
- 1995-06-02 DK DK95921031T patent/DK0762897T3/da active
- 1995-06-02 EP EP95921031A patent/EP0762897B1/de not_active Revoked
- 1995-06-02 CN CNB951944339A patent/CN1188171C/zh not_active Expired - Fee Related
- 1995-06-02 PT PT95921031T patent/PT762897E/pt unknown
- 1995-06-02 DE DE69530196T patent/DE69530196T2/de not_active Revoked
- 1995-06-02 JP JP50054296A patent/JP4142095B2/ja not_active Expired - Fee Related
- 1995-06-02 ES ES95921031T patent/ES2194911T3/es not_active Expired - Lifetime
- 1995-06-02 AT AT95921031T patent/ATE235919T1/de not_active IP Right Cessation
-
2001
- 2001-04-16 US US09/836,625 patent/US6890512B2/en not_active Expired - Fee Related
-
2005
- 2005-03-18 US US11/084,223 patent/US20050163750A1/en not_active Abandoned
-
2008
- 2008-01-21 JP JP2008010077A patent/JP2008179636A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US20050163750A1 (en) | 2005-07-28 |
CN1188171C (zh) | 2005-02-09 |
PT762897E (pt) | 2003-07-31 |
US20010055583A1 (en) | 2001-12-27 |
EP0762897A1 (de) | 1997-03-19 |
CN1156967A (zh) | 1997-08-13 |
ES2194911T3 (es) | 2003-12-01 |
DE69530196T2 (de) | 2003-11-20 |
ATE235919T1 (de) | 2003-04-15 |
US6890512B2 (en) | 2005-05-10 |
EP0762897B1 (de) | 2003-04-02 |
JP4142095B2 (ja) | 2008-08-27 |
DK0762897T3 (da) | 2003-07-21 |
JPH10500990A (ja) | 1998-01-27 |
WO1995033488A1 (en) | 1995-12-14 |
JP2008179636A (ja) | 2008-08-07 |
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