DE69524405T2 - Photometrische Durchflussvorrichtung für kleine Probenvolumina - Google Patents

Photometrische Durchflussvorrichtung für kleine Probenvolumina

Info

Publication number
DE69524405T2
DE69524405T2 DE69524405T DE69524405T DE69524405T2 DE 69524405 T2 DE69524405 T2 DE 69524405T2 DE 69524405 T DE69524405 T DE 69524405T DE 69524405 T DE69524405 T DE 69524405T DE 69524405 T2 DE69524405 T2 DE 69524405T2
Authority
DE
Germany
Prior art keywords
flow device
small sample
sample volumes
photometric flow
photometric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69524405T
Other languages
English (en)
Other versions
DE69524405D1 (de
Inventor
Patrick Kaltenbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Deutschland GmbH
Original Assignee
Agilent Technologies Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Deutschland GmbH filed Critical Agilent Technologies Deutschland GmbH
Publication of DE69524405D1 publication Critical patent/DE69524405D1/de
Application granted granted Critical
Publication of DE69524405T2 publication Critical patent/DE69524405T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/74Optical detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0346Capillary cells; Microcells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/74Optical detectors
    • G01N2030/746Optical detectors detecting along the line of flow, e.g. axial
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/064Stray light conditioning
    • G01N2201/0642Light traps; baffles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optical Measuring Cells (AREA)
DE69524405T 1995-09-06 1995-09-06 Photometrische Durchflussvorrichtung für kleine Probenvolumina Expired - Lifetime DE69524405T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95113947A EP0762119B1 (de) 1995-09-06 1995-09-06 Photometrische Durchflussvorrichtung für kleine Probenvolumina

Publications (2)

Publication Number Publication Date
DE69524405D1 DE69524405D1 (de) 2002-01-17
DE69524405T2 true DE69524405T2 (de) 2002-05-23

Family

ID=8219582

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524405T Expired - Lifetime DE69524405T2 (de) 1995-09-06 1995-09-06 Photometrische Durchflussvorrichtung für kleine Probenvolumina

Country Status (4)

Country Link
US (1) US5917606A (de)
EP (1) EP0762119B1 (de)
JP (1) JPH09170981A (de)
DE (1) DE69524405T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013013975B3 (de) * 2013-08-23 2014-12-04 SunChrom Wissenschaftliche Geräte GmbH UV/VlS HPLC-Photometer

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US6224830B1 (en) 1998-01-30 2001-05-01 The Governors Of The University Of Alberta Absorbance cell for microfluid devices
US6075609A (en) * 1998-03-26 2000-06-13 Antek Industrial Instruments, Inc. Apparatus and methods for improving fluorescence detectors
US6188813B1 (en) * 1999-02-10 2001-02-13 Waters Investments Limited Flow cell, analyte measurement apparatus and methods related thereto
JP2001108619A (ja) * 1999-10-12 2001-04-20 Minolta Co Ltd 分析装置、試料操作針および試料取り出し方法
US6678051B2 (en) 2001-01-18 2004-01-13 Systec, Inc. Flow cells utilizing photometric techniques
EP1373856B1 (de) 2001-03-02 2018-11-14 Waters Technologies Corporation Fluoreszenzdetektorgeometrie
US20030110840A1 (en) * 2001-07-24 2003-06-19 Arriaga Edgar A. Systems and methods for detecting a particle
WO2003027028A1 (en) * 2001-09-28 2003-04-03 Applera Corporation Multi-capillary array electrophoresis device
US7250098B2 (en) * 2001-09-28 2007-07-31 Applera Corporation Multi-capillary array electrophoresis device
US7294839B2 (en) * 2002-10-08 2007-11-13 Ric Investements, Inc. Low volume sample cell and gas monitoring system using same
US6987897B2 (en) * 2002-10-31 2006-01-17 Luna Innovations Incorporated Fiber-optic flow cell and method relating thereto
AU2002952602A0 (en) * 2002-11-12 2002-11-28 Varian Australia Pty Ltd Flow through cell for optical spectroscopy
JP4005907B2 (ja) * 2002-12-12 2007-11-14 株式会社日立ハイテクノロジーズ キャピラリアレイ装置、その製造方法、及び電気泳動分析方法
US7050660B2 (en) 2003-04-07 2006-05-23 Eksigent Technologies Llc Microfluidic detection device having reduced dispersion and method for making same
US7894055B2 (en) * 2004-08-26 2011-02-22 The United States Of America As Represented By The Department Of Health And Human Services Flow-through, inlet-gas-temperature-controlled, solvent-resistant, thermal-expansion compensated cell for light spectroscopy
JP2006078414A (ja) * 2004-09-13 2006-03-23 Alps Electric Co Ltd 検査用プレート
US20060094004A1 (en) * 2004-10-28 2006-05-04 Akihisa Nakajima Micro-reactor, biological material inspection device, and microanalysis system
WO2006056236A1 (en) * 2004-11-25 2006-06-01 Agilent Technologies, Inc. Microfluidic arrangement with coupling device having a selectable optical detection portion
US7298472B2 (en) * 2004-12-28 2007-11-20 Rheodyne, Llc Fluid analysis apparatus
US7259840B1 (en) 2004-12-28 2007-08-21 Systec, Llc Fluid analysis apparatus
US7386199B2 (en) * 2005-12-22 2008-06-10 Palo Alto Research Center Incorporated Providing light to channels or portions
JP4781827B2 (ja) * 2006-01-24 2011-09-28 シャープ株式会社 分析方法および分析装置
CN100419406C (zh) * 2006-03-31 2008-09-17 洪陵成 流动光度分析流通池
US7545490B1 (en) * 2006-09-26 2009-06-09 Itt Manufacturing Enterprises, Inc. Microscope flow cell apparatus for raman analysis of a liquid
US8821799B2 (en) 2007-01-26 2014-09-02 Palo Alto Research Center Incorporated Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity
US9164037B2 (en) * 2007-01-26 2015-10-20 Palo Alto Research Center Incorporated Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances
US8629981B2 (en) * 2008-02-01 2014-01-14 Palo Alto Research Center Incorporated Analyzers with time variation based on color-coded spatial modulation
GB2457481B (en) 2008-02-14 2012-08-08 Starna Scient Ltd Fluorescence measurement cell
CN102150040B (zh) 2008-08-07 2014-12-31 安捷伦科技有限公司 多波长光源
DE102009025073A1 (de) * 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optischer Sensor
US8502969B2 (en) * 2009-12-16 2013-08-06 Boule Medical Ab Miniature flow-through cuvette and spectrophotometer containing the same
JP5854621B2 (ja) * 2011-04-07 2016-02-09 株式会社日立ハイテクノロジーズ 長光路長フローセル
US9029800B2 (en) 2011-08-09 2015-05-12 Palo Alto Research Center Incorporated Compact analyzer with spatial modulation and multiple intensity modulated excitation sources
US8723140B2 (en) 2011-08-09 2014-05-13 Palo Alto Research Center Incorporated Particle analyzer with spatial modulation and long lifetime bioprobes
US10451593B2 (en) * 2016-08-04 2019-10-22 Aa Holdings, Ltd. Detection system and method with nanostructure flow cell
WO2018037536A1 (ja) * 2016-08-25 2018-03-01 株式会社島津製作所 フローセル
US11422117B2 (en) * 2018-08-30 2022-08-23 KNAUER Wissenschaftliche Geräte GmbH Combined UV/Vis-absorption and conductivity flow cell for liquid chromatography

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US3783276A (en) * 1972-06-05 1974-01-01 Instrumentation Specialties Co Dual beam optical system
US3751173A (en) * 1972-08-24 1973-08-07 Micromedic Systems Inc Flowthrough cuvette
US4575424A (en) * 1984-03-01 1986-03-11 Isco, Inc. Chromatographic flow cell and method of making it
JPS63241337A (ja) * 1986-11-07 1988-10-06 Hitachi Ltd 光度計用フローセル
US5061361A (en) * 1989-03-06 1991-10-29 Hewlett-Packard Company Capillary zone electrophoresis cell system
EP0396163B1 (de) * 1989-04-14 1994-01-19 Kontron Instruments Holding N.V. Kapillare Durchflusszelle
DE4030699C1 (de) * 1990-09-28 1991-10-10 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
EP0488947B1 (de) * 1990-11-26 1995-02-15 Ciba-Geigy Ag Detektorzelle
US5184192A (en) * 1991-07-17 1993-02-02 Millipore Corporation Photometric apparatus with a flow cell coated with an amorphous fluoropolymer
US5273633A (en) * 1992-07-10 1993-12-28 Tiansong Wang Capillary multireflective cell
GB9314926D0 (en) * 1993-07-19 1993-09-01 Optiglass Ltd Spectrophotometer cell

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013013975B3 (de) * 2013-08-23 2014-12-04 SunChrom Wissenschaftliche Geräte GmbH UV/VlS HPLC-Photometer
EP2840393A1 (de) 2013-08-23 2015-02-25 SunChrom Wissenschaftliche Geräte GmbH UV/VIS HPLC-Fotometer

Also Published As

Publication number Publication date
JPH09170981A (ja) 1997-06-30
DE69524405D1 (de) 2002-01-17
EP0762119B1 (de) 2001-12-05
EP0762119A1 (de) 1997-03-12
US5917606A (en) 1999-06-29

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