DE69615570T2 - Verfahren zur herstellung von carbamoylmethylharnstoff-derivaten - Google Patents

Verfahren zur herstellung von carbamoylmethylharnstoff-derivaten

Info

Publication number
DE69615570T2
DE69615570T2 DE69615570T DE69615570T DE69615570T2 DE 69615570 T2 DE69615570 T2 DE 69615570T2 DE 69615570 T DE69615570 T DE 69615570T DE 69615570 T DE69615570 T DE 69615570T DE 69615570 T2 DE69615570 T2 DE 69615570T2
Authority
DE
Germany
Prior art keywords
carbamoyl methyl
derivatives
urine derivatives
producing
methyl urine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69615570T
Other languages
English (en)
Other versions
DE69615570D1 (de
Inventor
Haruo Koike
Yasufumi Ueda
Koji Matsuda
Mikio Kabaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE69615570D1 publication Critical patent/DE69615570D1/de
Publication of DE69615570T2 publication Critical patent/DE69615570T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/18—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69615570T 1995-08-07 1996-07-25 Verfahren zur herstellung von carbamoylmethylharnstoff-derivaten Expired - Fee Related DE69615570T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20074995 1995-08-07
PCT/JP1996/002078 WO1997006135A1 (fr) 1995-08-07 1996-07-25 Procede de preparation de derives de carbamoylmethyluree

Publications (2)

Publication Number Publication Date
DE69615570D1 DE69615570D1 (de) 2001-10-31
DE69615570T2 true DE69615570T2 (de) 2002-07-11

Family

ID=16429540

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69615570T Expired - Fee Related DE69615570T2 (de) 1995-08-07 1996-07-25 Verfahren zur herstellung von carbamoylmethylharnstoff-derivaten

Country Status (12)

Country Link
US (1) US6015921A (de)
EP (1) EP0844236B1 (de)
KR (1) KR19990036236A (de)
CN (1) CN1197451A (de)
AT (1) ATE206109T1 (de)
AU (1) AU6530796A (de)
CA (1) CA2228622A1 (de)
DE (1) DE69615570T2 (de)
ES (1) ES2164258T3 (de)
PT (1) PT844236E (de)
TW (1) TW358087B (de)
WO (1) WO1997006135A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5647790B2 (ja) * 2007-11-16 2015-01-07 株式会社カネカ Ｎ−カルバモイル−ｔｅｒｔ−ロイシンの製造法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2928873A (en) * 1959-01-07 1960-03-15 U S Vitamin And Pharmaceutical Certain monoamides of hydantoic acid
US5382590A (en) * 1990-02-09 1995-01-17 Rhone-Poulenc Rorer S.A. N-phenyl-N-acetamidoglycinamides, their preparation and medicaments containing them
FR2667864B2 (fr) * 1990-03-07 1994-08-05 Rhone Poulenc Sante Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
FR2659653B1 (fr) * 1990-03-13 1992-05-22 Rhone Poulenc Sante Derives de l'uree, leur preparation et les medicaments les contenant.
JP2877475B2 (ja) * 1990-09-10 1999-03-31 協和醗酵工業株式会社 ジチオールイリデン誘導体
AU691565B2 (en) * 1994-02-09 1998-05-21 Shionogi & Co., Ltd. Carbamoylmethylurea derivative

Also Published As

Publication number Publication date
PT844236E (pt) 2002-01-30
ATE206109T1 (de) 2001-10-15
CN1197451A (zh) 1998-10-28
EP0844236B1 (de) 2001-09-26
CA2228622A1 (en) 1997-02-20
ES2164258T3 (es) 2002-02-16
AU6530796A (en) 1997-03-05
DE69615570D1 (de) 2001-10-31
EP0844236A4 (de) 1999-04-14
WO1997006135A1 (fr) 1997-02-20
KR19990036236A (ko) 1999-05-25
TW358087B (en) 1999-05-11
US6015921A (en) 2000-01-18
EP0844236A1 (de) 1998-05-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee