HUE036214T2 - Eljárások aripiprazol-szuszpenzió és fagyasztva szárított készítmény elõállítására - Google Patents

Eljárások aripiprazol-szuszpenzió és fagyasztva szárított készítmény elõállítására

Info

Publication number
HUE036214T2
HUE036214T2 HUE08792242A HUE08792242A HUE036214T2 HU E036214 T2 HUE036214 T2 HU E036214T2 HU E08792242 A HUE08792242 A HU E08792242A HU E08792242 A HUE08792242 A HU E08792242A HU E036214 T2 HUE036214 T2 HU E036214T2
Authority
HU
Hungary
Prior art keywords
freeze
methods
dried formulation
aripiprazole suspension
producing aripiprazole
Prior art date
Application number
HUE08792242A
Other languages
English (en)
Inventor
Shogo Hiraoka
Takakuni Matsuda
Junichi Hatanaka
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of HUE036214T2 publication Critical patent/HUE036214T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HUE08792242A 2007-07-31 2008-07-30 Eljárások aripiprazol-szuszpenzió és fagyasztva szárított készítmény elõállítására HUE036214T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007200088 2007-07-31

Publications (1)

Publication Number Publication Date
HUE036214T2 true HUE036214T2 (hu) 2018-06-28

Family

ID=39816777

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE08792242A HUE036214T2 (hu) 2007-07-31 2008-07-30 Eljárások aripiprazol-szuszpenzió és fagyasztva szárított készítmény elõállítására

Country Status (28)

Country Link
US (6) US9457026B2 (hu)
EP (1) EP2170279B1 (hu)
JP (1) JP4879349B2 (hu)
KR (1) KR101546106B1 (hu)
CN (1) CN101801342B (hu)
AR (2) AR067747A1 (hu)
BR (1) BRPI0815382A2 (hu)
CA (1) CA2695178C (hu)
CO (1) CO6290634A2 (hu)
CY (1) CY1120165T1 (hu)
DK (1) DK2170279T3 (hu)
ES (1) ES2661037T3 (hu)
HR (1) HRP20180295T1 (hu)
HU (1) HUE036214T2 (hu)
IL (2) IL244186A0 (hu)
LT (1) LT2170279T (hu)
MX (1) MX2010001311A (hu)
MY (1) MY152789A (hu)
NO (1) NO2170279T3 (hu)
NZ (1) NZ582415A (hu)
PL (1) PL2170279T3 (hu)
PT (1) PT2170279T (hu)
RU (1) RU2483711C2 (hu)
SI (1) SI2170279T1 (hu)
TW (1) TWI410255B (hu)
UA (1) UA97286C2 (hu)
WO (1) WO2009017250A1 (hu)
ZA (1) ZA201000307B (hu)

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* Cited by examiner, † Cited by third party
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HUE036214T2 (hu) * 2007-07-31 2018-06-28 Otsuka Pharma Co Ltd Eljárások aripiprazol-szuszpenzió és fagyasztva szárított készítmény elõállítására
PT105058B (pt) 2010-04-21 2013-04-17 Hovione Farmaciencia S A Processo para processamento de partículas de ingredientes activos farmacêuticos
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EP2667856B9 (en) 2011-01-24 2021-12-01 Otsuka Pharmaceutical Co., Ltd. Medical device containing a cake composition comprising aripiprazole as an active ingredient, and a cake composition comprising aripiprazole as an active ingredient
JO3410B1 (ar) * 2011-06-07 2019-10-20 Otsuka Pharma Co Ltd تركيبة أريبيبرازول مجفف بالتبريد
KR101103011B1 (ko) * 2011-10-13 2012-01-05 (주)일신오토클레이브 스크루 형 고압 발생 장치
CN102524261B (zh) * 2011-12-16 2014-12-03 辽宁师范大学 一种强力生根剂纳米制剂、其制备方法及应用
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AR090775A1 (es) * 2012-04-23 2014-12-03 Otsuka Pharma Co Ltd Preparado inyectable
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WO2017025930A1 (en) 2015-08-12 2017-02-16 Ftf Pharma Private Limited Oral solution of aripiprazole
CN106474058B (zh) * 2015-08-31 2020-01-07 南京诺瑞特医药科技有限公司 具有延长的保质期的阿立哌唑可注射悬浮液制剂
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CN108938578A (zh) * 2017-05-25 2018-12-07 万全万特制药（厦门）有限公司 阿立哌唑分散片及其制备方法
WO2021199076A1 (en) * 2020-03-30 2021-10-07 Cipla Limited Injectable aripiprazole formulation
EP4043008A1 (en) 2021-02-15 2022-08-17 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Method for the preparation of a pharmaceutical composition comprising aripiprazole
CN115554253B (zh) * 2022-10-14 2024-03-29 浙江圣兆药物科技股份有限公司 一种平稳释药的注射用阿立哌唑冻干制剂及其制备方法
CN117281784B (zh) * 2023-11-24 2024-02-27 山东则正医药技术有限公司 一种阿立哌唑注射剂及其制备方法和应用

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Also Published As

Publication number Publication date
US20100196486A1 (en) 2010-08-05
TWI410255B (zh) 2013-10-01
DK2170279T3 (en) 2018-03-12
IL244231A0 (en) 2016-04-21
US20180185358A1 (en) 2018-07-05
CA2695178C (en) 2015-06-23
ES2661037T3 (es) 2018-03-27
US9457026B2 (en) 2016-10-04
HRP20180295T1 (hr) 2018-03-23
TW200922636A (en) 2009-06-01
US20200246333A1 (en) 2020-08-06
ZA201000307B (en) 2011-04-28
CN101801342B (zh) 2012-07-11
RU2009149820A (ru) 2011-09-10
JP4879349B2 (ja) 2012-02-22
CA2695178A1 (en) 2009-02-05
UA97286C2 (ru) 2012-01-25
PT2170279T (pt) 2018-04-06
MY152789A (en) 2014-11-28
CO6290634A2 (es) 2011-06-20
RU2483711C2 (ru) 2013-06-10
CY1120165T1 (el) 2018-12-12
NZ582415A (en) 2012-05-25
NO2170279T3 (hu) 2018-05-26
PL2170279T3 (pl) 2018-05-30
KR20100057020A (ko) 2010-05-28
EP2170279B1 (en) 2017-12-27
AR067747A1 (es) 2009-10-21
BRPI0815382A2 (pt) 2015-02-10
IL244186A0 (en) 2016-04-21
AR117941A2 (es) 2021-09-08
LT2170279T (lt) 2018-03-12
EP2170279A1 (en) 2010-04-07
WO2009017250A1 (en) 2009-02-05
AU2008283251A1 (en) 2009-02-05
MX2010001311A (es) 2010-04-21
KR101546106B1 (ko) 2015-08-20
CN101801342A (zh) 2010-08-11
US20210361646A1 (en) 2021-11-25
US20240139177A1 (en) 2024-05-02
JP2010535151A (ja) 2010-11-18
US20170035752A1 (en) 2017-02-09
SI2170279T1 (en) 2018-04-30

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