DE69422604T2 - Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren - Google Patents

Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren

Info

Publication number
DE69422604T2
DE69422604T2 DE69422604T DE69422604T DE69422604T2 DE 69422604 T2 DE69422604 T2 DE 69422604T2 DE 69422604 T DE69422604 T DE 69422604T DE 69422604 T DE69422604 T DE 69422604T DE 69422604 T2 DE69422604 T2 DE 69422604T2
Authority
DE
Germany
Prior art keywords
combine
electrophoretic separation
bioaffinity assay
bioaffinity
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69422604T
Other languages
English (en)
Other versions
DE69422604D1 (de
Inventor
Dr Ensing
Dr Oroszlan
Dr Paulus
Carlo S Dr Effenhauser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeptosens AG
Original Assignee
Zeptosens AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeptosens AG filed Critical Zeptosens AG
Publication of DE69422604D1 publication Critical patent/DE69422604D1/de
Application granted granted Critical
Publication of DE69422604T2 publication Critical patent/DE69422604T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/561Immunoelectrophoresis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20Immunohistochemistry assay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/961Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81Tube, bottle, or dipstick
DE69422604T 1994-03-08 1994-03-08 Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren Expired - Fee Related DE69422604T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94810146A EP0671626B1 (de) 1994-03-08 1994-03-08 Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren

Publications (2)

Publication Number Publication Date
DE69422604D1 DE69422604D1 (de) 2000-02-17
DE69422604T2 true DE69422604T2 (de) 2000-06-08

Family

ID=8218222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69422604T Expired - Fee Related DE69422604T2 (de) 1994-03-08 1994-03-08 Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren

Country Status (5)

Country Link
US (1) US5741639A (de)
EP (1) EP0671626B1 (de)
JP (1) JPH07311198A (de)
CA (1) CA2143999C (de)
DE (1) DE69422604T2 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824478A (en) * 1996-04-30 1998-10-20 Vysis, Inc. Diagnostic methods and probes
DE69729726T2 (de) * 1996-05-24 2005-07-07 Zeptosens Ag Verfahren zur trennung von wirkstoffgemischen mit kapillaraffinity-gelelektrophorese
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US6020209A (en) * 1997-04-28 2000-02-01 The United States Of America As Represented By The Secretary Of The Navy Microcapillary-based flow-through immunosensor and displacement immunoassay using the same
DE69835516D1 (de) * 1997-05-16 2006-09-21 Exact Sciences Corp Elektrophoretische analyse von molekülen mit immobilisierten sonden
US6368871B1 (en) * 1997-08-13 2002-04-09 Cepheid Non-planar microstructures for manipulation of fluid samples
JP2002505846A (ja) 1997-11-06 2002-02-26 モザイク テクノロジーズ シグナル増幅およびプロセッシングのための多重逐次的ポリヌクレオチド置換反応
AU753191B2 (en) 1997-11-25 2002-10-10 Exact Sciences Corporation Devices and methods for detecting target molecules in biological samples
ES2309022T3 (es) * 1997-12-24 2008-12-16 Cepheid Dispositivo y procedimiento para lisis.
AU760236B2 (en) 1998-06-18 2003-05-08 Exact Sciences Corporation Denaturing gradient affinity electrophoresis and methods of use thereof
JP2002518026A (ja) * 1998-06-19 2002-06-25 エムティー テクノロジー, インコーポレイテッド Srprnaを用いる非ウイルス生物の検出
DE59915204D1 (de) 1998-08-28 2010-10-28 Febit Holding Gmbh Verfahren zur herstellung von biochemischen reaktionsträgern
WO2000020643A1 (en) 1998-10-05 2000-04-13 Mosaic Technologies Reverse displacement assay for detection of nucleic acid sequences
US6887693B2 (en) 1998-12-24 2005-05-03 Cepheid Device and method for lysing cells, spores, or microorganisms
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
WO2000050870A1 (en) * 1999-02-26 2000-08-31 Mosaic Technologies Biochemical purification devices with immobilized capture probes and their uses
JP3957118B2 (ja) * 1999-05-18 2007-08-15 富士フイルム株式会社 試験片およびこの試験片からの画像情報読取装置
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
DE60014676T2 (de) 1999-05-28 2005-11-17 Cepheid, Sunnyvale Vorrichtung und verfahren zur analyse flüssiger proben
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US6294392B1 (en) 1999-07-21 2001-09-25 The Regents Of The University Of California Spatially-encoded analyte detection
US7838222B2 (en) * 1999-07-26 2010-11-23 United States of America/ NIH Methods, devices and kits for multiplex blotting of biological samples from multi-well plates
US7214477B1 (en) 1999-07-26 2007-05-08 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Layered device with capture regions for cellular analysis
ES2269171T3 (es) 1999-07-26 2007-04-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal Dispositivo en capas con regiones de captura para analisis celular.
US6969615B2 (en) * 1999-07-26 2005-11-29 20/20 Genesystems, Inc. Methods, devices, arrays and kits for detecting and analyzing biomolecules
US6423536B1 (en) 1999-08-02 2002-07-23 Molecular Dynamics, Inc. Low volume chemical and biochemical reaction system
US6406604B1 (en) * 1999-11-08 2002-06-18 Norberto A. Guzman Multi-dimensional electrophoresis apparatus
US7329388B2 (en) * 1999-11-08 2008-02-12 Princeton Biochemicals, Inc. Electrophoresis apparatus having staggered passage configuration
US6676815B1 (en) * 1999-12-30 2004-01-13 Roche Diagnostics Corporation Cell for electrochemical analysis of a sample
WO2001069258A1 (en) * 2000-03-16 2001-09-20 Biacore Ab Method for capturing analytes eluted from surface-bound ligands
DE10051396A1 (de) 2000-10-17 2002-04-18 Febit Ferrarius Biotech Gmbh Verfahren und Vorrichtung zur integrierten Synthese und Analytbestimmung an einem Träger
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
SE526185C2 (sv) 2001-11-07 2005-07-19 Prolight Diagnostics Ab Metod och anordning för immunanalys
WO2004048928A2 (en) * 2002-11-25 2004-06-10 The United States Of America As Represented By The Secretary Of Health And Human Services, Nih Method and apparatus for performing multiple simultaneous manipulations of biomolecules in a two-dimensional array
US8007724B2 (en) 2003-11-07 2011-08-30 Princeton Biochemicals, Inc. Electrophoresis apparatus having at least one auxiliary buffer passage
WO2005047882A2 (en) * 2003-11-07 2005-05-26 Princeton Biochemicals, Inc. Multi-dimensional electrophoresis apparatus
FR2862134B1 (fr) * 2003-11-12 2007-07-27 Sebia Sa Analyse et typage de proteines monoclonales par electrophorese capillaire et immunodeplacement
US20070148759A1 (en) * 2003-12-26 2007-06-28 Yoshinori Amano Biological sample discrimination device, biological sample discriminating method, and biological sample discriminating plate
EP1733232A1 (de) * 2004-03-23 2006-12-20 Quidel Corporation Hybridphasen-lateralfluss-test
US7378054B2 (en) * 2004-04-16 2008-05-27 Savvipharm Inc Specimen collecting, processing and analytical assembly
EP3527976A1 (de) * 2004-07-19 2019-08-21 ProteinSimple Verfahren und vorrichtungen zur analytdetektion
US7211184B2 (en) * 2004-08-04 2007-05-01 Ast Management Inc. Capillary electrophoresis devices
US20060160210A1 (en) * 2004-11-26 2006-07-20 Matsushita Electric Industrial Co., Ltd. Biological sample analysis plate
JPWO2006062149A1 (ja) * 2004-12-08 2008-06-12 松下電器産業株式会社 生体サンプル分析用プレート
CN101317086B (zh) * 2005-10-04 2013-08-14 海德威技术公司 分析物的微观流体检测
JP4749867B2 (ja) 2006-01-13 2011-08-17 パナソニック株式会社 電気泳動装置
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
WO2009009408A2 (en) * 2007-07-06 2009-01-15 Applied Biosystems Inc. Devices and methods for the detection of analytes
DE102010011560B4 (de) * 2010-03-16 2021-09-16 Gilupi Gmbh Biodetektor
US9696299B2 (en) 2010-11-01 2017-07-04 Norberto Guzman Integrated modular unit including an analyte concentrator microreactor device connected to a cartridge-cassette
US8865075B2 (en) 2010-11-01 2014-10-21 Princeton Biochemicals, Inc. Multi-task immunoaffinity device secured to a peripheral box and integrated to a capillary electrophoresis apparatus
US9927399B2 (en) 2013-11-12 2018-03-27 Nichiei Industry Co., Ltd. Capillary device for separation and analysis, microfluidic chip for separation and analysis, analysis method for proteins or peptides, electrophoresis instrument, and microfluidic chip electrophoresis instrument for separation and analysis
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
US11181479B2 (en) 2015-02-27 2021-11-23 Ldip, Llc Waveguide-based detection system with scanning light source
US11198118B2 (en) 2017-03-29 2021-12-14 Princeton Biochemicals, Inc. Integrated modular unit containing one or more analyte concentrator-microreactor devices to be coupled to a cartridge-cassette and methods of operation
CN110579603B (zh) * 2019-08-27 2022-08-30 武汉纺织大学 一种病毒检测传感器、一种检测病毒浓度的装置和方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199286A (en) * 1980-12-22 1986-05-09 Commw Serum Lab Commission A method of detecting antibodies or an antigenic or haptenic substance in a sample
FR2498331A1 (fr) * 1981-01-20 1982-07-23 Kadouche Jean Recipient reactif pour analyse notamment immunologique
US4865707A (en) * 1986-10-21 1989-09-12 Northeastern University Capillary gel electrophoresis columns
US5013669A (en) * 1988-06-01 1991-05-07 Smithkline Diagnostics, Inc. Mass producible biologically active solid phase devices
US5135627A (en) * 1990-10-15 1992-08-04 Soane Technologies, Inc. Mosaic microcolumns, slabs, and separation media for electrophoresis and chromatography
JPH05172815A (ja) * 1991-12-26 1993-07-13 Hitachi Ltd 免疫分析方法及びその分析装置

Also Published As

Publication number Publication date
DE69422604D1 (de) 2000-02-17
CA2143999C (en) 2005-10-18
JPH07311198A (ja) 1995-11-28
EP0671626A1 (de) 1995-09-13
US5741639A (en) 1998-04-21
EP0671626B1 (de) 2000-01-12
CA2143999A1 (en) 1995-09-09

Similar Documents

Publication Publication Date Title
DE69422604T2 (de) Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren
DE69612930D1 (de) Verfahren und Vorrichtung für die Reinigung von Werkstücken
DE69634860D1 (de) Vorrichtung und Verfahren zur Teilchentrennung
DE69836648D1 (de) Vorrichtung und Verfahren zur Trennung von Flüssigkeitsbestandteilen
DE69504254D1 (de) Vorrichtung und Verfahren zur Halbleitersbearbeitung
DE69606885T2 (de) Verfahren und vorrichtung zur durchführung von bereichserweiterten tcas
DE69804808D1 (de) Verfahren und vorrichtung zur reduzierung von verunreinigungen
DE69528807T2 (de) Verfahren und Vorrichtung zum Entdecken von Antwortgeräten
DE69822687D1 (de) Vorrichtung und Verfahren zur Zusammenfassung
DE69609608D1 (de) Vorrichtung und verfahren zur unterbrechungszuweisung
DE69838912D1 (de) Hydrothermisches elektrolytisches verfahren und vorrichtung
DE69629538D1 (de) Vorrichtung und Verfahren zur Trennung
DE69506936D1 (de) Verfahren zur automatischen Verkehrszeichenerkennung und das Verfahren durchführende Vorrichtung
DE69822923D1 (de) Verfahren und Vorrichtung zur Kantenhervorhebung
DE69817103D1 (de) Verfahren und Vorrichtung zur Folgeschätzung
DE69522327T2 (de) Verfahren und vorrichtung zur richtungsbestimmung
DE59708284D1 (de) Vorrichtung und verfahren zur formgebung von oberflächen
DE69120482D1 (de) Verfahren und Vorrichtung für die Flüssigkeitstrennung
DE69907826D1 (de) Verfahren und vorrichtung zum verbinden von coextrudierten nahrungsmitteln
DE59600288D1 (de) Verfahren und Vorrichtung zur Bearbeitung von Halbleitermaterial
DE69631467D1 (de) Verfahren und vorrichtung zur abtrennung von argon
DE69503266D1 (de) Verfahren und Vorrichtung zur Aufbereitung von Sand
DE69517965T2 (de) Verfahren und vorrichtung zum bruchtrennen von pleueln und dergleichen
ATE249299T1 (de) Verfahren und vorrichtung zum erzeugen von dünnbrammen
DE59800683D1 (de) Verfahren und vorrichtung zur direktreduktion von feinerzen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee