DE69425823T2 - Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion - Google Patents
Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretionInfo
- Publication number
- DE69425823T2 DE69425823T2 DE69425823T DE69425823T DE69425823T2 DE 69425823 T2 DE69425823 T2 DE 69425823T2 DE 69425823 T DE69425823 T DE 69425823T DE 69425823 T DE69425823 T DE 69425823T DE 69425823 T2 DE69425823 T2 DE 69425823T2
- Authority
- DE
- Germany
- Prior art keywords
- pct
- inhibitors
- sec
- secretion
- chinoline derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9302005A SE9302005D0 (sv) | 1993-06-11 | 1993-06-11 | New active compounds |
SE9303970A SE9303970D0 (sv) | 1993-11-30 | 1993-11-30 | New active compounds |
PCT/SE1994/000552 WO1994029274A1 (en) | 1993-06-11 | 1994-06-08 | New active compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69425823D1 DE69425823D1 (de) | 2000-10-12 |
DE69425823T2 true DE69425823T2 (de) | 2001-01-18 |
Family
ID=26661770
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69425823T Expired - Fee Related DE69425823T2 (de) | 1993-06-11 | 1994-06-08 | Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion |
Country Status (25)
Country | Link |
---|---|
US (1) | US5889021A (de) |
EP (1) | EP0702672B1 (de) |
JP (1) | JP3623794B2 (de) |
CN (1) | CN1045955C (de) |
AT (1) | ATE196134T1 (de) |
AU (1) | AU680516B2 (de) |
BR (1) | BR9406772A (de) |
CA (1) | CA2164875A1 (de) |
CZ (1) | CZ326095A3 (de) |
DE (1) | DE69425823T2 (de) |
EE (1) | EE03123B1 (de) |
EG (1) | EG20435A (de) |
ES (1) | ES2150494T3 (de) |
FI (1) | FI955896A (de) |
HU (1) | HUT75122A (de) |
IL (1) | IL109685A (de) |
IS (1) | IS4164A (de) |
NO (1) | NO305799B1 (de) |
NZ (1) | NZ267740A (de) |
PL (1) | PL177766B1 (de) |
RU (1) | RU2142454C1 (de) |
SG (1) | SG47820A1 (de) |
SK (1) | SK154995A3 (de) |
TW (1) | TW261613B (de) |
WO (1) | WO1994029274A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5556863A (en) * | 1993-06-11 | 1996-09-17 | Astra Aktiebolag | Compound for gastric acid secretion inhibition |
US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
EP3398951B1 (de) * | 2015-12-31 | 2021-04-07 | Shanghai Pharmaceuticals Holding Co., Ltd. | Salz einer chinolonverbindung, polymorphe davon, herstellungsverfahren dafür, zusammensetzung und anwendungen |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US509804A (en) * | 1893-11-28 | Hoof-weight | ||
US3470186A (en) * | 1967-06-02 | 1969-09-30 | American Cyanamid Co | Substituted 4-anilino-3-quinolinecarboxylic acids and esters |
US4042702A (en) * | 1973-08-16 | 1977-08-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Halogen pyrazole derivatives, a method for producing these halogen pyrazole derivatives, medicaments containing and methods of using them |
LU69428A1 (de) * | 1974-02-20 | 1975-12-09 | ||
US4120972A (en) * | 1975-02-03 | 1978-10-17 | Smith Kline & French Laboratories Limited | Imidazolylmethylthio-ethyl isothiourea compounds |
ATA210876A (de) * | 1975-03-25 | 1979-01-15 | Byk Gulden Lomberg Chem Fab | Verfahren zur herstellung von neuen nidrofuryl- pyrazolderivaten |
GB1584378A (en) * | 1976-10-14 | 1981-02-11 | Byk Gulden Lomberg Chem Fab | (pyrazol-1-yl)-phenylacetic acids processes for their preparation and medicaments containing them |
LU78804A1 (de) * | 1977-12-30 | 1979-07-20 | Byk Gulden Lomberg Chem Fab | N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
US4243678A (en) * | 1977-12-30 | 1981-01-06 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Acylhydrocarbylaminoalkanoic acids, compositions and uses |
