DE60219810D1 - Universelles, durch licht einschaltbares genpromotorsystem - Google Patents

Universelles, durch licht einschaltbares genpromotorsystem

Info

Publication number
DE60219810D1
DE60219810D1 DE60219810T DE60219810T DE60219810D1 DE 60219810 D1 DE60219810 D1 DE 60219810D1 DE 60219810 T DE60219810 T DE 60219810T DE 60219810 T DE60219810 T DE 60219810T DE 60219810 D1 DE60219810 D1 DE 60219810D1
Authority
DE
Germany
Prior art keywords
phytochrome
light
promoter
universal
activation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60219810T
Other languages
English (en)
Inventor
Peter H Quail
Enamul Huq
James Tepperman
Sae Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Application granted granted Critical
Publication of DE60219810D1 publication Critical patent/DE60219810D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237Externally regulated expression systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217Gene switch

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Air-Conditioning For Vehicles (AREA)
  • Lighting Device Outwards From Vehicle And Optical Signal (AREA)
  • Saccharide Compounds (AREA)
DE60219810T 2001-08-23 2002-08-23 Universelles, durch licht einschaltbares genpromotorsystem Expired - Lifetime DE60219810D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31461501P 2001-08-23 2001-08-23
US35540202P 2002-02-06 2002-02-06
PCT/US2002/027216 WO2003018777A1 (en) 2001-08-23 2002-08-23 A universal light-switchable gene promoter system

Publications (1)

Publication Number Publication Date
DE60219810D1 true DE60219810D1 (de) 2007-06-06

Family

ID=26979455

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60219810T Expired - Lifetime DE60219810D1 (de) 2001-08-23 2002-08-23 Universelles, durch licht einschaltbares genpromotorsystem

Country Status (6)

Country Link
US (1) US6858429B2 (de)
EP (1) EP1434852B1 (de)
AT (1) ATE360680T1 (de)
CA (1) CA2458224A1 (de)
DE (1) DE60219810D1 (de)
WO (1) WO2003018777A1 (de)

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US20030049799A1 (en) * 2000-10-23 2003-03-13 Schwartz John Jacob Engineered stimulus-responsive switches
US7795397B2 (en) * 2004-05-06 2010-09-14 The Regents Of The University Of California Red and near infrared flourescent phyotochrome
US20070053996A1 (en) 2005-07-22 2007-03-08 Boyden Edward S Light-activated cation channel and uses thereof
US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US8926959B2 (en) 2005-07-22 2015-01-06 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
US10052497B2 (en) 2005-07-22 2018-08-21 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US20070136897A1 (en) * 2005-10-12 2007-06-14 Kim Jeong-Ii Nucleic acid molecules encoding hyperactive nucleoside di-phosphate kinase 2 and uses thereof
US7613574B2 (en) * 2005-10-28 2009-11-03 S-Matrix System and method for automating scientific and engineering experimentation for deriving surrogate response data
WO2007120989A2 (en) * 2006-02-24 2007-10-25 Ceres, Inc. Shade regulatory regions
WO2008067089A2 (en) * 2006-10-27 2008-06-05 Indiana University Research & Technology Corporation Light-regulated transcription system for use in prokaryotic organisms
US8398692B2 (en) 2007-01-10 2013-03-19 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
DE102007003577A1 (de) 2007-01-24 2008-08-07 Julius-Maximilians-Universität Würzburg Zwei-Komponentensystem zur Programmierung bakterieller Membranen
WO2008106694A2 (en) 2007-03-01 2008-09-04 The Board Of Trustees Of The Leland Stanford Junior University Systems, methods and compositions for optical stimulation of target cells
US8480662B2 (en) * 2007-08-22 2013-07-09 Cardiac Pacemakers, Inc. Systems and devices for photoablation
US20090054828A1 (en) * 2007-08-22 2009-02-26 Cardiac Pacemakers, Inc. Systems for transient conduction control
US10035027B2 (en) 2007-10-31 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Device and method for ultrasonic neuromodulation via stereotactic frame based technique
US10434327B2 (en) 2007-10-31 2019-10-08 The Board Of Trustees Of The Leland Stanford Junior University Implantable optical stimulators
RU2010147661A (ru) 2008-04-23 2012-05-27 Дзе Борд Оф Трастиз Оф Дзе Лелэнд Стэнфорд Джуниор Юниверсити (Us) Системы, способы и композиции для оптической стимуляции клеток-мишеней
WO2009151948A2 (en) * 2008-05-23 2009-12-17 The Regents Of The University Of California Spatio-temporal control of protein interactions using phytochromes
US10711242B2 (en) 2008-06-17 2020-07-14 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and methods for controlling cellular development
ES2475973T3 (es) 2008-06-27 2014-07-11 Sapphire Energy, Inc. Inducción de la floculaci�n en organismos fotosint�ticos
WO2010006049A1 (en) 2008-07-08 2010-01-14 The Board Of Trustees Of The Leland Stanford Junior University Materials and approaches for optical stimulation of the peripheral nervous system
US8419145B2 (en) * 2008-07-25 2013-04-16 Eastman Kodak Company Inkjet printhead and method of printing with multiple drop volumes
NZ602416A (en) 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto
WO2011130540A1 (en) * 2010-04-14 2011-10-20 Duke University Light stimulated protein interaction molecules and methods of use
EP2635108B1 (de) 2010-11-05 2019-01-23 The Board of Trustees of the Leland Stanford Junior University Lichtaktivierte chimäre opsine und verwendungsverfahren dafür
JP6328424B6 (ja) 2010-11-05 2018-07-11 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 記憶機能の制御および特性化
CN110215614A (zh) 2010-11-05 2019-09-10 斯坦福大学托管董事会 用于光遗传学方法的光的上转换
CA2816968C (en) 2010-11-05 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Optically-controlled cns dysfunction
CN105941328B (zh) 2010-11-05 2019-04-09 斯坦福大学托管董事会 一种鉴定抑制前额叶皮质中的兴奋性或抑制性神经元的去极化的化合物的***
EP2635346B1 (de) 2010-11-05 2017-03-29 The Board of Trustees of the Leland Stanford Junior University Optogenetische steuerung eines verhaltens in zusammenhang mit belohnungen
US8696722B2 (en) 2010-11-22 2014-04-15 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic magnetic resonance imaging
CN102643852B (zh) 2011-02-28 2015-04-08 华东理工大学 光可控的基因表达***
US10041057B2 (en) 2011-07-27 2018-08-07 University Of Wyoming Near-infrared light-activated proteins
WO2013016693A2 (en) 2011-07-27 2013-01-31 University Of Wyoming Near-infrared light-activated proteins
CN104093833B (zh) 2011-12-16 2017-11-07 斯坦福大学托管董事会 视蛋白多肽及其使用方法
EP2817068B1 (de) 2012-02-21 2017-04-12 The Board of Trustees of the Leland Stanford Junior University Zusammensetzungen zur behandlung neurogener erkrankungen des beckenbodens
EP2674497A1 (de) * 2012-06-12 2013-12-18 Baden-Württemberg Stiftung gGmbH Lichtreguliertes transgenes Expressionssystem
CN103031327B (zh) * 2012-08-02 2015-11-25 华东理工大学 原核细菌光诱导基因表达***及其调控基因表达的方法
WO2014121806A1 (en) * 2013-02-08 2014-08-14 Baden-Württemberg Stiftung Gmbh System for the caging and controlled release of proteins
EP2968997B1 (de) 2013-03-15 2019-06-26 The Board of Trustees of the Leland Stanford Junior University Optogenetische steuerung des verhaltenszustandes
WO2014179331A2 (en) * 2013-04-29 2014-11-06 The Board Of Trustees Of The Leland Stanford Junior University Devices, systems and methods for optogenetic modulation of action potentials in target cells
AU2014306679A1 (en) 2013-08-14 2016-03-10 Circuit Therapeutics, Inc. Compositions and methods for controlling pain
US10702581B2 (en) 2015-05-04 2020-07-07 Ilias Biologics Inc. Compositions containing protein loaded exosome and methods for preparing and delivering the same
KR20160130937A (ko) * 2015-05-04 2016-11-15 한국과학기술원 목적 단백질을 포함하는 엑소솜의 제조 방법 및 상기 제조 방법에 의해 제조된 엑소솜을 이용하여 목적 단백질을 세포질로 전달시키는 방법
WO2016209654A1 (en) 2015-06-22 2016-12-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for imaging and/or optogenetic control of light-responsive neurons
KR101751917B1 (ko) * 2016-02-02 2017-06-28 기초과학연구원 가역적으로 활성화 가능한 항체 유사체 및 그의 용도
CN107177629A (zh) * 2016-03-10 2017-09-19 华东师范大学 一种基因环路远程调控***进行转基因调控表达的方法
WO2017177147A1 (en) 2016-04-07 2017-10-12 Avalos Jose L System and method of optogenetically controlling metabolic pathways for the production of chemicals
US11294165B2 (en) 2017-03-30 2022-04-05 The Board Of Trustees Of The Leland Stanford Junior University Modular, electro-optical device for increasing the imaging field of view using time-sequential capture
US20220244184A1 (en) * 2019-05-14 2022-08-04 The Regents Of The University Of California Illumination Device for Spatial and Temporal Control of Morphogen Signaling in Cell Cultures
CN112899157A (zh) * 2020-12-28 2021-06-04 中国科学院长春应用化学研究所 微流控芯片光刺激装置和酵母单细胞光调控基因表达方法及应用
WO2022261075A1 (en) 2021-06-07 2022-12-15 The Board Of Trustees Of The University Of Illinois Photoactivatable gasdermin proteins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639952A (en) * 1989-01-05 1997-06-17 Mycogen Plant Science, Inc. Dark and light regulated chlorophyll A/B binding protein promoter-regulatory system
US5283173A (en) 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
JP2003524368A (ja) * 1997-08-26 2003-08-19 アリアド ジーン セラピューティクス インコーポレイテッド ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、dna結合ドメインまたはリガンド結合ドメインを含む融合蛋白
US6251676B1 (en) * 2000-03-24 2001-06-26 The General Hospital Corporation Mammalian cell two-hybrid system

Also Published As

Publication number Publication date
US20030082809A1 (en) 2003-05-01
WO2003018777A1 (en) 2003-03-06
EP1434852A1 (de) 2004-07-07
EP1434852A4 (de) 2004-12-22
ATE360680T1 (de) 2007-05-15
US6858429B2 (en) 2005-02-22
EP1434852B1 (de) 2007-04-25
CA2458224A1 (en) 2003-03-06

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