DE60304599D1 - Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number: DE60304599D1
Authority: DE; Germany
Prior art keywords: production; pharmaceutical compositions; compositions containing; pyridopyrimidinone derivatives; pyridopyrimidinone
Prior art date: 2002-11-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60304599T

Other languages

English (en)

Other versions

DE60304599T2 (de

Inventor

Sylvain Rault

Jean-Charles Lancelot

Marina Kopp

Daniel-Henri Caignard

Buno Pfeiffer

Pierre Renard

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratoires Servier SAS

Original Assignee

Laboratoires Servier SAS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-05

Filing date

2003-11-04

Publication date

2006-05-24

2003-11-04 Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS

2006-05-24 Publication of DE60304599D1 publication Critical patent/DE60304599D1/de

2007-05-16 Application granted granted Critical

2007-05-16 Publication of DE60304599T2 publication Critical patent/DE60304599T2/de

2023-11-05 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

DE60304599T 2002-11-05 2003-11-04 Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen Expired - Fee Related DE60304599T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0213804A FR2846657B1 (fr)	2002-11-05	2002-11-05	Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR0213804		2002-11-05
PCT/FR2003/003274 WO2004043956A1 (fr)	2002-11-05	2003-11-04	Composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number	Publication Date
DE60304599D1 true DE60304599D1 (de)	2006-05-24
DE60304599T2 DE60304599T2 (de)	2007-05-16

Family

ID=32104442

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60304599T Expired - Fee Related DE60304599T2 (de)	2002-11-05	2003-11-04	Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (28)

Country	Link
US (1)	US7361662B2 (de)
EP (1)	EP1560826B1 (de)
JP (1)	JP2006512317A (de)
KR (1)	KR100717489B1 (de)
CN (1)	CN1330650C (de)
AR (1)	AR041883A1 (de)
AT (1)	ATE323092T1 (de)
AU (1)	AU2003292320B2 (de)
BR (1)	BR0315801A (de)
CA (1)	CA2503995A1 (de)
CY (1)	CY1105047T1 (de)
DE (1)	DE60304599T2 (de)
DK (1)	DK1560826T3 (de)
EA (1)	EA009043B1 (de)
ES (1)	ES2261978T3 (de)
FR (1)	FR2846657B1 (de)
GE (1)	GEP20084376B (de)
HK (1)	HK1081965A1 (de)
MA (1)	MA27410A1 (de)
MX (1)	MXPA05004789A (de)
MY (1)	MY140164A (de)
NO (1)	NO20052683D0 (de)
NZ (1)	NZ539598A (de)
PL (1)	PL376399A1 (de)
PT (1)	PT1560826E (de)
UA (1)	UA80578C2 (de)
WO (1)	WO2004043956A1 (de)
ZA (1)	ZA200503233B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2007303846B2 (en) *	2006-10-04	2011-03-10	Pfizer Products Inc.	Pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as calcium receptor antagonists
CN101531638B (zh) *	2008-03-13	2011-12-28	中国科学院广州生物医药与健康研究院	用作***相关受体调节剂的化合物及其应用
CN101619063B (zh) *	2009-06-02	2011-08-10	华中师范大学	具有抗肿瘤活性的3,7,8-多取代吡啶并[4,3-d]嘧啶衍生物及制备
US8981087B2 (en)	2009-07-29	2015-03-17	Karus Therapeutics Limited	Benzo [E] [1,3] oxazin-4-one derivatives as phosphoinositide 3-kinase inhibitors
PL2467387T3 (pl)	2009-08-20	2015-08-31	Karus Therapeutics Ltd	Tricykliczne związki heterocykliczne jako inhibitory kinazy 3-fosfoinozytydu
GB201204125D0 (en)	2012-03-08	2012-04-25	Karus Therapeutics Ltd	Compounds
EA030253B1 (ru)	2012-09-28	2018-07-31	Кэнсэр Ресерч Текнолоджи Лимитед	Азахиназолиновые ингибиторы атипичной протеинкиназы c
GB201402431D0 (en)	2014-02-12	2014-03-26	Karus Therapeutics Ltd	Compounds
WO2016068580A2 (en)	2014-10-29	2016-05-06	Dong-A Socio Holdings Co., Ltd.	Novel pyridopyrimidinone compounds for modulating the catalytic activity of histone lysine demethylases (kdms)
GB201514751D0 (en)	2015-08-19	2015-09-30	Karus Therapeutics Ltd	Compounds
GB201514754D0 (en)	2015-08-19	2015-09-30	Karus Therapeutics Ltd	Compounds
GB201514760D0 (en)	2015-08-19	2015-09-30	Karus Therapeutics Ltd	Compounds and method of use
GB201514758D0 (en)	2015-08-19	2015-09-30	Karus Therapeutics Ltd	Formulation
US20170057955A1 (en) *	2015-08-26	2017-03-02	Dong-A Socio Holdings Co., Ltd.	Pyridopyrimidinone Compounds for Modulating the Catalytic Activity of Histone Lysine Demethylases (KDMs)
CN105616420A (zh) *	2016-01-16	2016-06-01	赵国良	一种降血脂的药物组合物
IL277071B1 (en)	2018-03-08	2024-03-01	Incyte Corp	Aminopyrizine diol compounds as PI3K–y inhibitors
US11046658B2 (en)	2018-07-02	2021-06-29	Incyte Corporation	Aminopyrazine derivatives as PI3K-γ inhibitors
WO2021102288A1 (en) *	2019-11-22	2021-05-27	Senda Biosciences, Inc.	Pyridopyrimidinone derivatives as ahr antagonists
WO2024008722A2 (en) *	2022-07-04	2024-01-11	Muna Therapeutics Aps	Trem2 modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6348310B1 (en) *	1994-03-04	2002-02-19	Promega Corporation	Quantitation of individual protein kinase activity
US6060477A (en) *	1995-06-07	2000-05-09	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives
ZA9756B (en) *	1996-01-16	1997-07-17	Warner Lambert Co	Process for preparing 4,6-disubstituted pyrido[3,4-d]-pyrimidines
HRP970371A2 (en) *	1996-07-13	1998-08-31	Kathryn Jane Smith	Heterocyclic compounds
KR20000029843A (ko) *	1996-08-06	2000-05-25	디. 제이. 우드;스피겔 알렌 제이	치환된피리도-또는피리미도-함유6,6-또는6,7-비시클릭유도체
US6962922B2 (en) *	2001-10-12	2005-11-08	Warner-Lambert Company Llc	Alkynylated quinazoline compounds
AUPS019702A0 (en) *	2002-01-29	2002-02-21	Fujisawa Pharmaceutical Co., Ltd.	Condensed heterocyclic compounds

2002
- 2002-11-05 FR FR0213804A patent/FR2846657B1/fr not_active Expired - Fee Related
2003
- 2003-04-11 UA UAA200505315A patent/UA80578C2/uk unknown
- 2003-10-09 MY MYPI20033854A patent/MY140164A/en unknown
- 2003-11-04 JP JP2004550726A patent/JP2006512317A/ja active Pending
- 2003-11-04 AR ARP030104026A patent/AR041883A1/es unknown
- 2003-11-04 US US10/533,697 patent/US7361662B2/en not_active Expired - Fee Related
- 2003-11-04 CA CA002503995A patent/CA2503995A1/fr not_active Abandoned
- 2003-11-04 WO PCT/FR2003/003274 patent/WO2004043956A1/fr active IP Right Grant
- 2003-11-04 EA EA200500690A patent/EA009043B1/ru not_active IP Right Cessation
- 2003-11-04 BR BR0315801-2A patent/BR0315801A/pt not_active IP Right Cessation
- 2003-11-04 MX MXPA05004789A patent/MXPA05004789A/es active IP Right Grant
- 2003-11-04 ES ES03767886T patent/ES2261978T3/es not_active Expired - Lifetime
- 2003-11-04 AU AU2003292320A patent/AU2003292320B2/en not_active Expired - Fee Related
- 2003-11-04 KR KR1020057007994A patent/KR100717489B1/ko not_active IP Right Cessation
- 2003-11-04 DK DK03767886T patent/DK1560826T3/da active
- 2003-11-04 EP EP03767886A patent/EP1560826B1/de not_active Expired - Lifetime
- 2003-11-04 PL PL03376399A patent/PL376399A1/xx not_active Application Discontinuation
- 2003-11-04 GE GEAP20038824A patent/GEP20084376B/en unknown
- 2003-11-04 CN CNB2003801027139A patent/CN1330650C/zh not_active Expired - Fee Related
- 2003-11-04 PT PT03767886T patent/PT1560826E/pt unknown
- 2003-11-04 NZ NZ539598A patent/NZ539598A/en unknown
- 2003-11-04 DE DE60304599T patent/DE60304599T2/de not_active Expired - Fee Related
- 2003-11-04 AT AT03767886T patent/ATE323092T1/de not_active IP Right Cessation
2005
- 2005-04-19 MA MA28232A patent/MA27410A1/fr unknown
- 2005-04-21 ZA ZA200503233A patent/ZA200503233B/en unknown
- 2005-06-03 NO NO20052683A patent/NO20052683D0/no not_active Application Discontinuation
2006
- 2006-02-22 HK HK06102331A patent/HK1081965A1/xx not_active IP Right Cessation
- 2006-06-08 CY CY20061100767T patent/CY1105047T1/el unknown

Also Published As

Publication number	Publication date
EP1560826A1 (de)	2005-08-10
KR20050087792A (ko)	2005-08-31
EA200500690A1 (ru)	2005-10-27
MA27410A1 (fr)	2005-06-01
US7361662B2 (en)	2008-04-22
CN1711260A (zh)	2005-12-21
EA009043B1 (ru)	2007-10-26
FR2846657A1 (fr)	2004-05-07
ATE323092T1 (de)	2006-04-15
PT1560826E (pt)	2006-07-31
CY1105047T1 (el)	2009-11-04
EP1560826B1 (de)	2006-04-12
NZ539598A (en)	2006-11-30
HK1081965A1 (en)	2006-05-26
DK1560826T3 (da)	2006-08-14
UA80578C2 (en)	2007-10-10
US20050288311A1 (en)	2005-12-29
BR0315801A (pt)	2005-09-20
WO2004043956A8 (fr)	2005-06-09
KR100717489B1 (ko)	2007-05-14
ZA200503233B (en)	2006-06-28
PL376399A1 (en)	2005-12-27
WO2004043956A1 (fr)	2004-05-27
NO20052683L (no)	2005-06-03
AR041883A1 (es)	2005-06-01
MXPA05004789A (es)	2005-07-22
ES2261978T3 (es)	2006-11-16
FR2846657B1 (fr)	2004-12-24
AU2003292320B2 (en)	2009-03-12
JP2006512317A (ja)	2006-04-13
GEP20084376B (en)	2008-05-27
MY140164A (en)	2009-11-30
AU2003292320A1 (en)	2004-06-03
CN1330650C (zh)	2007-08-08
NO20052683D0 (no)	2005-06-03
CA2503995A1 (fr)	2004-05-27
DE60304599T2 (de)	2007-05-16

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Legal Events

Date	Code	Title	Description
2007-05-03	8364	No opposition during term of opposition
2010-09-16	8339	Ceased/non-payment of the annual fee