DE69104475T2 - Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel. - Google Patents

Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel.

Info

Publication number
DE69104475T2
DE69104475T2 DE69104475T DE69104475T DE69104475T2 DE 69104475 T2 DE69104475 T2 DE 69104475T2 DE 69104475 T DE69104475 T DE 69104475T DE 69104475 T DE69104475 T DE 69104475T DE 69104475 T2 DE69104475 T2 DE 69104475T2
Authority
DE
Germany
Prior art keywords
pct
medicinal products
production
radical
urea derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69104475T
Other languages
English (en)
Other versions
DE69104475D1 (de
Inventor
Jean-Dominique Bourzat
Marc Capet
Claude Cotrel
Claude Guyon
Franco Manfre
Gerard Roussel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of DE69104475D1 publication Critical patent/DE69104475D1/de
Publication of DE69104475T2 publication Critical patent/DE69104475T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
DE69104475T 1990-03-13 1991-03-11 Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel. Expired - Fee Related DE69104475T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9003187A FR2659653B1 (fr) 1990-03-13 1990-03-13 Derives de l'uree, leur preparation et les medicaments les contenant.
PCT/FR1991/000195 WO1991013862A1 (fr) 1990-03-13 1991-03-11 Derives de l'uree, leur preparation et les medicaments les contenant

Publications (2)

Publication Number Publication Date
DE69104475D1 DE69104475D1 (de) 1994-11-10
DE69104475T2 true DE69104475T2 (de) 1995-02-23

Family

ID=9394668

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69104475T Expired - Fee Related DE69104475T2 (de) 1990-03-13 1991-03-11 Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel.

Country Status (16)

Country Link
US (1) US5338760A (de)
EP (1) EP0520016B1 (de)
JP (1) JPH05504970A (de)
AT (1) ATE112552T1 (de)
AU (1) AU637220B2 (de)
CA (1) CA2074365A1 (de)
DE (1) DE69104475T2 (de)
ES (1) ES2061236T3 (de)
FR (1) FR2659653B1 (de)
HU (1) HUT61574A (de)
IE (1) IE910821A1 (de)
IL (1) IL97511A0 (de)
NZ (1) NZ237379A (de)
PT (1) PT97027A (de)
WO (1) WO1991013862A1 (de)
ZA (1) ZA911767B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667864B2 (fr) * 1990-03-07 1994-08-05 Rhone Poulenc Sante Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
US5389682A (en) * 1992-09-18 1995-02-14 Warner-Lambert Company Agents acting at cholecystokinin receptors
FR2700167B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine et thiazolidine, leur préparation et les médicaments les contenant.
FR2700168B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
GB9307833D0 (en) * 1993-04-15 1993-06-02 Glaxo Inc Modulators of cholecystokinin and gastrin
CN1120845A (zh) * 1993-04-15 1996-04-17 格拉克索有限公司 具有cck和/或胃泌素拮抗活性的1，5-苯并二氮杂䓬衍生物
PT739903E (pt) * 1994-02-09 2002-05-31 Shionogi & Co Derivado carbamoilmetilureia
DE69615570T2 (de) * 1995-08-07 2002-07-11 Shionogi & Co Verfahren zur herstellung von carbamoylmethylharnstoff-derivaten
US6972296B2 (en) * 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
SI21096B (sl) * 2001-10-09 2012-05-31 Encysive Pharmaceuticals Inc Derivati karboksilne kisline ki inhibirajo vezavo integrinov na njihove receptorje
CN1934049A (zh) * 2004-03-16 2007-03-21 株式会社日本触媒 用于水硬材料的添加剂

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2646847B1 (fr) * 1989-05-12 1991-07-12 Rhone Poulenc Sante N-phenyl amides, leurs procedes de preparation et les medicaments les contenant

Also Published As

Publication number Publication date
HU9202919D0 (en) 1992-12-28
ES2061236T3 (es) 1994-12-01
IE910821A1 (en) 1991-09-25
HUT61574A (en) 1993-01-28
JPH05504970A (ja) 1993-07-29
CA2074365A1 (fr) 1991-09-14
PT97027A (pt) 1991-11-29
DE69104475D1 (de) 1994-11-10
IL97511A0 (en) 1992-06-21
EP0520016A1 (de) 1992-12-30
AU637220B2 (en) 1993-05-20
EP0520016B1 (de) 1994-10-05
AU7570491A (en) 1991-10-10
ZA911767B (en) 1991-12-24
NZ237379A (en) 1992-11-25
WO1991013862A1 (fr) 1991-09-19
ATE112552T1 (de) 1994-10-15
FR2659653A1 (fr) 1991-09-20
US5338760A (en) 1994-08-16
FR2659653B1 (fr) 1992-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee