DE60314623D1 - Substituierte pyrazolopyrimidine - Google Patents

Substituierte pyrazolopyrimidine

Info

Publication number: DE60314623D1
Authority: DE; Germany
Prior art keywords: substituted pyrazolopyrimidines; same; pyrazolopyrimidines; substituted; preparing
Prior art date: 2002-05-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60314623T

Other languages

English (en)

Other versions

DE60314623T2 (de

Inventor

Kristjan S Gudmundsson

Brian A Johns

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-10

Filing date

2003-04-30

Publication date

2007-08-09

2003-04-30 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

2007-08-09 Application granted granted Critical

2007-08-09 Publication of DE60314623D1 publication Critical patent/DE60314623D1/de

2008-02-28 Publication of DE60314623T2 publication Critical patent/DE60314623T2/de

2023-05-01 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

DE60314623T 2002-05-10 2003-04-30 Substituierte pyrazolopyrimidine Expired - Fee Related DE60314623T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US37942102P	2002-05-10	2002-05-10
US379421P		2002-05-10
PCT/US2003/013395 WO2003095455A2 (en)	2002-05-10	2003-04-30	Substituted pyrazolopyrimidines

Publications (2)

Publication Number	Publication Date
DE60314623D1 true DE60314623D1 (de)	2007-08-09
DE60314623T2 DE60314623T2 (de)	2008-02-28

Family

ID=29420528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60314623T Expired - Fee Related DE60314623T2 (de)	2002-05-10	2003-04-30	Substituierte pyrazolopyrimidine

Country Status (8)

Country	Link
US (1)	US7304068B2 (de)
EP (1)	EP1504004B1 (de)
JP (1)	JP2005529919A (de)
AT (1)	ATE365740T1 (de)
AU (1)	AU2003228770A1 (de)
DE (1)	DE60314623T2 (de)
ES (1)	ES2287476T3 (de)
WO (1)	WO2003095455A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003217712A1 (en)	2002-03-07	2003-09-22	Smithkline Beecham Corporation	Pyrazolopyrimidine and pyrazolotriazine derivatives and pharmaceutical compositions containing them
US7196078B2 (en)	2002-09-04	2007-03-27	Schering Corpoartion	Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7129239B2 (en)	2002-10-28	2006-10-31	Pfizer Inc.	Purine compounds and uses thereof
US7247628B2 (en)	2002-12-12	2007-07-24	Pfizer, Inc.	Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) *	2003-02-10	2007-02-13	Pfizer Inc.	Cannabinoid receptor ligands and uses thereof
US7141669B2 (en)	2003-04-23	2006-11-28	Pfizer Inc.	Cannabiniod receptor ligands and uses thereof
US7268133B2 (en)	2003-04-23	2007-09-11	Pfizer, Inc. Patent Department	Cannabinoid receptor ligands and uses thereof
US7145012B2 (en)	2003-04-23	2006-12-05	Pfizer Inc.	Cannabinoid receptor ligands and uses thereof
US7232823B2 (en)	2003-06-09	2007-06-19	Pfizer, Inc.	Cannabinoid receptor ligands and uses thereof
FR2859729B1 (fr) *	2003-09-12	2006-02-24	Roquette Freres	Dispersions aqueuses d'au moins un polymere biodegradable
TW200639163A (en)	2005-02-04	2006-11-16	Genentech Inc	RAF inhibitor compounds and methods
UA103319C2 (en)	2008-05-06	2013-10-10	Глаксосмитклайн Ллк	Thiazole- and oxazole-benzene sulfonamide compounds
EP2308866A1 (de)	2009-10-09	2011-04-13	Bayer CropScience AG	Phenylpyri(mi)dinylpyrazole und ihre Verwendung als Fungizide
CN102762551A (zh)	2009-12-21	2012-10-31	拜尔农作物科学股份公司	噻吩基吡(嘧)啶基吡唑及其用于防治植物致病菌的用途
AR081810A1 (es)	2010-04-07	2012-10-24	Bayer Cropscience Ag	Piridinilpirazoles biciclicos
EP2585467B1 (de) *	2010-06-24	2016-03-02	Gilead Sciences, Inc.	Pyrazolo[1,5-a]pyrimidine und -triazine als antivirale agentien
AU2015200638B2 (en) *	2010-06-24	2016-11-10	Gilead Sciences, Inc.	Pyrazolo [1, 5 -a] pyrimidines as antiviral agents
EP2402344A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazolkondensierte bicyclische Verbindungen
EP2402343A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazole kondensierte bizyclische Verbindungen
EP2402345A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazole kondensierte bizyclische Verbindungen
EP2402337A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazolopyridin-Verbindungen
AR086992A1 (es)	2011-06-20	2014-02-05	Bayer Ip Gmbh	Tienilpiri(mi)dinilpirazoles
US8633198B1 (en) *	2011-09-20	2014-01-21	Nant Holdings Ip, Llc	Small molecule inhibitors of influenza A RNA-dependent RNA polymerase
AU2012320581B2 (en)	2011-10-06	2017-03-30	Bayer Intellectual Property Gmbh	Heterocyclylpyri (mi) dinylpyrazole as fungicidals
DK2763993T3 (en)	2011-10-06	2017-07-24	Bayer Ip Gmbh	HETEROCYCLYLPYRI (MI) DINYLPYRAZOL
WO2013096681A1 (en) *	2011-12-22	2013-06-27	Gilead Sciences, Inc.	Pyrazolo[1,5-a]pyrimidines as antiviral agents
CN106986869A (zh)	2012-04-17	2017-07-28	吉利德科学公司	用于抗病毒治疗的化合物和方法
KR101868128B1 (ko) *	2013-12-11	2018-06-18	난트 홀딩스 아이피, 엘엘씨	인플루엔자 a rna-의존성 rna 폴리머라제의 저분자 저해제
EP3087069B1 (de)	2013-12-23	2019-01-30	Norgine B.V.	Als ccr9-modulatoren verwendbare verbindungen
CN106061975B (zh) *	2014-01-22	2019-09-24	库洛维公司	作为抗病毒化合物的吡唑并[1,5-a]嘧啶
US9981976B2 (en) *	2014-12-08	2018-05-29	Janssen Sciences Ireland Uc	Piperidine substituted pyrazolo[1,5-A]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV)
AU2019370200A1 (en)	2018-10-30	2021-06-10	Kronos Bio, Inc.	Compounds, compositions, and methods for modulating CDK9 activity
EP4262792A1 (de) *	2020-12-18	2023-10-25	The Scripps Research Institute	Verbindungen und ihre verwendung zur behandlung von neurodegenerativen, degenerativen und metabolischen erkrankungen

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5356897A (en) *	1991-09-09	1994-10-18	Fujisawa Pharmaceutical Co., Ltd.	3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
JPH11505524A (ja)	1995-05-01	1999-05-21	藤沢薬品工業株式会社	イミダゾ１，２−ａピリジンおよびイミダゾ１，２−ａピリデジン誘導体、および骨吸収阻害剤としてのその用途
US6313124B1 (en) *	1997-07-23	2001-11-06	Dupont Pharmaceuticals Company	Tetrazine bicyclic compounds
US6060478A (en) *	1996-07-24	2000-05-09	Dupont Pharmaceuticals	Azolo triazines and pyrimidines
US6191131B1 (en) *	1997-07-23	2001-02-20	Dupont Pharmaceuticals Company	Azolo triazines and pyrimidines
US6124289A (en) *	1996-07-24	2000-09-26	Dupont Pharmaceuticals Co.	Azolo triazines and pyrimidines
CA2288741A1 (en) *	1997-05-22	1998-11-26	G.D. Searle And Co.	4-aryl-3(5)-heteroaryl substituted pyrazoles as p38 kinase inhibitors
CA2291709A1 (en)	1997-05-30	1998-12-03	Merck & Co., Inc.	Novel angiogenesis inhibitors
JP2000038350A (ja)	1998-05-18	2000-02-08	Yoshitomi Pharmaceut Ind Ltd	糖尿病治療薬
US6770666B2 (en) *	1999-12-27	2004-08-03	Japan Tobacco Inc.	Fused-ring compounds and use thereof as drugs
PE20020506A1 (es)	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
GB0103926D0 (en)	2001-02-17	2001-04-04	Astrazeneca Ab	Chemical compounds

2003
- 2003-04-30 JP JP2004503469A patent/JP2005529919A/ja active Pending
- 2003-04-30 WO PCT/US2003/013395 patent/WO2003095455A2/en active IP Right Grant
- 2003-04-30 US US10/512,916 patent/US7304068B2/en not_active Expired - Fee Related
- 2003-04-30 AU AU2003228770A patent/AU2003228770A1/en not_active Abandoned
- 2003-04-30 ES ES03726540T patent/ES2287476T3/es not_active Expired - Lifetime
- 2003-04-30 AT AT03726540T patent/ATE365740T1/de not_active IP Right Cessation
- 2003-04-30 EP EP03726540A patent/EP1504004B1/de not_active Expired - Lifetime
- 2003-04-30 DE DE60314623T patent/DE60314623T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US7304068B2 (en)	2007-12-04
AU2003228770A8 (en)	2003-11-11
JP2005529919A (ja)	2005-10-06
WO2003095455A3 (en)	2003-12-24
WO2003095455A2 (en)	2003-11-20
ES2287476T3 (es)	2007-12-16
EP1504004A2 (de)	2005-02-09
ATE365740T1 (de)	2007-07-15
AU2003228770A1 (en)	2003-11-11
EP1504004B1 (de)	2007-06-27
DE60314623T2 (de)	2008-02-28
US20050203106A1 (en)	2005-09-15

Legal Events

Date

Code

Title

Description

2008-01-31

8381

Inventor (new situation)

Inventor name: GUDMUNDSSON, KRISTJAN S., RESEARCH TRIANGLE PA, US

Inventor name: JOHNS, BRIAN A., RESEARCH TRIANGLE PARK, NC 27, US

2008-07-17

8364

No opposition during term of opposition

2010-02-18

8339

Ceased/non-payment of the annual fee

Publication	Publication Date	Title
ATE365740T1 (de)	2007-07-15	Substituierte pyrazolopyrimidine
ATE433447T1 (de)	2009-06-15	Pyrimiidinverbindungen
DE60212949D1 (de)	2006-08-17	Antivirale pyrazolopyridin verbindungen
ATE301653T1 (de)	2005-08-15	Pyrazolopyridine
ATE296826T1 (de)	2005-06-15	Pyrazolo(1,5)pyridinderivate
SE0301700D0 (sv)	2003-06-10	Novel compounds
ATE430747T1 (de)	2009-05-15	2-pyrimidinyl-pyrazolopyridin-erbb- kinaseinhibitoren
NO20050525L (no)	2005-05-06	Benzimidazol-1-yl-tiofenforbindelser for behandling av cancer
SE0302811D0 (sv)	2003-10-23	Novel compounds
SE0200920D0 (sv)	2002-03-25	Novel compounds
SE0202539D0 (sv)	2002-08-27	Compounds
SE0202133D0 (sv)	2002-07-08	Novel compounds
IS6658A (is)	2002-12-17	Ný efnasambönd
ATE300541T1 (de)	2005-08-15	Pyrazolopyridinderivate
SE0302139D0 (sv)	2003-07-28	Novel compounds
ATE302203T1 (de)	2005-09-15	Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen
DE60220525D1 (de)	2007-07-19	Pyrazolo-pyridine für die behandlung von herpes-ansteckungen
MXPA05012247A (es)	2006-02-10	Derivados de bencimidazol nuevos.
SE0303541D0 (sv)	2003-12-22	New compounds
SE0102716D0 (sv)	2001-08-14	Novel compounds
SE0303280D0 (sv)	2003-12-05	Novel compounds
ATE274515T1 (de)	2004-09-15	Pyrazolopyridinderivate
DE69911785D1 (de)	2003-11-06	Triazolo[4,5-d]pyrimidin-verbindungen
ATE373000T1 (de)	2007-09-15	Pyrazolopyridin-derivate als antiherpesmittel
SE0302755D0 (sv)	2003-10-17	Novel compounds