DE60219429D1 - Biochemisches verfahren und vorrichtung zur bestimmung von eigenschaften von proteinen - Google Patents

Biochemisches verfahren und vorrichtung zur bestimmung von eigenschaften von proteinen

Info

Publication number
DE60219429D1
DE60219429D1 DE60219429T DE60219429T DE60219429D1 DE 60219429 D1 DE60219429 D1 DE 60219429D1 DE 60219429 T DE60219429 T DE 60219429T DE 60219429 T DE60219429 T DE 60219429T DE 60219429 D1 DE60219429 D1 DE 60219429D1
Authority
DE
Germany
Prior art keywords
supports
detecting
fluid
support
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60219429T
Other languages
English (en)
Other versions
DE60219429T2 (de
Inventor
Caroline Garey
Jodie Hadley
Mark England
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PRONOSTICS Ltd
Original Assignee
PRONOSTICS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0103473A external-priority patent/GB0103473D0/en
Priority claimed from GB0103464A external-priority patent/GB0103464D0/en
Priority claimed from GB0104125A external-priority patent/GB0104125D0/en
Application filed by PRONOSTICS Ltd filed Critical PRONOSTICS Ltd
Application granted granted Critical
Publication of DE60219429D1 publication Critical patent/DE60219429D1/de
Publication of DE60219429T2 publication Critical patent/DE60219429T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00502—Particles of irregular geometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00689—Automatic using computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00729—Peptide nucleic acids [PNA]
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60219429T 2001-02-13 2002-02-13 Biochemisches verfahren und vorrichtung zur bestimmung von eigenschaften von proteinen Expired - Lifetime DE60219429T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0103473A GB0103473D0 (en) 2001-02-13 2001-02-13 Micromachined coded labels used for proteomic bioassay methods
GB0103464A GB0103464D0 (en) 2001-02-13 2001-02-13 Micromachined coded labels used for a drug targetting biosassay method
GB0103473 2001-02-13
GB0103464 2001-02-13
GB0104125 2001-02-20
GB0104125A GB0104125D0 (en) 2001-02-20 2001-02-20 Micromachined coded labels used for the analysis of analytes associated with disease
PCT/GB2002/000628 WO2002065123A2 (en) 2001-02-13 2002-02-13 Biochemical method and apparatus for detecting protein characteristics

Publications (2)

Publication Number Publication Date
DE60219429D1 true DE60219429D1 (de) 2007-05-24
DE60219429T2 DE60219429T2 (de) 2008-01-03

Family

ID=27256072

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60219429T Expired - Lifetime DE60219429T2 (de) 2001-02-13 2002-02-13 Biochemisches verfahren und vorrichtung zur bestimmung von eigenschaften von proteinen

Country Status (9)

Country Link
US (1) US20040152129A1 (de)
EP (1) EP1360491B1 (de)
JP (1) JP2004527735A (de)
AT (1) ATE359512T1 (de)
AU (1) AU2002229974A1 (de)
DE (1) DE60219429T2 (de)
DK (1) DK1360491T3 (de)
ES (1) ES2284832T3 (de)
WO (1) WO2002065123A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2387903A (en) * 2002-04-24 2003-10-29 Smartbead Technologies Ltd Multiparameter analysis using tagged molecules
GB2395594A (en) * 2002-11-21 2004-05-26 Smartbead Technologies Ltd Bioassay reading system using a computer to locate and identify microlabels by identifying spatially sequential groups or identification codes
GB2412730B (en) * 2004-03-31 2006-08-23 Toshiba Res Europ Ltd An encoded carrier and a method of monitoring a carrier
US8232092B2 (en) * 2005-08-09 2012-07-31 Maxwell Sensors, Inc. Apparatus and method for digital magnetic beads analysis
US7871770B2 (en) * 2005-08-09 2011-01-18 Maxwell Sensors, Inc. Light transmitted assay beads
US7858307B2 (en) * 2005-08-09 2010-12-28 Maxwell Sensors, Inc. Light transmitted assay beads
US20090201504A1 (en) * 2005-08-09 2009-08-13 Maxwell Sensors, Inc. Hydrodynamic focusing for analyzing rectangular microbeads
US8906609B1 (en) 2005-09-26 2014-12-09 Arrowhead Center, Inc. Label-free biomolecule sensor based on surface charge modulated ionic conductance
US9135515B2 (en) 2012-10-22 2015-09-15 Qiagen Gaithersburg, Inc. Automated pelletized sample vision inspection apparatus and methods
US9212976B2 (en) 2013-03-15 2015-12-15 Qiagen Gaithersburg, Inc. Vision-guided aspiration apparatus and methods
WO2017040966A1 (en) * 2015-09-02 2017-03-09 SeLux Diagnostics, Inc. Systems and methods for multiplexed detection of biomarkers

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3322373C2 (de) * 1983-05-19 1986-12-04 Ioannis Dr. 3000 Hannover Tripatzis Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern
US4568630A (en) * 1984-08-24 1986-02-04 Polychrome Corporation Method for preparing and using an anodized aluminum photo-lithographic printing plate
US5206143A (en) * 1985-11-01 1993-04-27 Smithkline Beecham Corporation Method and reagents for performing subset analysis using quantitative differences in fluorescence intensity
CA1337173C (en) * 1989-04-28 1995-10-03 Westaim Biomedical Corp. Thin film diagnostic device
US5129974A (en) * 1990-08-23 1992-07-14 Colorcode Unlimited Corporation Microlabelling system and method of making thin labels
GB9211506D0 (en) * 1992-05-30 1992-07-15 Univ Keele Bar code
EP0763202A4 (de) * 1994-05-23 1998-12-09 Smithkline Beecham Corp Kodierte kombinatorische bibliotheken
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
ATE496288T1 (de) * 1995-10-11 2011-02-15 Luminex Corp Gleichzeitige mehrfachanalyse klinischer proben
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US6001571A (en) * 1995-11-30 1999-12-14 Mandecki; Wlodek Multiplex assay for nucleic acids employing transponders
US6096496A (en) * 1997-06-19 2000-08-01 Frankel; Robert D. Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
US6215894B1 (en) * 1999-02-26 2001-04-10 General Scanning, Incorporated Automatic imaging and analysis of microarray biochips
GB9905807D0 (en) * 1999-03-12 1999-05-05 Amersham Pharm Biotech Uk Ltd Analysis of differential gene expression
US20030134330A1 (en) * 1999-04-15 2003-07-17 Ilya Ravkin Chemical-library composition and method
WO2001044812A1 (en) * 1999-12-15 2001-06-21 Icogen Corporation Method for the simultaneous analysis and detection of multiple analytes by micro identification
DE10031028B4 (de) * 2000-06-26 2008-09-04 Gnothis Holding Sa Verfahren zur Selektion von Partikeln

Also Published As

Publication number Publication date
ES2284832T3 (es) 2007-11-16
EP1360491A2 (de) 2003-11-12
DE60219429T2 (de) 2008-01-03
DK1360491T3 (da) 2007-08-20
AU2002229974A1 (en) 2002-08-28
JP2004527735A (ja) 2004-09-09
WO2002065123A2 (en) 2002-08-22
ATE359512T1 (de) 2007-05-15
EP1360491B1 (de) 2007-04-11
US20040152129A1 (en) 2004-08-05
WO2002065123A3 (en) 2002-12-12

Similar Documents

Publication Publication Date Title
DE60045059D1 (de) Verfahren und Sonden zur Bestimmung der Konzentration von Nukleinsäure-Molekülen und Verfahren zur Analyse der gewonnenen Daten
DE60041355D1 (de) Verfahren zur detektion von erkrankungen
ATE253645T1 (de) Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
ATE212674T1 (de) Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays
ATE394680T1 (de) Verfahren und vorrichtung zur charakterisierung von analyten
WO2003066906A3 (en) Diagnostic microarray and method of use thereof
DE60040483D1 (de) Verfahren und gerät zur nichtinvasiven analyse von blutglucose
DE602004003842D1 (de) Verfahren und automatisiertes Microfluidsystem zum Nachweis von Proteinen in biologischen Proben
DE60219429D1 (de) Biochemisches verfahren und vorrichtung zur bestimmung von eigenschaften von proteinen
ATE334743T1 (de) Verwendung von mit polymer beschichtetem sorptionsmittelkomposit zur trennung, reinigung, entsalzung und konzentrierung von biopolymeren
DE59511098D1 (de) Verfahren zur Früherkennung der Serokonversion eines gegen Hepatitis C-Virus gerichteten Antikörpers
DE69918123D1 (de) Verfahren und reagentiensatz zur erkennung von protein-protein wechselwirkungen
DE60217351D1 (de) Verfahren zur identifizierung von proben eines säugetiers als auch ein kit zur durchführung des verfahrens
ATE318930T1 (de) Nukleinsäuresonden zur detektion von candida- spezies
DE60219428D1 (de) Biochemische methode und apparat zur detektion genetischer charakteristika
ATE299589T1 (de) Verfahren zur bestimmung von substanzen mittels der evaneszenzfeldmethode
DE69717840T2 (de) Nachweis und identifizierung von nicht-polio enteroviren
ATE274188T1 (de) Verfahren zur bestimmung eines analyten und kit dafür
ATE524737T1 (de) Verfahren und vorrichtung zur bestimmung mehrerer analyten mit simultaner internen kontrolle in einer grafischen kombination
DE60043618D1 (de) Verfahren zum nachweis einer reaktion zur molekularen erkennung
RU2007148219A (ru) Способ обнаружения бактерий и тест-набор для их обнаружения
DE60121547D1 (de) Electrochemisches verfahren zum nachweis von nukleinsäuren
ATA216599A (de) Verfahren zur detektion, unterscheidung und quantifizierung von freien und eingekapselten nukleinsäuren in einer probe
WO2003057709A3 (en) Method and reagent for the detection of proteins and peptides
ATE269417T1 (de) Verfahren zur erkennung und messung von gespleisten nukleinsäuren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: HOFFMANN & EITLE, 81925 MUENCHEN