YU118379A (en) * | 1978-05-24 | 1983-02-28 | Byk Gulden Lomberg Chemischefa | Process for preparing phenylaminothiophene acetic acid |
US4343804A (en) * | 1979-03-26 | 1982-08-10 | A. H. Robins Company, Inc. | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds |
IL60742A (en) * | 1979-08-03 | 1983-12-30 | Byk Gulden Lomberg Chem Fab | Alkylpyrazolodiazepinone compounds,a process for their preparation and medicaments containing them |
EP0024638A1 (de) * | 1979-08-30 | 1981-03-11 | Byk Gulden Lomberg Chemische Fabrik GmbH | Substituierte Chinolinonalkancarbonsäuren, ihre Herstellung und sie enthaltende Arzneimittel |
ATE3291T1 (de) * | 1979-09-07 | 1983-05-15 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Substituierte oxirancarbonsaeuren, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende arzneimittel. |
ES8202780A1 (es) * | 1979-10-31 | 1982-03-01 | Byk Gulden Lomberg Chem Fab | Procedimiento para la preparacion de acidos oxocarboxilicos sustituidos |
US4381301A (en) * | 1980-05-07 | 1983-04-26 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments |
US4337267A (en) * | 1980-08-25 | 1982-06-29 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phenalkoxyalkyl- and phenoxyalkyl-substituted oxiranecarboxylic acids, their use and medicaments containing them |
DE3168902D1 (en) * | 1980-08-29 | 1985-03-28 | Byk Gulden Lomberg Chem Fab | Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them |
DE3262922D1 (en) * | 1981-02-02 | 1985-05-15 | Byk Gulden Lomberg Chem Fab | Tricyclic pyrrols, process for their preparation, their use and compositions containing them |
US4578381A (en) * | 1982-07-05 | 1986-03-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
DE3579436D1 (de) * | 1984-12-18 | 1990-10-04 | Otsuka Pharma Co Ltd | Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen. |
US5250527A (en) * | 1985-10-24 | 1993-10-05 | Smithkline & French Laboratories Limited | Pyridyl containing benzimidazoles, compositions and use |
GB8621425D0 (en) * | 1986-09-05 | 1986-10-15 | Smith Kline French Lab | Compounds |
GB8717644D0 (en) * | 1987-07-24 | 1987-09-03 | Smithkline Beckman Intercredit | Compounds |
GB8804447D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804445D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804443D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804448D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804444D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804446D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
US5049567A (en) * | 1988-02-25 | 1991-09-17 | Smithkline Beckman Intercredit B.V. | Substituted 4-aminoquinazoline derivatives and method of use |
CA2011086A1 (en) * | 1989-03-17 | 1990-09-17 | Karl-Heinz Geiss | 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom |
GB8908229D0 (en) * | 1989-04-12 | 1989-05-24 | Smithkline Beckman Intercredit | Compounds |
GB8910722D0 (en) * | 1989-05-10 | 1989-06-28 | Smithkline Beckman Intercredit | Compounds |
DE3917233A1 (de) * | 1989-05-26 | 1990-11-29 | Basf Ag | 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel |
GB8918265D0 (en) * | 1989-08-10 | 1989-09-20 | Smithkline Beckman Intercredit | Compounds |
JPH04211661A (ja) * | 1990-03-28 | 1992-08-03 | Otsuka Pharmaceut Co Ltd | キノリン誘導体及び該誘導体を含有する抗潰瘍剤 |
NZ241408A (en) * | 1991-01-29 | 1994-05-26 | Smithkline Beecham Intercredit | Strong acid salt of 3-butyryl-4-(2-methylphenylamino)-8-(2-hydroxy-ethoxy)quinoline and pharmaceutical compositions thereof |
GB9126438D0 (en) * | 1991-12-12 | 1992-02-12 | Smithkline Beecham Intercredit | New quinoline derivatives |
-
1994
- 1994-05-11 IS IS4164A patent/IS4164A/is unknown
- 1994-05-12 TW TW083104301A patent/TW261613B/zh active
- 1994-05-19 IL IL10968594A patent/IL109685A/en not_active IP Right Cessation
- 1994-06-07 EG EG33594A patent/EG20435A/xx active
- 1994-06-08 NZ NZ267740A patent/NZ267740A/en unknown
- 1994-06-08 DE DE69425823T patent/DE69425823T2/de not_active Expired - Fee Related
- 1994-06-08 AU AU70121/94A patent/AU680516B2/en not_active Ceased
- 1994-06-08 HU HU9503529A patent/HUT75122A/hu unknown
- 1994-06-08 CZ CZ953260A patent/CZ326095A3/cs unknown
- 1994-06-08 US US08/270,167 patent/US5889021A/en not_active Expired - Fee Related
- 1994-06-08 PL PL94311957A patent/PL177766B1/pl unknown
- 1994-06-08 CA CA002164875A patent/CA2164875A1/en not_active Abandoned
- 1994-06-08 ES ES94919046T patent/ES2150494T3/es not_active Expired - Lifetime
- 1994-06-08 BR BR9406772A patent/BR9406772A/pt not_active Application Discontinuation
- 1994-06-08 CN CN94192410A patent/CN1045955C/zh not_active Expired - Fee Related
- 1994-06-08 SG SG1996004567A patent/SG47820A1/en unknown
- 1994-06-08 RU RU96100758A patent/RU2142454C1/ru active
- 1994-06-08 JP JP50167595A patent/JP3623794B2/ja not_active Expired - Fee Related
- 1994-06-08 WO PCT/SE1994/000552 patent/WO1994029274A1/en active IP Right Grant
- 1994-06-08 AT AT94919046T patent/ATE196134T1/de not_active IP Right Cessation
- 1994-06-08 SK SK1549-95A patent/SK154995A3/sk unknown
- 1994-06-08 EP EP94919046A patent/EP0702672B1/de not_active Expired - Lifetime
- 1994-11-23 EE EE9400424A patent/EE03123B1/xx unknown
-
1995
- 1995-12-05 NO NO954928A patent/NO305799B1/no not_active IP Right Cessation
- 1995-12-08 FI FI955896A patent/FI955896A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
FI955896A0 (fi) | 1995-12-08 |
EE03123B1 (et) | 1998-10-15 |
NO954928D0 (no) | 1995-12-05 |
CN1045955C (zh) | 1999-10-27 |
US5889021A (en) | 1999-03-30 |
CZ326095A3 (en) | 1996-05-15 |
TW261613B (de) | 1995-11-01 |
AU7012194A (en) | 1995-01-03 |
DE69425823D1 (de) | 2000-10-12 |
IL109685A0 (en) | 1994-11-28 |
NZ267740A (en) | 1997-05-26 |
NO954928L (no) | 1995-12-05 |
JP3623794B2 (ja) | 2005-02-23 |
CN1125438A (zh) | 1996-06-26 |
ES2150494T3 (es) | 2000-12-01 |
SK154995A3 (en) | 1996-09-04 |
ATE196134T1 (de) | 2000-09-15 |
AU680516B2 (en) | 1997-07-31 |
PL177766B1 (pl) | 2000-01-31 |
HUT75122A (en) | 1997-04-28 |
EP0702672B1 (de) | 2000-09-06 |
HU9503529D0 (en) | 1996-02-28 |
PL311957A1 (en) | 1996-03-18 |
BR9406772A (pt) | 1996-02-21 |
WO1994029274A1 (en) | 1994-12-22 |
RU2142454C1 (ru) | 1999-12-10 |
CA2164875A1 (en) | 1994-12-22 |
EP0702672A1 (de) | 1996-03-27 |
NO305799B1 (no) | 1999-07-26 |
JPH09510951A (ja) | 1997-11-04 |
IL109685A (en) | 1999-03-12 |
SG47820A1 (en) | 1998-04-17 |
IS4164A (is) | 1994-12-12 |
EG20435A (en) | 1999-04-29 |
FI955896A (fi) | 1995-12-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW515798B (en) | Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof | |
SE9801526D0 (sv) | New compounds | |
SE9700661D0 (sv) | New compounds | |
ATE142199T1 (de) | Fluoralkoxybenzylaminoderivate stickstoffhaltiger heterocyclen | |
SE9602286D0 (sv) | New compounds | |
SE9802794D0 (sv) | New compounds | |
SE9802793D0 (sv) | New compounds | |
DE69425823T2 (de) | Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion | |
ES2121218T3 (es) | Fenoxifenilciclopentenilhidroxiureas. | |
MX9704136A (es) | Compuestos para la inhibicion de la secrecion de acido gastrico. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |