DE69132845D1 - Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen - Google Patents

Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen

Info

Publication number
DE69132845D1
DE69132845D1 DE69132845T DE69132845T DE69132845D1 DE 69132845 D1 DE69132845 D1 DE 69132845D1 DE 69132845 T DE69132845 T DE 69132845T DE 69132845 T DE69132845 T DE 69132845T DE 69132845 D1 DE69132845 D1 DE 69132845D1
Authority
DE
Germany
Prior art keywords
cks
proteins
protein
hcv protein
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69132845T
Other languages
English (en)
Other versions
DE69132845T2 (de
Inventor
Timothy Jon Bolling
Wlodzimierz Mandecki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69132845D1 publication Critical patent/DE69132845D1/de
Publication of DE69132845T2 publication Critical patent/DE69132845T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE69132845T 1990-08-24 1991-08-26 Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen Expired - Fee Related DE69132845T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57310390A 1990-08-24 1990-08-24

Publications (2)

Publication Number Publication Date
DE69132845D1 true DE69132845D1 (de) 2002-01-17
DE69132845T2 DE69132845T2 (de) 2002-08-01

Family

ID=24290678

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132845T Expired - Fee Related DE69132845T2 (de) 1990-08-24 1991-08-26 Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen

Country Status (7)

Country Link
EP (1) EP0475182B1 (de)
KR (1) KR920004577A (de)
AT (1) ATE210186T1 (de)
AU (1) AU650038B2 (de)
DE (1) DE69132845T2 (de)
DK (1) DK0475182T3 (de)
ES (1) ES2170051T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322769A (en) * 1988-03-11 1994-06-21 Abbott Laboratories Methods for using CKS fusion proteins
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
RO117329B1 (ro) 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
KR100352824B1 (ko) * 1999-11-26 2002-09-28 (주) 건축사 사무소 도시건축 날개부착형 방음 방화문

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0290516A4 (de) * 1986-10-24 1989-11-14 Jeffrey A Whitsett Proteine, die mit oberflächenwirksamen hydrophoben lungenwirkstoffen verbunden sind.
ES2012739T5 (es) * 1987-11-18 2001-12-01 Chiron Corp Diagnosticos para nanbv.
US5124255A (en) * 1988-03-11 1992-06-23 Abbott Laboratories CKS method of protein synthesis
US5120662A (en) * 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens

Also Published As

Publication number Publication date
EP0475182A2 (de) 1992-03-18
EP0475182B1 (de) 2001-12-05
DK0475182T3 (da) 2002-04-02
AU8277791A (en) 1992-03-12
ATE210186T1 (de) 2001-12-15
DE69132845T2 (de) 2002-08-01
KR920004577A (ko) 1992-03-27
AU650038B2 (en) 1994-06-09
ES2170051T3 (es) 2002-08-01
EP0475182A3 (en) 1992-10-21

Similar Documents

Publication Publication Date Title
DE3486179D1 (de) Verfahren zur herstellung vielkettige polypeptide oder proteine.
DE3781765D1 (de) Verfahren zur herstellung eines polypeptides.
KR890014738A (ko) 단백질 합성의 cks 방법
ATE46536T1 (de) Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren.
DE69534822D1 (de) Verfahren zur bakteriellen herstellung von heterologen polypeptiden mit disulfidbrücke
ATE299942T1 (de) Verfahren zur herstellung von natürlich gefalteten proteinen durch co-sekretion von molekularen chaperonen
ATE43138T1 (de) Herstellung von dns-sequenzen und deren verwendung zur mikrobiologischen herstellung von proteinen, insbesondere menschlichen serumalbuminen.
ATE423213T1 (de) Erhöhte expression in pflanzen durch verwendung von nicht-translierter leader-sequenz
DE122009000068I1 (de) Verfahren zur Herstellung von heterologen bispezifischen Antikörpern
ATE193727T1 (de) Verfahren zur herstellung von peroxidasen in einem aspergillusstamm
DE412557T1 (de) Wachstumsfaktor aus parenchymalen lebenszellen, dafuer kodierendes gen, verfahren zur herstellung dieses faktors und transformanten.
PT83968A (de) Verfahren zur verbesserung des expression von eukaryontenprotein
DE59410401D1 (de) VERFAHREN ZUR HERSTELLUNG REKOMBINANTER PilC-PROTEINE
DE69132845T2 (de) Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen
ATE220714T1 (de) Verfahren zur herstellung von proteinen
DE60037508D1 (de) Verfahren zur herstellung von rekombinantem insulin durch fusionsproteine
ATE199396T1 (de) Fusions-dns-sequenz, dadurch exprimiertes fusionsprotein und verfahren zur expression dieses fusionsproteins
ATE191007T1 (de) Verfahren zur rekombinanten herstellung von proteinen in der hefe hansenula
DE3586580D1 (de) Zur wirksamen gen-expression faehiger vektor und verwendung desselben.
ATE415422T1 (de) Menschliches gas-6 (growth arrest-specific gene 6) protein und dafür kodierende nukleinsäuren
DE58909205D1 (de) Expressionsvektor und Verfahren zur regulierbaren Herstellung von Proteinen in Eukaryonten.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee