DE60219810D1 - Universelles, durch licht einschaltbares genpromotorsystem - Google Patents
Universelles, durch licht einschaltbares genpromotorsystemInfo
- Publication number
- DE60219810D1 DE60219810D1 DE60219810T DE60219810T DE60219810D1 DE 60219810 D1 DE60219810 D1 DE 60219810D1 DE 60219810 T DE60219810 T DE 60219810T DE 60219810 T DE60219810 T DE 60219810T DE 60219810 D1 DE60219810 D1 DE 60219810D1
- Authority
- DE
- Germany
- Prior art keywords
- phytochrome
- light
- promoter
- universal
- activation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Air-Conditioning For Vehicles (AREA)
- Lighting Device Outwards From Vehicle And Optical Signal (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31461501P | 2001-08-23 | 2001-08-23 | |
US35540202P | 2002-02-06 | 2002-02-06 | |
PCT/US2002/027216 WO2003018777A1 (en) | 2001-08-23 | 2002-08-23 | A universal light-switchable gene promoter system |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60219810D1 true DE60219810D1 (de) | 2007-06-06 |
Family
ID=26979455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60219810T Expired - Lifetime DE60219810D1 (de) | 2001-08-23 | 2002-08-23 | Universelles, durch licht einschaltbares genpromotorsystem |
Country Status (6)
Country | Link |
---|---|
US (1) | US6858429B2 (de) |
EP (1) | EP1434852B1 (de) |
AT (1) | ATE360680T1 (de) |
CA (1) | CA2458224A1 (de) |
DE (1) | DE60219810D1 (de) |
WO (1) | WO2003018777A1 (de) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030049799A1 (en) * | 2000-10-23 | 2003-03-13 | Schwartz John Jacob | Engineered stimulus-responsive switches |
US7795397B2 (en) * | 2004-05-06 | 2010-09-14 | The Regents Of The University Of California | Red and near infrared flourescent phyotochrome |
US20070053996A1 (en) | 2005-07-22 | 2007-03-08 | Boyden Edward S | Light-activated cation channel and uses thereof |
US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
US20070136897A1 (en) * | 2005-10-12 | 2007-06-14 | Kim Jeong-Ii | Nucleic acid molecules encoding hyperactive nucleoside di-phosphate kinase 2 and uses thereof |
US7613574B2 (en) * | 2005-10-28 | 2009-11-03 | S-Matrix | System and method for automating scientific and engineering experimentation for deriving surrogate response data |
WO2007120989A2 (en) * | 2006-02-24 | 2007-10-25 | Ceres, Inc. | Shade regulatory regions |
WO2008067089A2 (en) * | 2006-10-27 | 2008-06-05 | Indiana University Research & Technology Corporation | Light-regulated transcription system for use in prokaryotic organisms |
US8398692B2 (en) | 2007-01-10 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
DE102007003577A1 (de) | 2007-01-24 | 2008-08-07 | Julius-Maximilians-Universität Würzburg | Zwei-Komponentensystem zur Programmierung bakterieller Membranen |
WO2008106694A2 (en) | 2007-03-01 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
US8480662B2 (en) * | 2007-08-22 | 2013-07-09 | Cardiac Pacemakers, Inc. | Systems and devices for photoablation |
US20090054828A1 (en) * | 2007-08-22 | 2009-02-26 | Cardiac Pacemakers, Inc. | Systems for transient conduction control |
US10035027B2 (en) | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
RU2010147661A (ru) | 2008-04-23 | 2012-05-27 | Дзе Борд Оф Трастиз Оф Дзе Лелэнд Стэнфорд Джуниор Юниверсити (Us) | Системы, способы и композиции для оптической стимуляции клеток-мишеней |
WO2009151948A2 (en) * | 2008-05-23 | 2009-12-17 | The Regents Of The University Of California | Spatio-temporal control of protein interactions using phytochromes |
US10711242B2 (en) | 2008-06-17 | 2020-07-14 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and methods for controlling cellular development |
ES2475973T3 (es) | 2008-06-27 | 2014-07-11 | Sapphire Energy, Inc. | Inducción de la floculaci�n en organismos fotosint�ticos |
WO2010006049A1 (en) | 2008-07-08 | 2010-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
US8419145B2 (en) * | 2008-07-25 | 2013-04-16 | Eastman Kodak Company | Inkjet printhead and method of printing with multiple drop volumes |
NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
WO2011130540A1 (en) * | 2010-04-14 | 2011-10-20 | Duke University | Light stimulated protein interaction molecules and methods of use |
EP2635108B1 (de) | 2010-11-05 | 2019-01-23 | The Board of Trustees of the Leland Stanford Junior University | Lichtaktivierte chimäre opsine und verwendungsverfahren dafür |
JP6328424B6 (ja) | 2010-11-05 | 2018-07-11 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 記憶機能の制御および特性化 |
CN110215614A (zh) | 2010-11-05 | 2019-09-10 | 斯坦福大学托管董事会 | 用于光遗传学方法的光的上转换 |
CA2816968C (en) | 2010-11-05 | 2019-11-26 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-controlled cns dysfunction |
CN105941328B (zh) | 2010-11-05 | 2019-04-09 | 斯坦福大学托管董事会 | 一种鉴定抑制前额叶皮质中的兴奋性或抑制性神经元的去极化的化合物的*** |
EP2635346B1 (de) | 2010-11-05 | 2017-03-29 | The Board of Trustees of the Leland Stanford Junior University | Optogenetische steuerung eines verhaltens in zusammenhang mit belohnungen |
US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
CN102643852B (zh) | 2011-02-28 | 2015-04-08 | 华东理工大学 | 光可控的基因表达*** |
US10041057B2 (en) | 2011-07-27 | 2018-08-07 | University Of Wyoming | Near-infrared light-activated proteins |
WO2013016693A2 (en) | 2011-07-27 | 2013-01-31 | University Of Wyoming | Near-infrared light-activated proteins |
CN104093833B (zh) | 2011-12-16 | 2017-11-07 | 斯坦福大学托管董事会 | 视蛋白多肽及其使用方法 |
EP2817068B1 (de) | 2012-02-21 | 2017-04-12 | The Board of Trustees of the Leland Stanford Junior University | Zusammensetzungen zur behandlung neurogener erkrankungen des beckenbodens |
EP2674497A1 (de) * | 2012-06-12 | 2013-12-18 | Baden-Württemberg Stiftung gGmbH | Lichtreguliertes transgenes Expressionssystem |
CN103031327B (zh) * | 2012-08-02 | 2015-11-25 | 华东理工大学 | 原核细菌光诱导基因表达***及其调控基因表达的方法 |
WO2014121806A1 (en) * | 2013-02-08 | 2014-08-14 | Baden-Württemberg Stiftung Gmbh | System for the caging and controlled release of proteins |
EP2968997B1 (de) | 2013-03-15 | 2019-06-26 | The Board of Trustees of the Leland Stanford Junior University | Optogenetische steuerung des verhaltenszustandes |
WO2014179331A2 (en) * | 2013-04-29 | 2014-11-06 | The Board Of Trustees Of The Leland Stanford Junior University | Devices, systems and methods for optogenetic modulation of action potentials in target cells |
AU2014306679A1 (en) | 2013-08-14 | 2016-03-10 | Circuit Therapeutics, Inc. | Compositions and methods for controlling pain |
US10702581B2 (en) | 2015-05-04 | 2020-07-07 | Ilias Biologics Inc. | Compositions containing protein loaded exosome and methods for preparing and delivering the same |
KR20160130937A (ko) * | 2015-05-04 | 2016-11-15 | 한국과학기술원 | 목적 단백질을 포함하는 엑소솜의 제조 방법 및 상기 제조 방법에 의해 제조된 엑소솜을 이용하여 목적 단백질을 세포질로 전달시키는 방법 |
WO2016209654A1 (en) | 2015-06-22 | 2016-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
KR101751917B1 (ko) * | 2016-02-02 | 2017-06-28 | 기초과학연구원 | 가역적으로 활성화 가능한 항체 유사체 및 그의 용도 |
CN107177629A (zh) * | 2016-03-10 | 2017-09-19 | 华东师范大学 | 一种基因环路远程调控***进行转基因调控表达的方法 |
WO2017177147A1 (en) | 2016-04-07 | 2017-10-12 | Avalos Jose L | System and method of optogenetically controlling metabolic pathways for the production of chemicals |
US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
US20220244184A1 (en) * | 2019-05-14 | 2022-08-04 | The Regents Of The University Of California | Illumination Device for Spatial and Temporal Control of Morphogen Signaling in Cell Cultures |
CN112899157A (zh) * | 2020-12-28 | 2021-06-04 | 中国科学院长春应用化学研究所 | 微流控芯片光刺激装置和酵母单细胞光调控基因表达方法及应用 |
WO2022261075A1 (en) | 2021-06-07 | 2022-12-15 | The Board Of Trustees Of The University Of Illinois | Photoactivatable gasdermin proteins |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5639952A (en) * | 1989-01-05 | 1997-06-17 | Mycogen Plant Science, Inc. | Dark and light regulated chlorophyll A/B binding protein promoter-regulatory system |
US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
JP2003524368A (ja) * | 1997-08-26 | 2003-08-19 | アリアド ジーン セラピューティクス インコーポレイテッド | ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、dna結合ドメインまたはリガンド結合ドメインを含む融合蛋白 |
US6251676B1 (en) * | 2000-03-24 | 2001-06-26 | The General Hospital Corporation | Mammalian cell two-hybrid system |
-
2002
- 2002-08-23 DE DE60219810T patent/DE60219810D1/de not_active Expired - Lifetime
- 2002-08-23 CA CA002458224A patent/CA2458224A1/en not_active Abandoned
- 2002-08-23 EP EP02757404A patent/EP1434852B1/de not_active Expired - Lifetime
- 2002-08-23 WO PCT/US2002/027216 patent/WO2003018777A1/en active IP Right Grant
- 2002-08-23 US US10/227,035 patent/US6858429B2/en not_active Expired - Lifetime
- 2002-08-23 AT AT02757404T patent/ATE360680T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20030082809A1 (en) | 2003-05-01 |
WO2003018777A1 (en) | 2003-03-06 |
EP1434852A1 (de) | 2004-07-07 |
EP1434852A4 (de) | 2004-12-22 |
ATE360680T1 (de) | 2007-05-15 |
US6858429B2 (en) | 2005-02-22 |
EP1434852B1 (de) | 2007-04-25 |
CA2458224A1 (en) | 2003-03-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |